CLINICAL INTERVENTIONAL ONCOLOGY SYMPOSIUM
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1 CLINICAL INTERVENTIONAL ONCOLOGY SYMPOSIUM DAY 1 THURSDAY 14 th MARCH 2019 A FOUNDATION COURSE IN CLINICAL INTERVENTIONAL ONCOLOGY Jim Stynes Room A Welcome Dr Nick Brown INTRODUCTION BASICS IN ONCOLOGY Four (or five) pillars of cancer treatment Why IO is not an optional extra and what it will take to make it mainstream Basics in Cancer Biology How Cancers Develop and How they Metastasise Prof Andy Adam Dr Melissa Eastgate Potential Cure and the Concept of Oligo Metastatic Disease Prof Liz Kenny The Importance of Quality Patient Care and Patient Pathways Prof Liz Kenny BASICS IN CANCER TREATMENT: CANCER DRUGS AND RADIATION TREATMENT : Q & A 15: Afternoon Tea Chemotherapy and Immunotherapy The essentials of chemotherapy and immunotherapy Radiotherapy ERB and SABR The essentials of radiotherapy RENAL CELL CARCINOMA 15: Pathological subtypes of renal masses and distinguishing features Role of biopsy in renal masses TREATMENT OPTIONS: RENAL CELL CARCINOMA AND METASTASES Dr Melissa Eastgate Prof Liz Kenny Surgery: Partial / total nephrectomy Dr Renu Eapen Chemotherapy and immunotherapy for renal cell carcinoma Dr Melissa Eastgate External radiotherapy and SBRT A/Prof Shankar Siva The role of IO in renal cell carcinoma Prof Andy Adam Q & A Sedation and analgesia for IO procedure Types of sedation How to assess patients for fitness for sedation Essential principles and methods of sedation and analgesia Post-procedure analgesia How to manage post-procedural sedation and analgesia Interventional Oncology Networking Event (Invitation Only) Prof Daryl Williams Prof Daryl Williams Clinical Interventional Oncology Symposium sponsored by: 19 TROG2019 trog2019.com
2 CLINICAL INTERVENTIONAL ONCOLOGY SYMPOSIUM DAY 2 Jim Stynes Room A A FOUNDATION COURSE IN CLINICAL INTERVENTIONAL ONCOLOGY Jim Stynes Room A HEPATOCELLULAR CARCINOMA AND HEPATIC METASTASES of Liver HCC and metastases Approach to sampling/biopsy TREATMENT OPTIONS: HCC AND LIVER METASTASES Surgery, Basic techniques and outcomes Mr Graham Starkey Chemotherapy and Immunotherapy Dr Melissa Eastgate External Radiotherapy and SBRT A/Prof David Pryor Q & A The role of IO in Liver Malignancy Biopsies Liver-directed therapies Percutaneous ablation LUNG CANCER Basics of subtypes Tissue sample considerations: - Transbronchial, Percutaneous, FNA v Core Biopsy, liquid biopsy TREATMENT OPTIONS FOR LUNG CANCERS: PRIMARY AND METASTASES Dr Costi Sofocleous Surgery: Basic techniques and outcomes A/Prof Gavin Wright Chemotherapy and Immunotherapy Dr Melissa Eastgate External radiotherapy and SBRT Prof David Ball Q & A The role of IO in lung cancer IO Techniques and when to use them Lung Biopsy CLINICAL PRACTICE Clinical Practice in IO How to run an outpatient clinic Admitting rights (and how to get them), consultations and follow-up Research in IO Future roles and research projects Collaboration with radiation oncology Clinical Interventional Oncology Symposium sponsored by: Dr Costi Sofocleous Prof Andy Adam Dr Nick Brown trog2019.com TROG
3 TECHNICAL RESEARCH WORKSHOP Jim Stynes Room A ADVANCED IMAGING IN CLINICAL TRIALS Olympic Room A SESSION A: EMERGING TECHNIQUES A KIND OF MAGIC Session Chair: Peta Lonski Co-Chair: Prof Tomas Kron Welcome and Introduction to the TRW Peta Lonski Dose outside the treated volume, a workshop on out-of-field dose from photon and particle therapy Dr Rebecca Howell Proton vs Photon Comparative Planning Raymond Dalfsen Plan Challenge: MASTERPLAN Pancreatic SBRT Dr Andrew Oar & Raymond Dalfsen SESSION B: IMAGE REGISTRATION ONE VISION Session Chair: Dr Adam Yeo Co-Chair: Dr Nick Hardcastle "Hands On" - Image Registration Dr Adam Yeo & Dr Nick Hardcastle SESSION C: UPCOMING TROG TRIALS FOR TECHNICAL DISCUSSION BREAKTHRU Session Chair: Mr Dean Wilkinson Co-Chair: Dr Trang Nguyen TD LARK: Real-time monitoring of liver tumour during SABR treatment with KIM Dr Trang Nguyen NINJA: MRI Planning Prof Peter Greer The Potential for Automated Contour Review using the TRAC (The Radiotherapy Atlas Contour) Tool Dr Michael Jameson & A/Prof Lois Halloway TD FET PET Prof Andrew Scott & Prof Martin Ebert Afternoon Tea Exhibition Area SESSION D: CONTOURING, PLANNING, AND TRIAL QA WE ARE THE CHAMPIONS / UNDER PRESSURE Chair: Jo Page Co-Chair: Fahim Siddiqi ProKnow Contouring Accuracy: H&N Prof June Corry & Mr Dean Wilkinson Dose to Medium vs Dose to Water: H&N Planning Prof Tomas Kron Pancreatic Plan Challenge and H&N Contouring Accuracy Winners Announced Closing remarks & survey completion Peta Lonski Technical Research Workshop sponsored by: 21 TROG2019 trog2019.com
4 CLINICAL RESEARCH EDUCATION WORKSHOP Jim Stynes Room A INNOVATE AND INTEGRATE THE CHALLENGE OF CHANGE Yarra Park Room SESSION A: STUDY START UP Session Chair: Sophie Mepham Welcome and introduction to the CREW The initial study start-up process including feasibility, budgets and contracts Facilitated workshop 10: Facilitated discussion SESSION B: REGULATORY THROUGHOUT THE TRIAL Session Chair: Mel Grand Regulatory in the study start-up phase Overview of the Start-up Process from CRO/Sponsor Perspective GCP and other applicable regulatory (trial conduct) Panel discussion E-Consent SESSION C: EMERGING TECHNOLOGIES IMPACTING CLINICAL TRIALS Session Chair: Susan Goode Delivering Cancer Trials Remotely: Satellites, Tele-Trials and Subcontracts Changes in National Ethics and Research Conduct Policies for Managing and Sharing Human Research Data Questions and Answers Afternoon Tea Exhibition Area SESSION D: PATIENT/CARER/ADVOCATE Session Chair: Sue McCullough Carers Couch Where are we now? E-learning module Renee Swanson TROG Cancer Research Mel Grand Chris O Brien Lifehouse Sophie Mepham, Renee Swanson, Mel Grand, Eleanor Allan Sophie Mepham, Renee Swanson, Mel Grand, Eleanor Allan Eleanor Allan Caledonian Training Sarah Berardini IQVIA Sophie Mepham GenesisCare Eleanor Allan, Sarah Berardini, Sophie Mepham Melanie Clarke ROCHE Adam Stoneley ICON Cancer Centre Kate Lemay Australian Research Data Commons Martina Clark Carers Couch Prof Fran Boyle Pam McLean Centre trog2019.com TROG
5 RADIATION ONCOLOGY TRAINEE SMART WORKSHOP Jim Stynes Room A Convenor: Time Jim Stynes Room B Dr Trang Pham Topic Welcome and Introduction A/Prof Farshad Foroudi, President of TROG Cancer Research Introduction to Critical Appraisal Do we really need it? Aren t papers already reviewed? Issues with Randomised Controlled Trials Randomisation Strata Allocation concealment Small Group Session Morning Tea Exhibition Area Time to Event Concepts Censored observations Survival curves Estimates from these curves and comparisons Follow-up issues Comparison Quantifying risk Small Group Session Interpretation of Clinical Trial Results 1 Intention to treat / per protocol Multiple outcomes Tweaking study designs International Guest Speaker Dr Nicholas van As, Medical Director and Consultant Clinical Oncologist, The Royal Marsden Interpretation of Clinical Trial Results 2 Subgroups analyses Interim analyses Competing risk Reaching for the Stars why and how to get involved with clinical trials A/Prof Shankar Siva, Radiation Oncologist, Peter MacCallum Cancer Centre Afternoon Tea Exhibition Area Small Group Session Open Forum Q & A Wrap up - closing Reception Drinks and Canapés onsite at Mantra on Jolimont (Closed event) 23 TROG2019 trog2019.com
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