Strategic Fund Medicine List / Lista de Medicamentos del Fondo Estratégico 1 Updated September

Transcription

1 1 Updated September International Nonproprietary Name (INN) / Denominación Común Internacional (DCI) ANALGESICS Opioid analgesics Strength / Concentracion Presentation / Forma Farmacéutica Codeine 15mg; 30mg (phosphate) Morphine Morphine Morphine 10mg/ml (sulfate or hydrochloride) in 1ml ampoule 10mg/5ml (sulfate or hydrochloride) 10mg; 30mg; 60mg (sulfate) Oral Solution (prolonged release) Indication(s)/ Indicacion(es) Analgesic Analgesic; Anaesthetic; Preoperative and short procedures Analgesic; Palliative care Analgesic; Palliative care ANTI-INFECTIVE MEDICINES Antibacterial Amoxicillin + Clavulanic acid 500mg + 125mg Antibacterial Azithromycin 200mg/5ml Oral Solution Azithromycin (for Trachoma treatment) 250mg; 500mg (anhydrous) Antibacterial Benzathine benzylpenicillin Benzylpenicillin Procaine benzylpenicillin 900 mg benzylpenicillin (=1.2 million IU) in 5mL vial; 1.44 g benzylpenicillin (=2.4 million IU) in 5mL vial 600 mg (=1 million IU) (sodium or potassium salt) in vial; 3 g (=5 million IU) (sodium or potassium salt) in vial 1 g (=1 million IU); 3 g (= 3 million IU) in vial Doxycycline 100mg ; Capsule Sulfadiazine 500mg Antibacterial; Syphilis Antibacterial; Syphilis Antibacterial; Syphilis Antibacterial; Malaria prophylaxis and treatment Anti-pneumocystosis; Anti-toxoplasmosis Ref 2 1 The therapeutic indications presented in this list of medicines appear as published in the 20th World Health Organization Model List of Essential Medicines published March The Strategic Fund Medicine List does not seek to replace or complement the WHO the Essential Medicine List or Member States national essential medicine lists. As a result, this list should not be utilized as reference for the development of other essential medicine lists or treatment guidelines. - Las indicaciones terapéuticas se presentan con base en la decimonovena Lista de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en Marzo La Lista de Medicamentos del Fondo Estratégico no supone ninguna complementación o ampliación de la Lista de Medicamentos Esenciales de la OMS o de las listas de medicamentos esenciales nacionales de los Estados Miembros. Consecuenteme nte, esta lista no debería ser utilizada como referencia para la elaboración de listas de medicamentos esenciales o guías de tratamiento. 2 Only used as single dose treatment of genital Chlamydia Trachomatis and of trachoma. - Solamente utilizado en dosis única para el tratamiento de chlamydia trachomatis genital y tracoma.

