Integrating Quality Measures for RA into Your Practice: Optimizing Patient Care Using Your Own Data

Size: px
Start display at page:

Download "Integrating Quality Measures for RA into Your Practice: Optimizing Patient Care Using Your Own Data"

Transcription

1 Integrating Quality Measures for RA into Your Practice: Optimizing Patient Care Using Your Own Data Robin K. Dore, MD Clinical Professor of Medicine David Geffen School of Medicine at UCLA Los Angeles, CA

2 Disclosure of Potential Conflicts of Interest It is the policy of Cedars-Sinai Medical Center to ensure balance, independence, objectivity, and scientific rigor in all of its educational activities. Cedars-Sinai Medical Center assesses conflict of interest with its faculty, planners and managers of CME activities. Conflicts of interest that are identified are resolved by reviewing that presenter s content for fair balance and absence of bias, scientific objectivity of studies utilized in this activity, and patient care recommendations. While Cedars-Sinai Medical Center endeavors to review faculty content, it remains the obligation of each physician or other healthcare practitioner to determine the applicability or relevance of the information provided from this course in his or her own practice. In accordance with the policy of Cedars-Sinai, faculty are asked to disclose any affiliation or financial interest that may affect the content of their presentations.

3 Learning Objectives Identify changes in ACR guidelines for rheumatoid arthritis (RA) Describe how quality of care for patients with RA is currently assessed in one s practice Identify quality data from one s practice that are being reported and locate a summary of the results Formulate a plan for improving key aspects of care being provided to patients with RA

4 Activity Overview Part 1: 30-minute lecture New ACR guidelines Quality assessment what s out there, how can the data be used to inform where practice can be improved Part 2: 60-minute workshop Reflect on local quality processes Share best practices Locate and use your data to improve patient care

5 Please Complete the Pretest Now (Keep packet stapled together)

6 Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

7 2015 ACR Treatment Guidelines: What is Covered? 1. Use of traditional DMARDs, biologic DMARDs, and tofacitinib a. Tapering and discontinuing medications b. Treat-to-target approach 2. Use of glucocorticoids 3. Use of biologics and DMARDs in high-risk populations 4. Use of vaccines in patients starting/receiving DMARDs or biologics 5. Screening for TB 6. Laboratory monitoring for traditional DMARDs Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

8 2015 ACR Treatment Guidelines: What is New? GRADE methodology Early RA Patients Established RA patients High-risk comorbidities Congestive heart failure Hepatitis B Hepatitis C Previous malignancies Serious infection Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

9 Recommendation for Early (and Established) RA Patients Treat-to-Target strategy Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26. Low disease activity or remission

10 Recommendations for Early RA Patients DMARD monotherapy (MTX preferred) recommended over double or triple DMARD therapy > Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

11 Recommendations for Early RA Patients With Moderate or High Disease Activity (Despite DMARD Therapy) Combination of DMARDs or TNFi or non-tnf biologic, +/- MTX > Continuing DMARD monotherapy alone Biologic therapy should be used with MTX over biologic monotherapy, when possible, due to superior efficacy. Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

12 Recommendations for Early RA Patients With Moderate-or High-disease Activity Despite DMARD or Biologic Therapies Conditional recommendations Add low-dose glucocorticoids (prednisone or equivalent 10 mg/day) Add short-term glucocorticoids (< 3 mo) for flares Lowest possible dose Shortest possible duration Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26. Prednisone

13 Treating Early RA Duration < 6 months Strong Conditional Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

14 Recommendations for Established RA Patients For DMARD-naïve patients with low disease activity, we strongly recommend using DMARD monotherapy over a TNFi. TNF Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26. Woodrick RS, Ruderman EM. Nat Rev Rheumatol. 2011;7(11): Accessed Feb 2016.

15 Recommendations for Established RA Patients For moderate-or-high disease activity (despite DMARD monotherapy), we strongly recommend Combination DMARDs or Adding a TNFi or a non-tnf biologic or tofacitinib (all +/- MTX) Biologic therapy should be used in combination with MTX over biologic monotherapy > Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

16 Recommendations for Established RA Patients For moderate or high disease activity despite TNFi monotherapy: One or two DMARDs should be added to the TNFi therapy + TNFi DMARD(s) Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

17 Established RA With Low Disease Activity (Not Remission) Continue DMARD therapy, TNFi, non-tnf biologic or tofacitinib Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

18 Established RA in Remission Strong recommendation against discontinuing all therapies Conditional recommendation for tapering Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

19 Treating Established RA Duration 6 months or 1987 ACR classification criteria Strong Conditional Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

20 TB Screening 2015: Tofacitinib included Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

21 Quality Assessment and Reporting PQRS Quality Measures

22 DMARD Therapy PQRS Measure # 108 Percentage of patients aged 18 years and older who were diagnosed with RA and were prescribed, dispensed, or administered at least one ambulatory prescription for a DMARD. Evidence: Extensive evidence reflected in ACR and EULAR guidelines that treatment has a positive impact. ACR: Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26. EULAR: Smolen JS, et al. Ann Rheum Dis. 2014;73:

23 Tuberculosis Screening PQRS Measure # 176 Percentage of patients aged 18 years and older with a diagnosis of RA who have documentation of a TB screening performed and results interpreted within 6 months prior to receiving a first course of therapy using a biologic diseasemodifying anti-rheumatic drug (DMARD). Evidence: TNF inhibitors increase the risk of both TB and other granulomatous infections. The number of cases of TB was dramatically reduced after screening became standard of care. Woodrick RS, Ruderman EM. Nat Rev Rheumatol. 2011;7(11):

24 PQRS Measure # 177 Periodic Assessment of Disease Activity Percentage of patients aged 18 years and older with a diagnosis of RA who have an assessment and classification of disease activity within 12 months. Rationale: After establishing a diagnosis of RA, risk assessment is crucial for guiding optimal treatment. For the purposes of selecting therapies, physicians should consider the patient s disease activity (low, moderate, or high) at the time of the treatment decisions. Accessed January 2016.

