DIFFERENTE RELAZIONE TRA VALORI PRESSORI E MASSA VENTRICOLARE SX NEI DUE SESSI IN PAZIENTI IPERTESI.
|
|
- Gladys Bridges
- 6 years ago
- Views:
Transcription
1 DIFFERENTE RELAZIONE TRA VALORI PRESSORI E MASSA VENTRICOLARE SX NEI DUE SESSI IN PAZIENTI IPERTESI. Franco Cipollini, Carlo Porta, Enrica Arcangeli, Carla Breschi, & Giuseppe Seghieri Azienda USL 3, Ambulatorio per l Ipertensione Arteriosa, Spedali Riuniti, Pistoia
2 Introduction and Aims of the Study There are evidences to support the hypothesis that women myocardial mass is more susceptible than the male heart to hypertrophy in response to blood pressure load in either humans or in animal models. Furthermore the prediction of cardiovascular morbidity and mortality exerted by left ventricular hypertrophy (LVH) in patients with hypertension seems to be more pronounced in women than in men. The present study was therefore undertaken to investigate the different response between blood pressure, recorded by 24-hour monitoring, and LVM, measured by echocardiographic method, in a population of hypertensive outpatients.
3 Subjects & Methods (1) Population under study The population under study comprised all patients who were consecutively referred by their general practitioners to the outpatient clinic for arterial hypertension of our Hospital (Spedali Riuniti, Pistoia), in order to confirm borderline or white coat hypertension or to modify treatment, where the response to the antihypertensive therapy prescribed at home was judged inadequate. Home therapy was constituted by diuretics, ACE inhibitors, Ca channel blockers and α 1 -blockers alone or in various combination. No difference was present in type of therapy between genders. Diagnosis of diabetes was done according to the anamnestic recall by patients or by measuring fasting plasma glucose (> 7mmol/l).
4 Subjects & Methods (2) Blood pressure was recorded in all patients by a same physician, with a mercury sphygmomanometer, in the sitting position after 10 min rest. The mean of 3 measurements was taken for analysis. Twenty-four hour ambulatory BP was recorded by using an oscillometric device (model SpaceLabs 90207) that was set to take BP readings every 15 min during the day and every 30min during the night. Left ventricular mass (LVM) was measured through echocardiographic method using Devereux s formula [LVM (g)=0.80x(1.04x(d+p+s) 3 -D 3 ) +0.6] and indexed by height 2.7. Comparison between means was performed by using Student s t test. χ 2 test was used to evaluate the significance of differences in proportions. Relations were assessed by Pearson s r correlations coefficients. Multivariate regression analysis model was used to evaluate multiple r and percentage of explained variance of the dependent variablesl. Relative risks, defined as odds ratio, were calculated by using a multiple logistic analysis model. All values are expressed as mean ± SD. The statistical tests were performed by using SAS software for Windows, version 8.2 (SAS Institute Inc., Cary, NC, USA).
5 Results (1) Table 1, shows that women were significantly older, while there was no difference between the sexes in body mass index (BMI) or prevalence of obesity. Twenty-four-hour systolic BP was slightly higher and 24-h diastolic BP significantly lower in women, since, consequently, pulse BP was markedly higher in these latter. Prevalence of hypertension expressed as mean systolic 24-hour BP>125mmHg and/or 24-hour diastolic BP>80mmHg, as well as of diabetes, and previous drug treatment were similar in both genders The left ventricular end-diastolic septal thickness, the posterior wall thickness, as well as the value of not indexed LVM, all measured by echocardiographic method, were significantly higher in men, while after correction for body surface or for height 2.7 LVM values were all together each other not different (Table 2). Left ventricular hypertrophy, present in the 22.5% of males and in 36.4% of females with a near significant preponderance among these latter (p=0.06), was eccentric in over the 70% of cases in both sexes (Table 2). According to the univariate analysis, LVM, indexed by height 2.7 was significantly related to age and to mean 24-hour systolic and pulse BP, while 24-hour diastolic BP was weakly inversely related with LVM only in the female group (r=-0.28; p=0.02). Correlation coefficients between 24-hour pulse pressure and LVM were higher in women than in men (Table 3). These relations remained significant, even after adjusting for possible confounders, as suggested by two separate multiple regression models: the first, which included both systolic and diastolic 24- hour BP into the set of independent covariates and the second which included the 24-hour pulse BP (Table 4).
6 Results (2) Percentage of LVM variance explained by BP values, as expressed by the multiple regression analyses, was on average higher among women than among men (about 55% vs. 45%), and once again 24-hour pulse BP was about sevenfold more important in predicting LVM variance in women than in men (40.77% vs. 6.19%) (Fig. 1). The percent increase in the relative risk of developing LVH (left ventricular mass 47 g/m 2.7 in women and 50 g/m 2.7 in men), expressed by odds-ratios adjusted for main confounders, and estimated for every 1mmHg increase, was ~2.7 times higher in women than in men, either considering the mean 24-hour systolic BP (21.4% vs 8.2%) or the 24-hour mean pulse BP (24.4% vs. 9%) (Table 5). Relative risk of developing LVH due to the increase in 24-hour diastolic blood pressure values was similar in men and in women (~8-10% for every 1mmHg increase), even considering that the odds-ratio value did not reach the full significance in women (10.8; 95%CI: ; Table 5). Non dipping status was related to a significantly higher relative risk of having LVH in women (Odds ratio: 7.88; 95% CI: ) after adjusting for age, diabetes, BMI and therapy, while it wasn t in men (Odds ratio: 2.47; 95% CI: ). All these differences were even more evident including only the hypertensive patients.
