Ellen Feigal, MD, Acting Director. Mission Statement

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1 Ellen Feigal, MD, Acting Director Mission Statement a a national program of funding cancer research, that improves the lives of the American Public by discovering better ways to detect, assess, cure, and control cancer.

2 DCTD Programs Cancer Imaging Program (Formerly Biomedical Imaging Program) Cancer Diagnosis Program Cancer Therapy Evaluation Program Developmental Therapeutics Program Radiation Research Program Biometric Research Branch

3 DCTD Training Opportunities Cancer Research Training, Career Development and Education Opportunities within the NCI Comprehensive Minority Biomedical Branch of the NCI Training Opportunities: Training Opportunities within the DCTD Institutional Clinical Oncology Research Career Development Program

4 Cancer Disparities Research Partnerships $22M Radiation oncology-based 5-year pilot grant program that addresses cancer disparities seen in certain U.S. populations. (Six awards) Supports the planning, development and conduct of: radiation oncology clinical research trials and infrastructure; partnerships between the Grantee and experienced radiation oncologists of NCI-sponsored cancer research institutions; - TELESYNERGY Systems at Grantee and Partner.

5 CDRP Target Populations: Segments of the U.S. population experiencing cancer disparities: African Americans Asians Pacific Islanders Hispanics/Latinos Native Indians Native Alaskans People with low socioeconomic status

6 CDRP Objectives: Build and stabilize collaborative clinical research capabilities of institutions providing radiation oncology care to low income/minority populations in the community Increase the number of clinical scientists engaged in radiation oncology research Develop long-term relationships between new research sites and seasoned, experienced NCI-sponsored research institutions Develop new research sites to a level of competitive application for independently funded research programs in radiation oncology clinical trials and biomedical research

7 CDRP Grantees: U.S. Health care institutions: Necessary facilities Staff expertise Radiation therapy provided according to current standards; Primary provider of radiation oncology care to one or more of the targeted populations at % greater than the state average; Who serve target populations with a greater cancer incidence and/or mortality than the national average. Partners: NCI-designated Cancer Centers RTOG participating institutions Other NCI-sponsored cooperative group participating institutions

8 CDRP Sites Funded 9/2002 Mercy Health Center (Laredo, Texas) Community of 177,000 is 95% Hispanic 35% of residents live in poverty. Rapid City Regional Hospital (Rapid City, South Dakota) Serves ~100,000 Native Americans from three reservations (Rosebud, Cheyenne River, Pine Ridge) Pine Ridge is poorest county in U.S.

9 House in a Colonia (Laredo, Texas)

10 Examples of Research Projects Mercy Health Center (Laredo, Texas) Comparison of chemo-radiation with low dose rate brachytherapy compared to chemo-radiation with high-dose rate brachytherapy in Hispanic Women with advanced cervix cancer Factors influencing choice of mastectomy versus lumpectomy plus radiation in Hispanic women in early stage breast cancer Hispanic Patient Navigator Services Rapid City Regional Hospital (Rapid City, South Dakota) Analysis of the Ataxia Telangiectasia Mutation (ATM) Gene Product to determine if a genetic basis exists for increased acute radiation toxicities among Native Americans A community survey to identify and document barriers to timely and effective cancer screening, diagnosis and treatment for the Native American community Native American Patient Navigator Services

11 CRCHD Patient Navigator Grants An individual or group of individuals who: Help patients navigate health care maze Community outreach to augment local, regional, and national support networks Promotion of clinical trials Organize comprehensive cancer screening programs Arrange or Conduct Community education

12 TELESYNERGY V2 Telemedicine System

13 CDRP SITES & TELESYNERGY Systems Rapid City Regional Hospital UWCCC, Madison Clinical Center, NIH Wheeling Hospital Univ. Texas Health Science Center, San Antonio Mercy Hospital, Laredo Holy Cross Hospital, Fort Lauderdale

14 Cancer Disparities Research Partnerships Contact Information Daniel Petereit, MD Rapid City Regional Hospital Cancer Care Institute 353 Fairmont Boulevard Rapid City, SD Phone: (605) NCI/RRP : Drs. Frank Govern, Norman Coleman, Rosemary Wong or Christen Osburn Yadvindera Bains, MD Mercy Health Center Sanchez Cancer Center 1700 E Saunders Street Laredo, TX Phone: (956) ybains@laredo.mercy.net www3.cancer.gov/rrp/ FG36Q@nih.gov

15 CDRP Awards (Sept 2003) (Pending NCAB Funding Approval) Singing River Hospital Pascagoula, Mississippi Raymond Wynn, MD New Hanover Medical Center Wilmington, North Carolina Patrick McGuire, MD Daniel Freeman Memorial Hospital Inglewood, California Michael Steinberg, MD UPMC-McKeesport Hospital McKeesport, Pennsylvania Dwight Heron, MD