Trends in cancer incidence in South East England Henrik Møller and all staff at the Thames Cancer Registry, King s College London

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1 Trends in cancer incidence in South East England Henrik Møller and all staff at the Thames Cancer Registry, King s College London 1

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4 Analysts Vicki Coupland Ruth Jack Margreet Lüchtenborg Sharma Riaz Jon Shelton (NCIN) Henrik Møller 4

5 Trends in cancer incidence in South East England Incidence by calendar period Incidence by birth cohort (generation) Projections by calendar period About 50 cancer diagnosis groups 5

6 Population SE England 12m population: 1/4 of England 1/5 of UK

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22 Lay-out of results - example Lung cancer 22

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27 Some cancers with decreasing rates Stomach Lip Cervix Ovary Mesothelioma 27

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33 Cancers related to alcohol drinking Oral and pharyngeal cancer Primary liver cancer 33

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36 Other cancers with increasing rates Oesophageal cancer Kaposi s sarcoma Non-Hodgkin s lymphoma Prostate cancer 36

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42 Total cancer incidence Sum of individual cancer projections (where possible) Model all cancers combined as a single disease 42

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44 All cancers (C00-C96) modelled ASR(E) ASR(E) Period of diagnosis Cohort of birth ASR(E) Period of diagnosis Males Females

45 All cancers excluding prostate (C00-C96 excl. C61) modelled ASR(E) 200 ASR(E) Period of diagnosis Cohort of birth ASR(E) Period of diagnosis Males Females

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47 Sir David Smithers: On some general concepts in oncology with special reference to Hodgkin's disease. Int J Radiat Oncol Biol Phys Immunotherapy in treatment of breast cancer. Proc R Soc Med Endocrine therapy - the future. Proc R Soc Med Fertility after unilateral orchidectomy and radiotherapy for patients with tumours of the testis. Br Med J Where to die. Br Med J Preservation of ovarian function in patients requiring radiotherapy for Hodgkin's disease. Lancet Lymphomas in recipients of renal transplants. Lancet Hodgkin's disease: one entity or two? Lancet Factors influencing survival in patients with Hodgkin's disease. Clin Radiol Immunosuppression and cancer. Lancet Spontaneous regression of cancer. Ann R Coll Surg Engl Survival in 6086 cases of bronchial carcinoma. Lancet Some inferences about the origin of tumours derived from their age distribution. Clin radiol Radiotherapy in the treatment of patients with seminomas and teratomas of the testicle. Br J Urol Some factors other than treatment influencing the prognosis in breast cancer. Acta Unio Int Contra Cancrum Cancer of the breast: a study of short survival in early cases and of long survival in advanced cases Adenocarcinoma of the oesophagus. Thorax Some graphical methods of presenting results of cancer treatment. Br J Radiol Facts and fancies about cancer of the lung. Br Med J

48 Peter Payne: Acute complications of colo-rectal cancer: site, stage and survival. Clin Oncol Glioblastoma multiforme: a controlled trial to assess the value of specific active immunotherapy. Br J Cancer Factors affecting the finding of cancer cells in the blood. Br J Surg Carcinoma of the skin: problems of registration and a tentative analysis of the material registered in Southern and South Eastern England Cancro Cancer registration planning and policy. Postgrad Med J Multiple primary malignant neoplasms in the air and upper food passages: a statistical review. Cancer Some graphical methods of presenting results of cancer treatment. Br J Radiol Bronchial carcinoma: a statistical study of 741 necropsies Br J Cancer Dick Skeet: Manual and computerized cancer registries. IARC Sci Publ Cancer registration: principles and methods. Quality and quality control. IARC Sci Publ Making cancer statistics more informative: measures of the quality of recorded diagnosis Eur J Cancer Clin Oncol Can we achieve 100% ascertainment in cancer registration? Public Health Aetiological factors in cutaneous malignant melanomas seen at a UK skin clinic. J Epidemiol Community Health Prognostic features of long term and short term survivors of metastatic breast cancer. Eur J Cancer Clin Oncol Leukaemia incidence in electrical workers. Lancet Social class and carcinoma of the prostate. Br J Urol

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