Introducing the TrueBeam STx system with Novalis Radiosurgery.

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1 Introducing the TrueBeam STx system with Novalis Radiosurgery.

2 For the best minds in radiosurgery. TrueBeam STx with Novalis Radiosurgery. As radical as the best minds in radiosurgery, the TrueBeam STx system with Novalis Radiosurgery expands the boundaries of traditional surgery. These revolutionary tools created by Varian Medical Systems and Brainlab world leaders in radiosurgery seamlessly integrate and choreograph powerful imaging and treatment systems. The combined technologies each heralded for accuracy and precision now extend the power of surgeons to treat a variety of clinical targets in more patients than ever before with a noninvasive surgical beam. In the hands of the forward-thinking surgeon, it changes everything.

3 Expand your practice with innovative new treatments. The high precision, accuracy and visibility of TrueBeam STx with Novalis Radiosurgery give you what you need to eliminate even complex tumors. With such unsurpassed technology in your hands, you gain the ability to expand your practice by treating in new and innovative ways. Now, you can spare more surrounding critical structures and deliver more ablative treatments with leading-edge delivery of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). These techniques are enhanced by a wide variety of sophisticated imaging technologies for optimal visualization of the tumor and surrounding healthy tissues. You can deliver extremely high doses of radiation from many directions precisely and efficiently to destroy a focused target. Frameless radiosurgery offers flexible treatment protocols combined with intelligently decoupled treatment steps Scan/Plan/Treat offering benefits to both neurosurgeons and patients. System intelligence gives you control. The heart of the TrueBeam STx system with Novalis At the heart of TrueBeam STx with the Novalis Program is Radiosurgery contains powerful new hardware and powerful new software that seamlessly choreographs the software that seamlessly choreograph the technology s technology s complex motion, speed, precision and imageguided systems with virtually instantaneous fluidity. motion, precision and image-guidance. You deliver treatments with a precise surgical beam. Ideal You deliver for submillimeter treatments targeting, with the most it enables precise treatments surgical beam of on previously the market. untreatable Ideal for smaller tumors. targets, With a it volumetric also enables CT on treatments a radiosurgery of previously platform, untreatable you have exceptional tumors. In fact, image unrivaled image guidance through an in-room CT device and a 6D robotic couch lets you locate soft tissues, including the guidance. For tumors that move with respiration, you can brain, spine, lung, liver and prostate, for superior targeting now pulse the beam on and off in precise synchrony with and visualization, throughout the course of treatment. respiration, thereby treating what you planned to treat. Moreover, you can now address changes to daily respiration These and motion-managed, intrafraction variations image-guided with adaptive treatments gating. help you increase system efficiency so you can treat more patients Because than these ever motion-managed, before. image-guided treatments help you increase speed and system efficiency, you can treat many more patients than ever before. Pre-treatment to post-treatment: you re in control. Your multidisciplinary team works efficiently and easily thanks to TrueBeam STx with Novalis Radiosurgery. Predefine radiosurgical protocols Remotely plan and review treatments Retain control throughout the radiosurgery treatment and beyond It s all made possible by a powerful suite of intuitive software tools that allows you to conveniently work from your own surgical environment.

4 Case examples Multiple MetastasEs Spine Spine Metastasis treated with SRS Acoustic Neuroma LUNG Stage-I non-small cell Lung Cancer treated with SBRT Trigeminal Neuralgia LIVER Hepatocellular Carcinoma treated with SBRT glomus jugulare PROSTATE Prostate Adenocarcinoma treated with SRT Case examples are examples of targets that can be treated using the TrueBeam STx system with Novalis Radiosurgery.

5 2 Product features 3 Treatment beam Treatment imaging Treatment management High-Definition 120 Multileaf Collimator (HD120 MLC) > Unrivaled precision The finest leaves for the widest range of applications. 2. X-ray Energies > Tailor treatments for each patient Up to seven X-ray energies let you tailor treatments. Particularly suited to deep-seated tumors. 3. High-Intensity Mode > Maximizes radiosurgical efficiency and precision Deliver treatments 2.4 to 4 times faster with a dose delivery rate that is double the output of most other radiosurgery. 4. Cone-beam CT (CBCT) > See volumetric soft-tissue anatomy during radiosurgery with kilovoltage 3-D cone-beam CT images. Acquire hundreds of CT slices in less than a minute. 5. MV Imaging > See what you re treating while you re treating from the perspective of the treatment beam, almost as though the beam is a virtual blade. 6. kv Imaging > Fast room-based imaging at any couch angle Confirm tumor location with 2-D images prior to treatment or at multiple intervals during treatment. > Fluoroscopic imaging facilitates temporal tissue assessment for greater target positioning accuracy. Integrated Software Tools > The Eclipse treatment planning system enables the use and operation of RapidArc for SRS and SBRT. > iplan treatment planning software offers clinicians a precise and simple process for completing the most SRS and SBRT sophisticated plans. > iplan Net remote treatment planning software establishes a system for collaboration between team members and fosters informed decision making. > The ARIA oncology information system provides for offline and remote treatment management.

6 The TrueBeam STx system with Novalis Radiosurgery: designed with visionaries in mind. There are individuals who aspire to do more and do it better for the advancement of radiosurgery. The TrueBeam STx system with Novalis Radiosurgery was designed for these leaders. Visionaries who, throughout their careers, have pushed the boundaries of the possible. Visionaries like you.

7 USA Headquarters California Palo Alto, CA Tel: Fax: varian.com USA Regional Offices California Corona, CA Tel: Fax: Georgia Marietta, GA Tel: Fax: Illinois Des Plaines, IL Tel: Fax: New Jersey Clark, NJ Tel: Fax: European Headquarters Switzerland International AG Zug, Switzerland Tel: Fax: Austria Gesellschaft m.b.h. Voesendorf, Austria Tel: Fax: Belgium Belgium N.V./S.A. Diegem, Belgium Tel: Fax: Finland Finland Oy Helsinki, Finland Tel: Fax: France France Buc, France Tel: Fax: Germany Deutschland GmbH Darmstadt, Germany Tel: Fax: India International (India) Pvt Ltd Mumbai, India Tel: Fax: Chennai, India Tel: Fax: Italy Italia, S.p.A. Cernusco s/n (MI), Italy Tel: Fax: Netherlands Nederland B.V. Houten, Netherlands Tel: Fax: Scandinavia Scandinavia AS Herlev, Denmark Tel: Fax: Spain/Portugal Ibérica, S.L. Madrid, Spain Tel: Fax: UK/Ireland UK Ltd. Crawley, West Sussex, UK Tel: Fax: Asian Headquarters Hong Kong Pacific, Inc. Kowloon, Hong Kong Tel: Fax: China China Ltd. Beijing, P.R. China Tel: Fax: Japan K.K. Chuo-ku, Tokyo, Japan Tel: Fax: Latin American Headquarters Florida Miami, FL USA Tel: Fax: Brazil do Brasil Ltda. São Paulo, Brazil Tel: Fax: Australian Headquarters Australia Australasia Pty Ltd. Sydney, Australia Tel: Fax: Varian Medical systems. All rights reserved. Varian,, Eclipse, ARIA and TrueBeam are registered trademarks and trademarks of, Inc. Brainlab is a registered trademark of Brainlab AG in Germany and/or the US. Novalis and iplan are registered trademarks of Brainlab. RAD /10 (5,000)

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