new psychoactive substances

Transcription

1 image courtesy of TicTac.org new psychoactive substances

2 new psychoactive substances New psychoactive substances (NPS) (designer drugs, research chemicals, legal highs ) have been emerging onto the recreational drug scene at an unprecedented rate. In parallel the number of substances notified to the Early Warning System (EWS) for the first time is increasing year on year; 13 in 2008, 24 in 2009, 41 in 2010, 49 in 2011 and 73 in It is predicted that this number will exceed 80 for Law enforcement, policy makers, scientists, clinicians, drug support workers and others actively working in this field are left floundering under the ingenuity of the market, and the speed at which it reacts. In general legislation has been effective in reducing use and availability of the controlled substance, but inadvertently spores a plethora of new compounds the substitution effect. As producers of designer drugs have become more creative, so have our methods for monitoring the emergence and usage of these substances. Since user reports are inherently unreliable and ingredients of legal highs are highly variable, analytically confirmed reports are critical for accurate information gathering. However, the availability of reference materials is frequently cited as a major challenge for those tasked with detection. Chiron strive to meet customer demand for NPS reference materials, and work closely with clinical and forensic institutions to this effect. This mini-catalogue lists a wide range of standards for NPS and associated substances [1]. [1] King, L.A. & Nutt, D.J. Deaths from legal highs : a problem of definitions, The Lancet, Volume 383, Issue 9921, Page 952, 15 March 2014, doi: /s (14) New psychoactive substance: a new narcotic or psychotropic drug, in pure form or in preparation, that is not controlled by the 1961 United Nations Single Convention on Narcotic Drugs or the 1971 United Nations Convention on Psychotropic Substances, but which may pose a public health threat comparable to that posed by substances listed in these conventions (Council Decision 2005/387/JHA). EMCDDA Definition

3 Amphetamines ME 100µg/mL K-ME 1000µg/mL DL-Amphetamine, Free base (+/-)-Amphetamine MG MG 50mg MG 100mg ME K-ME DL-Amphetamine Hydrochloride (+/-)-Amphetamine HCl MG MG 50mg MG 100mg MG DL-Amphetamine-d3 Hydrochloride (+/-)-Amphetamine-d3 HCl MG 50mg MG 100mg ME K-ME DL-Amphetamine-d5 Hydrochloride (+/-)-Amphetamine-d5 HCl MG MG 50mg MG 100mg (R)-(-)-Amphetamine Hydrochloride (S)-(+)-Amphetamine Hydrochloride DL-Amphetamine{ring13C6} Sulphate (+/-)-DL-Amphetamine{ring13C6} Sulphate ME ME ME 50µg Base/mL K-ME K-ME MG 5mg ME 100µg/mL DL-Acetylamphetamine (+/-)-Acetylamphetamine K-ME 1000µg/mL MG ME K-ME DL-Amphetamine Sulfate (+/-)-Amphetamine Sulfate MG MG 50mg MG 100mg ME DL-2-Bromoamphetamine Hydrochloride (+/-)-2-Bromoamphetamine HCl K-ME MG ME DL-3-Bromoamphetamine Hydrochloride (+/-)-3-Bromoamphetamine HCl K-ME MG ME DL-4-Bromoamphetamine Hydrochloride (+/-)-4-Bromoamphetamine HCl K-ME MG MG 50mg DL-4-Fluoroamphetamine DL-2-Fluoroamphetamine Hydrochloride DL-3-Fluoroamphetamine Hydrochloride (+/-)-4-Fluoroamphetamine (+/-)-2-Fluoroamphetamine HCl (+/-)-3-Fluoroamphetamine HCl ME ME ME 100µg/mL MG MG MG ME DL-2-Methoxyamphetamine Hydrochloride (+/-)-2-Methoxyamphetamine HCl K-ME MG ME DL-3-Methoxyamphetamine Hydrochloride (+/-)-3-Methoxyamphetamine HCl K-ME MG DL-2-Methylamphetamine Hydrochloride DL-3-Methylamphetamine Hydrochloride DL-4-Methylamphetamine Hydrochloride DL-PMA Hydrochloride (+/-)-2-Methylamphetamine HCl (+/-)-3-Methylamphetamine HCl (+/-)-4-MA, PMA, PAL-313, Aptol (+/-)-PMA HCl ME ME ME ME MG MG MG MG (+/-)-{13C6}-PMA Hydrochloride Ring-{13C6}-4-Methoxyamphetamine HCl ME 50µg Base/mL Methyl Amphetamines ME K-ME DL-Methamphetamine Hydrochloride (+/-)-Methamphetamine HCl MG MG 50mg MG 100mg DL-Methamphetamine-d3 Hydrochloride (+/-)-Methamphetamine-d3 HCl ME ME K-ME DL-Methamphetamine-d5 Hydrochloride (+/-)-Methamphetamine-d5 HCl MG MG 50mg MG 100mg DL-Methamphetamine{ring13C6} Hydrochloride (+/-)-Methamphetamine{ring13C6} HCl ME 50µg Base/mL MG 5mg ME (R)-(-)-Methamphetamine Hydrochloride K-ME MG ME (S)-(+)-Methamphetamine Hydrochloride K-ME MG DL-2-Fluoromethamphetamine Hydrochloride (+/-), DL-2-FMA HCl MG DL-3-Fluoromethamphetamine Hydrochloride (+/-), DL-3-FMA HCl MG ME DL-4-Fluoromethamphetamine Hydrochloride (+/-), DL-4-FMA HCl K-ME MG

4 Methyl Amphetamines Continued ME DL-2-Bromomethamphetamine Hydrochloride 1-(2-Bromophenyl)-N-methylpropan-2-amine HCl K-ME MG ME DL-3-Bromomethamphetamine Hydrochloride 1-(3-Bromophenyl)-N-methylpropan-2-amine HCl K-ME MG ME DL-4-Bromomethamphetamine Hydrochloride 1-(4-Bromophenyl)-N-methylpropan-2-amine HCl K-ME MG DL-2-Methoxymethamphetamine Hydrochloride DL-3-Methoxymethamphetamine Hydrochloride DL-4-Methoxymethamphetamine Hydrochloride (+/-), DL-2-MeOMA HCl, (+/-), DL-OMMA HCl (+/-), DL-3-MeOMA HCl, (+/-), DL-MMMA HCl (+/-)-PMMA HCl K-ME K-ME ME 100µg Acid/mL MG MG MG Ring-{13C6}-4-Methoxymethamphetamine Hydrochloride (+/-)-{13C6}-PMMA HCl ME 50µg Acid/mL DL-2-Methylmethamphetamine Hydrochloride DL-3-Methylmethamphetamine Hydrochloride (+/-), DL-2-MMA HCl (+/-), DL-3-MMA HCl K-ME K-ME MG MG DL-4-Methylmethamphetamine Hydrochloride (+/-), DL-4-MMA HCl (Free base) MG 3,4-Methylenedioxymethamphetamine ME (+/-)-MDMA Hydrochloride (+/-)-MDMA Hydrochloride-d5 3,4-Methylenedioxymethamphetamine HCl, Ecstasy HCl 3,4-Methylenedioxymethamphetamine HCl-D5, Ecstasy HCl-d K-ME MG MG 50mg MG 100mg ME K-ME MG MG 50mg MG 100mg D-MDMA Hydrochloride (+), D-3,4-Methylenedioxymethamphetamine, D-Ecstasy ME L-MDMA Hydrochloride (-), L-3,4-Methylenedioxymethamphetamine, L-Ecstasy ME (+/-)-{13C6}-MDMA Hydrochloride Ring-{13C6}-3,4- Methylenedioxymetamphetamine HCl ME 50µg Base/mL ME (+/-)-MDEA Hydrochloride 3,4-Methylenedioxyethylamphetamine HCl K-ME MG (+/-)-{13C6}-MDEA Hydrochloride ring-13c6-3,4-methylenedioxyethylamphetamine HCl ME 50µg Base/mL ME (+/-)-MDA Hydrochloride K-ME MG ME (+/-)-MDA Hydrochloride-d K-ME MG D-MDA Hydrochloride (+)-3,4-Methylenedioxyamphetamine HCl ME L-MDA Hydrochloride (-)-3,4-Methylenedioxyamphetamine HCl ME (+/-)-{13C6}-MDA Hydrochloride Ring-{13C6}-3,4-Methylenedioxyamphetamine HCl ME 50µg Base/mL Ephedrine (1R,2S)-(-)-Ephedrine ME 100µg/mL (1R,2S)-(-)-Ephedrine Hydrochloride G 1G (1R,2S)-(-)-Ephedrine-d6 Hydrochloride (dimethyl-d6) (1S,2R)-(+)-Ephedrine Hydrochloride ME ME MG G 5mg 1G (1S,2R)-(+)-Ephedrine-d3 Hydrochloride(N-methyl-d3) ME (1R,2S)-(-)-Norephedrine L-(-)-Norephedrine, L-(-)-Phenylpropylamine ME 100µg/mL MG DL-Norephedrine Hydrochloride MG 100mg (1R,2S)-(-)-N-Methylephedrine ME 100µg/mL (1S,2S)-(+)-Pseudoephedrine ME 100µg/mL (1S,2S)-(+)-Pseudoephedrine-d3 Hydrochloride (N-methyl-d3) ME (1R,2R)-(-)-Pseudoephedrine ME 100µg/mL (1R,2R)-(-)-Pseudoephedrine-d3 Hydrochloride (N-methyl-d3) ME D-Norpseudoephedrine Hydrochloride Cathine HCl ME MG

5 Cathinones (+/-)-Cathinone Hydrochloride Benzoylethanamine HCl ME MG (+/-)-Cathinone Hydrochloride-d MG BDB Benzodioxolylbutanamine, 1-(1,3-Benzodioxol-5- yl)butan-2-amine, MBDB metabolite MG Butylone Hydrochloride β-keto MBDB HCl MG Ethylone β-keto MDEA ME 100µg/mL MG 5mg 2-Fluoromethcathinone 2-FMC MG 4-Hydroxymethcathinone MG MBDB N-Methyl-1-(1,3-benzodioxol-5-yl)-2-aminobutane MG Methcathinone Hydrochloride ME MG 4-Methylethcathinone Hydrochloride 4-MEC HCl (Free base) MG 1mg ME Mephedrone Hydrochloride 4-Methylmethcathinone HCl MDPV Methylenedioxypyrovalerone, 1-(1,3-Benzodioxol- 5-yl)-2-(1-pyrrolidinyl)-1-pentanone HCl (Free base) α-pvp Hydrochloride α-pyrrolidinopentiophenone HCl K-ME MG MG 25mg K-ME MG ME MG 2C Phenethylamines ME 2C-B Hydrochloride 4-Bromo-2,5-dimethoxyphenethylamine HCl MG {13C6}-4-Bromo-2,5-dimethoxyphenethylamine Ring-{13C6}-2C-B Hydrochloride ME 50µg Base/mL HCl ME 2C-H Hydrochloride 2,5-Dimethoxyphenethylamine HCl MG Ring-{13C6}-2C-H Hydrochloride {13C6}-2,5-Dimethoxyphenethylamine HCl ME 50µg Base/mL ME 2C-I Hydrochloride 2,5-Dimethoxy-4-iodophenethylamine HCl MG Ring-{13C6}-2C-I Hydrochloride {13C6}-2,5-Dimethoxy-4-iodophenethylamine HCl ME 50µg Base/mL Bk-2C-B 2-Amino- 1- (4- bromo- 2, 5- dimethoxyphenyl) ethanone ME 100µg/mL K-ME 1000µg/mL MG 25C-NBOH Hydrochloride 2C-C-NBOH HCl MG ME 25C-NBOMe Hydrochloride 2C-C-NBOMe HCl, BOM 2C-C, Climbi K-ME MG MG 100mg 25E-NBOMe Hydrochloride 2C-E-NBOMe HCl, BOM 2C-E MG 100mg 2C-T-2 Hydrochloride 2,5-dimethoxy-4-ethylthiophenethylamine MG 100mg Indanes 2-AI MDAI MDAI Hydrochloride MMAI Hydrochloride 2-Aminoindane 5,6-Methylenedioxy-2-aminoindane 