Health research designs: a short play. Jamie Fox Juan M. Lozano
|
|
- Kristina Aubrey Strickland
- 5 years ago
- Views:
Transcription
1 Health research designs: a short play Jamie Fox Juan M. Lozano
2 Compare and contrast common study designs RCT Prospective cohort Retrospective cohort Case control Demonstrate interactive teaching strategies and tools
3
4 But once upon at time.
5
6
7
8 Our PICO question P In healthy men with lots of hair, I (E) does shampooing daily, C O T T as compared with shampooing once or twice weekly, increase the risk of baldness (alopecia)? Type of question: harm Type of study: open..
9 Please take a few minutes (3) to think how you would conduct the following studies to answer the question: RCT Prospective cohort Retrospective cohort Case control
10 Case-control study Exposed to factor Unexposed to factor Exposed to factor Unexposed to factor Sample of individuals without disease Sample of individuals with disease Prospective (concurrent) cohort study Exposed to factor Unexposed to factor No disease Disease No disease Disease Retrospective (historical) cohort study Sample of individuals without disease Past time Exposed to factor Unexposed to factor Trace No disease Disease No disease Disease Present time Available in your workshop folder: tab 5 last page Follow Future time
11
12
13 Randomized controlled trial (RCT) Sample of individuals with hair Shampoo daily Shampoo weekly Hairy Bald Hairy Bald Past time Present time Future time Follow
14
15 Prospective (concurrent) cohort study Sample of individuals with hair Shampoo daily Shampoo weekly Hairy Bald Hairy Bald Past time Present time Future time Follow
16
17 Retrospective (historical) cohort study Sample of individuals with hair Shampoo daily Shampoo weekly Hairy Bald Hairy Bald Track Past time Present time Future time
18
19 Case-control study Shampoo daily Shampoo weekly Sample of bald individuals Shampoo daily Shampoo weekly Sample of hairy individuals Trace Past time Present time Future time
20
21
22 In a study of risk factors for the development of asthma, investigators enrolled consecutive children during their first newborn well child check. The child s caretakers were asked whether or not a dog lived in the house. The children were followed for 5 years and the frequency of asthma in children with and without dogs in their house was assessed. What type of study was this? a. Randomized controlled trial (RCT) b. Prospective cohort c. Retrospective cohort d. Case control
23 In a study of risk factors for the development of asthma, investigators accessed records from a primary care clinic s electronic database. They identified all children with a diagnosis of asthma. They also identified children of similar age and sex who did not have asthma. The investigators then looked to see how many children in each group had dogs in their home before they were diagnosed with asthma. What type of study was this? a. Randomized controlled trial (RCT) b. Prospective cohort c. Retrospective cohort d. Case control
24 In a study of risk factors for the development of asthma, last month investigators accessed records from a primary care clinic s electronic database from The investigators determined which children had a dog in their house at the time of their birth. They then looked to see which children developed asthma by their 5 th birthday. What type of study was this? a. Randomized controlled trial (RCT) b. Prospective cohort c. Retrospective cohort d. Case control
25 In a study of risk factors for the development of asthma, investigators enrolled families for a study during their newborn visit. After enrollment, the investigators used a computer to determine which families would raise a dog or a goldfish in their home. They followed families for 5 years to see which children developed asthma by their 5 th birthday. What type of study was this? a. Randomized controlled trial (RCT) b. Prospective cohort c. Retrospective cohort d. Case control
26
27 Feature Who assigns exposure Direction When Controlled trial Researcher (randomly, ideally) Exposure to outcome Now and future Prospective cohort Retrospective cohort Case - control Other Other Other Exposure to outcome Now and future Exposure to outcome Past Outcome to exposure Past
28 Health research designs: a short play Jamie Fox Juan M. Lozano
Trick or Treat. In April!
Trick or Treat. In April! Take one small envelope but Don t open it! Teaching and Leading EBM 2018 Randomization: simple, stratified and block Juan M. Lozano, MD, MSc Describe three methods of randomization:
More informationUNDERSTANDING EPIDEMIOLOGICAL STUDIES. Csaba P Kovesdy, MD FASN Salem VA Medical Center, Salem VA University of Virginia, Charlottesville VA
UNDERSTANDING EPIDEMIOLOGICAL STUDIES Csaba P Kovesdy, MD FASN Salem VA Medical Center, Salem VA University of Virginia, Charlottesville VA Study design in epidemiological research: Summary Observational
More informationIs Hair Transplant a Safe Option?