2 Antileprosy med. Clofazimine 50mg; 100mg Capsule Dapsone 25mg; 50mg; 100mg Leprosy 3 Ofloxacin 400mg Leprosy (second-line) 4 Antituberculosis med. Ethambutol 100mg; 400mg Ethambutol 25mg/ml Oral Solution Isoniazid 50mg/5ml Oral Solution Isoniazid 100mg (dispersable) Isoniazid 300mg Tuberculosis Pyrazinamide 400mg Pyrazinamide 150mg (scored); (dispersible) Pyrazinamide 30mg/ml Oral Solution Rifabutin 150mg Capsule 5 Rifampicin 20mg/ml Oral Solution Rifampicin 150mg; 300 mg ; Capsule Tuberculosis; Leprosy 3 Rifampicin + Isoniazid 75mg + 50mg (dispersable) Rifampicin + Isoniazid 60mg + 30mg (dispersable) Rifampicin + Isoniazid 150mg + 75mg ; 300mg + 150mg; 60mg + 60mg; 150mg + 150mg Rifampicin + Isoniazid + Ethambutol 150mg + 75mg + 275mg Tuberculosis Rifampicin + Isoniazid + Pyrazinamide 75mg + 50mg + 150mg (dispersable) Rifampicin + Isoniazid + Pyrazinamide 60mg + 30mg + 150mg (dispersable) Rifampicin + Isoniazid + Pyrazinamide 150mg + 75mg + 400mg; 150mg + 150mg + 500mg Rifampicin + Isoniazid + Pyrazinamide + 150mg + 75mg + 400mg + Ethambutol 275mg Rifapentine 150mg 6 Antiberculosis med. 2 nd line Amikacin 1g (sulfate) in vial Multidrug-resistant tuberculosis Bedaquiline 100mg (MDR/TB) 7 3 Medicines used in the treatment of leprosy should never be used except in combination. - Los medicamentos para el tratamiento de lepra siempre deben ser utilizados en combinación. 4 To be used in combination with rifampicin as a second-line therapy for leprosy treatment. - Para ser utilizado en combinación con rifampicina para el tratamiento de segunda línea de la lepra. 5 For use in patient with HIV receiving protease inhibitors. - Para el uso en pacientes con VIH que reciben inhibidores de proteasa. 6 For treatment of latent tuberculosis infection only Para el tratamiento de la tuberculosis latente unicamente. 7 Procurement of this medicine through the Strategic Fund should be limited for use according to WHO recommended M/XDR-TB regimen in patients for whom there are few or no treatments available. Patients receiving this medicine should be monitored for potential adverse events or related toxicities through national pharmacovigilance programs and data from the WHO Programme for International Drug Monitoring (UPPSALA). - La adquisición de este medicamento a través del Fondo Estratégico debe ser limitada para el uso en pacientes con tuberculosis multi y extensivamente resistente (M-XDR TB) en que hay pocos o ningún tratamiento disponibles y usado según el regimen recomendado por la OMS para M-XDR-TB. Los pacientes que reciben este medicamento deben ser controlados para posibles eventos Page 2 of 12

3 Capreomycin 0.5g; 1g (sulfate) in vial Clofazimine 50mg; 100mg Capsule Cycloserine 250mg Capsule Cycloserine 250mg Delamanid 50mg Ethionamide 125mg ; 250mg Kanamycin 1g (sulfate) in vial Multidrug-resistant tuberculosis Levofloxacin 250mg ; 500mg; 750mg (MDR/TB) Linezolid 600mg 7 Linezolid 100mg/5ml Oral Solution Moxifloxacin 400mg Protionamide 250mg 8 P-aminosalicylic acid 4g in sachet Granule P-aminosalicylate sodium (PAS sodium) 100g (60% w/w) Granules Streptomycin 1g ( sulfate) in vial Terizidone 250mg Capsule 9 Antifungal Amphotericin B 50mg ( sodium deoxycholate or liposomal complex) in vial Antivirals Antiretrovirals Abacavir 60mg (dispersible, scored) Abacavir 300mg Abacavir + Lamivudine 60mg + 30mg; 120mg + 60mg (dispersible, scored) Antifungal; Anti-Lesihmaniasis Abacavir + Lamivudine 600mg + 300mg Atazanavir 100mg Capsule HIV/AIDS Atazanavir 300mg Capsule Atazanavir + Ritonavir 300mg + 100mg Darunavir 75mg; 150mg; 400mg; 600mg; 800mg 10 Dolutegravir 50mg Dolutegravir + Lamivudine + Tenofovir 50mg + 300mg + 300mg Efavirenz 200mg (scored) Efavirenz 600mg Emtricitabine 200mg Capsule 7 adversos o efectos tóxicos relacionados al medicamento a través de programas nacionales de farmacovigilancia y datos del Programa de la OMS para la Vigilancia Farmacéutica Internacional (UPPSALA). 8 Protionamide may be an alternative to ethionamide. La protionamida puede ser utilizada como alternativa a la etionamida. 9 Terizidone may be an alternative to cycloserine. La terizidona puede ser utilizada como alternativa a la cicloserina. 10 Age restriction > 3 years old. Restricción de edad > 3 años de edad. Page 3 of 12