25 Assessing Disease Activity Instrument Acronym Range Remission Routine Assessment of Patient Index Data 3 RAPID Clinical Disease Activity Index CDAI Disease Activity Score 28 (ESR) DAS < 2.6 Simplified Disease Activity Index SDAI Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

26 PQRS Measure # 178 Functional Status Assessment Percentage of patients aged 18 years and older with a diagnosis of RA for whom a functional status assessment was performed at least once within 12 months. ACR Recommendations: Functional status assessment using a standardized, validated measure should be performed routinely for RA patients, at least once per year. Examples: Health Assessment Questionnaire Health Assessment Questionnaire II Multidimensional Health Assessment Questionnaire PROMIS Physical Function 10-item, 20-item PROMIS Physical Function Computerized Adaptive Tests (PROPFCAT) Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26. Maska L, et al. Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S4-13.

27 PQRS Measure # 179 Assessment and Classification of Disease Prognosis Percentage of patients aged 18 years and older with a diagnosis of RA who have an assessment and classification of disease prognosis at least once within 12 months. Evidence: Similar to #177; ACR Content and Voting Panels agreed that disease prognosis was largely captured in the concept of disease activity and that information regarding prognosis was unlikely to further contribute to decisionmaking. Singh JA, et al. Arthritis Rheumatol. 2016;68(1):1-26.

28 Glucocorticoid Management PQRS Measure # 180 Percentage of patients aged 18 years and older with a diagnosis of RA who have been assessed for glucocorticoid use and, for those on prolonged doses of prednisone 10 mg daily (or equivalent) with improvement or no change in disease activity, documentation of glucocorticoid management plan within 12 months. Evidence: Addition of low-dose glucocorticosteroids to synthetic DMARDs improves structural outcomes, decreases inflammatory markers and reduces symptom severity in RA patients. Kavanaugh A, Wells AF. Rheumatology (Oxford). 2014;53(10):

29 Local Practice Quality assessment reporting: who reports what? Data flow: does the quality report accurately reflect clinical practice? Gap between clinical practice and reporting: where is the information lost? (non-entry, wrong entry, limitations of EHS?) Feedback on quality measures. What information do clinicians receive? Closing the loop: How can the reporting process be harnessed to improve patient care?

30 Summary Changes in ACR guidelines may have implications for clinical management Quality measures are based on clinical experience and guidelines Current quality measures are reporting measures, not patient outcome measures How can data from reported quality measures benefit patient care?

31 Integrating New ACR Guidelines for RA into Your Practice: Optimizing Patient Care Using Your Own Data Interactive Workshop

32 Learning Objectives Describe how quality of care for patients with RA is currently assessed in one s practice Identify quality data from one s practice that are being reported and locate a summary of the results Formulate a plan for improving key aspects of care being provided to patients with RA

33 Implementation Workshop Agenda 5 Introduction 5 Individual reflection on quality of care in your practice 10 Small group discussion 10 Facilitated large group discussion 10 Commitment to change (individual), Evaluation

34 5 MINUTES STEP 1: QUALITY MEASURES SURVEY Reflect on Quality Measures in your practice Work on your own to think about quality measures in your practice and barriers that impede optimal patient care. Record your thoughts on the Step 1 handout

35 Small Group Discussion Please Break Into Work Groups With your neighbor, turn around and form a team of 4 with the two neighbors behind you If you are not matched up with a group, join a group that is closest to you Goal is groups of 4-6

36 10 MINUTES Small Group Discussion Discuss your issues and experiences in your group Assessment of quality of care Reporting Data feedback Improving quality of care Describe your situation What was your approach? What difficulties did you face? What were the results/impact of your effort? (Record your groups stories on the worksheet)

37 5 MINUTES Group Activity Moderated discussion on quality assessment, reporting, barriers, and approaches Show of hands: How many of you are actively involved in quality reporting? How many of you have received feedback on quality measures? How many of you have been able to use quality data to improve patient care? Who has a story of how you were able to translate quality measures into clinical practice?

38 10 MINUTES Group Review of Barriers Are there barriers that can be overcome to improve the quality of care provided to patients with RA? Is there a group that discussed this that would like to share their story?

39 5 MINUTES STEP 2 ACTION PLAN Individual Commitment to Change Which barrier in your practice will you address? Use the SMART framework to create your goal What are the first steps you will take? Record your thoughts on the Step 2 worksheet

40 3 MINUTES Choose an Accountability Partner From Your Small Group Invite a partner Share contact information on form provided Phone Project title Commit to follow-up with specific date

41 2 MINUTES Conclusions Moderator to capture essence of discussion Major themes in quality assessment & reporting Common barriers Highlight useful/innovative solutions Best practices for applying quality assessment to patient care

42 Please Complete the Posttest Now

43 Please Complete and Return 1. STEP 1 handout 2. STEP 2 Keep the top sheet, return the carbon copy of your action plan 3. Pretest/posttest 4. Activity evaluation

44 Tools and Resources ACR guidelines Singh JA, et al. Arthritis Rheumatol. 2016;68(1): PQRS measures for RA 2015 Physician Quality Reporting System (PQRS) Measure Specifications Manual for Claims and Registry Reporting of Individual Measures

45 Thank you! For more education please visit:

2016 PQRS. Rheumatiod Arthritis Me asures Group. Measures. Reporting Instructions

2016 PQRS. Rheumatiod Arthritis Me asures Group. Measures. Reporting Instructions Measures #108 Rheumatoid Arthritis (RA): Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy #128 Preventive Care and Screening: Body Mass Index (BMI) Screening and Follow-Up Plan #131 Pain Assessment

More information

TREAT-TO-TARGET IN RHEUMATOID ARTHRITIS

TREAT-TO-TARGET IN RHEUMATOID ARTHRITIS TREAT-TO-TARGET IN RHEUMATOID ARTHRITIS To receive up to 10 CME credits for this activity, complete the evaluation, attestation and post-test answer sheet (minimum passing grade of 70%) and return all

More information

Best Practices in Managing Patients with Rheumatoid Arthritis. Summit Medical Group. Standardizing Protocols and Educating Providers

Best Practices in Managing Patients with Rheumatoid Arthritis. Summit Medical Group. Standardizing Protocols and Educating Providers Best Practices in Managing Patients with Rheumatoid Arthritis Summit Medical Group Standardizing Protocols and Educating Providers Organizational Profile Summit Medical Group, established in 1929, is the

More information

Annual Rheumatology & Therapeutics Review for Organizations & Societies

Annual Rheumatology & Therapeutics Review for Organizations & Societies Annual Rheumatology & Therapeutics Review for Organizations & Societies Comparative Effectiveness Studies of Biologics Learning Objectives Understand the motivation for comparative effectiveness research

More information

Recommendations for RA management: what has changed?