7 Conclusions 1. Pulse pressure was more elevated in women, as compared to men, due to a lower diastolic BP in the female gender, 2. LVM values, corrected for height 2.7 were not different in both genders even if left ventricular hypertrophy, eccentric in over the 70% of cases, showed a near significant preponderance among females, 3. LVM was significantly related to age and to mean 24-hour systolic and pulse BP, while 24-hour diastolic BP was weakly inversely related with LVM only in the female group, even after adjusting for possible confounders, 4. LVM variance explained by BP values, was on average higher among women than among men, and, once again, 24-hour pulse BP was about sevenfold more important in predicting LVM variance in women than in men, 5. The relative risk of developing LVH adjusted for main confounders, and estimated for every 1mmHg increase, was ~3 times higher in women than in men, either considering the mean 24-hour systolic and pulse BP, 6. Similarly non dipping status was related to a significant higher relative risk of having LVH in women while it wasn t in men.
8 Women (n=69) Men (n=80) Age (yrs) 51.9± ± Height (cm) 161± ± Weight (Kg) 66.8± ± Body surface area (m 2 ) 1.70± ± BMI (Kg/m 2 ) 25.8± ±3.2 NS 24-h mean systolic BP (mm Hg) 132± ±12.4 NS Office systolic blood pressure (mm Hg) 153.3± ± h mean diastolic BP (mm Hg) 79.4± ± Office diastolic blood pressure (mm Hg) 90.2± ±9.5 NS 24-h mean pulse pressure (mm Hg) 52.3± ± Office pulse pressure (mm Hg) 63± ± Heart rate (beats/min) 72±14 68±13 NS Therapy (%) NS Obesity (%) NS Diabetes (%) 12 8 NS Hypertension (%) NS Table 1 Main characteristics of the study population according to gender P
9 Women (n=69) Men (n=80) Interventricular end-diastolic septal thickness (cm) 1.08± ±0.8 NS Left ventricular end-diastolic diameter (cm) 4.74± ± Posterior wall end-diastolic thickness (cm) 1.08±0.81 1± Relative wall thickness (cm) 0.40± ±0.05 NS Left ventricular mass (g) 160±44 197± Left ventricular mass/body surface area (g/m 2 ) 94.2± ±23.6 NS Left ventricular mass/height 2.7 (g/m 2.7 ) 44.7± ±11.9 NS Left ventricular ejection fraction* 0.65± ±0.08 NS Left ventricular hypertrophy* (%) Eccentric /Concentric hypertrophy (n) 37/5 52/10 NS * Left ventricular mass 47 g/m 2.7 in women and 50 g/m 2.7 in men P Table 2 Echocardiographic findings according to gender
10 Women (n=69) r P Men (n=80) r Age (yrs) h mean systolic BP (mm Hg) Office systolic blood pressure (mm Hg) h mean diastolic BP (mm Hg) NS Office diastolic blood pressure (mm Hg) NS 0.09 NS 24-h mean pulse pressure (mm Hg) Office pulse pressure (mm Hg) P Table 3 Correlation cefficients ( r ) between left ventricular mass and age or blood pressure values
11 a) Women (n=69) Men (n=80) Beta Coefficient P Beta Coefficient P Intercept Age NS Body mass index Diabetes NS Therapy NS NS 24-h mean systolic BP h mean diastolic BP NS b) Women (n=69) Men (n=80) Beta Coefficient P Beta Coefficient P Intercept Age NS Body mass index Diabetes NS Therapy NS NS 24-h mean pulse pressure Table 4 Multiple regression analysis with left ventricular mass as dependent variable, and both 24-h mean BPs a) or 24-h pulse pressure b) as independent variables.
12 Women (n=69) 95%CI Men (n=80) 95%CI 24-h mean systolic BP (mmhg) h mean diastolic BP (mmhg) h mean pulse pressure (mmhg) Office systolic blood pressure (mmhg) Office diastolic blood pressure (mmhg) Office pulse pressure (mmhg) Table 5 - Odds Ratio for LV hypertrophy (left ventricular mass 47 g/m 2.7 in women and 50 g/m 2.7 in men) estimated by every 1mmHg increase in blood pressure in both genders after adjusting for age, body mass index, diabetes, and therapy.
13 % of explained variance Other variables h mean pulse BP 24-h mean diast. BP 24-h mean syst. BP Women Men Women Men Figure 1- Percentage of explained variance of left ventricular mass in male and female subjects by 24h mean blood pressure. Other variables are age, body mass index, diabetes, and previous therapy.
Echocardiographic Correlates of Pulmonary Artery Systolic Pressure
Echocardiographic Correlates of Pulmonary Artery Systolic Pressure The Role of Left Ventricular Diastolic Function Yoram Agmon MD, Shemy Carasso MD, Diab Mutlak MD, Jonathan Lessick MD Dsc, Izhak Kehat
More informationDoes the reduction in systolic blood pressure alone explain the regression of left ventricular hypertrophy?