4 Etravirine 100mg; 200mg 11 Lamivudine 150mg Lamivudine 10mg/ml Oral Solution Lamivudine + Zidovudine 30mg +60mg (dispersible, scored) Lamivudine + Zidovudine 150mg+300mg Lopinavir + Ritonavir 100mg + 25mg; (heat 200mg + 50mg stable) Lopinavir + Ritonavir 40mg + 10mg Oral pellets (heat stable) Lopinavir + Ritonavir 80mg+20mg/ml Oral Solution Nevirapine 200mg Nevirapine 50mg (dispersible, scored) Nevirapine 50mg/5ml (100ml) Oral Solution Ritonavir 25mg (heat stable) Ritonavir 100mg (heat HIV/AIDS stable) Ritonavir 400mg/ 5mL (240ml) Oral solution Raltegravir 25mg; 100mg (chewable) 11 Raltegravir 400mg 11 Tenofovir 300mg Tenofovir 200mg Tenofovir + Emtricitabine 300mg + 200mg Tenofovir + Emtricitabine + Efavirenz 300mg + 200mg + 600mg Tenofovir + Lamivudine 300mg + 300mg Capsule Tenofovir + Lamivudine + Efavirenz 300mg + 300mg + 400mg; 300mg + 300mg + 600mg Zidovudine 300mg Zidovudine 60mg (dispersible, scored) Zidovudine 50mg/5ml (100ml) Oral Solution Zidovudine 10mg/ml in 20ml vial Solution for IV Infusion Zidovudine + Lamivudine + Nevirapine 60mg + 30mg + 50mg (dispersible, scored) Zidovudine + Lamivudine + Nevirapine 300mg + 150mg + 200mg Other Antivirals Acyclovir 250mg ( sodium salt) in vial Herpes Virus 11 Procurement of this medicine through the Strategic Fund should be limited for use as third-line therapy in treatment-experienced HIV adults who failed second-line antiretroviral therapy. It is recommended patients receiving HIV/AIDS regimens including this medicine be monitored for potential adverse events or related toxicities through national pharmacovigilance programs and data from the WHO Programme for International Drug Monitoring (UPPSALA). - La adquisición de este medicamento a través del Fondo Estratégico debe ser limitada para su uso como tratamiento de tercera línea en adultos con VIH tratados previamente que reprobaron la terapia antirretroviral de segunda línea. Se recomienda que los pacientes que reciben regímenes de VIH / SIDA que incluyen este medicamento ser monitorizados para detectar posibles eventos adversos o efectos tóxicos relacionados al medicamento a través de los programas nacionales de farmacovigilancia y los datos del Programa de la OMS para la Vigilancia Farmacéutica Internacional (UPPSALA). Page 4 of 12

5 Acyclovir 200mg Oseltamivir 75mg (phosphate) Capsule Oseltamivir 12mg/ml Oral Solution Anti hepatitis medicines Medicines for Hepatitis B Entecavir 0.05mg/ml Oral Solution Entecavir 0.5mg; 1mg Tenofovir disoproxil fumarate 300mg Medicines for Hepatitis C 13 Daclastavir 30mg; 60mg Dasabuvir 250mg Ledipasvir + Sofosbuvir 90mg + 400mg Ombitasvir + Paritaprevir + Ritonavir 12.5mg + 75mg + 50mg Simeprevir 150mg Capsule Sofosbuvir 400mg Sofosbuvir + Velpatasvir 400mg + 100mg Antiprotozoal medicines Antileishmaniasis medicines Meglumine antimoniate 1.5g/ 5 ml (81 mg/ml) in 5ml ampoule Amphotericin B 50mg (sodium deoxycholate or liposomal complex) in vial Miltefosine 10mg; 50 mg Paromomycin Pentamidine Anti-malarial Amodiaquine 750mg of paromomycin base (sulfate) 300mg (isethionate) 153 mg; 200 mg Solution for Intramuscular Influenza Virus (in compliance with WHO treatement guidelines) Chronic Hepatitis B Chronic Hepatitis C Leishmanaiasis Leishmanaiasis Leishmaniasis 14 Malaria treatment to be used in combination with artesunate for P. falciparum. Artemether 80 mg/ml 1 ml ampoule Oily Severe malaria Artemether + Lumefantrine 20 mg mg Malaria treatment Artesunate 60 mg (anhydrous artesunic acid) Severe malaria 15 Artesunate 50 mg; 200mg Rectal Dosage Form Severe malaria According to the 20th World Health Organization Model List of Essential Medicines published in March 2017, Oseltamivir is indicated for severe illness fue to confirmed or suspected influenza virus infection in critically ill hospitalized patients. - De acuerdo con la vigésima Lista Modelo de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en marzo de 2017 Oseltamivir, el uso del oseltamivir es indicado solo en casos confirmados o sospechados de influenza viral en pacientes hospitalizados y en situación de enfermedad critica. (WHO 20th EML 2017) 13 According to the 20th World Health Organization Model List of Essential Medicines published in March 2017 and based on current evidences, medicines of this class act as direct antiviral medicines and are included as essential medicines for treatment of hepatitis C virus infection. WHO guidelines recommend specific combinations therapies utilizing medicines from different classes. - De acuerdo con la vigésima Lista Modelo de Medicamentos Esenciales de la Organización Mundial de la Salud publicada en marzo de 2017 y basándose en la evidencia actual, los medicamentos en esta categoría funcionan como antivirales de acción directa y se incluyen como medicamentos esenciales para el tratamiento de la infección por el virus de la hepatitis C. Las guías de la OMS recomiendan combinaciones terapéuticas específicas con medicamentos de diferentes clases. (WHO 20th EML 2017) 14 This medicine should be used in accordance to the recommendations outlined in the Leishmaniasis in the Americas: Recommendations for the treatment (2013) guide. - Este medicamento debe utilizarse en acuerdo con las recomendaciones formuladas en la guía Leishmaniasis en las Américas: Recomendaciones para el tratamiento (2013). 15 Product may be co-packaged with 1 ampoule of 5% sodium bicarbonate solution and 1 ampoule of sodium chloride solution. - Producto puede ser presentado en conjunto con 1 ampolla de solución de bicarbonato sódico y 1 ampolla de solución de cloruro de sodio. Page 5 of 12

