H. Röcken, M. Abdel-Bary, E. Akcöltekin, P. Budz, T. Stephani, J. Wittschen
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1
2 : Medical Operation of the 2 nd Machine, Production and Commissioning Status of Machines No. 3 to 7 H. Röcken, M. Abdel-Bary, E. Akcöltekin, P. Budz, T. Stephani, J. Wittschen VARIAN Medical Systems Particle Therapy GmbH Friedrich-Ebert-Str. 1 D BERGISCH GLADBACH GERMANY
3 : Medical Operation of the 2 nd Machine, Production and Commissioning Status of Machines No. 3 to 7 H. Röcken, M. Abdel-Bary, E. Akcöltekin, P. Budz, T. Stephani, J. Wittschen VARIAN Medical Systems Particle Therapy GmbH Friedrich-Ebert-Str. 1 D BERGISCH GLADBACH GERMANY
4 VARIAN PT? Former ACCEL Instruments was acquired in 2007 by VARIAN Medical Systems and became in 2009 Varian Medical Systems Particle Therapy GmbH Further split-ups: > RI Research Instruments GmbH > BASC Bruker Advanced Supercon GmbH 4
5 OUTLINE Introduction Operating Cyclotrons #1 and #2 Patient Treatment / Uptime Statistics Cyclotrons under Commissioning #3 Assembly, SC Magnet Ramping, Test Quench, Magnetic Field Mapping Examples for New Components Solid State Amplifier, Digital Low Level RF Cyclotron Production Site Production of Next Machines #4, #5, #6, #7 Cyclotron and Scanning Nozzle Test Cell Conclusion 5
6 VARIAN PT Cyclotron System Parameters (Engineering Goals) Beam - Energy 250 MeV - Extracted current (max) 800 na - Emittance of extracted beam < 3 / 5 π mm mrad (2σ) - Momentum spread Δp/p ±0.04% (i.e. 250MeV) - Number of turns Extraction efficiency (multi-turn extraction mode) ~80% - Dynamic range for intensity modulation 1:800 - Fast intensity modulation via electrostatic deflector, >10% in 100 μs Iron Yoke - Outer diameter 3.1 m - Height 1.6 m - Weight <90 t SC Magnet - Stored energy 2.5 MJ - Central field 2.4 T - Max. field at the coil <4 T - Operating current 160 A - Rated power of cryocoolers 40 kw RF System - Frequency 72.8 MHz (2 nd harmonic) - Voltage source to puller extraction radius 80 kv / 130 kv - RF power 115 kw 6
7 Operating VARIAN PT Cyclotrons #1 and #2 1. Paul Scherrer Institut PSI (CH), treating patients since beginning of Rinecker Proton Therapy Center RPTC (D) This facility is widely equipped with VARIAN technology, like superconducting compact 250 MeV proton cyclotron degrader for energy adjustment energy selection system for energy filtering beam line for beam transportation 4 rotational isocentric gantries for 360 irradiation + 1 fixed beam for head / neck treatments delivery nozzles providing pencil beam spot scanning safety systems treatment control software treating patients since beginning of 2009! 7
8 Patient Treatment at RPTC On website : PATIENT TREATMENT STARTED MARCH 16 th, 2009 TREATMENT REPORTS ARE AVAILABLE STATUS REPORTS AND MEDICAL CASE STUDIES ARE AVAILABLE 8
9 Patient Treatment at RPTC On website : PATIENT TREATMENT STARTED MARCH 16 th, 2009 TREATMENT REPORTS ARE AVAILABLE STATUS REPORTS AND MEDICAL CASE STUDIES ARE AVAILABLE 9
10 RPTC Uptime during Patient Treatment RPTC presentation on PTCOG 48 conference (specialized particle therapy event) 6 months after start of operation: Poster presented by RPTC at PTCOG 48 10
11 RPTC Operating Time / Facility Uptime User treats patients 6 days/week, 8-10 hrs/day (8hrs officially scheduled) Commissioning of gantries / scanning nozzles is continued during nights and weekends, current status: - 3 gantries are handed over to the customer, - the last one will be handed over within these days Treatment facility including cyclotron is operated 24hrs on 6-7 days/week Service is performed every Sunday The RPTC uptime of 97% for the complete treatment facility since startup was determined by the user for daily patient treatment Cyclotron contributes only little to downtime 11
12 VARIAN PT Cyclotrons under Commissioning Cyclotron #3 Assembly and FAT Cyclotron #3 will be widely preassembled, tested (with beam!) in the factory, and shipped to its destination in 2 large lots (upper / lower part). It is currently in the final stage of assembly and is undergoing FATs in parallel. 12
13 VARIAN PT Cyclotrons under Commissioning Cyclotron #3 Assembly and FAT Cyclotron #3 will be widely preassembled, tested (with beam!) in the factory, and shipped to its destination in 2 large lots (upper / lower part). It is currently in the final stage of assembly and is undergoing FATs in parallel. 13
14 VARIAN PT Cyclotrons under Commissioning #3 SC Magnet Ramping and Test Quench First excitation of the superconducting magnet took place on May 18, 2010 on the first attempt. The obligatory test quench could not be forced by fast ramping and had to be triggered by the dedicated quench heaters. After cool down (5 hrs) all forces on the support links as well as the magnetic field map remained unchanged: stable, quench proof and quench tolerant system 14
15 VARIAN PT Cyclotrons under Commissioning #3 SC Magnet Ramping and Test Quench First excitation of the superconducting magnet took place on May 18, 2010 on the first attempt. The obligatory test quench could not be forced by fast ramping and had to be triggered by the dedicated quench heaters. After cool down (5 hrs) all forces on the support links as well as the magnetic field map remained unchanged: stable, quench proof and quench tolerant system 15
