RESPIRATORY SYSTEM - PHARMACOLOGY-

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1 RESPIRATORY SYSTEM - PHARMACOLOGY- PULSE - Mast cell stabilizers : a.have safe profile, so they're recommended for pregnant & children b.they work by blocking IgE receptors on mast cells - There is a case of a child that developed rash or urticaria due to penicillin..and we must give him another drug instead of penicillin? a. Imipinem b. Aztreonam - Which of the statement about antihistamines is incorrect? a.antihistamines work in receptor H1 b. 2nd generation small and less polar c.antihistamines work in H1 receptor in allergic rhinitis - A case about a boy 10 year old with TB, which of the following the correct statement? Answer: We give his mother isoniazid but not to his younger siblings i.e.brothers& sisters - A case about a patient with asthma; the question was: Which of the following regimens is not PROVEN to be effective? Answer: Scheduling doses for LABA.

2 - The primary use for combination in the treatment of TB is: Answer: To avoid the resistance - Regarding clarithromycin and erythromycin, what is the major difference? Answer: Clarithromycin is used in M.Avium EHSAN -Patient with Aspirin induced asthma, which of the following drugs is the best controller : - Leukotrienes inhibitors -Corticosteriods - Which of the following about Dextromethorphan is false : - suppress the mucociliary mechanism - structurally related to Opiods - has no CNS effect - The most powerful agent that treats smooth muscle hyperreactivity in asthma is : Answer: Corticosteroids

3 - One of the following statement about the treatment of asthma is false : - Cromylglycerol is a mast cell stabilizer - The best drugs for rapid rescue is luekotrine inhibitors - Salmeterol is a long acting drug - All of the following are characteristics of 1st generation anti-histamine H1 drugs, except : - have anticholinergic effect. -are excreted unchanged in the urine. - have a relatively short period of action. - All of the following could be associated with antihistamine H1 (1st generation) overdose except : Answer: excessive sweating -Which of the following drugs causes sunlight sensitivity in white/caucasian people? Answer: Tetracycline -The most important drug for TB : Answer: Isoniazid - Drug used in TB.. and affects the eyes (something like this). Answer: Ethambutol - About Carbapenems : Answer: Covers Gram +ve and Gram -ve

4 HOPE &SAMA -Which of the following is the best treatment for a pregnant woman with Mycoplasma Pneumonia? a. Doxycycline b. Ciprofloxacin c. Azithromycin d. Amoxicillin -Which of the following is true about the traditional histamines? Answer: They work both centrally and peripherally -Which of the following is best indicated in the treatment of asthma? Answer: Selective β-2 Agonists -Which of the following drugs isn t an anti-inflammatory drug? a. Corticosteroids b. Leukotriene Inhibitors c. Monoclonal IgE antibodies d. Theophylline -Which of the following is best indicated in the management of asthma? Answer: Inhaled corticosteroids* -Which of the following slows down the absorption of tetracyclines?

5 Answer: Milk -Which of the following drugs causes the production of red orange urine? Answer: Rifampin (Rifampicin) -Which of the following is correctly matched? Answer: Captopril Dry Cough -Which of the following drugs restores the ability to stimulate β-2 receptors? Answer: Beclomethasone (Note: this was the only corticosteroid mentioned in the answers) -Which of these is true about Ipratropium? a. It's an effective drug in treatment of COPD b. It's taken orally c. It's the drug of choice for asthma -Which of the following is an antitussive? a. Loratadine b. Dextromethorphan c. Prednisolone -DOC in the treatment of candida is:

6 Answer: ketoconazole -All of the followings cause occupational asthma EXCEPT: a. Formaldehyde b. Chloride c. Diisocyanate -Theophylline is used in: a. pulmonary edema b. bronchial asthma c. All of listed -Which is related to 2nd generation of antihistamine: Answer: Loratadine -Which of these is best given to children sensitive to penicillin? Answer:Macrolides -Which of these is given for maintenance in asthma? Answer:Prednisolone -Milk is contraindicated with the use of which drug? Answer: Tetracycline

7 -Which drug cannotbe given with gentamycin? Answer: Furosemide

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