6 Artesunate + Mefloquine 100 mg + 220mg Malaria treatment Artesunate + Amodiaquine 25 mg mg ; 50 mg mg ; 100 mg mg Malaria treatment Atovaquone + Proguanil mg (adult) Atovaquone + Proguanil mg (pediatric) Malaria prophylaxis and treatment Chloroquine 50 mg (phosphate or sulfate)/5 ml Oral Solution Chloroquine 100 mg; 150 mg (phosphate or sulfate) Malaria prophylaxis and treatment Mefloquine 250 mg Malaria prophylaxis; Malaria treatment to be used in combination with artesunate for P. falciparum Dihydroartemisinina + Piperaquina 40 mg mg Malaria treatment As complement to malaria Primaquine 5mg; 7.5 mg ; 15 mg treatment (for radical cure of (diphosphate) P.vivax and P.ovale and as gametocytocide for P. falciparum) Quinine 300 mg quinine hydrochloride/ml in 2ml Severe malaria ampoule Quinine 300 mg (quinine sulfate or bisulfate) Malaria treatment Sulfadoxine + Pyrimethamine 500 mg + 25 mg Malaria treatment to be used in combination with artesunate for P. falciparum Antipneumocystosis and antitoxoplasmosis medicines Pyrimethamine 25mg Sulfamethoxazole + Trimethoprim 80mg + 16mg/ml in 5ml or Pneumocystis; 10ml ampoule Toxoplasmosis Pentamidine 200mg; 300mg Antitrypanosomal medicines 12.5 mg Benznidazole 50 mg (scored) American Trypanosomiasis 100mg Nifurtimox 120mg African Trypanosomiasis (2nd stage); American Trypanosomiasis Anthelminthics Intestinal anthelminthics Albendazole 400mg (chewable) Intestinal Anthelminthic; Anti- Filarial Ivermectin 3mg (scored) Strongyloidiasis Mebendazole 500mg (chewable) Intestinal anthelminthic Niclosamide 500mg Intestinal anthelminthic (for use when praziquantel fails) (chewable) Anticestodes Page 6 of 12