Recommendations for RA management: what has changed? The 2016 Update of the EULAR Recommendations for RA management: what has changed? Baltics Rheumatology Conference Vilnius, September 21-22 Prof. Diego Kyburz University Hospital of Basel Switzerland Multiple

More information

ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION

ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Community Plan Medical Benefit Drug Policy ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION Policy Number: CS2018D0039J Effective Date: March 1, 2018 Table of Contents Page INSTRUCTIONS

More information

Biologic therapy for Rheumatoid arthritis. Paul Etau Ekwom Physician and Rheumatologist

Biologic therapy for Rheumatoid arthritis. Paul Etau Ekwom Physician and Rheumatologist Biologic therapy for Rheumatoid arthritis Paul Etau Ekwom Physician and Rheumatologist Objectives Case presentation of patient with rheumatoid arthritis on a biologic therapy. Discuss biologic therapy

More information

ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION

ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Oxford Clinical Policy Policy Number: PHARMACY 284.9 T2 Effective Date: June 1, 2018 Table of Contents Page INSTRUCTIONS FOR USE...

More information

New Evidence reports on presentations given at EULAR Tocilizumab for the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis

New Evidence reports on presentations given at EULAR Tocilizumab for the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis New Evidence reports on presentations given at EULAR 2011 Tocilizumab for the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis Report on EULAR 2011 presentations Benefit of continuing

More information

1.0 Abstract. Title. Keywords. Rationale and Background

1.0 Abstract. Title. Keywords. Rationale and Background 1.0 Abstract Title A Prospective, Multi-Center Study in Rheumatoid Arthritis Patients on Adalimumab to Evaluate its Effect on Synovitis Using Ultrasonography in an Egyptian Population Keywords Synovitis

More information

ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION

ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION ORENCIA (ABATACEPT) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Commercial Medical Benefit Drug Policy Policy Number: 2018D0039J Effective Date: March 1, 2018 Table of Contents Page INSTRUCTIONS

More information

Fml Limits. Azathioprine (Imuran) 50mg, 75mg, 100mg - $26.85 Cyclosporine, 25mg, 100mg. $ Leflunomide (Arava) 10mg Tablet - $144.

Fml Limits. Azathioprine (Imuran) 50mg, 75mg, 100mg - $26.85 Cyclosporine, 25mg, 100mg. $ Leflunomide (Arava) 10mg Tablet - $144. MEDICATION COVERAGE POLICY PHARMACY AND THERAPEUTICS ADVISORY COMMITTEE POLICY: Rheumatoid Arthritis (RA) P&T DATE: 2/15/2017 CLASS: Rheumatology/Anti-inflammatory Disorders REVIEW HISTORY 2/16, 5/15,

More information

ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION

ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION ACTEMRA (TOCILIZUMAB) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Commercial Medical Benefit Drug Policy Policy Number: 2018D0043I Effective Date: March 1, 2018 Table of Contents Page INSTRUCTIONS

More information

Golimumab: a novel anti-tumor necrosis factor

Golimumab: a novel anti-tumor necrosis factor Golimumab: a novel anti-tumor necrosis factor Rossini M, De Vita S, Ferri C, et al. Biol Ther. 2013. This slide deck represents the opinions of the authors, and not necessarily the opinions of the publisher

More information

II. Requirements Date RFP Issued: 07/11/2013 Use of Patient-Reported Outcome Measures in Management of Rheumatoid Arthritis (RA) I.

II. Requirements Date RFP Issued: 07/11/2013 Use of Patient-Reported Outcome Measures in Management of Rheumatoid Arthritis (RA) I. Pfizer Independent Grants for Learning & Change Request for Proposals (RFP) Rheumatoid Arthritis Patient-Reported Outcome Measures in Management of Rheumatoid Arthritis I. Background The mission of Pfizer

More information

1.0 Abstract. Title. Keywords. Adalimumab, Rheumatoid Arthritis, Effectiveness, Safety. Rationale and Background

1.0 Abstract. Title. Keywords. Adalimumab, Rheumatoid Arthritis, Effectiveness, Safety. Rationale and Background 1.0 Abstract Title Assessment of the safety of adalimumab in rheumatoid arthritis (RA) patients showing rapid progression of structural damage of the joints, who have no prior history of treatment with

More information

Opinion 23 July 2014

Opinion 23 July 2014 The legally binding text is the original French version TRANSPARENCY COMMITTEE Opinion 23 July 2014 IMUREL 50 mg, film-coated tablet (B/100) (CIP: 34009 364 149 0 7) IMUREL 25 mg, film-coated tablet (B/50)

More information

Treat - to - Target Pathway Commissioning Chronic and Complex Care MIDLANDS RHEUMATOLOGY & MUSCULOSKELETAL (MSK) COMMISSIONING NETWORK

Treat - to - Target Pathway Commissioning Chronic and Complex Care MIDLANDS RHEUMATOLOGY & MUSCULOSKELETAL (MSK) COMMISSIONING NETWORK Treat - to - Target Pathway Commissioning Chronic and Complex Care MIDLANDS RHEUMATOLOGY & MUSCULOSKELETAL (MSK) COMMISSIONING NETWORK Dr Bruce Kirkham Consultant Rheumatologist Guy s & St Thomas NHS Foundation

More information

Rheumatoid Arthritis: Challenges and Opportunities in the Evolving Treatment Landscape ReachMD Page 1 of 9

Rheumatoid Arthritis: Challenges and Opportunities in the Evolving Treatment Landscape ReachMD Page 1 of 9 Transcript Details This is a transcript of a continuing medical education (CME) activity accessible on the ReachMD network. Additional media formats for the activity and full activity details (including

More information

Shared Decision Making as a Strategy to Increase Patient Engagement and Achieve Rheumatoid Arthritis Treatment Targets

Shared Decision Making as a Strategy to Increase Patient Engagement and Achieve Rheumatoid Arthritis Treatment Targets A 47-year-old woman with seropositive rheumatoid arthritis (RA), diagnosed earlier this year, wants to establish care with you. She is on methotrexate 20 mg weekly and prednisone 5 mg daily. Her patient

More information

This is a repository copy of Treating active rheumatoid arthritis with Janus kinase inhibitors..