(24) 18, S23 S28 & 24 Nature Publishing Group All rights reserved 95-92/4 $3. www.nature.com/jhh ORIGINAL ARTICLE Does the reduction in systolic blood pressure alone explain the regression of left ventricular
More informationCARDIOVASCULAR RISK FACTORS & TARGET ORGAN DAMAGE IN GREEK HYPERTENSIVES
CARDIOVASCULAR RISK FACTORS & TARGET ORGAN DAMAGE IN GREEK HYPERTENSIVES C. Liakos, 1 G. Vyssoulis, 1 E. Karpanou, 2 S-M. Kyvelou, 1 V. Tzamou, 1 A. Michaelides, 1 A. Triantafyllou, 1 P. Spanos, 1 C. Stefanadis
More informationHTA ET DIALYSE DR ALAIN GUERIN
HTA ET DIALYSE DR ALAIN GUERIN Cardiovascular Disease Mortality General Population vs ESRD Dialysis Patients 100 Annual CVD Mortality (%) 10 1 0.1 0.01 0.001 25-34 35-44 45-54 55-64 66-74 75-84 >85 Age
More informationPRELIMINARY STUDIES OF LEFT VENTRICULAR WALL THICKNESS AND MASS OF NORMOTENSIVE AND HYPERTENSIVE SUBJECTS USING M-MODE ECHOCARDIOGRAPHY
Malaysian Journal of Medical Sciences, Vol. 9, No. 1, January 22 (28-33) ORIGINAL ARTICLE PRELIMINARY STUDIES OF LEFT VENTRICULAR WALL THICKNESS AND MASS OF NORMOTENSIVE AND HYPERTENSIVE SUBJECTS USING
More informationDr. A. Manjula, No. 7, Doctors Quarters, JLB Road, Next to Shree Guru Residency, Mysore, Karnataka, INDIA.
Original Article In hypertensive patients measurement of left ventricular mass index by echocardiography and its correlation with current electrocardiographic criteria for the diagnosis of left ventricular
More informationEchocardiographic definition of left ventricular hypertrophy in the hypertensive: which method of indexation of left ventricular mass?
Journal of Human Hypertension (1999) 13, 505 509 1999 Stockton Press. All rights reserved 0950-9240/99 $12.00 http://www.stockton-press.co.uk/jhh ORIGINAL ARTICLE Echocardiographic definition of left ventricular
More informationPrognostic significance of blood pressure measured in the office, at home and during ambulatory monitoring in older patients in general practice
(2005) 19, 801 807 & 2005 Nature Publishing Group All rights reserved 0950-9240/05 $30.00 www.nature.com/jhh ORIGINAL ARTICLE Prognostic significance of blood pressure measured in the office, at home and
More informationUniversity of Padova, Padua, Italy, and HARVEST Study Group, Italy
University of Padova, Padua, Italy, and HARVEST Study Group, Italy ISOLATED SYSTOLIC HYPERTENSION IN THE YOUNG DOES NOT IMPLY AN INCREASED RISK OF FUTURE HYPERTENSION NEEDING TREATMENT Mos L, Saladini
More informationThe role of physical activity in the prevention and management of hypertension and obesity
The 1 st World Congress on Controversies in Obesity, Diabetes and Hypertension (CODHy) Berlin, October 26-29 2005 The role of physical activity in the prevention and management of hypertension and obesity
More informationCHAPTER 3 DIABETES MELLITUS, OBESITY, HYPERTENSION AND DYSLIPIDEMIA IN ADULT CENTRAL KERALA POPULATION
CHAPTER 3 DIABETES MELLITUS, OBESITY, HYPERTENSION AND DYSLIPIDEMIA IN ADULT CENTRAL KERALA POPULATION 3.1 BACKGROUND Diabetes mellitus (DM) and impaired glucose tolerance (IGT) have reached epidemic proportions
More informationCoronary artery disease (CAD) risk factors
Background Coronary artery disease (CAD) risk factors CAD Risk factors Hypertension Insulin resistance /diabetes Dyslipidemia Smoking /Obesity Male gender/ Old age Atherosclerosis Arterial stiffness precedes
More informationORIGINAL ARTICLE AMBULATORY BLOOD PRESSURE IN OBESITY. Introduction. Patients and Methods
Vol. 2, Issue 1, pages 31-36 ORIGINAL ARTICLE AMBULATORY BLOOD PRESSURE IN OBESITY By Alejandro de la Sierra, MD Luis M. Ruilope, MD Hypertension Units, Hospital Clinico, Barcelona & Hospital 12 de Octubre,
More informationInterventricular Septum Thickness Predicts Future Systolic Hypertension in Young Healthy Pilots
15 Original Article Hypertens Res Vol.31 (2008) No.1 p.15-20 Interventricular Septum Thickness Predicts Future Systolic Hypertension in Young Healthy Pilots Chagai GROSSMAN 1), Alon GROSSMAN 2), Nira KOREN-MORAG
More informationHypertensive heart disease and failure
Hypertensive heart disease and failure Prof. Dr. Alan Fraser Cardiff University The heart in hypertension Pathophysiology of LV adaptation Regional development of hypertrophy Stress testing - inducible
More informationInternet Journal of Medical Update, Vol. 3, No. 2, Jul-Dec 2008
Evaluation of left ventricular structures in normotensive and hypertensive subjects by two-dimensional echocardiography: Anthropometric correlates in hypertension Mr. Ugwu Anthony Chukwuka * MSc, Mr. Okwor
More informationPrevalence of left ventricular hypertrophy in a hypertensive population
European Heart Journal (1996) 17, 143-149 Prevalence of left ventricular hypertrophy in a hypertensive population J. Tingleff, M. Munch, T. J. Jakobsen, C. Torp-Pedersen, M. E. Olsen, K. H. Jensen, T.