7 Praziquantel 150mg; 600mg Intestinal anthelminthic; Praziquantel 600mg Antischistosomals and Antitrematode Medicines Triclabendazole 250mg Antifilarials Dietylcarbamazine 50mg; 100mg (dihydrogen citrate) ANTINEOPLASTIC, IMMUNOSUPPRESSIVES AND MED. USED IN PALLIATIVE CARE Immunosuppressive Agents Azathioprine 100mg (sodium salt) in vial Antischistosomal; Antitrematode; Anticestode Antitischistosomal; Antitrematode Filariasis Immunosuppressive Azathioprine 50mg DMARD Cyclosporine 25mg Capsule Cyclosporine 50mg/ml in 1ml ampoule Mycophenolate Mofetil Tacrolimus Cytotoxic medicines Asparaginase Bleomycin 250 mg Capsules 500 mg s Capsules 0.5, 1, 5 mg (immediate release) 10,000 IU in vial 15mg (sulfate) in vial Immunosuppressive Prophylaxis of organ rejection in adult patients receiving allogeneic renal transplants Prophylaxis of organ rejection in adult patients receiving allogeneic renal or hepatic transplants Cytotoxic Agent Calcium folinate 3mg/ml in 10ml ampoule Calcium folinate 15mg Adjuvant Medicine Carboplatin 150mg; 450mg Cytotoxic and Adjuvant Medicine Chlorambucil 2mg Cytotoxic Agent Cisplatin 10mg; 50mg Cytotoxic and Adjuvant Medicine Cyclophosphamide 500mg in vial Cytotoxic Agent Cyclophosphamide 25mg Cytarabine 100mg in vial Dacarbazine 100mg in vial Dactinomycin 500µg in vial Cytotoxic Agent Daunorubicin 50mg in vial Docetaxel 20mg/ml Cytotoxic and Adjuvant Medicine 10mg; 50mg Doxorubicin in vial Cytotoxic Agent Etoposide 100mg Capsule Etoposide 20mg/ml in 5ml ampoule Fluorouracil 50mg/ml in ampoule Cytotoxic and Adjuvant Medicine Page 7 of 12

8 Ifosfamide 1g vial Cytotoxic and Adjuvant Medicine Mercaptopurine 50mg Cytotoxic Agent Mesna (2-mercaptoethane sulfonate 100mg/ml in 4ml and 10ml sodium) ampoules Adjuvant Medicine Methotrexate 50mg (sodium salt) in vial Cytotoxic Agent Methotrexate 2.5mg (sodium salt) Cytotoxic Agent; DMARD Paclitaxel 6mg/ml Cytotoxic and Adjuvant Medicine Procarbazine 50mg Capsule Cytotoxic Agent Tamoxifen 10mg; 20mg (citrate) Hormone/Anti-Hormone Trastuzumab 150 & 440 mg HER2+ early breast cancer Vinblastine 10mg (sulfate) in vial Vincristine 1mg; 5mg (sulfate) in vial Cytotoxic Agent BLOOD PRODUCTS AND PLASMA SUBSTITUTES Plasma fractions for specific use Human normal immunoglobulin 16% protein solution for Intramuscular Administration Human normal immunoglobulin Coagulation factor VIII Coagulation factor IX 5% protein solution; 10% protein solution 500UI/vial 500UI/vial; 1000UI/vial for Intravenous Administration Plasma fractions for specific use Blood coagulation factors IMMUNOBIOLOGICS Sera and immunoglobulins Prevention of newborn hemolytic anti-d immunoglobulin (human) illnesses; 250µg in single-dose vial Rh negative populations (prophylaxis) CARDIOVASCULAR MEDICINES Antihypertensive medicines Amlodipine 5mg (maleate, mesylate or besylate) Antihypertensive Bisoprolol 1.25mg; 5mg Antihypertensive; Antianginal; Carvedilol 3.125mg; 6.25mg; 12.5mg; Antiarrhythmic; Medicines used in 25mg; 50mg heart failure Chlorthalidone 12.5mh; 25mg Hypertension in adults Enalapril 2.5mg; 5mg (hydrogen Antihypertensive; Medicines used maleate) in heart failure Hydralazine 20mg in ampoule Hypertension Indicated for primary immune deficiency. - Indicado para deficiencia inmune primaria. 17 Indicated for primary immune deficiency and Kawasaki disease. - Indicado para deficiencia inmune primaria y enfermedad de Kawasaki. 18 Metoprolol and carvedilol as alternatives. - Alternativos: metoprolol y carvedilol. Page 8 of 12