This is a repository copy of Treating active rheumatoid arthritis with Janus kinase inhibitors.. This is a repository copy of Treating active rheumatoid arthritis with Janus kinase inhibitors.. White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/118272/ Version: Accepted

More information

SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION

SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Commercial Medical Benefit Drug Policy SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION Policy Number: PHA031 Effective Date: March 1, 2019 Table of Contents Page COVERAGE RATIONALE...

More information

American College of Rheumatology (ACR) Updated Guideline for the Management of Rheumatoid Arthritis. Public Comments

American College of Rheumatology (ACR) Updated Guideline for the Management of Rheumatoid Arthritis. Public Comments The ACR public comment was posted on the ACR website October 30, 2018. The announcement was e-mailed to the Practice Guidelines Subcommittee, Quality of Care Committee and ACR Board of Directors, and was

More information

Safety and effectiveness of biologic Disease-Modifying Antirheumatic Drugs in elderly patients with rheumatoid arthritis

Safety and effectiveness of biologic Disease-Modifying Antirheumatic Drugs in elderly patients with rheumatoid arthritis 1. Title: Safety and effectiveness of biologic Disease-Modifying Antirheumatic Drugs in elderly patients with rheumatoid arthritis 2. Background: The population of older individuals with rheumatoid arthritis

More information

The use of methotrexate in rheumatological conditions A review of the evidence. Maureen Cox January 2009

The use of methotrexate in rheumatological conditions A review of the evidence. Maureen Cox January 2009 The use of methotrexate in rheumatological conditions A review of the evidence Maureen Cox January 2009 Visser et al Multinational evidence based recommendations for the use of methotrexate in rheumatic

More information

Treatment of Rheumatoid Arthritis: The Past, the Present and the Future

Treatment of Rheumatoid Arthritis: The Past, the Present and the Future Treatment of Rheumatoid Arthritis: The Past, the Present and the Future Lai-Ling Winchow FCP(SA) Cert Rheum(SA) Chris Hani Baragwanath Academic Hospital University of the Witwatersrand Outline of presentation

More information

Supplemental Table 1. Key Inclusion Criteria Inclusion Criterion OPTIMA PREMIER 18 years old with RA (per 1987 revised American College of General

Supplemental Table 1. Key Inclusion Criteria Inclusion Criterion OPTIMA PREMIER 18 years old with RA (per 1987 revised American College of General Supplemental Table 1. Key Inclusion Criteria Inclusion Criterion OPTIMA PREMIER 18 years old with RA (per 1987 revised American College of General Rheumatology classification criteria) 34 ; erythrocyte

More information

Targeting the JAK/STAT Pathway in Immune-mediated Inflammatory Diseases: Current and Future Directions

Targeting the JAK/STAT Pathway in Immune-mediated Inflammatory Diseases: Current and Future Directions Targeting the JAK/STAT Pathway in Immune-mediated Inflammatory Diseases: Current and Future Directions Interim Outcomes Report February 2019 Gilead Sciences, Inc. Grant ID: 02669 Overview Activity Description:

More information

Best Practices in Managing Patients with Rheumatoid Arthritis. University of Rochester. Adding Patient Reported Outcome Measures

Best Practices in Managing Patients with Rheumatoid Arthritis. University of Rochester. Adding Patient Reported Outcome Measures Best Practices in Managing Patients with Rheumatoid Arthritis Adding Patient Reported Outcome Measures Organizational Profile Strong Memorial Hospital is a large tertiary care center located in Rochester,

More information

- Clinical Background, Motivation and my Experience at F2F meeting

- Clinical Background, Motivation and my Experience at F2F meeting Predicting randomized clinical trial results with realworld evidence: A case study in the comparative safety of tofacitinib, adalimumab and etanercept in patients with rheumatoid arthritis - Clinical Background,

More information

2016 PQRS Inflammatory Bowel Disease (IBD) Measures Group

2016 PQRS Inflammatory Bowel Disease (IBD) Measures Group Measures #110 Preventive Care and Screening: Influenza Immunization #111 Pneumonia Vaccination Status for Older Adults #226 Preventive Care and Screening: Tobacco Use: Screening and Cessation Intervention

More information

Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie

Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie 1 Add your company logo here Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie August 13-15, 2014 AIR at UR Developing Best Practice Guidelines for Management of Rheumatoid Arthritis

More information

Rheumatoid arthritis 2010: Treatment and monitoring

Rheumatoid arthritis 2010: Treatment and monitoring October 12, 2010 By Yusuf Yazici, MD [1] The significant changes in the way rheumatoid arthritis has been managed include earlier, more aggressive treatment with combination therapy. Significant changes

More information

RULES TO REDUCE FROM 63 10/25/2013 DISCLOSURES EVIDENCE BASED MEDICINE

RULES TO REDUCE FROM 63 10/25/2013 DISCLOSURES EVIDENCE BASED MEDICINE DISCLOSURES No Conflicts of Interest to Disclose WHICH RA DISEASE ACTIVITY MEASURES TO USE IN PRACTICE Mark Robbins, M.D. MPH Co-Chair Quality Measures ACR Atrius Health - Boston My primary involvement

More information

Pfizer Independent Grants for Learning & Change Request for Proposals (RFP) Rheumatoid Arthritis Mono- and Combination DMARD Therapy in RA Patients

Pfizer Independent Grants for Learning & Change Request for Proposals (RFP) Rheumatoid Arthritis Mono- and Combination DMARD Therapy in RA Patients Pfizer Independent Grants for Learning & Change Request for Proposals (RFP) Rheumatoid Arthritis Mono- and Combination DMARD Therapy in RA Patients I. Background The mission of Pfizer Independent Grants

More information

Comparison of long-term clinical outcome with etanercept and adalimumab treatment of rheumatoid arthritis with respect to immunogenicity