16 VARIAN PT Cyclotrons under Commissioning #3 SC Magnet Ramping and Test Quench First excitation of the superconducting magnet took place on May 18, 2010 on the first attempt. The obligatory test quench could not be forced by fast ramping and had to be triggered by the dedicated quench heaters. After cool down (5 hrs) all forces on the support links as well as the magnetic field map remained unchanged: stable, quench proof and quench tolerant system 16
17 VARIAN PT Cyclotrons under Commissioning #3 Magnetic Field Mapping A measured field map is compared to its symmetrized form to reveal deviations from perfect 4-fold symmetry. Initially the field showed a first harmonic of ~29 Gauss. This could be compensated down to <2 Gauss by a simple lateral adjustment of the sc coil. Some remaining deviations on the extraction radius must be shimmed locally. 17
18 VARIAN PT Cyclotrons under Commissioning #3 Magnetic Field Mapping A measured field map is compared to its symmetrized form to reveal deviations from perfect 4-fold symmetry. Initially the field showed a first harmonic of ~29 Gauss. This could be compensated down to <2 Gauss by a simple lateral adjustment of the sc coil. Some remaining deviations on the extraction radius must be shimmed locally. 1 st Harmonic of Initial Field Map 29 Gauss 18
19 VARIAN PT Cyclotrons under Commissioning #3 Magnetic Field Mapping A measured field map is compared to its symmetrized form to reveal deviations from perfect 4-fold symmetry. Initially the field showed a first harmonic of ~29 Gauss. This could be compensated down to <2 Gauss by a simple lateral adjustment of the sc coil. Some remaining deviations on the extraction radius must be shimmed locally. 1 st Harmonic 1 st Harmonic of Initial After Field Compensation Map 29 Gauss <2 Gauss 19
20 VARIAN PT Cyclotrons under Commissioning Solid State Amplifier RF power amplifiers used at PSI and RPTC: 3-stage tetrode tube based, several electrical cabinets for power transformers and high voltage supplies New design is tested: transistor based, 20 parallel working RF power modules Test setup completed a >1000h test with 25kW, allowed reflected power limit >15% Supplied by Cryoelectra GmbH 20
21 VARIAN PT Cyclotrons under Commissioning Solid State Amplifier Currently the final setup consisting of 6 cabinets with a total of 120 power modules is under test in the factory. Via its redundancy, the design features a higher - availability, - maintainability, - cost reduction,... The digitally controlled modularized system provides extended diagnostics capabilities. 21
22 VARIAN PT Cyclotrons under Commissioning Solid State Amplifier Currently the final setup consisting of 6 cabinets with a total of 120 power modules is under test in the factory. Via its redundancy, the design features a higher - availability, - maintainability, - cost reduction,... The digitally controlled modularized system provides extended diagnostics capabilities. RF Power Out 22
23 VARIAN PT Cyclotrons under Commissioning Digital Low Level RF VARIAN will use a digital LLRF with its future systems. The dllrf has already passed performance tests at the supplier and will be delivered in September to the VARIAN factory for system integration tests. Like the SSAmp, the dllrf is designed for high redundancy. This yields a high fault tolerance and increases system uptime. The dllrf is faster than the previously used system and provides much more diagnostic signals and functionality. 23
24 VARIAN PT Cyclotrons under Commissioning Digital Low Level RF VARIAN will use a digital LLRF with its future systems. The dllrf has already passed performance tests at the supplier and will be delivered in September to the VARIAN factory for system integration tests. Like the SSAmp, the dllrf is designed for high redundancy. This yields a high fault tolerance and increases system uptime. The dllrf is faster than the previously used system and provides much more diagnostic signals and functionality. Supplied by Cryoelectra GmbH 24
25 VARIAN PT Cyclotrons under Commissioning Digital Low Level RF VARIAN will use a digital LLRF with its future systems. The dllrf has already passed performance tests at the supplier and will be delivered in September to the VARIAN factory for system integration tests. Like the SSAmp, the dllrf is designed for high redundancy. This yields a high fault tolerance and increases system uptime. The dllrf is faster than the previously used system and provides much more diagnostic signals and functionality. Supplied by Cryoelectra GmbH 25
26 VARIAN PT Cyclotrons under Commissioning Digital Low Level RF VARIAN will use a digital LLRF with its future systems. The dllrf has already passed performance tests at the supplier and will be delivered in September to the VARIAN factory for system integration tests. Like the SSAmp, the dllrf is designed for high redundancy. This yields a high fault tolerance and increases system uptime. The dllrf is faster than the previously used system and provides much more diagnostic signals and functionality. Supplied by Cryoelectra GmbH 26
27 VARIAN PT Cyclotron Production Site Overview Production site near Cologne / Germany Allows assembly of up to 6 cyclotrons in parallel and up to 8-12 cyclotrons / year 27
28 VARIAN PT Cyclotron Production Site Overview Production site near Cologne / Germany Allows assembly of up to 6 cyclotrons in parallel and up to 8-12 cyclotrons / year 28
29 VARIAN PT Cyclotron Production Site Assembly Stands 29
30 VARIAN PT Cyclotron Production Site Assembly Stands 30
31 VARIAN PT Cyclotron Production Site Assembly Stands 31
32 VARIAN PT Cyclotron Production Site Assembly Stands 32
33 VARIAN PT Cyclotron Production Site Assembly Stands 33
34 VARIAN PT Cyclotron Production Site Assembly Stands 34
35 VARIAN PT Cyclotron Production Site Assembly Stands 35
36 Production of Next Machines #4, #5, #6, #7 #4: All major components are ready, coil winding and assembly of pole caps is underway #5: Fine machined iron yoke and pole caps are in the factory under inspection #6, #7: Iron parts and long lead items are ordered (iron is casted and forged these days) Expected build sequence is ~2 cyclotrons per year at the moment #4 coil winding pole caps yoke rings #5 pole caps yoke rings 36
37 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 37
38 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 38
39 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 39
40 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 40
41 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 41
42 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 42
43 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. This enables the delivery of factory beam tested systems. The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 43
44 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans ¾ Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. ¾ This enables the delivery of factory beam tested systems. ¾ The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 44
45 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans ¾ Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. ¾ This enables the delivery of factory beam tested systems. ¾ The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 45
46 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans ¾ Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. ¾ This enables the delivery of factory beam tested systems. ¾ The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 46
47 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans ¾ Adjacent to the manufacturing hall VARIAN has built a concrete bunker for cyclotron and scanning nozzle tests, the so-called Test Cell. ¾ This enables the delivery of factory beam tested systems. ¾ The Test Cell is finalized this month and cyclotron #3 will move in after magnetic shimming. 47
48 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans We plan to test all RF components, ion source, slit systems, extractors, diagnostics, etc. during a system integration and FAT for cyclotron #3 in this year. 48
49 Cyclotron and Scanning Nozzle Test Cell Factory Beam Test Plans We plan to test all RF components, ion source, slit systems, extractors, diagnostics, etc. during a system integration and FAT for cyclotron #3 in this year. 49
50 VARIAN PT Superconducting Proton Cyclotrons Future Developments The proven design which was built in the past will be improved continuously for the VARIAN PT Cyclotron with regard to reliability maintainability performance upgrades cost reduction Ion Source, Solid State Amplifier, Dee Noses, Digital LLRF, Simplified Media Supply, Iron, Cryosystem, Extraction System, and so on 50
51 VARIAN PT Superconducting Proton Cyclotrons Future Developments The proven design which was built in the past will be improved continuously for the VARIAN PT Cyclotron with regard to reliability maintainability performance upgrades cost reduction Ion Source, Solid State Amplifier, Dee Noses, Digital LLRF, Simplified Media Supply, Iron, Cryosystem, Extraction System, and so on 51
52 VARIAN PT Superconducting Proton Cyclotrons Future Developments The proven design which was built in the past will be improved continuously for the VARIAN PT Cyclotron with regard to reliability maintainability performance upgrades cost reduction Ion Source, Solid State Amplifier, Dee Noses, Digital LLRF, Simplified Media Supply, Iron, Cryosystem, Extraction System, and so on 52
53 Conclusion Operating & Future VARIAN PT Cyclotrons * Paul Scherrer Institute (PSI), treating patients since beginning of * Rinecker Proton Therapy Center (RPTC), treating patients since beginning of Gantry is handed over right now. * A contract for the next complete PT installation with a customer from the USA has been signed. * There are more projects in Europe and the USA in the pipeline. * Cyclotron #3 is currently undergoing FATs. * Cyclotron #4 parts are currently assembled in the VARIAN factory. * Iron #5 is under inspection in the factory. * Irons #6 and #7 are currently being casted and forged more to come 53
54 Team s Charity Run for the Children s Cancer Ward of the University Hospital in Cologne: Thank you! 54
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