9 Hydralazine 25mg; 50mg Hypertension Hydrochlorothiazide 12.5mg; 25mg Antihypertensive; Medicines used in heart failure; Diuretics Losartan 25mg; 50mg; 100mg s Hypertension in adults 19 Methyldopa 250 mg Antihypertensive 20 Metoprolol 100mg Sodium nitroprusside Surfactant (Surfactante pulmonar exogeno) Antiarrhythmic medicines Amiodarone 50mg in ampoule 25mg/ml; 80mg/ml 100 mg; 200 mg; 400 mg 50 mg / ml in 3 ml ampoule 250 micrograms/ml in 2 ml ampoule Infusion Suspension for Intratracheal Instillation Antihypertensive; Antianginal; Antiarrhythmic; Medicines used in heart failure Hypertension Neonatal care Antiarrythmic Antiarrythmic Medicines used in heart failure Digoxin 62.5 micrograms; 250 micrograms 50 micrograms/ml Oral Solution Lidocaine 20 mg /ml in 5 ml ampoule Antiarrythmic Verapamil 2.5 mg /ml in 2 ml ampoule Antiarrythmic 40 mg; 80 mg Antianginal medicines Diuretics Spironolactone 25mg Diuretic Antianginal medicines Glyceryl trinitrate 500µg (sublingual) Angina Antithrombotic medicines Clopidogrel 75 mg Prevention of atherothrombotic events in adults with non-st segment elevation acute coronary syndrome Streptokinase 1.5million IU in vial Thrombosis Lipid-lowering agents Simvastatin 5mg; 10mg; 20mg; 40mg Lipid-Lowering Agents 19 Losartan can be used as an alternative for treatment of adults with hypertension for those patients in whom ACEi are indicated but not tolerated, specifically due to the presence of adverse events (mainly cough); including the sub-population of hypertensive patients associated with type II diabetes with proteinuria. - Losartan puede ser utilizado como una alternativa para el tratamiento de hipertensión en adultos, para aquellos pacientes en los cuales los IECA están indicados pero no se toleran, específicamente debido a la presencia de eventos adversos (principalmente la tos); incluyendo la sub-población de pacientes hipertensos con asociación de diabetes tipo II con proteinuria. 20 Methyldopa is listed for use only in the management of pregnancy induced hypertension. Its use in the treatment of essential hypertension is not recommended in view of the evidence of greater efficacy and safety of other medicines (WHO 20 th EML). - Metildopa se lista sólo para su uso en el manejo de la hipertensión inducida por el embarazo. Su uso en el tratamiento de la hipertensión esencial no se recomienda basado en la evidencia de una mayor eficacia y seguridad de otros medicamentos (20 a LME OMS). Page 9 of 12

10 DIAGNOSTIC AGENTS Radiocontrast media Amidotrizoate 140mg to 420mg iodine (sodium or Meglumine Radiocontrast Media salt)/ml in 20ml ampoule HORMONES, ENDOCRINE MED. Contraceptives Oral hormonal contraceptives Ethinylestradiol + levonorgestrel 30µg + 150µg Ethinylestradiol + norethisterone 35µg + 1.0mg Contraception Levonorgestrel 30µg; 750µg (pack of two); 1.5mg Contraception Injectable hormonal contraceptives Medroxyprogesterone acetate 150mg/ml in 1ml vial. Depot Medroxyprogesterone acetate + Contraception 25mg + 5mg estradiol cypionate Norethisterone enantate 200mg/ml in 1ml ampoule Oily Contraception Insulins and other antidiabetic agents Insulin soluble 40 IU/ml; 100 IU/ml in 10ml vial Intermediate-acting insulin 40 IU/ml; 100 IU/ml in 10ml vial (coumpound insulin zinc suspension or isophane Diabetes insulin) Glibenclamide 2.5mg; 5mg Metformin 500mg MEDICINES AFFECTING THE BLOOD Antianaemia medicines Recombinant Human Erythropoietin 2,000-5,000 UI/ml Recombinant Human Erythropoietin 20,000-50,000 UI/ml Anemia Medicines affecting coagulation Warfarin 0.5mg; 1mg; 2mg; 5mg (sodium salt) Anticoagulant ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS Dexamethasone 4mg/ml in 1ml ampoule (disodium phosphate salt) Antiemetic; Anti-allergic /Anaphylaxis; Cytotoxic; Palliative care Dexamethasone 2 mg Palliative care 100mg (sodium succinate) in Anaphylaxis; Hydrocortisone vial Cytotoxic MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE INHIBITORS Vecuronium 10mg (bromide) in vial OXYTOCICS AND ANTIOXYTOCICS Oxytocics Oxytocin 10 UI in 1 ml ampoule Ergometrine 200µg (hydrogen maleate) in 1ml ampoule Mifepristone Misoprostol 200mg - 200µg s Misoprostol 200µg ANTICONVULSANT AND ANTIEPILEPTIC Phenytoin 25mg; 50mg; 100mg (sodium salt) Capsule Muscle Relaxant Oxytocic Oxytocic Anticonvulsant; Page 10 of 12