Is Hair Transplant a Safe Option? Hair transplant in Delhi, is a permanent solution for your hair when an established form of baldness is established. In most cases the ideal choice works out to be Follicular
More informationCommon Statistical Issues in Biomedical Research
Common Statistical Issues in Biomedical Research Howard Cabral, Ph.D., M.P.H. Boston University CTSI Boston University School of Public Health Department of Biostatistics May 15, 2013 1 Overview of Basic
More informationGATE CAT Intervention RCT/Cohort Studies
GATE: a Graphic Approach To Evidence based practice updates from previous version in red Critically Appraised Topic (CAT): Applying the 5 steps of Evidence Based Practice Using evidence about interventions
More informationOnline Supplementary Material
Section 1. Adapted Newcastle-Ottawa Scale The adaptation consisted of allowing case-control studies to earn a star when the case definition is based on record linkage, to liken the evaluation of case-control
More informationObservational the researcher collects information on attributes or measurements of interest but DOES NOT influence the results.
Distinction between Observational and Experimental Studies Observational the researcher collects information on attributes or measurements of interest but DOES NOT influence the results. Experimental the
More informationCAN EFFECTIVENESS BE MEASURED OUTSIDE A CLINICAL TRIAL?
CAN EFFECTIVENESS BE MEASURED OUTSIDE A CLINICAL TRIAL? Mette Nørgaard, Professor, MD, PhD Department of Clinical Epidemiology Aarhus Universitety Hospital Aarhus, Denmark Danish Medical Birth Registry
More informationEVIDENCE-BASED HEALTH CARE
EVIDENCE-BASED HEALTH CARE AND OTHER MYTHS OF A MODERN AGE Peggy Mancuso, PhD, CNM, RN. 1 An Overview of EBM 2 Evidence-Based Health Care Definition Conscientious, explicit, judicious use Current best
More informationEvidence Based Medicine
Hamadan University of medical sciences School of Public Health Department of Epidemiology Evidence Based Medicine Amin Doosti-Irani, PhD in Epidemiology 10 March 2017 a_doostiirani@yahoo.com 1 Outlines
More informationDepartment of OUTCOMES RESEARCH
Department of OUTCOMES RESEARCH Clinical Research Design Sources of Error Types of Clinical Research Randomized Trials! Daniel I. Sessler, M.D. Professor and Chair Department of OUTCOMES RESEARCH The Cleveland
More informationCYCLE Vanguard: Flow Sheet for Protocol Schedule of Forms + Procedures. Binder Title and Cover Pages. Required Materials Study Schema RC flowsheet
Binder Title and Cover Pages Required Materials Study Schema flowsheet 1 1. Screening a. Screen patient for eligibility. ASAP after ICU admission (within 4 days of mechanical ventilation and 7 days of
More informationProtocol Development: The Guiding Light of Any Clinical Study
Protocol Development: The Guiding Light of Any Clinical Study Susan G. Fisher, Ph.D. Chair, Department of Clinical Sciences 1 Introduction Importance/ relevance/ gaps in knowledge Specific purpose of the
More informationChallenges in design and analysis of large register-based epidemiological studies
FMS/DSBS autumn meeting 2014 Challenges in design and analysis of large register-based epidemiological studies Caroline Weibull & Anna Johansson Department of Medical Epidemiology and Biostatistics (MEB)
More informationCONSORT 2010 checklist of information to include when reporting a randomised trial*
CONSORT 2010 checklist of information to include when reporting a randomised trial* Section/Topic Title and abstract Introduction Background and objectives Item No Checklist item 1a Identification as a
More informationAsthma Management in Pregnancy HEATHER HOWE, MD UNIVERSITY OF UTAH PULMONARY DIVISION
Asthma Management in Pregnancy HEATHER HOWE, MD UNIVERSITY OF UTAH PULMONARY DIVISION Asthma Management in Pregnancy Effects of asthma on pregnancy outcomes Effects of pregnancy on asthma control Management
More informationHealth Studies 315. Clinical Epidemiology: Evidence of Risk and Harm