5,6-Methylenedioxy-2-aminoindane HCl 5-Methoxy-6-methyl-2-aminoindane HCl ME K-ME K-ME ME 100µg/mL 1000µg/mL K-ME MG MG K-ME 1000µg/mL Benzofuries (APBs and APDBs) 4-APB and 6-APB (Free base) 4- and 6-APB isomer mix / MG 5-APB Hydrochloride α-methyl-5-benzofuranethanamine HCl APB oxalate α-methyl-5-benzofuranethanamine oxalate, 5-(2-Aminopropyl)benzofuran oxalate (Free amine) 6-APB Hydrochloride α-methyl-6-benzofuranethanamine HCl EAPB 5- Benzofuranethanamine, N- ethyl- α- methyl EAPB 6- Benzofuranethanamine, N- ethyl- α- methyl ME K-ME ME K-ME MG ME K-ME MG ME 100µg/mL K-ME 1000µg/mL MG Please enquire

6 Piperazines Piperazine Benzoylpiperazine Benzoylpiperazine-2,2,3,3,5,5,6,6-d8 BZP BZP-D K-ME K-ME ME 1000µg/mL 1000µg/mL 100µg/mL G MG MG 1g ME 3-Chlorophenylpiperazine Hydrochloride m-cpp HCl K-ME MG ME 1-(2,5-Dimethoxybenzyl)piperazine Hydrochloride K-ME MG ME 1-(4-Fluorophenyl)piperazine dihydrochloride FPP K-ME MG para-fluorophenylpiperazine pfpp, 4-fluorophenylpiperazine, 4-FPP, fluoperazine MG 100mg 1-methyl-4-benzylpiperazine Hydrochloride MBZP HCl, Methylbenzylpiperazine HCl MG 100mg ME 100µg/mL 1-(3-Methylbenzyl)piperazine 3-MBZP K-ME 1000µg/mL MG ME 100µg/mL 1-(3-Methoxyphenyl)piperazine 3-MeOPP K-ME 1000µg/mL MG ME 100µg/mL 1-(4-Methoxyphenyl)piperazine 4-MeOPP K-ME 1000µg/mL MG ME 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride Trade name: Trimetazidine K-ME MG Synthetic Cannabinoids AB-PINACA ME 100µg/mL N-(1-Amino-3-methyl-1-oxobutan-2-yl)-1-(pentyl K-ME 1000µg/mL 1H-indazole)-3-carboxamide MG AB-PINACA Metabolite (1-Pentyl-1H-indazole-3-carbonyl)-L-valine ME 100µg/mL 5F-AB-PINACA ME 100µg/mL N- (1- amino- 3- methyl- 1- oxobutan- 2- yl)- 1- ( K-ME 1000µg/mL fluoropentyl)- 1H- indazole- 3- carboxamide MG ME 100µg/mL AB-CHIMINACA K-ME 1000µg/mL MG AB-FUBINACA N-(4-Fluorobenzyl) analogue of AB-PINACA ME 100µg/mL AB-FUBINACA Metabolite (1-(4-Fluorobenzyl)-1H-indazole-3-carbonyl)-Lvaline ME 100µg/mL A-796,260 LTI-258, [1- [2- (4- morpholinyl)ethyl]- 1H- indol- 3- yl](2, 2, 3, 3- tetramethylcyclopropyl)- methanone MG ME 100µg/mL AB Adamantyl-[1-pentyl-1H-indol-3-yl]methanone K-ME 1000µg/mL MG ME 100µg/mL AB-005 [1- [(1- methyl- 2- piperidinyl)methyl]- 1H- indol K-ME 1000µg/mL yl](2, 2, 3, 3- tetramethylcyclopropyl)- methanone MG 5F-AKB48, APINACA 5-fluoropentyl analog, 5F ME 100µg/mL AKB-48-5F APINACA K-ME 1000µg/mL MG AM-694 AM-1248 AM-2201 [1- (5- fluoropentyl)- 1H- indol- 3- yl](2- iodophenyl) K-ME 1000µg/mL methanone MG ME 100µg/mL 1-Adamantyl-[1-[(1-methyl-2-piperidinyl)methyl] K-ME 1000µg/mL 1H-indol-3-yl]methanone MG ME 100µg/mL (1-Naphthalenyl)-(1-(5-fluoropentyl)-1H-indol K-ME 1000µg/mL MG AM Hydroxypentyl metabolite AM-2201 metabolite ME 100µg/mL AM Hydroxyindole metabolite AM-2201 main metabolite ME 50µg/mL MAM-2201 AM-2233 AM-2233 Hydrochloride APICA 5F-APICA APINACA (2-Iodophenyl)-[1-[(1-methyl-2-piperidinyl)methyl]- 