More informationImportance of Ambulatory Blood Pressure Monitoring in Adolescents
Importance of Ambulatory Blood Pressure Monitoring in Adolescents Josep Redon, MD, PhD, FAHA Internal Medicine Hospital Clinico Universitario de Valencia University of Valencia CIBERObn Instituto de Salud
More informationDrug treatments in hypertension outcome studies
The Second Australian National Blood Pressure Study Page 1 of 6 Background Outcome of treatment of hypertension Over the past 25 years studies of the drug treatment of mild-moderate hypertension have demonstrated
More informationHow well do office and exercise blood pressures predict sustained hypertension? A Dundee Step Test Study
(2000) 14, 429 433 2000 Macmillan Publishers Ltd All rights reserved 0950-9240/00 $15.00 www.nature.com/jhh ORIGINAL ARTICLE How well do office and exercise blood pressures predict sustained hypertension?
More informationSeminars in Cardiology, 2003, Vol. 9, No. 3 ISSN SEX-SPECIFIC ANALYSIS OF LEFT VENTRICULAR GEOMETRY IN A POPULATION STUDY IN TALLINN
ORIGINAL PAPERS SEX-SPECIFIC ANALYSIS OF LEFT VENTRICULAR GEOMETRY IN A POPULATION STUDY IN TALLINN Tatjana Shipilova 1, Igor Pshenichnikov 1,JüriKaik 1, Olga Volozh 1, Jelena Abina 1, Maie Kalev 1, Jaanus
More informationAutonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors
Autonomic nervous system, inflammation and preclinical carotid atherosclerosis in depressed subjects with coronary risk factors Carmine Pizzi 1 ; Lamberto Manzoli 2, Stefano Mancini 3 ; Gigliola Bedetti
More informationGALECTIN-3 PREDICTS LONG TERM CARDIOVASCULAR DEATH IN HIGH-RISK CORONARY ARTERY DISEASE PATIENTS
GALECTIN-3 PREDICTS LONG TERM CARDIOVASCULAR DEATH IN HIGH-RISK CORONARY ARTERY DISEASE PATIENTS Table of Contents List of authors pag 2 Supplemental figure I pag 3 Supplemental figure II pag 4 Supplemental
More informationEvaluation of Left Ventricular Function and Hypertrophy Gerard P. Aurigemma MD
Evaluation of Left Ventricular Function and Hypertrophy Gerard P. Aurigemma MD Board Review Course 2017 43 year old health assistant Severe resistant HTN LT BSA 2 Height 64 1 Here is the M mode echocardiogram
More informationLeft ventricular mass in offspring of hypertensive parents: does it predict the future?
ISPUB.COM The Internet Journal of Cardiovascular Research Volume 7 Number 1 Left ventricular mass in offspring of hypertensive parents: does it predict the future? P Jaiswal, S Mahajan, S Diwan, S Acharya,
More informationEgyptian Hypertension Guidelines
Egyptian Hypertension Guidelines 2014 Egyptian Hypertension Guidelines Dalia R. ElRemissy, MD Lecturer of Cardiovascular Medicine Cairo University Why Egyptian Guidelines? Guidelines developed for rich
More informationMasked Hypertension and Aortic Coarctation: Impact on Ventricular Function and Morphology
Masked Hypertension and Aortic Coarctation: Impact on Ventricular Function and Morphology Giovanni Di Salvo MD, PhD, MMSc, FESC BACKGROUND MASKED HYPERTENSION Masked hypertension (MH) consists of an elevated
More informationSupplementary Online Content. Abed HS, Wittert GA, Leong DP, et al. Effect of weight reduction and
1 Supplementary Online Content 2 3 4 5 6 Abed HS, Wittert GA, Leong DP, et al. Effect of weight reduction and cardiometabolic risk factor management on sympton burden and severity in patients with atrial
More informationAntihypertensive Trial Design ALLHAT
1 U.S. Department of Health and Human Services Major Outcomes in High Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic National Institutes
More informationEchocardiography analysis in renal transplant recipients
Original Research Article Echocardiography analysis in renal transplant recipients S.A.K. Noor Mohamed 1*, Edwin Fernando 2, 1 Assistant Professor, 2 Professor Department of Nephrology, Govt. Stanley Medical
More informationIndividual Study Table Referring to Part of Dossier: Volume: Page:
Synopsis Abbott Laboratories Name of Study Drug: Paricalcitol Capsules (ABT-358) (Zemplar ) Name of Active Ingredient: Paricalcitol Individual Study Table Referring to Part of Dossier: Volume: Page: (For
More information4/4/17 HYPERTENSION TARGETS: WHAT DO WE DO NOW? SET THE STAGE BP IN CLINICAL TRIALS?
HYPERTENSION TARGETS: WHAT DO WE DO NOW? MICHAEL LEFEVRE, MD, MSPH PROFESSOR AND VICE CHAIR DEPARTMENT OF FAMILY AND COMMUNITY MEDICINE UNIVERSITY OF MISSOURI 4/4/17 DISCLOSURE: MEMBER OF THE JNC 8 PANEL
More informationRight Ventricular Systolic Dysfunction is common in Hypertensive Heart Failure: A Prospective Study in Sub-Saharan Africa
Right Ventricular Systolic Dysfunction is common in Hypertensive Heart Failure: A Prospective Study in Sub-Saharan Africa 1 Ojji Dike B, Lecour Sandrine, Atherton John J, Blauwet Lori A, Alfa Jacob, Sliwa
More informationSummary of recommendations
Summary of recommendations Measuring blood pressure (BP) Use the recommended technique at every BP reading to ensure accurate measurements and avoid common errs. Pay particular attention to the following:
More informationORIGINAL INVESTIGATION. C-Reactive Protein Concentration and Incident Hypertension in Young Adults
ORIGINAL INVESTIGATION C-Reactive Protein Concentration and Incident Hypertension in Young Adults The CARDIA Study Susan G. Lakoski, MD, MS; David M. Herrington, MD, MHS; David M. Siscovick, MD, MPH; Stephen
More informationRelationship between body mass index, coronary disease extension and clinical outcomes in patients with acute coronary syndrome
Relationship between body mass index, coronary disease extension and clinical outcomes in patients with acute coronary syndrome Helder Dores, Luís Bronze Carvalho, Ingrid Rosário, Sílvio Leal, Maria João
More informationHigh intensity exercise improves cardiac structure and function and reduces liver fat in adults with Type 2 diabetes
High intensity exercise improves cardiac structure and function and reduces liver fat in adults with Type 2 diabetes Sophie Cassidy, s.cassidy@ncl.ac.uk 1) Concentric remodelling 1.2 * Eccentricity ratio
More informationBRIEF COMMUNICATIONS. KEY WORDS: Ambulatory blood pressure monitoring, placebo effect, antihypertensive drug trials.