Comparison of long-term clinical outcome with etanercept and adalimumab treatment of rheumatoid arthritis with respect to immunogenicity 7 Comparison of long-term clinical outcome with etanercept and adalimumab treatment of rheumatoid arthritis with respect to immunogenicity Charlotte Krieckaert* Anna Jamnitski* Mike Nurmohamed Piet Kostense

More information

Tuberculosis and Biologic Therapies: Risk and Prevention

Tuberculosis and Biologic Therapies: Risk and Prevention Tuberculosis and Biologic Therapies: Risk and Prevention Kevin L. Winthrop, MD, MPH Associate Professor, Divisions of Infectious Diseases, Public Health and Preventive Medicine Oregon Health & Science

More information

The JAK/STAT Signaling Pathway and its Role in Immune-mediated Inflammatory Disease: Impact on the Treatment of RA

The JAK/STAT Signaling Pathway and its Role in Immune-mediated Inflammatory Disease: Impact on the Treatment of RA The JAK/STAT Signaling Pathway and its Role in Immune-mediated Inflammatory Disease: Impact on the Treatment of RA Final Outcomes Report Gilead Sciences ID: #02668 Series Overview The educational intervention

More information

A new approach to conducting randomized clinical trials in the community setting.

A new approach to conducting randomized clinical trials in the community setting. A new approach to conducting randomized clinical trials in the community setting. IRB # Pro00013241 The TAPIR trial is sponsored by: Vasculitis Clinical Research Consortium (VCRC) National Heart Lung and

More information

Efficacy and Safety of Tocilizumab in the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis

Efficacy and Safety of Tocilizumab in the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis New Evidence reports on presentations given at EULAR 2010 Efficacy and Safety of Tocilizumab in the Treatment of Rheumatoid Arthritis and Juvenile Idiopathic Arthritis Report on EULAR 2010 presentations

More information

Rheumatoid Arthritis: Counseling Women Who Are Trying to Conceive

Rheumatoid Arthritis: Counseling Women Who Are Trying to Conceive Transcript Details This is a transcript of a continuing medical education (CME) activity accessible on the ReachMD network. Additional media formats for the activity and full activity details (including

More information

Regulatory Status FDA- approved indication: Simponi and Simponi ARIA are tumor necrosis factor (TNF) blockers indicated for the treatment of:

Regulatory Status FDA- approved indication: Simponi and Simponi ARIA are tumor necrosis factor (TNF) blockers indicated for the treatment of: Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.70.51 Subject: Simponi / Simponi ARIA Page: 1 of 8 Last Review Date: March 17, 2017 Simponi / Simponi

More information

Inflammatory arthritis, such as rheumatoid arthritis (RA), is

Inflammatory arthritis, such as rheumatoid arthritis (RA), is O r i g i n a l A r t i c l e Using Biologics in Inflammatory Arthritis: Assessing the Risks and Benefits Gina Rohekar MD FRCPC MSc (Clin Epi) About the Author Gina Rohekar is an assistant professor at

More information

Cimzia. Cimzia (certolizumab pegol) Description

Cimzia. Cimzia (certolizumab pegol) Description Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.50.11 Subject: Cimzia Page: 1 of 5 Last Review Date: December 8, 2017 Cimzia Description Cimzia (certolizumab

More information

A Clinical Context Report

A Clinical Context Report Rheumatoid Arthritis in Practice An Expert Commentary with Diane Horowitz, MD A Clinical Context Report Rheumatoid Arthritis in Practice Jointly Sponsored by: and Rheumatoid Arthritis in Practice Expert

More information

Regulatory Status FDA approved indication: Kineret is an interleukin-1 receptor antagonist indicated for: (1)

Regulatory Status FDA approved indication: Kineret is an interleukin-1 receptor antagonist indicated for: (1) Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.70.50 Subject: Kineret Page: 1 of 5 Last Review Date: March 17, 2017 Kineret Description Kineret (anakinra)

More information

New Evidence reports on presentations given at EULAR Tocilizumab for the Treatment of Rheumatoid Arthritis

New Evidence reports on presentations given at EULAR Tocilizumab for the Treatment of Rheumatoid Arthritis New Evidence reports on presentations given at EULAR 2012 Tocilizumab for the Treatment of Rheumatoid Arthritis Report on EULAR 2012 presentations Tocilizumab monotherapy is superior to adalimumab monotherapy

More information

2/29/2016. Disclosures. Learning Objectives

2/29/2016. Disclosures. Learning Objectives Cody Sasek, MPAS, PA C Assistant Professor and Academic Director Physician Assistant Education University of Nebraska Medical Center Omaha, NE Disclosures It is the policy of the University of Nebraska

More information

Clinical Policy: Anakinra (Kineret) Reference Number: CP.PHAR.244 Effective Date: Last Review Date: Line of Business: HIM, Medicaid

Clinical Policy: Anakinra (Kineret) Reference Number: CP.PHAR.244 Effective Date: Last Review Date: Line of Business: HIM, Medicaid Clinical Policy: (Kineret) Reference Number: CP.PHAR.244 Effective Date: 08.16 Last Review Date: 11.18 Line of Business: HIM, Medicaid Coding Implications Revision Log See Important Reminder at the end

More information

This is a repository copy of Psoriasis flare with corticosteroid use in psoriatic arthritis.

This is a repository copy of Psoriasis flare with corticosteroid use in psoriatic arthritis. This is a repository copy of Psoriasis flare with corticosteroid use in psoriatic arthritis. White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/98736/ Version: Accepted Version

More information

New Evidence reports on presentations given at EULAR Safety and Efficacy of Tocilizumab as Monotherapy and in Combination with Methotrexate

New Evidence reports on presentations given at EULAR Safety and Efficacy of Tocilizumab as Monotherapy and in Combination with Methotrexate New Evidence reports on presentations given at EULAR 2009 Safety and Efficacy of Tocilizumab as Monotherapy and in Combination with Methotrexate Report on EULAR 2009 presentations Tocilizumab inhibits

More information

Drug selection in Rheumatoid Arthritis

Drug selection in Rheumatoid Arthritis Drug selection in Rheumatoid Arthritis PROFESSOR KHAN ABUL KALAM AZAD PROFESSOR, DEPARTMENT OF MEDICINE DHAKA MEDICAL COLLEGE Rheumatoid arthritis Autoimmune disease Onset generally occurs between 30 and