Health Studies 315 Clinical Epidemiology: Evidence of Risk and Harm 1 Patients encounter (possibly) risky exposures Alcohol during pregnancy (fetal risk) Electromagnetic fields (cancer risk) Vasectomy
More informationMCQ Course in Pediatrics Al Yamamah Hospital June Dr M A Maleque Molla, FRCP, FRCPCH
MCQ Course in Pediatrics Al Yamamah Hospital 10-11 June Dr M A Maleque Molla, FRCP, FRCPCH Q1. Following statements are true in the steps of evidence based medicine except ; a) Convert the need for information
More informationVACCINE ACTIVE SURVEILLANCE I
VACCINE ACTIVE SURVEILLANCE I Caitlin N Dodd, MS Biostatistician, Global Child Health Cincinnati Children s Hospital Medical Center CONTENTS M1 Compare epidemiological study methods Discuss the benefits
More informationCRITICAL APPRAISAL WORKSHEET
1. THE RESEARCH QUESTION CRITICAL APPRAISAL WORKSHEET 1a. What question did the researchers want to answer? About the magnitude of health problem? About the impact of a therapy of some sort? Any differences
More informationIncorporating Clinical Information into the Label
ECC Population Health Group LLC expertise-driven consulting in global maternal-child health & pharmacoepidemiology Incorporating Clinical Information into the Label Labels without Categories: A Workshop
More informationSyncytial Virus. Surveillance: A. Respiratory (RSV) New Initiative for NM
Respiratory Syncytial Virus (RSV) Surveillance: A New Initiative for NM Sarah Shrum, MPH EIP Surveillance Officer, NMDOH EIP Day Conference September 23 rd, 2016 Objectives 1. Describe basic virology,
More informationMethodologies for vaccine safety surveillance. Nick Andrews, Statistics Unit Public Health England October 2015
Methodologies for vaccine safety surveillance Nick Andrews, Statistics Unit Public Health England October 2015 Some dramas of the past 20 years which do you think turned out to be real adverse reactions?
More information115 remained abstinent. 140 remained abstinent. Relapsed Remained abstinent Total
Chapter 10 Exercises 1. Intent-to-treat analysis: Example 1 In a randomized controlled trial to determine whether the nicotine patch reduces the risk of relapse among smokers who have committed to quit,
More information1 Case Control Studies
Statistics April 11, 2013 Debdeep Pati 1 Case Control Studies 1. Case-control (retrospective) study: Select cases, Select controls, Compare cases and controls 2. Cutaneous melanoma (Autier, 1996). 420
More informationAppendix. TABLE E-1 Search Terms
Page 1 Appendix TABLE E-1 Search Terms Category Search Terms* Disease (Chronic) osteomyelitis, osteitis, bone infection Antibiotics Gentamicin, vancomycin, anti-infective agent, (local) antibiotics Properties
More informationImportant Facts About a Hair Transplant Process
Important Facts About a Hair Transplant Process For a considerable amount of time hair loss has been a problem plaguing millions. As your looks are connected to your social life, a receding hairline is
More informationVaccine/toxoid Reimbursement Changes
Vaccine/toxoid Reimbursement Changes Information posted July 3, 2008 This is an update to a banner message that first appeared on the February 29, 2008, Remittance and Status (R&S) Report about the delayed
More informationSampling. (James Madison University) January 9, / 13
Sampling The population is the entire group of individuals about which we want information. A sample is a part of the population from which we actually collect information. A sampling design describes
More informationChoosing the right study design
Choosing the right study design Main types of study design Randomised controlled trial (RCT) Cohort study Case-control study Cross-sectional study Case series/case note review Expert opinion BEST QUALITY
More informationAbout Reading Scientific Studies
About Reading Scientific Studies TABLE OF CONTENTS About Reading Scientific Studies... 1 Why are these skills important?... 1 Create a Checklist... 1 Introduction... 1 Abstract... 1 Background... 2 Methods...
