2. Has the child had a physician s diagnosis of atopic dermatitis or atopic eczema ever?

Transcription

1 Online Supplement 2: Letter questionnaire RISK FACTORS FOR THE DEVELOPMENT OF ASTHMA 1. Have the child s parents had a history of asthma ever? 2. Has the child had a physician s diagnosis of atopic dermatitis or atopic eczema ever? 3. Has the child ever had wheezing apart from colds? 4. Has the child ever had allergy to pets? 4b. if YES, where diagnosed: 5. Has the child ever had allergy to pollen? 5b. if YES, where diagnosed: 6. Has the child ever had allergy to house dust mite? 6b. if YES, where diagnosed: 7. Has a physician ever told you that the child has food allergies? 7b. if YES, which allergies: 7c. if YES, where diagnosed: 8. Was blood drawn for any of your child s allergy tests ever? 8b. if YES where

2 QUESTIONS 9-24: During the past 12 months (after the study hospitalization) 9. Has the child had an expiratory wheezing episode or exacerbation of asthma? 9b. if YES, number of episodes 10. Has the child had a tight cough episode excluding the wheezing episodes mentioned above? 10b. if YES, number of episodes 11. Has the child benefitted from a bronchodilator (Airomir, Bricanyl, Serevent, Ventoline) during a wheezing episode or exacerbation of asthma? 11b. if YES, number of episodes 11c. if YES, the used product 1)Airomir 2)Bricanyl 3)Serevent 4)Ventoline 12. Has the child benefitted from a bronchodilator (Airomir, Bricanyl, Serevent, Ventoline) during a tight cough episode excluding the wheezing episodes mentioned above? 12b. if YES, number of episodes 12c. if YES, the used the product 1)Airomir 2)Bricanyl 3)Serevent 4)Ventoline 13. Has the child had a wheezing episode or exacerbation of asthma that lasted more than a day and affected your child s sleep? 13b. if YES, number of episodes 14. Has the child had a tight cough episode that lasted more than a day and affected your child s sleep excluding the wheezing episodes mentioned above? 14b. if YES, number of episodes 15. Has the child required bronchodilators more than 2 days per week for a period of over 4 weeks for continuous wheeze or tight cough or asthma symptoms?

3 16. Has the child had an acute wheezing or tight cough or exacerbations of asthma requiring systemic (p.o., i.v., i.m.) corticosteroids (e.g. Prednisolon, Prednison, Dexametason, Oradexon)? 16b. if YES, number of episodes 17. Has the child had at least 2 episodes of acute wheezing or tight cough or exacerbations of asthma requiring systemic corticosteroids within 6 months? 18. Has the child had unscheduled clinic/er visits for wheezing or tight cough or asthma excluding hospitalizations? 18b. if YES, number of episodes 18c. if YES, which clinics or ERs have you visited? 19. Has the child had acute wheezing or tight cough or exacerbations of asthma that needed hospitalization? 19b. if YES, number of episodes 19c. if YES, in which hospitals? 20. In the 12 months, was your child prescribed a long-term regular controller medication for recurrent wheezing or prolonged cough or asthma? 20b. if YES, when was it initiated? mm/yyyy 20c. if YES, where was it initiated? 20d. if YES, how many months used? 20e. if YES, any controller medication during the past month? 21. In the past year, did your child s physician call your child s breathing problem asthma? 21b. if YES, when for the first time? mm/yyyy 21c. if YES, where?

4 22. For the past 12 months, has the child had itching rash (atopic eczema or dermatitis)? 22b. if YES, has the eczema been on the bend of the elbows, on the bend of the knees, front of the ankles, buttocks, neck or around eyes or ears? 23. Has the child had allergic rhinitis or allergic eye symptoms (rhinitis or eye symptoms from pollen, dust mire or animals)? 23b. if YES, when for the first time? mm/yyyy 23c. if YES, what was the probable cause? 24. Does the child require any other regular (more than 1 month) medication than the ones already mentioned in this questionnaire? 24b. if YES, what medication? 24c. if YES, when did it begin? 24d. if YES, how long time was it used? mm 24e. if YES, where was it prescribed? QUESTIONS 25-28: before the past 12 months (before the study hospitalization) 25. Has the child had wheezing or bronchiolitis before the past year? 25b. if YES, when for the first time? mm/yyyy 26. Has the child had atopic eczema or dermatitis before the past year? 26b. if YES, when did it begin? mm/yyyy 27. Has the child had allergic rhinitis before the past year? 27b. if YES, when did it begin? mm/yyyy

5 28. Has the child had some other chronic disease? 28b. if YES, what? BACKGROUND QUESTIONS 29. Where do you live? 1) town 2) rural population center 3) dispersed settlement 30. Does the child have contacts with animals weekly? 30b. if YES, with what animals? 31. Do you currently have pets? 31b. if YES, which pets? 32. Does the child visit places were animals are currently kept? 32b. if YES, where? 1) cowhouse 2) piggery 3) horse stable 4) something else, what? 32c. if YES, how often does the child visit these places? 1) every day or most of the days 2) 1-2 times /wk 3) 1-2 times /mo 4) less frequently

