Commonly Used Medicines (Both Prescription and Over-the-Counter) That Interact With Alcohol
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1 Commonly Used Medicines (Both Prescription and Over-the-Counter) That Interact With Alcohol Symptom/Disorders Medication (Brand name) Medication (Generic name) Some possible reactions with alcohol Allergies/Colds/Flu Alavert Loratadine Drowsiness, dizziness; increased risk for overdose Atarax Hydroxyzine Benadryl Diphenhydramine Clarinex Claritin, Claritin-D Dimetapp Cold &Allergy Sudafed Sinus & Allergy Triaminic Cold & Allergy Tylenol Allergy Sinus Tylenol Cold & Flu Zyrtec Desloratadine Loratadine Brompheniramine Cetirizine Angina (chest pain), coronary heart disease Isordil Isosorbide Nitroglycerin Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting Anxiety and epilepsy Ativan Lorazepam Drowsiness, dizziness; increased risk for overdose; BuSpar Buspirone slowed or difficulty breathing; impaired motor Klonopin Clonazepam control; unusual behavior; memory problems Librium Chlordiazepoxide Paxil Valium Paroxetine Diazepam
2 Xanax Alprazolam Herbal preparations (Kava Kava) Liver damage, drowsiness Arthritis Celebrex Celecoxib Ulcers, stomach bleeding, liver damage Naprosyn Naproxen Voltaren Diclofenac Attention and concentration (Attention deficit/hyperactivity disorder) Adderall Concerta, Ritalin Amphetamine/dextroamphetamine Methylphenidate Dexedrine Dextroamphetamine Focalin Strattera Dexmethylphenidate Atomoxetine Dizziness, drowsiness, impaired concentration (methylphenidate, dexmethylphenidate); possible increased risk for heart problems (amphetamine, dextroamphetamine, lisdexamfetamine); liver damage (atomoxetine) Vyvanse Lisdexamfetamine Blood clots Coumadin Warfarin Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks Cough Delsym, Robitussin Cough Dextromethorpan Drowsiness, dizziness; increased risk for overdose Robitussin A C Guaifenesin + codeine Depression Abilify Aripriprazone Drowsiness, dizziness; increased risk for overdose; Anafranil Clomipramine increased feelings of depression or hopelessness Celexa Citalopram (all medications); impaired motor control (quetiapine, Clozaril Clozapine mirtazapine); increased alcohol effect (bupropion); Cymbalta Duloxetine liver damage (duloxetine) Monoamine oxidase Desyrel Trazodone inhibitors (MAOIs), such as tranylcypromine and Effexor Venlafaxine phenelzine, when combined with alcohol, may result in
3 Elavil Amitriptyline serious heart-related side effects. Risk for dangerously Geodon Ziprasidone high blood pressure is increased when MAOIs are Invega Paliperidone mixed with tyramine, a byproduct found in beer and Lexapro Escitalopram red wine Luvox Nardil Fluvoxamine Phenelzine Norpramin Desipramine Pamate Paxil Pristiq Prozac Tranylcypromine Paroxetine Desevenlafaxine Fluoxetine Remeron Mirtazapine Risperdal Risperidone Seroquel Quetiapine Serzone Nefazodone Symbyax Fluoxetine/Olanzapine Wellbutrin Bupropion Zoloft Zyprexa Sertraline Olanzapine Herbal preparations (St. John s Wort) Diabetes Diabinese Chlorpropamide Glucotrol Glipizide Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, Glucophage Metformin sudden changes in blood pressure); symptoms of nausea and weakness may Glynase, DiaBeta, Glyburide occur (metformin)
4 Micronase Orinase Tolinase Tolbutamide Tolazamide Enlarged prostate Cardura Doxazosin Dizziness, light headedness, fainting Flomax Tamsulosin Hytrin Terazosin Minipress Prazosin Heartburn, indigestion, sour stomach Axid Nizatidine Rapid heartbeat; increased alcohol effect; sudden Reglan Metoclopramide changes in blood pressure (metoclopramide) Tagamet Cimetidine Zantac Ranitidine High blood pressure Accupril Quinapril Dizziness, fainting, drowsiness; heart problems Calan Verapamil such as changes in the heart s regular heartbeat Capozide Hydrochlorothiazide (arrhythmia) Cardura Doxazosin Catapres Clonidine Cozaar Hytrin Lopressor HCT Lotensin Losartan Terazosin Hydrochlorothiazide Benzapril Minipress Prazosin Norvasc Prinivil, Zestril Amlodipine mesylate Lisinopril Vaseretic Enalapril High cholesterol Advicor Lovastatin + Niacin Liver damage (all medications); increased
5 Altocor Lovastatin flushing and itching (niacin), increased stomach bleeding Crestor Rosuvastatin (pravastatin + aspirin) Lipitor Mevacor Niaspan Atorvastatin Lovastatin Niacin Pravachol Pravastatin Pravigard Pravastatin + Aspirin Vytorin Ezetimibe + Simvastatin Zocor Simvastatin Infections Acrodantin Nitrofurantoin Fast heartbeat, sudden changes in blood pressure; Flagyl Metronidazole stomach pain, upset stomach, vomiting, Grisactin Griseofulvin headache, or flushing or redness of the face; liver Nizoral Ketoconazole damage (isoniazid, ketoconazole) Mood stabilizers Nydrazid Isoniazid Seromycin Cycloserine Tindamax Tinidazole Zithromax Azithromycin Depakene, Depakote Eskalith, Eskalith C R, Lithobid Valproic acid Lithium Drowsiness, dizziness; tremors; increased risk for side effects, such as restlessness, impaired motor control; loss of appetite; stomach upset; irregular bowel movement; joint or muscle pain; depression; liver damage (valproic acid) Muscle pain Flexeril Cyclobenzaprine Drowsiness, dizziness; increased risk of seizures; Soma Carisoprodol increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems Nausea, motion sickness Antivert Meclizine Drowsiness, dizziness; increased risk for overdose Dramamine Dimenhydrinate
6 Phenergan Promethazine Pain (such as muscle ache, minor arthritis pain), fever, inflammation Advil Ibuprofen Stomach upset, bleeding and ulcers; liver damage Aleve Naproxen (acetaminophen); rapid heartbeat Excedrin Aspirin, Acetaminophen Motrin Ibuprofen Tylenol Acetaminophen Seizures Dilantin Phenytoin Drowsiness, dizziness; Horizant, Neurontin Keppra Gabapentin Levetiracetam Klonopin Clonazepam increased risk of seizures (levetiracetam, phenytoin); unusual behavior and changes in mental health (such as thoughts of suicide) (topiramate) Lamictal Lyrica Tegretol Phenobarbital Lamotrigine Pregabalin Carbamazepine Topamax Topiramate Trileptal Oxcarbazepine Severe pain from injury, postsurgical care, oral surgery, migraines Darvocet N Demerol Barbiturates Propoxyphene Merepidine Fiorinal Butalbital + codeine with codeine Percocet Oxycodone Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems Vicodin Hydrocodone Sleep problems Ambien Zolpidem Drowsiness, sleepiness, dizziness; slowed or Lunesta Eszopiclone difficulty breathing; impaired motor control; unusual
7 Prosom Estazolam behavior; memory problems Restoril Temazepam Sominex Diphenhydramine Unisom Doxylamine Herbal preparations (chamomile, valerian, lavender) Increased drowsiness
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