More informationThe Tennessee EHDI Information System
Tracking Babies Along the 1-3-6 Journey The Tennessee EHDI Information System Yinmei Li, MD, PhD State Chronic Disease Epidemiologist Director, Surveillance, Epidemiology and Evaluation Tennessee Department
More informationCanadian Journal of Anesthesia/Journal canadien d anesthésie. Evidence-Based Clinical Updates (EBCU s) in Anesthesia
Canadian Journal of Anesthesia/Journal canadien d anesthésie Evidence-Based Clinical Updates (EBCU s) in Anesthesia INSTRUCTIONS FOR AUTHORS The Canadian Journal of Anesthesia considers for publication
More informationADENIYI MOFOLUWAKE MPH APPLIED EPIDEMIOLOGY WEEK 5 CASE STUDY ASSIGNMENT APRIL
ADENIYI MOFOLUWAKE MPH 510 - APPLIED EPIDEMIOLOGY WEEK 5 CASE STUDY ASSIGNMENT APRIL 4 2013 Question 1: What makes the first study a case-control study? The first case study is a case-control study because
More informationOverview of Study Designs in Clinical Research
Overview of Study Designs in Clinical Research Systematic Reviews (SR), Meta-Analysis Best Evidence / Evidence Guidelines + Evidence Summaries Randomized, controlled trials (RCT) Clinical trials, Cohort
More informationDECLARATION OF CONFLICT OF INTEREST
DECLARATION OF CONFLICT OF INTEREST Warfarin and the risk of major bleeding events in patients with atrial fibrillation: a population-based study Laurent Azoulay PhD 1,2, Sophie Dell Aniello MSc 1, Teresa
More informationStudy Designs. chapter. W hy. L earning O bjectives
holbox/shutterstock holbox/shutterstock chapter 2 Study Designs W hen and W hy Key Questions How do you know when the results of a study are credible? What makes a good study? How do you decide which kind
More informationOverview of Study Designs
Overview of Study Designs Kyoungmi Kim, Ph.D. July 13 & 20, 2016 This seminar is jointly supported by the following NIH-funded centers: We are video recording this seminar so please hold questions until
More informationGuidelines for Writing and Reviewing an Informed Consent Manuscript From the Editors of Clinical Research in Practice: The Journal of Team Hippocrates
Guidelines for Writing and Reviewing an Informed Consent Manuscript From the Editors of Clinical Research in Practice: The Journal of Team Hippocrates 1. Title a. Emphasize the clinical utility of the
More informationRESEARCH PROJECT. Comparison of searching tools and outcomes of different providers of the Medline database (OVID and PubMed).
RESEARCH PROJECT Comparison of searching tools and outcomes of different providers of the Medline database (OVID and PubMed). Karolina Kucerova Charles University in Prague Evidence-Based Medicine Course
More informationResearch Methodology Workshop. Study Type
Research Methodology Workshop Study Type What type of question? Frequency: how common is it? Aetiology: What caused this? Intervention: Does this intervention work? Diagnosis or test evaluation: How accurate
More informationWhen a Threshold Crossing approach may and may not be appropriate: A Case Study in SMA
When a Threshold Crossing approach may and may not be appropriate: A Case Study in SMA EFSPI Regulatory Statistics Workshop, 24-25 th September 2018 Carol Reid and Uli Burger picture placeholder Outline
More informationDr. Engle has received an unrestricted educational grant for the MD Anderson Pain Medicine Fellowship.