More information

Simponi / Simponi ARIA (golimumab)

Simponi / Simponi ARIA (golimumab) Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.70.51 Subject: Simponi / Simponi ARIA Page: 1 of 6 Last Review Date: September 15, 2016 Simponi / Simponi

More information

JAK Inhibition in Rheumatoid Arthritis

JAK Inhibition in Rheumatoid Arthritis Transcript Details This is a transcript of a continuing medical education (CME) activity accessible on the ReachMD network. Additional media formats for the activity and full activity details (including

More information

Patient group: adults with a diagnosis of rheumatoid arthritis (RA)

Patient group: adults with a diagnosis of rheumatoid arthritis (RA) eumusc.net HCQI RA 1 If a patient presents with suspected rheumatoid arthritis (RA) then he/she should be referred to and seen by a specialist (preferably a rheumatologist) for confirmation of diagnosis

More information

Pain: State-of-the-Art Psychiatric and Medical Management

Pain: State-of-the-Art Psychiatric and Medical Management Pain: State-of-the-Art Psychiatric and Medical Management 7:15 A.M. - 4:30 P.M. Psychiatrists, internists, hospitalists, pain management specialists, family physicians, primary care physicians, and allied

More information

Canadian Society of Internal Medicine Annual Meeting 2016 Montreal, QC

Canadian Society of Internal Medicine Annual Meeting 2016 Montreal, QC Canadian Society of Internal Medicine Annual Meeting 2016 Montreal, QC Update on the Treatment of Rheumatoid Arthritis Sabrina Fallavollita MDCM McGill University Canadian Society of Internal Medicine

More information

Regulatory Status FDA- approved indication: Simponi and Simponi ARIA are tumor necrosis factor (TNF) blockers indicated for the treatment of: (2-3)

Regulatory Status FDA- approved indication: Simponi and Simponi ARIA are tumor necrosis factor (TNF) blockers indicated for the treatment of: (2-3) Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.70.51 Subject: Simponi / Simponi ARIA Page: 1 of 9 Last Review Date: March 16, 2018 Simponi / Simponi

More information

Citation for final published version:

Citation for final published version: This is an Open Access document downloaded from ORCA, Cardiff University's institutional repository: http://orca.cf.ac.uk/97756/ This is the author s version of a work that was submitted to / accepted

More information

A 3-page standard protocol to evaluate rheumatoid arthritis (SPERA): Efficient capture of essential data for clinical trials and observational studies

A 3-page standard protocol to evaluate rheumatoid arthritis (SPERA): Efficient capture of essential data for clinical trials and observational studies A 3-page standard protocol to evaluate rheumatoid arthritis (SPERA): Efficient capture of essential data for clinical trials and observational studies T. Pincus Division of Rheumatology and Immunology,

More information

Evaluating Newer Targeted Therapies for Patients with Rheumatoid Arthritis: Addressing Unmet Needs in the Primary Care Practice

Evaluating Newer Targeted Therapies for Patients with Rheumatoid Arthritis: Addressing Unmet Needs in the Primary Care Practice Evaluating Newer Targeted Therapies for Patients with Rheumatoid Arthritis: Addressing Unmet Needs in the Primary Care Practice Provided by Integrity Continuing Education, Inc. Supported by an educational

More information

Relative effect (95% CI) RR LOW 2,3 due to indirectness, imprecision. RR 1.45 (0.43 to 4.84) due to indirectness, imprecision. (0.18 to 20.

Relative effect (95% CI) RR LOW 2,3 due to indirectness, imprecision. RR 1.45 (0.43 to 4.84) due to indirectness, imprecision. (0.18 to 20. Appendix: Evidence Reports Question In patients with early RA with moderate or high disease activity, who are DMARD-naive, what is the impact of combination double DMARD therapy vs. mono-dmard therapy

More information

ABSTRACT INTRODUCTION. Joseph Markenson, MD, 1 Kathryn Charalambous, PhD, 2 Christopher Viereck, PhD, CCMEP, 3 Derek Dietze, MA, FACEHP, CCMEP 3

ABSTRACT INTRODUCTION. Joseph Markenson, MD, 1 Kathryn Charalambous, PhD, 2 Christopher Viereck, PhD, CCMEP, 3 Derek Dietze, MA, FACEHP, CCMEP 3 US Rheumatologists Attitudes, Practice Habits, Barriers, and Knowledge Gaps in Assessing and Monitoring Patients with Rheumatoid Arthritis according to Recent Recommendations Joseph Markenson, MD, 1 Kathryn

More information

Clinical Policy: Etanercept (Enbrel) Reference Number: PA.CP.PHAR.250 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid

Clinical Policy: Etanercept (Enbrel) Reference Number: PA.CP.PHAR.250 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid Clinical Policy: (Enbrel) Reference Number: PA.CP.PHAR.250 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid Coding Implications Revision Log Description (Enbrel ) is tumor necrosis

More information

Patient Engagement Improving Outcomes for Patients with Rheumatoid Arthritis

Patient Engagement Improving Outcomes for Patients with Rheumatoid Arthritis Patient Engagement Improving Outcomes for Patients with Rheumatoid Arthritis Ryan Antolini, M.D. Timothy Gensler, M.D. John Janas, M.D. Presenters Denver Arthritis Clinic Ryan Antolini, M.D. Board Certified

More information

Saturday, April 2, 2016

Saturday, April 2, 2016 FUTURE DIRECTIONS IN PULMONARY AND CRITICAL CARE MEDICINE: 2016 Course DirectoRs Michael I. Lewis, MD and Jeremy A. Falk, MD Conference Location Medical Center Harvey Morse Auditorium South Tower, Plaza

More information

RHEUMATOID ARTHRITIS

RHEUMATOID ARTHRITIS PROGRAM CONTENT AND FAQs The iq&a Interactive Medical Intelligence Zone for RHEUMATOID ARTHRITIS Focus on Established and Novel Immune-Modulating Agents: Mechanisms of Action, Optimizing Efficacy, and

