Sexual Health, HIV, and STDs
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1 Sexual Health, HIV, and STDs Richard J. Wolitski, PhD Deputy Director, Behavioral and Social Science Division of HIV/AIDS Prevention Centers for Disease Control & Prevention Fenway Institute, Boston, MA April 27, 2010 The findings and conclusions expressed in this presentation are those of the author and do not necessarily represent the views of the Centers for Disease Control and Prevention.
2 Acknowledgments John Douglas Irene Hall David Purcell
3 Sexual Health, HIV, and STDs Sexual health is not merely the absence of disease But sexually transmitted disease can have a profound effect on sexual health Physical health Mental health Sexual function, satisfaction, and relations Marker for sexual and other health problems
4 Sexual Health of MSM Long history of sexual health disparities Exist within broader context of health inequities Unprotected sex among MSM is increasing HIV and other STDs among MSM are increasing across the US as a whole and elsewhere in the world Access and utilization of prevention services is not optimal Low uptake of Hepatitis A/B vaccine National HIV Behavioral Surveillance About 1 in 5 MSM had participated in an HIV intervention in past year 30% not tested for HIV in past year
5 STD in MSM Now account for majority of U.S. cases of syphilis 46 times as likely to have syphilis than other men 71 times as likely to have syphilis than women (Purcell et al., National STD Prevention Conference, 2010) Evidence of growing role in other STDs GC (20+% of cases in CDC s GISP) Prevalence of GC, CT underestimated due to limited rectal, pharyngeal screening Outbreaks of Lymphogranuloma Venereum (LGV) HPV and anal cancer High rates of HIV co-infection Syphilis 40-60%, GC 5-10%
6 Primary and secondary syphilis, by year and sex: reported rates and male-to-female rate ratios, United States, Males 7 Females 20 Male-Female Rate Ratio Rate (per 100,000 males / females) Male-Female Rate Ratio MSM est. 65% of cases Black MSM est. 20% of cases
7 Primary and secondary syphilis among MSM by race/ethnicity in 23 states, Number of cases * White African American Hispanic * 2007 data are preliminary
8 Gonorrhea Rates: Total and by sex: United States, and the Healthy People 2010 target Rate (per 100,000 population) Male Female Total 2010 Target Note: The Healthy People 2010 target for gonorrhea is 19.0 cases per 100,000 population.
9 Gonococcal Isolate Surveillance Project (GISP) Percent of urethral Neisseria gonorrhoeae isolates obtained from men who have sex with men attending STD clinics, Percent GC in men --est. 22% MSM
10 STD in MSM Sexually Transmitted Hepatitis C Of HIV+ MSM STD clinic patients in Amsterdam 15% HCV+ in May % in April 2008 Associated with: Being HIV-positive IDU (1 in 5 had ever injected) Fisting GHB use Urbanus et al., AIDS, 2009.
11 Estimated Percentage of New HIV Infections, by Transmission Category, 2006* N=56,300 Men who have sex with men and inject drugs, 4% Heterosexual contact, 31% Men who have sex with men, 53% Injection drug users, 12% *50 States and District of Columbia
12 HIV diagnosis rates among MSM, other men, and women--34 states, 2007 HIV/AIDS Rate per 100,000 pop 44x as likely to have HIV dx than other men 40x as likely to have HIV dx than women MSM Other Men Women Purcell et al., National STD Conference, 2010.
13 Estimated HIV Infections by Risk, Race/Ethnicity, and Gender---US, 2006
14 Estimated HIV Infections among MSM by Race/Ethnicity & Age, 2006
15 Estimated Number of New HIV Infections by Transmission Category, *50 States and District of Columbia MSM 32,000 infections each year IDU HET
16 Estimated proportion of HIV transmissions among MSM, Sullivan et al. AIDS 2009, 23:
17 Population-based survey of MSM conducted in San Francisco in 1997 (n = 915) and 2002 (n = 879) Self-reported HIV prevalence increased from 19.6% in 1997 to 26.8% in 2002 Sexual risk behavior also increased Men between ages of 30 and 50 reported largest increase in unprotected anal sex Men between ages of reported largest increase in serosorting
18
19 Summary Epi shows increasing risk and sexually transmitted infections Underlying factors driving these increases worldwide are poorly understood Clear and urgent need for better and more timely longitudinal epi data for MSM Individual behavior as well as interpersonal, social, and community context Need to understand differences by race/ethnicity, age, and HIV status Protective factors/resilience
20 Questions to Consider What do STD and HIV epidemiological data tell us about the overall sexual health of MSM? What other questions do they raise? What sexual health data are missing? Why do inequities in HIV/STD rates exist? What factors are driving increases in STD and HIV infections? What are most effective actions that can be taken (by individuals and public health) to support and improve sexual health of MSM?
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