AJH 1995; 8:311-315 BRIEF COMMUNICATIONS Lack of Placebo Effect on Ambulatory Blood Pressure Giuseppe Mancia, Stefano Omboni, Gianfranco Parati, Antonella Ravogli, Alessandra Villani, and Alberto Zanchetti
More informationHYPERTENSION AND HEART FAILURE
HYPERTENSION AND HEART FAILURE Kenya Cardiac Society Symposium Feb 2017 Dr Jeilan Mohamed No conflict of interests . Geoffrey, 45 yr old hypertensive office worker male from Nairobi, has just watched his
More informationDr. Dermot Phelan MB BCh BAO PhD European Society of Cardiology 2012
Relative Apical Sparing of Longitudinal Strain Using 2- Dimensional Speckle-Tracking Echocardiography is Both Sensitive and Specific for the Diagnosis of Cardiac Amyloidosis. Dr. Dermot Phelan MB BCh BAO
More informationJournal of the American College of Cardiology Vol. 33, No. 6, by the American College of Cardiology ISSN /99/$20.
Journal of the American College of Cardiology Vol. 33, No. 6, 1999 1999 by the American College of Cardiology ISSN 0735-1097/99/$20.00 Published by Elsevier Science Inc. PII S0735-1097(99)00050-9 Familial
More informationPrognostic significance of blood pressure measured on rising
(2001) 15, 413 417 2001 Nature Publishing Group All rights reserved 0950-9240/01 $15.00 www.nature.com/jhh ORIGINAL ARTICLE Prognostic significance of blood pressure measured on rising P Gosse, C Cipriano,
More informationJournal of the American College of Cardiology Vol. 41, No. 6, by the American College of Cardiology Foundation ISSN /03/$30.
Journal of the American College of Cardiology Vol. 41, No. 6, 2003 2003 by the American College of Cardiology Foundation ISSN 0735-1097/03/$30.00 Published by Elsevier Science Inc. doi:10.1016/s0735-1097(03)00052-4
More informationThe athlete s heart: Different training responses in African and Caucasian male elite football players
The athlete s heart: Different training responses in African and Caucasian male elite football players Gard Filip Gjerdalen Oslo University Hospital, Aker. Bjørknes College Co-writers: Hisdal J, Solberg
More informationRelationship between cardiovascular risk factors and traditional Chinese constitution in subjects with high-normal blood pressure
World Journal of Cardiovascular Diseases, 2013, 3, 234-238 http://dx.doi.org/10.4236/wjcd.2013.32036 Published Online April 2013 (http://www.scirp.org/journal/wjcd/) WJCD Relationship between cardiovascular
More informationAbstract ESC Pisa
Abstract ESC 82441 Maximal left ventricular mass-to-power output: A novel index to assess left ventricular performance and to predict outcome in patients with advanced heart failure FL. Dini 1, D. Mele
More informationMareomi Hamada, Go Hiasa, Osamu Sasaki, Tomoaki Ohtsuka, Hidetoshi Shuntaro Ikeda, Makoto Suzuki, Yuji Hara, and Kunio Hiwada
297 Original Article Serum Creatinine Level Renal Involvement Essential Underestimates Hypertensive in Elderly Patients with Hypertension Yuji Shigematsu, Mareomi Hamada, Go Hiasa, Osamu Sasaki, Tomoaki
More informationPrevention of Atrial Fibrillation and Heart Failure in the Hypertensive Patient
Prevention of Atrial Fibrillation and Heart Failure in the Hypertensive Patient The Issue of Primary Prevention of A.Fib. (and Heart Failure) and not the Prevention of Recurrent A.Fib. after Electroconversion
More informationSlide notes: References:
1 2 3 Cut-off values for the definition of hypertension are systolic blood pressure (SBP) 135 and/or diastolic blood pressure (DBP) 85 mmhg for home blood pressure monitoring (HBPM) and daytime ambulatory
More informationONLINE DATA SUPPLEMENT. Impact of Obstructive Sleep Apnea on Left Ventricular Mass and. Diastolic Function
ONLINE DATA SUPPLEMENT Impact of Obstructive Sleep Apnea on Left Ventricular Mass and Diastolic Function Mitra Niroumand Raffael Kuperstein Zion Sasson Patrick J. Hanly St. Michael s Hospital University
More informationBrachial artery hyperaemic blood flow velocity and left ventricular geometry
(2011), 1 5 & 2011 Macmillan Publishers Limited All rights reserved 0950-9240/11 www.nature.com/jhh ORIGINAL ARTICLE Brachial artery hyperaemic blood flow velocity and left ventricular geometry SJ Järhult,
More informationSUPPLEMENTAL MATERIAL
SUPPLEMENTAL MATERIAL Clinical perspective It was recently discovered that small RNAs, called micrornas, circulate freely and stably in human plasma. This finding has sparked interest in the potential
More informationTHE HEART AND HYPERTENSION. Philippe Gosse Hypertension Unit University Hospital Bordeaux
THE HEART AND HYPERTENSION Philippe Gosse Hypertension Unit University Hospital Bordeaux INCREASED LVM Cardiomyocytes hypertrophy is a response to pressure overload This response is influenced by many
More informationDanno d organo bersaglio e rischio CV. Persiste un ruolo prognostico oltre la patologia d organo?