6 33. Does anyone smoke at your house? 33b. if YES, who? 1) father 2) mother 3) nanny 33c. if YES, does the smoking occur 1) usually inside 2) usually outside 3) always outside 34. What is the place for child's daycare? 1) home 2) private childminder's house 3) day care center 4) something else 35. How did the time split between daycare forms during the past 12 months? 35a. How many months at home? mo 35b. How many months with private childminder? mo 35c. How many months in day care center? mo 36. How many children under 18 years of age live in the same household at the moment? 37. How many years has the child's mother studied after compulsory school (9 grades in Finland)? QUESTIONS ABOUT THE USE OF VITAMIN D 37b. Total duration of breastfeeding? mo 38. Has the vitamin D been given according to the instructions of the child health center? 39. What is the name of the vitamin D product mainly used? 39b. If you do not remember the name of the product, how was it used? 1) 3-5 drops/day 2) drops/day 40. Did you forget to give the vitamin D 1) very little 2) reasonably often 3) quite often 4) often

7 41. Does your child use normal cowmilk products? 42. Are there any restrictions in the child's diet? 42b. if YES, what?

8 ALLERGY AND ASTHMA QUESTIONS TO CHILD S MOTHER 43. Has the child's mother ever had allergic rhinitis (pollen, dust mite, animals)? 43b. if YES, what caused it? 43c. if YES; mother had symptoms during childhood, but not after turning 16 43d. if YES, mother still has symptoms, but doctor has not confirmed them 43e. if YES, mother still has symptoms and need for follow-up (doctor) 44. Has the child's mother ever had doctor diagnosed asthma? 44b. if YES, mother had symptoms during childhood, but not after turning 16 44c. if YES, mother still has symptoms of asthma, but doctor has not confirmed them 44d. if YES, mother still has symptoms and need for prescription drugs 44e. if YES, the cause of asthma symptoms (for example allergens, stress, cold air, flus, drugs, occupational factors) 44f. if YES, where was the diagnosis made?

9 45. Has the child's mother ever had doctor diagnosed food allergy? 45b. if YES, which allergies have been confirmed with skin prick test or blood sample 45c. if YES, which allergies have been confirmed with food challenge under doctors supervision 45d. if YES, other food allergies (then those mentioned in 45b or 45c) 45e. if YES, mother had food allergies as a child, but not after turning 16 45f. if YES, which foods still give symptoms 45g. if YES, where were the diagnosis and the tests made 46. Has the child's mother ever had doctor diagnosed atopic eczema 46b. if YES, mother had atopic eczema as a child, but not after turning 16 46c. if YES, mother still has symptoms, but there is need only for creams and mild corticosteroid ointments occasionally or regularly 46d. if YES, mother still has symptoms and need for stronger corticosteroid ointments, tacro- or pimecrolimus ointments or phototherapy 46e. if YES, where was the diagnosis made?

10 ALLERGY AND ASTHMA QUESTIONS TO CHILD S FATHER 47. Has the child's father ever had allergic rhinitis (pollen, dust mite, animals)? 47b. if YES, what caused it? 47c. if YES; father had symptoms during childhood, but not after turning 16 47d. if YES, father still has symptoms, but doctor has not confirmed them 47e. if YES, father still has symptoms and need for follow-up (doctor) 48. Has the child's father ever had doctor diagnosed asthma? 48b. if YES, father had symptoms during childhood, but not after turning 16 48c. if YES, father still has symptoms of asthma, but doctor has not confirmed them 48d. if YES, father still has symptoms and need for prescription drugs 48e. if YES, the cause of asthma symptoms (for example allergens, stress, cold air, flus, drugs, occupational factors) 48f. if YES, where was the diagnosis made?

11 49. Has the child's father ever had doctor diagnosed food allergy? 49b. if YES, which allergies have been confirmed with skin prick test or blood sample 49c. if YES, which allergies have been confirmed with food challenge under doctors supervision 49d. if YES, other food allergies (then those mentioned in 45b or 45c) 49e. if YES, mother had food allergies as a child, but not after turning 16 49f. if YES, which foods still give symptoms 49g. if YES, where were the diagnosis and the tests made 50. Has the child's father ever had doctor diagnosed atopic eczema 50b. if YES, father had atopic eczema as a child, but not after turning 16 50c. if YES, father still has symptoms, but there is need only for creams and mild corticosteroid ointments occasionally or regularly 50d. if YES, father still has symptoms and need for stronger corticosteroid ointments, tacro- or pimecrolimus ointments or phototherapy 50e. if YES, where was the diagnosis made?