1H-indol-3-yl]methanone, HCl ME 50µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG HU-308 4'-Methyl-AM-2201, [1- (5- Fluoropentyl)- 1H- indol- 3- yl](4- methyl- 1- naphthalenyl)- methanone (2-Iodophenyl)-[1-[(1-methyl-2-piperidinyl)methyl]- 1H-indol-3-yl]methanone SDB-001, 2NE1, JWH 018 adamantyl carboxamide STS-135, N-adamantyl-1-fluoropentylindole-3- Carboxamide AKB-48, N-Adamantyl-1-pentylindazole-3- carboxamide (C8)-CP 47,497 rel-5-(1,1-dimethyloctyl)-2-[(1r,3s)-3- hydroxycyclohexyl]phenol ME 100µg/mL HU-210 1,1-Dimethylheptyl-11-hydroxy-THC ME 100µg/mL 4- [4- (1, 1- dimethylheptyl)- 2, 6- dimethoxyphenyl]- 6, 6- dimethyl- bicyclo[3.1.1]hept- 2- ene- 2- methanol MG

7 Synthetic Cannabinoids Continued ME 100µg/mL JWH Pentyl-2-methyl-3-(1-naphthoyl)indole K-ME 1000µg/mL MG JWH-007 N-(5-Hydroxypentyl) metabolite JWH-007 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile JWH-007 COOH JWH-007 PentylCOOH metabolite AN 50µg/mL Acetonitrile JWH-007 COOH-d4 JWH-007 PentylCOOH metabolite-d AN 50µg/mL Acetonitrile JWH-015 JWH-016 (2-Methyl-1-propyl-1H-idol-3-yl)-1- naphthenylmethanone 1-Butyl-2-methyl-3-(1-naphthoyl)indole K-ME 1000µg/mL MG 1000µg/mL ME 100µg/mL K-ME 1000µg/mL MG JWH-016 N-(4-hydroxybutyl) metabolite JWH-016 N-(4-Hydroxybutyl) metabolite AN 50µg/mL Acetonitrile JWH-016 COOH JWH-016 ButylCOOH metabolite AN 50µg/mL Acetonitrile JWH-016 COOH-d4 JWH-016 ButylCOOH metabolite-d AN 50µg/mL Acetonitrile JWH-018 JWH-018-d11 AM-678, 1-Naphthalenyl-(1-pentyl-1H-indol ME 50µg/mL ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL MG 1-Naphthalenyl-(1-pentyl-1H-indol-3- -d11 JWH-018 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile JWH-018 COOH JWH-018 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH-018 COOH-d4 JWH-018 N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH-018 methylderivate (2-methylnaphthalene) (2-Methylnaphthalen-1-yl)-(1-pentyl-1H-indol K-ME 1000µg/mL MG JWH-018 Methylderivate N-(5-Hydroxypentyl) metabolite JWH-018 methylderivate N-(5-hydroxybutyl) metabolite AN 50µg/mL Acetonitrile ME 100µg/mL JWH Heptyl-3-(1-naphthoyl)indole K-ME 1000µg/mL MG ME 100µg/mL JWH Naphthalenyl-(1-pentylpyrrol K-ME 1000µg/mL MG JWH ME 100µg/mL 1- naphthalenyl(1- propyl- 1H- indol- 3- yl) ME 1000µg/mL methanone MG JWH-072-N-carboxy JWH-072 N-Propanoic acid metabolite AN 50µg/mL MG 5mg ME 50µg/mL JWH-073 (1-Butyl-1H-indol-3-yl)-1-naphthalenylmethanone ME 100µg/mL K-ME 1000µg/mL MG JWH-073-d9 (1-Butyl-1H-indol-3-yl)-1-naphthalenylmethanoned MG ME 100µg/mL JWH-073 N-(4-Hydroxybutyl) metabolite JWH-073 N-(4-Hydroxybutyl) metabolite AN 50µg/mL Acetonitrile JWH-073 COOH JWH-073 PentylCOOH metabolite, JWH 073 N-butanoic acid metabolite AN 50µg/mL Acetonitrile JWH-073 COOH-d4 JWH-073 PentylCOOH metabolite-d4, JWH 073 N-butanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH-073 methylderivate (2-methylnaphthalene) 1-Butyl-3-(2-methyl-1-naphthoyl)indole K-ME 1000µg/mL MG JWH-073 methylderivate N-(4-Hydroxybutyl) metabolite JWH-073 Methylderivate N-(4-hydroxybutyl) metabolite AN 50µg/mL Acetonitrile JWH ME 100µg/mL K-ME 1000µg/mL MG JWH-081 COOH JWH-081 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH-081 COOH-d4 JWH-081 N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH Pentyl-2-methyl-3-(4-methoxy-1- naphthoyl)indole ME 100µg/mL K-ME 1000µg/mL MG JWH-098 N-(5-Hydroxypentyl) metabolite JWH-098 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile JWH-098 COOH JWH-098 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH-098 COOH-d4 JWH-098 N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH-122 (4-Methoxyl-1-naphthalenyl)-(1-pentyl-1H-indol-3- (4-Methyl-1-naphthalenyl)-(1-pentyl-1H-indol ME 100µg/mL K-ME 1000µg/mL MG JWH-122-d11 (4-Methyl-1-naphthalenyl)-(1-pentyl-1H-indol-3- -d ME 100µg/mL JWH-122 N-(4-Hydroxypentyl)-metabolite AN 100µg/mL Acetonitrile JWH-122 N-(5-Hydroxypentyl)-metabolite AN 50µg/mL Acetonitrile JWH-122 COOH JWH-122 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH-122 COOH-d4 JWH-122 N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH Hexyl-3-(1-naphthoyl)-5-phenyl-pyrrol MG JWH-200 JWH-203 WIN 55,225; (1-[2-(4-morpholinyl)ethyl]-1H-indol K-ME 1000µg/mL yl]-)-naphthalenylmethanone MG 2-(2-Chlorophenyl)-1-(1-pentyl-1H-indol-3-yl) K-ME 1000µg/mL ethanone MG JWH-203 N-(5-Hydroxypentyl) metabolite JWH-203 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile JWH-203 COOH JWH-203 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH-203 COOH-d4 JWH-203 N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile JWH-210 (4-Ethylnaphthalene-1-yl)(1pentyl-1H-indol K-ME 1000µg/mL JWH-210 COOH JWH-210 N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile JWH (2-Methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl) K-ME 1000µg/mL ethanone MG JWH-250 N-(5-Hydroxypentyl) metabolite JWH-250 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile JWH-250 COOH JWH-250 pentylcooh metabolite AN 50µg/mL Acetonitrile JWH-250 COOH-d4 JWH-250 metabolite-d AN 50µg/mL Acetonitrile JWH (2-Methylphenyl)-1-(1-pentyl-1H-indol-3-yl)- ethanone ME 50µg/mL Acetonitrile

8 Synthetic Cannabinoids Continued... JWH Pentyl-3-(1-naphthoyl)-5-(2-fluorophenyl)-pyrrol PB-22 QUPIC F-PB-22 5-fluoro QUPIC RCS ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG RCS-4 N-(5-Hydroxypentyl) metabolite RCS-4 N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile RCS-4 COOH RCS-N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile RCS-4 COOH-d4 RCS-N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile RCS-4 ortho (2-Methoxyphenyl)-(1-pentyl-1H-indol K-ME 1000µg/mL MG RCS-4 ortho N-(5-Hydroxypentyl) metabolite RCS-4 ortho N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile RCS-4 