More information

Drug Therapy Guidelines

Drug Therapy Guidelines Simponi, Simponi Aria Applicable Medical Benefit x Effective: 2/13/18 Pharmacy- Formulary 1 x Next Review: 12/18 Pharmacy- Formulary 2 x Date of Origin: 7/2010 Pharmacy- Formulary 3/Exclusive x Review

More information

ABSTRACT. Keywords: Africa; Efficacy; Etanercept; Maintenance therapy; Middle East; Rheumatoid arthritis ORIGINAL RESEARCH

ABSTRACT. Keywords: Africa; Efficacy; Etanercept; Maintenance therapy; Middle East; Rheumatoid arthritis ORIGINAL RESEARCH Rheumatol Ther (2018) 5:149 158 https://doi.org/10.1007/s40744-018-0094-6 ORIGINAL RESEARCH Maintenance of Remission with Etanercept DMARD Combination Therapy Compared with DMARDs Alone in African and

More information

A Framework for Patient-Centered Outcomes Research

A Framework for Patient-Centered Outcomes Research A Framework for Patient-Centered Outcomes Research David H. Hickam, MD, MPH Director of Research Methodology, PCORI Baltimore, MD August 9, 2016 Session Faculty Disclosures David H. Hickam, MD, MPH No

More information

Clinical Policy: Certolizumab (Cimzia) Reference Number: PA.CP.PHAR.247 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid

Clinical Policy: Certolizumab (Cimzia) Reference Number: PA.CP.PHAR.247 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid Clinical Policy: (Cimzia) Reference Number: PA.CP.PHAR.247 Effective Date: 01/18 Last Review Date: 08/17 Line of Business: Medicaid Coding Implications Revision Log Description (Cimzia ) is a tumor necrosis

More information

Cimzia. Cimzia (certolizumab pegol) Description

Cimzia. Cimzia (certolizumab pegol) Description Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 Subject: Cimzia Page: 1 of 5 Last Review Date: March 17, 2017 Cimzia Description Cimzia (certolizumab pegol)

More information

NEW EFFECTIVE TREATMENTS FOR PSORIATIC ARTHRITIS PATIENTS Promising data to support two new drug classes

NEW EFFECTIVE TREATMENTS FOR PSORIATIC ARTHRITIS PATIENTS Promising data to support two new drug classes Annual European Congress of Rheumatology (EULAR) 2017 Madrid, Spain, 14-17 June 2017 NEW EFFECTIVE TREATMENTS FOR PSORIATIC ARTHRITIS PATIENTS Promising data to support two new drug classes Madrid, Spain,

More information

Cimzia. Cimzia (certolizumab pegol) Description

Cimzia. Cimzia (certolizumab pegol) Description Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.50.11 Section: Prescription Drugs Effective Date: April 1, 2018 Subject: Cimzia Page: 1 of 5 Last Review

More information

James R. O Dell, M.D. University of Nebraska Medical Center

James R. O Dell, M.D. University of Nebraska Medical Center Not everyone in the world needs a biologic: Lessons from TEAR and RACAT James R. O Dell, M.D. University of Nebraska Medical Center Disclosure Declaration James O Dell, MD Advisory Board for Crescendo,

More information

The GPs role with biologics for immune-mediated inflammatory diseases David Gardner Rheumatologist GPCME 2015

The GPs role with biologics for immune-mediated inflammatory diseases David Gardner Rheumatologist GPCME 2015 The GPs role with biologics for immune-mediated inflammatory diseases David Gardner Rheumatologist GPCME 2015 The views and opinions expressed in the following presentation are those of the presenter and

More information

UnitedHealthcare Pharmacy Clinical Pharmacy Programs

UnitedHealthcare Pharmacy Clinical Pharmacy Programs Program Number 2017 P 3041-8 Program Step Therapy Medications UnitedHealthcare Pharmacy Clinical Pharmacy Programs *Orencia (abatacept) *This step criteria refers to the subcutaneous formulation of abatacept

More information

We are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists. International authors and editors

We are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists. International authors and editors We are IntechOpen, the world s leading publisher of Open Access books Built by scientists, for scientists 3,700 108,500 1.7 M Open access books available International authors and editors Downloads Our

More information

SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION

SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION UnitedHealthcare Oxford Clinical Policy SIMPONI ARIA (GOLIMUMAB) INJECTION FOR INTRAVENOUS INFUSION Policy Number: PHARMACY 292.4 T2 Effective Date: April 1, 2018 Table of Contents Page INSTRUCTIONS FOR

More information

Open Access. Kayseri Turkey. Keywords: Rheumatoid arthritis, ankylosing spondylitis, recommendations, agreement, physiatrist.

Open Access. Kayseri Turkey. Keywords: Rheumatoid arthritis, ankylosing spondylitis, recommendations, agreement, physiatrist. The Open Rheumatology Journal, 2012, 6, 1-5 1 Open Access Agreement of Turkish Physiatrists with the Assessment in Spondyloarthritis International Society and the European League Against Rheumatism Recommendations

More information

Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie

Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie 1 Rheumatoid Arthritis Learning Collaborative Sponsored by AMGF and AbbVie August 13-15, 2014 Ochsner Best Practices in Managing patients with Rheumatoid Arthritis 2 Medical Group Profile When was your

More information

Regulatory Status FDA-approved indication: Orencia is a selective T cell costimulation modulator indicated for: (1)

Regulatory Status FDA-approved indication: Orencia is a selective T cell costimulation modulator indicated for: (1) Federal Employee Program 1310 G Street, N.W. Washington, D.C. 20005 202.942.1000 Fax 202.942.1125 5.70.18 Subject: Orencia Page: 1 of 6 Last Review Date: December 8, 2017 Orencia Description Orencia (abatacept)

More information

Annual Rheumatology & Therapeutics Review for Organizations & Societies

Annual Rheumatology & Therapeutics Review for Organizations & Societies Annual Rheumatology & Therapeutics Review for Organizations & Societies RA: Update on Biologic Therapy and Step-Up or Step-Down Therapeutic Options Learning Objectives Describe the importance of remission

More information

A Team Approach to Improving Outcomes in Rheumatoid Arthritis: Clinicians, Patients, and Digital Health Coaches