Mitchell Engle, MD, PhD Dr. Mitchell Engle earned his medical degree and a Ph.D. in Pharmacology from the University Of Iowa Carver College Of Medicine. His Ph.D. research examined the role of the spinal
More informationNewborn Screening Issues and Answers Workshop: Laboratory Health Information Exchange November 1-2, Utah Department of Health
Newborn Issues and Answers Workshop: Laboratory Health Information Exchange November 1-2, 2010 User Group Access Method Query / Display Software IHC HELP2 Webkids in HELP2, querying directly and displaying
More informationEVIDENCE DETECTIVES December 28, 2005 Edward Amores, M.D. Reviewed and edited by P. Wyer, M.D. Part I Question Formulation
EVIDENCE DETECTIVES December 28, 2005 Edward Amores, M.D. Reviewed and edited by P. Wyer, M.D. Part I Question Formulation Clinical Scenario Quite often in the Pediatric ED and at times in the adult ED
More informationScientific Evidences in Homeopathy: a dynamic database
Scientific Evidences in Homeopathy: a dynamic database Introduction. Rationale. Instructions for use A. Scientific Research in the Era of EBM B. Scientific Research in Homeopathic Medicine: peculiarities
More informationThe Cumulative Incidence of HIV Infection in HIVexposed Infants with a Birth Weight of 1500g Receiving Breast Milk and Daily Nevirapine
The Cumulative Incidence of HIV Infection in HIVexposed Infants with a Birth Weight of 1500g Receiving Breast Milk and Daily Nevirapine A retrospective, descriptive study conducted at Kalafong hospital,
More informationTrial Designs. Professor Peter Cameron
Trial Designs Professor Peter Cameron OVERVIEW Review of Observational methods Principles of experimental design applied to observational studies Population Selection Looking for bias Inference Analysis
More informationSystematic reviews: From evidence to recommendation. Marcel Dijkers, PhD, FACRM Icahn School of Medicine at Mount Sinai
Systematic reviews: From evidence to recommendation Session 2 - June 18, 2014 Going beyond design, going beyond intervention: The American Academy of Neurology (AAN) Clinical Practice Guideline process
More informationThings to Consider Before You Plan For a Hair Transplant
Things to Consider Before You Plan For a Hair Transplant Planning to visit a hair transplant surgeon in Delhi? A surgery is the last thing on your mind when you have gone bald. The main thing is that it
More informationZoonotic Disease Report June 03 June 09, 2018 (Week 23)
Zoonotic Disease Report June 03 June 09, 2018 (Week 23) Executive Summary Statewide 180 specimens have tested positive for rabies in 2018. This surpasses total positive specimens for all of 2017. 2018
More informationTool to Assess Risk of Bias in Cohort Studies
Tool to Assess Risk of Bias in Cohort Studies Contributed by the CLARITY Group at McMaster University 1. Was selection of exposed and non-exposed cohorts drawn from the same population? Exposed and unexposed
More informationVaccination Recommendations Practice and Shelter-Housed Dogs
Vaccination Recommendations Practice and Shelter-Housed Dogs 1. MIXING VACCINES. Can different types of vaccines be mixed in the same syringe? No. Unless specifically stated on the product label (package
More informationPICO Presentation: A review of the research RACHEL FOX COHP 450
PICO Presentation: A review of the research RACHEL FOX COHP 450 In hospitalized patients, does the placement of an IV catheter in the antecubital fossa compared to other peripheral sites effect IV dwell
More informationRESPONSE TO THE LANGUAGE EQUALITY AND ACQUISITION FOR DEAF KIDS (LEAD K) TASK FORCE REPORT
REPORT TO THE HOUSE AND SENATE COMMITTEES ON EDUCATION AND HEALTH AND SENATE COMMITTEES ON HEALTH AND WELFARE OF THE LOUISIANA LEGISLATURE RESPONSE TO THE LANGUAGE EQUALITY AND ACQUISITION FOR DEAF KIDS
More informationQuantitative Research Methods and Tools
Quantitative Research Methods and Tools Fraser Health Authority, 2011 The Fraser Health Authority ( FH ) authorizes the use, reproduction and/or modification of this publication for purposes other than
More informationChapter 11: Experiments and Observational Studies p 318
Chapter 11: Experiments and Observational Studies p 318 Observation vs Experiment An observational study observes individuals and measures variables of interest but does not attempt to influence the response.
More informationobservational studies Descriptive studies
form one stage within this broader sequence, which begins with laboratory studies using animal models, thence to human testing: Phase I: The new drug or treatment is tested in a small group of people for
More informationSetting The setting was primary care. The economic study was carried out in the UK and the USA.