ortho COOH RCS-4 ortho N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile RCS-4 ortho COOH-d4 RCS-4 ortho N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile RCS-4 meta (3-Methoxyphenyl)-(1-pentyl-1H-indol K-ME 1000µg/mL MG RCS-4 meta N-(5-hydroxypentyl) metabolite RCS-4 meta N-(5-Hydroxypentyl) metabolite AN 50µg/mL Acetonitrile RCS-4 meta COOH RCS-4 meta N-Pentanoic acid metabolite AN 50µg/mL Acetonitrile RCS-4 meta COOH-d4 RCS-4 meta N-Pentanoic acid metabolite-d AN 50µg/mL Acetonitrile RCS-4-4C (1-Butyl-1H-indol-3-yl)(4-methoxyphenyl) K-ME 1000µg/mL methanone MG RCS-8 1-(2-Cyclohexylethyl)-3-(2- methoxyphenylacetyl)indole MG UR-144 UR-144 N-(4-Hydroxypentyl) metabolite URB-597 URB ME 100µg/mL KM-X1 or (1-pentylindol-3-yl)-(2,2,3, K-ME 1000µg/mL tetramethylcycloprop MG ME 100µg/mL (1- (4- hydroxypentyl)- 1H- indol- 3- yl)(2, 2, 3, K-ME 1000µg/mL tetramethylcycloprop MG ME 100µg/mL KSD-4103, [3-(3-Carbamoylphenyl)phenyl] N K-ME 1000µg/mL cyclohexylcarbamate MG ME 100µg/mL 6- methyl- 2- [(4- methylphenyl)amino]- 1- benzoxazin K-ME 1000µg/mL 4- one MG WIN Pravadoline K-ME 1000µg/mL WIN mesylate XLR-11 4-hydroxy SR-19, BTM-4, (4-Methoxyphenyl)-(1-pentyl-1Hindol-3- (R)-(5-methyl-3-(morpholinomethyl)-2,3-dihydro- [1,4]oxazino[2,3,4-hi]indol-6-yl)(naphthalen-1- methanesulfonate (1- (5- fluoro- 4- hydroxypentyl)- 1H- indol- 3- yl)(2, 2, 3, 3- tetramethylcycloprop XLR-11 5-fluoro UR ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL Benzodiazepines Bentazepam Diclazepam 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- 2H-1,4-benzodiazepin-2-one Etizolam Flubromazepam Nifoxipam 3-hydroxyflunitrazepam Nimetazepam Trade name Erimin Phenazepam Hydroxyphenazepam Phenazepam metabolite Phenazepam 4-oxide Phenazepam metabolite Pyrazolam ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG MG 100mg ME 100µg/mL K-ME 1000µg/mL MG Please enquire ME 100µg/mL K-ME 1000µg/mL MG T 100µg/mL Toluene K-T 1000µg/mL Toluene MG MG 50mg MG 100mg T 100µg/mL Toluene K-T 1000µg/mL Toluene MG T 100µg/mL Toluene K-T 1000µg/mL Toluene MG ME 100µg/mL K-ME 1000µg/mL MG

9 Abused or designer pharmaceuticals ME 100µg/mL Desomorphine Krokodil, Dihydrodeoxymorphine MG Dimethylamylamine Hydrochloride DMAA, Methylhexaneamine MG 100mg Etaqualone Hydrochloride Aolon, Athinzone Gabapentin Trade name Neurontin Gabapentin-d (S)-(+)-Pregabalin Trade name Lyrica (S)-(+)-Pregabalin-d4 (aminomethyl d2; hexanoic acid-2,2-d2) ME MG 25mg K-ME 1000µg/mL mg 25mg mg 100mg G 1g K-ME 1000µg/mL MG 5mg MG ME 100µg/mL K-ME 1000µg/mL MG MG 50mg MG 100mg ME 100µg/mL K-ME 1000µg/mL MG MG 25mg K-ME MG ME MG ME 100µg/mL MG MG 200mg ME MG MG 200mg ME 100µg/mL MG ME MG 5mg ME 100µg/mL K-ME 1000µg/mL MG MG 100mg 3,4-CTMP 3,4-Dichloromethylphenidate MG 3,4-CTMP Hydrochloride 3,4-Dichloromethylphenidate HCl MG Propylhexedrine Hydrochloride Hexahydromethamphetamine, Benzedrex, Obesin