Danno d organo bersaglio e rischio CV. Persiste un ruolo prognostico oltre la patologia d organo? Prof. Massimo Salvetti Clinica Medica University of Brescia Percieved risk Actual risk Sehestedt et al,
More informationUpdate on Current Trends in Hypertension Management
Friday General Session Update on Current Trends in Hypertension Management Shawna Nesbitt, MD Associate Dean, Minority Student Affairs Associate Professor, Department of Internal Medicine Office of Student
More informationDiastolic Heart Failure
Diastolic Heart Failure Presented by: Robert Roberts, M.D., FRCPC, MACC, FAHA, FRSC Professor of Medicine and Chair ISCTR University of Arizona, College of Medicine Phoenix Scientist Emeritus and Advisor,
More informationLONG-TERM EFFECTS OF SURGICAL MENAGEMENT OF PRIMARY ALDOSTERONISM ON THE CARDIOVASCULAR SISTEM
LONG-TERM EFFECTS OF SURGICAL MENAGEMENT OF PRIMARY ALDOSTERONISM ON THE CARDIOVASCULAR SISTEM Riccardo Marsili, Pietro Iacconi, Massimo Chiarugi, Giampaolo Bernini*, Alessandra Bacca*, Paolo Miccoli Department
More informationClinical Study Synopsis
Clinical Study Synopsis This Clinical Study Synopsis is provided for patients and healthcare professionals to increase the transparency of Bayer's clinical research. This document is not intended to replace
More informationComparison of 44-Hour and Fixed 24-Hour Ambulatory Blood Pressure Monitoring in Dialysis Patients
ORIGINAL PAPER Comparison of 44-Hour and Fixed 24-Hour Ambulatory Blood Pressure Monitoring in Dialysis Patients Wenjin Liu, MD; Hong Ye, MD; Bing Tang, MD; Zhiping Sun, MD; Ping Wen, MD; Wenhui Wu, MD;
More informationPatterns of Left Ventricular Remodeling in Chronic Heart Failure: The Role of Inadequate Ventricular Hypertrophy
Abstract ESC 82445 Patterns of Left Ventricular Remodeling in Chronic Heart Failure: The Role of Inadequate Ventricular Hypertrophy FL. Dini 1, P. Capozza 1, P. Fontanive 2, MG. Delle Donne 1, V. Santonato
More informationClinical Updates in the Treatment of Hypertension JNC 7 vs. JNC 8. Lauren Thomas, PharmD PGY1 Pharmacy Practice Resident South Pointe Hospital
Clinical Updates in the Treatment of Hypertension JNC 7 vs. JNC 8 Lauren Thomas, PharmD PGY1 Pharmacy Practice Resident South Pointe Hospital Objectives Review the Eighth Joint National Committee (JNC
More informationHow do we diagnose hypertension today? Presentation Subtitle
How do we diagnose hypertension today? Presentation Subtitle Renata Cífková Case 1 JM, a 64-year-old lady referred to our center because of undesirable effects of her antihypertensive medication Personal
More informationPredictors of unfavorable outcome after atrial septal defect closure in adults
after atrial septal defect closure in adults H. M. Gabriel 1, M. Humenberger 1, R. Rosenhek 1, GP. Diller 2, G. Kaleschke 2, TH. Binder 1, P. Probst 1, G. Maurer 1, H. Baumgartner 2 (1) Medical University
More informationAortic stenosis (AS) is common with the aging population.