Validation of venous leg ulcer guidelines in the United States and United Kingdom McGuckin M, Waterman R, Brooks J, Cherry G, Porten L, Hurley S, Kerstein M D Record Status This is a critical abstract
More informationConcurrent use of alcohol interactive medications and alcohol in older adults: a systematic review of prevalence and associated adverse outcomes
Concurrent use of alcohol interactive medications and alcohol in older adults: a systematic review of prevalence and associated adverse outcomes Alice Holton Royal College of Surgeons in Ireland 21 September
More informationSTI Treatment Guidelines. Teodora Wi. Training Course in Sexual and Reproductive Health Research
Teodora Wi Geneva, 28 August 2017 STI Treatment Guidelines Teodora Wi Training Course in Sexual and Reproductive Health Research 2017 Twitter @HRPresearch 1 STI treatment guidelines Neisseria gonorrhoeae
More informationRESEARCH. Katrina Wilcox Hagberg, 1 Hozefa A Divan, 2 Rebecca Persson, 1 J Curtis Nickel, 3 Susan S Jick 1. open access
open access Risk of erectile dysfunction associated with use of 5-α reductase inhibitors for benign prostatic hyperplasia or alopecia: population based studies using the Clinical Practice Research Datalink
More informationSeborrheic dermatitis. What is SEBORRHEIC DERMATITIS? This is a common condition which affects 1-3 % of individuals.
750 West Broadway Suite 905 - Vancouver BC V5Z 1H8 Phone: 604.283.9299 Fax: 604.648.9003 Email: vancouveroffice@donovanmedical.com Web: www.donovanmedical.com Seborrheic dermatitis What is SEBORRHEIC DERMATITIS?
More informationSupported by Australian Aid, AusAID
Supported by Australian Aid, AusAID Contents Unit scenario 1 Papua New Guinea: a country profile 2-4 HIV and AIDS 5-6 Responding to HIV and AIDS in PNG 7-8 Nutrition, child and maternal health 9-10 Responding
More informationClinical Research Scientific Writing. K. A. Koram NMIMR
Clinical Research Scientific Writing K. A. Koram NMIMR Clinical Research Branch of medical science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment
More informationEVIDENCE BASED PRACTICE????
In the Name of God Sakineh Hajebrahimi Professor of Urology Department Iranian Center of EBM for Excellence, Tabriz, Iran EVIDENCE BASED PRACTICE???? INTRODUCTORY LECTURE: OBJECTIVES 1. What 2. How What
More informationManagement of patients with should not use past or present history of solid cancer
Practical management of patients receiving abatacept 1 Management of patients with should not use past or present history of solid Evidence-based Medicine Official Recommendations Expert opinion Steps
More informationFirst author. Title: Journal
First author Title: Journal Year: Volume: Issue: First page: Last Page: 1. Type of study Controlled trial without randomization Section B Observational cohort study Section B 2. Type of report Full paper
More informationOpioid use in COPD: balancing benefits and harms. St. Michael s Hospital, University of Toronto
Opioid use in COPD: balancing benefits and harms Nicholas Vozoris MHSc, MD, FRCPC Assistant Professor St. Michael s Hospital, University of Toronto Conflicts of interest None None of my own drug safety
More informationAzathioprine treatment for respiratory conditions. Information for patients Respiratory Medicine - Asthma
Azathioprine treatment for respiratory conditions Information for patients Respiratory Medicine - Asthma What is azathioprine? Azathioprine (also known as Imuran) is a treatment for the immune system.
More informationEpidemiology: Overview of Key Concepts and Study Design. Polly Marchbanks
Epidemiology: Overview of Key Concepts and Study Design Polly Marchbanks Lecture Outline (1) Key epidemiologic concepts - Definition - What epi is not - What epi is - Process of epi research Lecture Outline
More informationCost-Motivated Treatment Changes in Commercial Claims:
Cost-Motivated Treatment Changes in Commercial Claims: Implications for Non- Medical Switching August 2017 THE MORAN COMPANY 1 Cost-Motivated Treatment Changes in Commercial Claims: Implications for Non-Medical
More informationClinical Evidence. A BMJ database of the very best evidence for effective health care
Clinical Evidence A BMJ database of the very best evidence for effective health care Myleen Oosthuizen Academic Information Service School for Health Sciences What is Clinical Evidence? An international
More informationFrequently Asked Questions About Hair Transplantation?
Frequently Asked Questions About Hair Transplantation? The philosophy of hair transplant is hair follicles (resistant) are plucked from the side or back areas of the head and embedded on to the bald areas.