MG Norpropylhexedrine Hydrochloride Hexahydroamphetamine MG ME O-Desmethyl cis-tramadol Hydrochloride Tramadol metabolite M K-ME MG 25mg O-Desmethyl tramadol-d6 (racemic) Tramadol metabolite M1-d ME 100µg/mL Hydroxybutyrates Sodium gammahydroxybutyrate GHB Na K-ME 1000µg/mL MG 100mg K-ME 1000µg/mL Sodium gammahydroxybutyrate-d6 GHB-d6 Na MG MG 100mg Sodium gammahydroxybutyrate-1,4-13c2 GHB-13C2 Na K-ME 1000µg/mL MG K-ME 1000µg/mL Butyrolactone GBL, gammabutyrolactone MG MG 100mg K-ME 1000µg/mL Butyrolactone-d6 GBL-d6, gammabutyrolactone-d MG MG 100mg Aryl Cyclohexylamines ME K-ME (+/-)-Ketamine Hydrochloride Trade names Ketanest, Ketaset, and Ketalar MG MG 50mg MG 100mg (S)-(+)-Ketamine Hydrochloride ME (+/-)-Norketamine Hydrochloride Ketamine metabolite ME Methoxetamine (MXE) Cyclohexanone, 2- (ethylamino) - 2- ( K-ME 1000µg/mL methanol methoxyphenyl) MG neat neat Phencyclidine Hydrochloride PCP, "Angel dust" MG Phencyclidine-d5 Hydrochloride ME MG Tryptamines & Related Compounds Methylphenidate Hydrochloride (threo) Ritalin Methylphenidate-d9 Hydrochloride (piperidine-d9), (erythro+threo) Ritalinic acid Hydrochloride (threo) Ritalin-d Ritalinic acid (threo) (Free base) Ritalinic acid (erythro) Ritalinic acid-d9 Hydrochloride (piperazine-d9) (erythro+threo) Ethylphenidate α- Phenyl-2- piperidineacetic acid ethyl ester AMT α-mt, Indopan, α-methyltryptamine Please enquire N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-Nmethylpropan-2-amine MG K-ME 1000µg/mL 5-MeO-MiPT 4-Acetylpsilocin fumarate 4-AcO-DMT, psilacetin MG

10 Plant Chemicals Salvinorin A MG ME 100µg/mL (-)-Scopolamine hydrobromide trihydrate Trade names Levo-duboisine, Hyosine MG 100mg MG (+/-)-Cathinone Hydrochloride Benzoylethanamine ME (+/-)-Cathinone Hydrochloride-d MG MG Cathine Hydrochloride D-Norpseudoephedrine HCl ME Other Materials Prolintane Prolintane Nitracaine (R)-(-)-Bromodragonfly Hydrochloride MT-45 Hydrochloride AH-7921 AH-7921-d6 (dimethyl-d6) 1c6, (+)-1-Cyclohexyl-4-( ME diphenylethylpiperazine) HCl MG 5mg 3, 4- Dichloro- N- [[ ME 100µg/mL (dimethylamino) cyclohexyl] methyl] benzamide K-ME 1000µg/mL 3, 4- Dichloro- N- [[ ME 100µg/mL (dimethylamino) cyclohexyl] methyl] benzamide-d K-ME 1000µg/mL ME 100µg/mL Diphenidine K-ME 1000µg/mL MG 10MG Methoxyphenidine ME 100µg/mL (±)-1-[1-(2-Methoxyphenyl) K-ME 1000µg/mL phenylethyl]piperidine MG 2-Methiopropamine 2- Thiopheneethanamine, N, α- dimethyl ME 100µg/mL MG Methiopropamine Hydrochloride MPA HCl MG MG 10MG 4-Methyl-4-methylaminorex p-methyl-4mar MG 3-Diethylamino-2,2-dimethylpropyl-4- nitrobenzoate, 4-nitro-dimethocaine (αr)-8-bromo-α-methyl-benzo[1,2-b:4,5-b']difuran- 4-ethanamine HCl ME 100µg/mL K-ME 1000µg/mL MG ME 100µg/mL K-ME 1000µg/mL MG 10MG ME

11 For ordering and information about prices and delivery in your country please contact your local distributor: NPS _v1, 05-14