11 Phenytoin 50mg/ml (sodium salt) in 5ml vial Phenytoin 25mg/5 ml; 30mg/5 ml Oral Solution Phenobarbital 50mg/ml in 5ml vial (sodium salt) Phenobarbital 15mg/5 ml Oral Solution Phenobarbital 15mg; 100mg Carbamazepine 100mg/5 ml Oral Solution Carbamazepine 100mg; 200mg (chewable) Carbamazepine 100mg; 200mg (scored) Diazepam Magnesium sulfate 5mg/ml in 0.5ml; 2ml; 4ml tubes 500mg/ml in 2ml or 10ml ampoule 200mg; 500mg (sodium valproate) Gel or; Rectal solution (entericcoated) Valproic acid 100mg (crushable) 200mg/5ml Oral solution 100mg/ml in 4ml ampoule; 100mg/ ml in 10ml ampoule PSYCHOTHERAPEUTIC MEDICINES Chlorpromazine 25mg /ml in 2ml ampoule. Chlorpromazine 25mg /5 ml Oral Solution Chlorpromazine 100mg Fluphenazine 25mg (decanoate or enantate) in 1ml ampoule Haloperidol 5mg in 1ml ampoule Haloperidol 2mg; 5mg Antiepileptic Anticonvulsant; Antiepileptic Anticonvulsant; Antiepileptic Medicine used in bipolar disorders Anticonvulsant; Antiepileptic Psychotic Disorders Medicines used in mood disorders Amitriptyline 10mg; 25mg Palliative Care; Depressive Disorders Fluoxetine 20mg Capsule Palliative Care; Fluoxetine 20mg Depressive Disorders Medicines used in bipolar disorders Lithium carbonate 300mg Capsule Lithium carbonate 300mg Bipolar Disorder Medicines used for disorders due to psychoactive substance use Nicotine replacement therapy (gums) 2mg; 4mg (as polacrilex) Gums Nicotine replacement therapy (patch) 5mg to 30mg/16 h; Transdermal Tobacco cessation 7mg to 21mg/24h patch Treatment with 10mg should be utilized only in palliative care. - Tratamiento con 10mg solo debería ser utilizado en cuidados paliativos. Page 11 of 12

12 ANTIPARKINSONISM MEDICINES Biperiden 5mg (lactate) in 1ml ampoule Biperiden 2mg GASTROINTESTINAL MEDICINES Antiulcer Medicines Omeprazole oral 20 mg; 40 mg liquid in Sachets 10 mg; 20 mg; 40 mg Solid oral dosage form 25 mg/ml (as hydrochloride) in 2-ml ampoule Ranitidine 150 mg (as hydrochloride) 75 mg/5 ml (as hydrochloride) Oral Solution MEDICINES ACTING ON THE RESPIRATORY TRACT Antiasthmatic and medicines for chronic obstructive pulmonary disease Beclometasone Ipratropium bromide Salbutamol OTHERS 50 micrograms (dipropionate) per dose; 100 micrograms (dipropionate) per dose (as CFC free forms) 20 micrograms/metered dose 100 micrograms (as sulfate) per dose 50 micrograms (as sulfate)/ml 100 micrograms (as sulfate) per dose 5 mg (as sulfate)/ml Inhalation (aerosol) Inhalation (aerosol) Inhalation (aerosol) in 5 ml ampoule Metered dose inhaler (aerosol) Respirator solution for use in nebulizers Calcium gluconate 100mg/ml in 10ml ampoule Parkinson s Disease Antiulcer medicines Antiasthmatic Medicines used for chronic obstructive pulmonary disease (COPD) Specific Use Antidotes and Others Substances Used in Poisoning; Vitamins and Minerals Page 12 of 12