New Insights Into the Progression of Aortic Stenosis Implications for Secondary Prevention Sanjeev Palta, MD; Anita M. Pai, MD; Kanwaljit S. Gill, MD; Ramdas G. Pai, MD Background The risk factors affecting
More informationIn white mild to moderate hypertensive patients. Nifedipine Versus Captopril in the Management of Moderate Hypertension in Black ratients
A]H 1994; 7:440^47 Nifedipine Versus Captopril in the Management of Moderate Hypertension in Black ratients John Skoularigis, Leslie Eitzman, Jean Davis, Victor Strugo, and Pinhas Sareli The efficacy of
More informationValue of cardiac rehabilitation Prof. Dr. L Vanhees
Session: At the interface of hypertension and coronary heart disease haemodynamics, heart and hypertension Value of cardiac rehabilitation Prof. Dr. L Vanhees ESC Stockholm August 2010 Introduction There
More informationHypertension Update Warwick Jaffe Interventional Cardiologist Ascot Hospital
Hypertension Update 2008 Warwick Jaffe Interventional Cardiologist Ascot Hospital Definition of Hypertension Continuous variable At some point the risk becomes high enough to justify treatment Treatment
More information80 Appendix A. Fig. A.1 Repository of ABPM information containing measurements of the BP
Appendix A In the first part of the research for developing the initial classifier the data base of 30 patients monitoring during 5 days with 4 readings at day was created for use in the model. The measures
More informationAbstract nr AHA, Chicago November European Heart Journal Cardiovascular Imaging, in press. Nr Peter Blomstrand
Left Ventricular Diastolic Function Assessed by Echocardiography and Tissue Doppler Imaging is a strong Predictor of Cardiovascular Events in Patients with Diabetes Mellitus Type 2 Peter Blomstrand, Martin
More informationDIURNAL VARIATIONS IN BLOOD PRESSURE AND THEIR RELATION WITH CAROTID ARTERY INTIMA-MEDIA THICKENING
DIURNAL VARIATIONS IN BLOOD PRESSURE AND THEIR RELATION WITH CAROTID ARTERY INTIMA-MEDIA THICKENING Sh Narooei (1), B Soroor (2), F Zaker (3) Abstract INTRODUCTION: Hypertension is a very common cardiovascular
More informationJMSCR Vol 04 Issue 05 Page May 2016
www.jmscr.igmpublication.org Impact Factor 5.244 Index Copernicus Value: 5.88 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: http://dx.doi.org/10.18535/jmscr/v4i5.14 Study on ECG Changes in Chronic hypertensive
More informationΑΡΥΙΚΗ ΠΡΟΔΓΓΙΗ ΤΠΔΡΣΑΙΚΟΤ ΑΘΔΝΟΤ. Μ.Β.Παπαβαζιλείοσ Καρδιολόγος FESC - Γιεσθύνηρια ιζμανόγλειον ΓΝΑ Clinical Hypertension Specialist ESH
ΑΡΥΙΚΗ ΠΡΟΔΓΓΙΗ ΤΠΔΡΣΑΙΚΟΤ ΑΘΔΝΟΤ Μ.Β.Παπαβαζιλείοσ Καρδιολόγος FESC - Γιεσθύνηρια ιζμανόγλειον ΓΝΑ Clinical Hypertension Specialist ESH Hypertension Co-Morbidities HTN Commonly Clusters with Other Risk
More informationHow Low Do We Go? Update on Hypertension
How Low Do We Go? Update on Beth L. Abramson, MD, FRCPC, FACC As presented at the University of Toronto s Saturday at the University Session (September 2003) Arecent World Health Organization report states
More informationByeong-Keuk Kim, MD, PhD. Division of Cardiology, Severance Cardiovascular Hospital Yonsei University College of Medicine, Seoul, Korea
Byeong-Keuk Kim, MD, PhD Division of Cardiology, Severance Cardiovascular Hospital Yonsei University College of Medicine, Seoul, Korea BP change (mmhg) from Baseline to 6 Months (mmhg) Catheter-based renal
More informationAldo P. Maggioni, Kees Van Gool, Nelly Biondi, Renato Urso, Niek Klazinga, Roberto Ferrari, Nikolaos Maniadakis and Luigi Tavazzi.
Appropriateness of prescriptions of recommended treatments in OECD health systems: findings based on the Long-Term Registry of the ESC on Heart Failure Aldo P. Maggioni, Kees Van Gool, Nelly Biondi, Renato
More informationCharacteristics and Future Cardiovascular Risk of Patients With Not-At- Goal Hypertension in General Practice in France: The AVANT AGE Study
ORIGINAL PAPER Characteristics and Future Cardiovascular Risk of Patients With Not-At- Goal Hypertension in General Practice in France: The AVANT AGE Study Yi Zhang, MD, PhD; 1 Helene Lelong, MD; 2 Sandrine
More informationANTIHYPERTENSIVE DRUG THERAPY IN CONSIDERATION OF CIRCADIAN BLOOD PRESSURE VARIATION*
Progress in Clinical Medicine 1 ANTIHYPERTENSIVE DRUG THERAPY IN CONSIDERATION OF CIRCADIAN BLOOD PRESSURE VARIATION* Keishi ABE** Asian Med. J. 44(2): 83 90, 2001 Abstract: J-MUBA was a large-scale clinical
More information5.2 Key priorities for implementation
5.2 Key priorities for implementation From the full set of recommendations, the GDG selected ten key priorities for implementation. The criteria used for selecting these recommendations are listed in detail
More informationRisk Assessment of developing type 2 diabetes mellitus in patient on antihypertensive medication
41 Research Article Risk Assessment of developing type 2 diabetes mellitus in patient on antihypertensive medication Amarjeet Singh*, Sudeep bhardwaj, Ashutosh aggarwal Department of Pharmacology, Seth
More informationChapter Two Renal function measures in the adolescent NHANES population
0 Chapter Two Renal function measures in the adolescent NHANES population In youth acquire that which may restore the damage of old age; and if you are mindful that old age has wisdom for its food, you
More informationIdentification of patients with heart failure and PREserved systolic Function : an Epidemiologic Regional study
Identification of patients with heart failure and PREserved systolic Function : an Epidemiologic Regional study Dr. Antonio Magaña M.D. (on behalf I-PREFER investigators group) Stockholm, Sweden, August
More informationClinical cases with Coversyl 10 mg