More informationISPOR Good Research Practices for Retrospective Database Analysis Task Force
ISPOR Good Research Practices for Retrospective Database Analysis Task Force II. GOOD RESEARCH PRACTICES FOR COMPARATIVE EFFECTIVENESS RESEARCH: APPROACHES TO MITIGATE BIAS AND CONFOUNDING IN THE DESIGN
More informationMY FITNESS PAL USER GUIDE
MY FITNESS PAL USER GUIDE DIET PROFILE To help personalize your fitness goals, enter the following: Current weight Goal weight Height Gender Date of birth You also enter your normal daily activity options
More informationUSDA Nutrition Evidence Library: Systematic Review Methodology
USDA Nutrition Evidence Library: Systematic Review Methodology Julie E. Obbagy, PhD, RD USDA Center for Nutrition Policy & Promotion Meeting #2 October 17, 2016 The National Academies of Sciences, Engineering,
More informationObservational Medical Studies. HRP 261 1/13/ am
Observational Medical Studies HRP 261 1/13/03 10-11 11 am To Drink or Not to Drink? Volume 348:163-164 January 9, 2003 Ira J. Goldberg, M.D. A number of epidemiologic studies have found an association
More informationTHIS TALK STATINS REDUCE: Immortal time bias Immeasurable time bias Time-window bias TIME-RELATED BIASES IN PHARMACOEPIDEMIOLOGY
TIME-RELATED BIASES IN PHARMACOEPIDEMIOLOGY Samy Suissa McGill University and Jewish General Hospital Montreal, Canada ISPE mid-year meeting, Miami April 22, 2012 STATINS REDUCE: JAMA 2000: Fracture rate
More informationFarmers Market Voucher Program. A Community & Patient Engagement success story December 2, 2014
Farmers Market Voucher Program A Community & Patient Engagement success story December 2, 2014 Brockton Farmers Market 2014 Prescription for Healthy Eating Modern research has shown that a healthy diet
More informationGene Expression and Mutation
Gene Expression and Mutation GENE EXPRESSION: There are hormonal and environmental factors that may cause the expression of some genetic information. Some examples are: 1. The two- colour pattern of some
More informationEBM in action: "Does ovulation induction increase the risk of ovarian cancer?"
Middle East Fertility Society Journal Vol. 11, No. 2, 2006 Copyright Middle East Fertility Society EVIDENCE-BASED MEDICINE CORNER EBM in action: "Does ovulation induction increase the risk of ovarian cancer?"
More informationAnatomy of Medical Studies: Part I. Emily D Agostino Epidemiology and Biostatistics CUNY School of Public Health at Hunter College
Anatomy of Medical Studies: Part I!! Emily D Agostino Epidemiology and Biostatistics CUNY School of Public Health at Hunter College I. Standard format of a Medical Study Abstract (quick overview: what
More informationRisk Study. Section for Clinical Epidemiology and Biostatistics. Definition
Risk Study Section for Clinical Epidemiology and Biostatistics What is Risk? Definition The probability of some untoward event The likelihood that people who are exposed to certain factors (risk factors)
More informationCRITICAL APPRAISAL AP DR JEMAIMA CHE HAMZAH MD (UKM) MS (OFTAL) UKM PHD (UK) DEPARTMENT OF OPHTHALMOLOGY UKM MEDICAL CENTRE
CRITICAL APPRAISAL AP DR JEMAIMA CHE HAMZAH MD (UKM) MS (OFTAL) UKM PHD (UK) DEPARTMENT OF OPHTHALMOLOGY UKM MEDICAL CENTRE MINGGU PENYELIDIKAN PERUBATAN & KESIHATAN PPUKM Lecture content Introduction
More informationRisk Ratio and Odds Ratio
Risk Ratio and Odds Ratio Risk and Odds Risk is a probability as calculated from one outcome probability = ALL possible outcomes Odds is opposed to probability, and is calculated from one outcome Odds
More informationTransfusion triggers in acute coronary syndromes: The MINT trial
Transfusion triggers in acute coronary syndromes: The MINT trial Paul Hébert, MD MHSc(Epid) Physician-in-Chief, CHUM Professor, University of Montreal Objectives Review evidence on transfusion triggers
More informationSensitivity and Positive Predictive Value of the Measles Surveillance System In Uganda,
Public Health Fellowship Program Field Epidemiology Track Sensitivity and Positive Predictive Value of the Measles Surveillance System In Uganda, 2012-2015 Dr.Fred Nsubuga, MBChB, MPH Fellow, Cohort 2015
More informationGLOSSARY of research terms
GLOSSARY of research terms SETTING PRIORITIES FOR VITILIGO RESEARCH - WORKSHOP Thursday 25 th March 2010 Types of studies Case Series: A study reporting on a consecutive collection of patients, treated
More informationHBV-2 Group: neonates born to HBsAg+ and HBeAg+ mothers who received a 4-dose vaccination regimen (Part of
The study listed may include approved and non-approved uses, formulations or treatment regimens. The results reported in any single study may not reflect the overall results obtained on studies of a product.
More informationSystematic review ALHIV: Disclosure, adherence and retention in care
WHO/HIV/2013.129 World Health Organization 2013 HIV and adolescents: guidance for HIV testing and counselling and care for adolescents living with HIV ANNEX 4: Systematic review ALHIV: Disclosure, adherence
More informationComprehensive Outreach Education Certificate Program. & Health Modules. Spring 2014
Comprehensive Outreach Education Certificate Program & Health Modules Community Health Education Center Lowell Community Health Center 161 Jackson Street Lowell, MA 01852 Tel: 978-452-0003 Fax: 978-221-6215
More informationConceptual Framework for Follow-up Study of Thimerosalcontaining. Neurologic Developmental Disorders (NDDs) Paul A. Stehr-Green
Conceptual Framework for Follow-up Study of Thimerosalcontaining Vaccines and Neurologic Developmental Disorders (NDDs) Paul A. Stehr-Green Thanks to all CDC/ATSDR contributors ESPECIALLY: Bill Thompson
More informationEvidence-Based Review Process to Link Dietary Factors with Chronic Disease Case Study: Cardiovascular Disease and n- 3 Fatty Acids
Evidence-Based Review Process to Link Dietary Factors with Chronic Disease Case Study: Cardiovascular Disease and n- 3 Fatty Acids Alice H. Lichtenstein, D.Sc. Gershoff Professor of Nutrition Science and
More informationClinic and Community-Based Intervention Programs: Impact on Gestational Weight Gain
Clinic and Community-Based Intervention Programs: Impact on Gestational Weight Gain Christine M. Olson, PhD Professor June 5, 2008 Introduction o 33 to 44% of US women gain within the IOM recommendations;
More informationPatterns and Cost of Health Care Transitions to Adult Care among Youth with Chronic Conditions in Ontario: A Population Based Cohort Study
Patterns and Cost of Health Care Transitions to Adult Care among Youth with Chronic Conditions in Ontario: A Population Based Cohort Study Eyal Cohen, MD, MSc; Sima Gandhi, MSc; Charlotte Moore, MD; Alene
More informationThe Intersection of Post-Traumatic Stress and Substance Use Disorders. Implications for an emerging integrated treatment approach
The Intersection of Post-Traumatic Stress and Substance Use Disorders Implications for an emerging integrated treatment approach Christal L. Badour, PhD Assistant Professor Department of Psychology Overview
More information5-Part Series on Alport Syndrome by Dr. Clifford Kashtan
5-Part Series on Alport Syndrome by Dr. Clifford Kashtan Dr. Clifford Kashtan is the director of the Alport Syndrome Treatments and Outcomes Registry (ASTOR) and a member of the ASF Medical Advisory Committee.
More informationClinical Evidence: Asking the Question and Understanding the Answer. Keeping Up to Date. Keeping Up to Date
Clinical Evidence: Asking the Question and Understanding the Answer Keeping Up to Date 5,000? per day 1,500 per day 95 per day Keeping Up to Date 5,000? per day 1,500 per day 95 per day 1 Bias Bias refers
More informationCOASTING NEWS. SPRING 2007
COASTING NEWS. SPRING 2007 Gymfinity The fourth Annual GYMFINITY Activity needs to be cancelled for this Sunday, March 11, 2007. Unfortunately, Gymfinity had a scheduling conflict, and the COAST staff
More information