A Team Approach to Improving Outcomes in Rheumatoid Arthritis: Clinicians, Patients, and Digital Health Coaches SYLLABUS AND COURSE GUIDE TV-95-51518-2 A Team Approach to Improving Outcomes in Rheumatoid Arthritis: Clinicians, Patients, and Digital Health Coaches A Free, 9 Minute CME/CNE/ACPE/ABIM(MOC) Live and

More information

University of California, San Diego, School of Medicine, La Jolla, CA, USA; 2

University of California, San Diego, School of Medicine, La Jolla, CA, USA; 2 2194 Long-term (104-Week) Efficacy and Safety Profile of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients With Psoriatic Arthritis: Results From a Phase III, Randomized, Controlled Trial

More information

Principal Investigator. General Information. Conflict of Interest. Certification Published on The YODA Project (

Principal Investigator. General Information. Conflict of Interest. Certification Published on The YODA Project ( Principal Investigator First Name: Liana Last Name: Fraenkel Degree: MD, MPH Primary Affiliation: Yale University School of Medicine E-mail: christine.ramsey@gmail.com Phone number: 610-613-6745 Address:

More information

Vasculitis Update 2017

Vasculitis Update 2017 June 24, 2017 Chicago, Illinois Sponsored by: Office of Continuing Medical Education Division of Rheumatology Vasculitis Clinical Research Consortium Vasculitis Foundation Page 2 About At Northwestern

More information

Best Practices in Managing Patients with Rheumatoid Arthritis. Kelsey-Seybold Clinic. Implementing Evidenced- Based Medicine in the Management of RA

Best Practices in Managing Patients with Rheumatoid Arthritis. Kelsey-Seybold Clinic. Implementing Evidenced- Based Medicine in the Management of RA Best Practices in Managing Patients with Rheumatoid Arthritis Implementing Evidenced- Based Medicine in the Management of RA Organizational Profile (KSC) began in 1949 by founder Dr. Mavis P. Kelsey. Modeling

More information

Clinical Research Applied to Daily Clinical Practice; Learn From Your Colleagues How to Get Answers to Questions you Always Wanted to Ask

Clinical Research Applied to Daily Clinical Practice; Learn From Your Colleagues How to Get Answers to Questions you Always Wanted to Ask Clinical Research Applied to Daily Clinical Practice; Learn From Your Colleagues How to Get Answers to Questions you Always Wanted to Ask Karen Beattie, Ph.D. Assistant Professor Dept. of Medicine McMaster

More information

Rheumatoid Arthritis: When to Start and when to Stop anti-tnf Therapy

Rheumatoid Arthritis: When to Start and when to Stop anti-tnf Therapy Rheumatoid Arthritis: When to Start and when to Stop anti-tnf Therapy [ Cuando iniciar o detener la tx anti-tnf?] Asociacion Costatarricense Medicina Interna August 7, 2015 Arthur Weinstein, MD, FACP,

More information

2017 Blue Cross and Blue Shield of Louisiana

2017 Blue Cross and Blue Shield of Louisiana Applies to all products administered or underwritten by Blue Cross and Blue Shield of Louisiana and its subsidiary, HMO Louisiana, Inc.(collectively referred to as the Company ), unless otherwise provided

More information

Annual European Congress of Rheumatology (EULAR) Madrid, Spain, June 2017

Annual European Congress of Rheumatology (EULAR) Madrid, Spain, June 2017 Annual European Congress of Rheumatology (EULAR) 2017 Madrid, Spain, 14-17 June 2017 NEW DATA SUGGEST NO INCREASED CANCER RISK FOR RA PATIENTS PRESCRIBED BIOLOGICAL DMARDS Reassuring findings may positively

More information

Pharmacy Accreditation

Pharmacy Accreditation RHEUMATOID ARTHRITIS: A FOCUS ON REDUCTION OF DISEASE PROGRESSION AND DISABILITY Geoffrey C. Wall, PharmD, FCCP, BCPS, CGP Professor of Clinical Sciences Drake University College of Pharmacy Internal Medicine

More information

DMARD s in Clinical Practice

DMARD s in Clinical Practice DMARD s in Clinical Practice Professor Md. Mahabubul Islam Majumder Professor & Head, Department of Medicine Comilla Medical College, Comilla Bangladesh Disease-modifying antirheumatic drugs (DMARDs) A

More information

Spondyloarthritis: Practice. New Concepts in. Epidemiology and Clinical

Spondyloarthritis: Practice. New Concepts in. Epidemiology and Clinical New Concepts in Spondyloarthritis: Epidemiology and Clinical Practice Atul Deodhar MD Professor of Medicine Oregon Health & Science University Portland, OR Northwest Rheumatism Society, Seattle, April

More information

London, 1 June 2006 Product name: REMICADE Procedure number: Remicade-H-240-II-73-AR SCIENTIFIC DISCUSSION 1/8

London, 1 June 2006 Product name: REMICADE Procedure number: Remicade-H-240-II-73-AR SCIENTIFIC DISCUSSION 1/8 London, 1 June 2006 Product name: REMICADE Procedure number: Remicade-H-240-II-73-AR SCIENTIFIC DISCUSSION 1/8 1. Introduction Infliximab is a chimeric human-murine IgG1κ monoclonal antibody, which binds

More information

Summary of Risk Minimization Measures

Summary of Risk Minimization Measures Table 6.1.4-1: Summary of Risk Minimization Measures Safety Concern Vaccination Hepatic and renal impairment Combination therapy Elderly Routine Risk Minimization Measures Specific subsection on vaccination

More information

(tofacitinib) are met.

(tofacitinib) are met. Xeljanz (tofacitinib) Policy Number: 5.01. 560 Origination: 3/2014 Last Review: 3/2014 Next Review: 3/2015 Policy BCBSKC will provide coverage for Xeljanz (tofacitinib) when it is determined to be medically

More information

INFLIXIMAB Remicade (infliximab), Inflectra (infliximab-dyyb), Renflexis (infliximab-abda)

INFLIXIMAB Remicade (infliximab), Inflectra (infliximab-dyyb), Renflexis (infliximab-abda) RATIONALE FOR INCLUSION IN PA PROGRAM Background Remicade, Renflexis and Inflectra are tumor necrosis factor (TNFα) blockers. Tumor necrosis factor is an endogenous protein that regulates a number of physiologic

More information