Clinical cases Coversyl 10 mg For upgraded benefits in hypertension A Editorial This brochure, Clinical cases Coversyl 10 mg for upgraded benefits in hypertension, illustrates a variety of hypertensive
More informationBiostats Final Project Fall 2002 Dr. Chang Claire Pothier, Michael O'Connor, Carrie Longano, Jodi Zimmerman - CSU
Biostats Final Project Fall 2002 Dr. Chang Claire Pothier, Michael O'Connor, Carrie Longano, Jodi Zimmerman - CSU Prevalence and Probability of Diabetes in Patients Referred for Stress Testing in Northeast
More informationJared Moore, MD, FACP
Hypertension 101 Jared Moore, MD, FACP Assistant Program Director, Internal Medicine Residency Clinical Assistant Professor of Internal Medicine Division of General Medicine The Ohio State University Wexner
More informationValidation of the SEJOY BP-1307 upper arm blood pressure monitor for home. blood pressure monitoring according to the European Society of Hypertension
Validation of the SEJOY BP-1307 upper arm blood pressure monitor for home blood pressure monitoring according to the European Society of Hypertension International Protocol revision 2010 Short title: Validation
More informationPrognostic Significance of Left Ventricular Diastolic Dysfunction in Essential Hypertension
Journal of the American College of Cardiology Vol. 39, No. 12, 2002 2002 by the American College of Cardiology Foundation ISSN 0735-1097/02/$22.00 Published by Elsevier Science Inc. PII S0735-1097(02)01896-X
More informationProspective Study of the Changes in Left Ventricular Mass and Geometry Patterns in Hypertensive Patients During 5 Years of Follow-up
Circ J 2005; 69: 1374 1379 Prospective Study of the Changes in Left Ventricular Mass and Geometry Patterns in Hypertensive Patients During 5 Years of Follow-up Alexandra O. Conrady, MD; Oleg G. Rudomanov,
More informationClinical Investigations
Clinical Investigations Echocardiographic Serial Changes of Hypertensive Cardiomyopathy With Severely Reduced Ejection Fraction: Comparison With Idiopathic Dilated Cardiomyopathy Address for correspondence:
More informationAFRICA CARDIOVASCULAR JOURNAL OF AFRICA Vol 23, No 3, April 2012
AFRICA CARDIOVASCULAR JOURNAL OF AFRICA Vol 23, No 3, April 2012 147 Prevalence of residual left ventricular structural changes after one year of antihypertensive treatment in patients of African descent:
More informationEffects of heart rate reduction with ivabradine on left ventricular remodeling and function:
Systolic Heart failure treatment with the If inhibitor ivabradine Trial Effects of heart rate reduction with ivabradine on left ventricular remodeling and function: results of the SHIFT echocardiography
More information& Wilkins. a Division of Cardiology, Schulich Heart Centre, b Institute for Clinical and
Original article 333 Optimum frequency of office blood pressure measurement using an automated sphygmomanometer Martin G. Myers a, Miguel Valdivieso a and Alexander Kiss b,c Objective To determine the
More informationOnline Appendix (JACC )
Beta blockers in Heart Failure Collaborative Group Online Appendix (JACC013117-0413) Heart rate, heart rhythm and prognostic effect of beta-blockers in heart failure: individual-patient data meta-analysis
More informationIntroduction. In Jeong Cho, MD, Wook Bum Pyun, MD and Gil Ja Shin, MD ABSTRACT
ORIGINAL ARTICLE DOI 10.4070 / kcj.2009.39.4.145 Print ISSN 1738-5520 / On-line ISSN 1738-5555 Copyright c 2009 The Korean Society of Cardiology The Influence of the Left Ventricular Geometry on the Left
More informationRationale: Objectives: Indication: Diabetes Mellitus, Type 2 Study Investigators/Centers: 300 physicians in 292 clinics Research Methods: Data Source:
GSK Medicine: N/A Study No.: 112255 Title: A Korean, multi-center, nation-wide, cross-sectional, epidemiology study to identify prevalence of diabetic nephropathy in hypertensive patients with type 2 diabetes
More informationGuidelines on cardiovascular risk assessment and management
European Heart Journal Supplements (2005) 7 (Supplement L), L5 L10 doi:10.1093/eurheartj/sui079 Guidelines on cardiovascular risk assessment and management David A. Wood 1,2 * 1 Cardiovascular Medicine
More informationTHE IMPACT OF CCB AND RAS INHIBITOR COMBINATION THERAPY TO PREVENT CKD INCIDENCE IN HYPERTENSION AND ADVANCED ATHEROSCLEROSIS
THE IMPACT OF CCB AND RAS INHIBITOR COMBINATION THERAPY TO PREVENT CKD INCIDENCE IN HYPERTENSION AND ADVANCED ATHEROSCLEROSIS Daisuke MAEBUCHI, Yasuyuki SHIRAISHI, Hiroaki TANAKA, Yumiko INUI, Makoto TAKEI,
More informationGender-Adjustment and Cutoff Values of Cornell Product in Hypertensive Japanese Patients
CLINICAL STUDY Gender-Adjustment and Cutoff Values of Cornell Product in Hypertensive Japanese Patients Joji Ishikawa, 1 MD, Yuko Yamanaka, 2 MD, Ayumi Toba, 1 MD, Shintaro Watanabe, 3 MD and Kazumasa
More informationDr Doris M. W Kinuthia
Dr Doris M. W Kinuthia Objectives Normal blood pressures in children Measurement of blood pressure in children Aetiology of Hypertension in children Evaluation of children with hypertension Treatment of
More informationHypertriglyceridemia and the Related Factors in Middle-aged Adults in Taiwan
1 Hypertriglyceridemia and the Related Factors in Middle-aged Adults in Taiwan Cheng-Chieh Lin, Tsai-Chung Li 2, Shih-Wei Lai, Kim-Choy Ng 1, Kuo-Che Wang, Chiu-Shong Liu Department of Community Medicine,
More informationDr Diana R Holdright. MD, FRCP, FESC, FACC, MBBS, DA, BSc. Consultant Cardiologist HYPERTENSION.
Dr Diana R Holdright MD, FRCP, FESC, FACC, MBBS, DA, BSc. Consultant Cardiologist HYPERTENSION www.drholdright.co.uk Blood pressure is the pressure exerted on the walls of the arteries when the heart pumps;
More information