COVER STORIES. Hoffman, R.M. Visualization of GFP-expressing tumors and metastasis in vivo. BioTechniques 30, , 2001.
|
|
|
- Sybil Parrish
- 6 years ago
- Views:
Transcription
1 COVER STORIES Hoffman, R.M. Three-dimensional histoculture: origins and applications in cancer research. Cancer Cells 3, 86-92, Hoffman, R.M. Visualization of GFP-expressing tumors and metastasis in vivo. BioTechniques 30, , Bouvet, M., et al. Real-time optical imaging of primary tumor growth and multiple metastatic events in a pancreatic cancer orthotopic model. Cancer Res. 62, , Hoffman, R.M. Green fluorescent protein imaging of tumor cells in mice. Lab Animal 31, 34-41, Hoffman, R.M. GFP- Expressing Metastatic-Cancer Mouse Models. In: Tumor Models in Cancer Research, pp Teicher, B., ed. Totowa, NJ: Humana Press Inc., Hoffman, R.M. Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncology 3, , 2002.
2 Schmitt, C.A., et al. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 1, , John, C.M., et al. Truncated Galectin-3 inhibits tumor growth and metastasis in orthotopic nude mouse model of human breast cancer. Clin. Cancer Res. 9, , Yamauchi, K., et al. Real-time in vivo dual-color imaging of intracapillary cancer cell and nucleus deformation and migration. Cancer Res. 65, , Jiang, P., et al. Tumor cells genetically labeled with GFP in the nucleus and RFP in the cytoplasm for imaging cellular dynamics. Cell Cycle 5, , Hayashi, K., et al. Dual-color imaging of angiogenesis and its inhibition in bone and soft tissue sarcoma. J. Surg. Res. 140, , Amoh, Y., et al. Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function. Cell Cycle 7, , 2008.
3 Zajac, L. Glowing proteins with promising biological and medical applications. Chem Matters 12-14, 2008 (December). Sakuma, S., et al. In vitro/in vivo biorecognition of lectinimmobil-ized fluorescent nano-spheres for human colorectal cancer cells. J Controlled Release 134, 2-10, Hayashi, K., et al. Systemic targeting of primary bone tumor and lung met-astasis of high-grade osteosarcoma in nude mice with a tumorselective strain of Salmonella typhimurium. Cell Cycle 8, , Gros, S.J., et al. Complementary use of fluorescence and magnetic resonance imaging of metastatic esophageal cancer in a novel orthotopic mouse model. Intl J Cancer 126, , Tran Cao, H.S., et al. Metronomic gemcitabine in combination with Sunitinib inhibits multisite meta-stasis and increases survival in an orthotopic model of pancreatic cancer. Mol Cancer Therap 9, , Kimura, H., et al. UV light killing efficacy of fluorescent protein-expressing cancer cells in vitro and in vivo. J. Cell. Biochem 110, , 2010.
4 Logan-Collins, J., et al. Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers. Cancer Res. 70, , Soda, Y., et al. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc. Natl. Acad. Sci. USA 108, , Tran Cao, H.S., et al. Submillimeter-resolution fluorescence laparoscopy of pancreatic cancer in an orthotopic mouse model visualizes metastases not seen with standard laparoscopy. J. Laparoendosc. Adv. Surg. Tech. A 21, , Hassanein, M.K., et al. Stemlike and non-stem human pancreatic cancer cells distinguished by morphology and metastatic behavior. J. Cell. Biochem. 112, , Amoh, Y., et al. In vivo imaging of nuclearcytoplasmic deformation and partition during cancer cell death due to immune rejection. J. Cell. Biochem. 113, , Hoffman, R.M., editor. In Vivo Cellular Imaging Using Fluorescent Proteins: Methods and Protocols. Methods in Molecular Biology, Vol Walker, John M., series ed. Humana Press (Springer Science+ Business Media New York), 2012.
5 Hoffman, R.M. Fluorescent angiogenesis models using Gelfoam implanted in transgenic mice expressing fluorescent proteins. Cerebral Angiogenesis: Methods and Protocols. Methods in Molecular Biology, Richard Milner, ed., Vol. 1135, pp Springer: Hiroshima, Y., et al. Efficacy of Salmonella typhimurium A1-R versus chemotherapy on a pancreatic cancer patientderived orthotopic xenograft (PDOX). J. Cell. Biochem. 115, , 2014 Maawy, A., et al. Specific tumor labeling enhanced by polyethylene glycol linkage of near infrared dyes conjugated to a chimeric anticarcinoembryonic antigen antibody in a nude mouse model of human pancreatic cancer. J. Biomed. Optics 19, , Hoffman, R.M. Transgenic nude mice ubiquitously-expressing fluorescent proteins for colorcoded imaging of the tumor microenvironment. Mouse Genetics: Methods and Protocols. Methods in Molecular Biology, Shree Ram Singh, ed., Vol. 1194, Springer: Matsumoto, Y., et al. