Organisational challenges faced by Bristol Genetics in the past 18 months

Transcription

1 Organisational challenges faced by Bristol Genetics in the past 18 months Stuart Cook

2 Introduction 1. The move towards 7-day working 2. Transitioning to a new lab facility 3. Improving process efficiency

3 7-day services Drivers Re-configuration 3-day TATs using a calendar week rather than a working week Prenatal/antenatal QF-PCR, BCR-ABL qualitative, Urgent leukaemia FISH Aims Saturday or Sunday or both Geared towards working Monday-Friday Moving to an expanded working week, without expanding staff hours Find a way of safely performing technical tasks Equitable Strategy Task group Senior scientists, GTs and MLAs

4 7-day services Task Mapping Molecular Extraction Folder check Starlims Urgent Extraction Phenol Extraction RNA Lysate RNA Extraction Sequencing Sanger MLPA QF-PCR PCR Reporting CF Real Time PCR PCR Setup Molecular Oncology BCR ABL Qualitative Prenatal Postnatal FISH Cytogenetic Culture Assessment Culture Maintenance Sample setup Direct Harvest Culture setup Spreading Day 1 processing Day 2 processing Scanning Screening Other Specimen Reception

5 7-day services Task workloads not equitable High Frequency Some tasks too specific Enormous training encumbrance Difficult to maintain competencies Incorporate into routine

6 7-day services Molecular Extraction Folder check Starlims Urgent Extraction Phenol Extraction RNA Lysate RNA Extraction Sequencing Sanger MLPA QF-PCR PCR Reporting CF Real Time PCR PCR Setup Molecular Oncology BCR ABL Qualitative Prenatal Postnatal FISH Cytogenetic Culture Assessment Culture Maintenance Sample setup Direct Harvest Culture setup Spreading Day 1 processing Day 2 processing Scanning Screening Other Specimen Reception

7 7-day services Extraction QF-PCR Molecular Urgent Extraction Phenol Extraction RNA Lysate RNA Extraction PCR Reporting Molecular Oncology BCR ABL Qualitative Cytogenetic Postnatal Direct Harvest Culture setup FISH Day 1 processing Day 2 processing Scanning Screening Other Specimen Reception BCR-ABL BCR ABL Qualitative Urgent Extraction RNA Lysate RNA Extraction Extraction Phenol Extraction Promega Tecan Extraction Specimen Reception QF-PCR Setup Reporting Cytogenetics Direct Harvest Sample set-up Day 1 FISH processing Day 2 FISH processing Scanning Screening

8 7-day services Training GT Training Plan (Cytogenetics) Live for 18 months Not fully settled or equitable yet Issues Maintaining competency Staffing pressure

9 New Laboratory Facility Previous Facility Workflow Microscopy (Cytogenetics Scientific Office) Post-PCR Pre-PCR Extraction Specimen reception Slide Prep Culture Molecular Scientific Office

10 New Laboratory Facility Microscopy (Constitutional Scientific Office) Oncology Scientific Office Amplification Post-PCR New Facility Workflow Slide Prep Specimen reception Culture Pre-PCR Extraction

11 New Laboratory Facility Drivers Wider pathology requirements for the Southwest Integration of pathology services (Molecular Hub) Efficiency and financial savings Aims Community laboratory space Centralised extraction and amplification Challenges Space issues Divide between scientific and technical Communication & oversight Moved from Cyto/Molecular teams to a Constitutional/Oncology teams

12 Efficiency Think about the way that we worked as a laboratory minimisation Small changes Solutions Electronic requesting for technical tasks Limit the movement of samples and paperwork throughout the lab Automation Batching work Re-assigned tasks a different approach to technical teams Re-design workspaces Integrated services contracts for equipment, shared reagents Forum for voicing ideas for all staff From the ground up!

13 Acknowledgements 7-day services Task group - Chris Wragg, Ros Allen, Jennifer Glauert, Sharon Gordon and others Content Review Elizabeth Watson Other Contributions - Nicola Jones & Jess Spiers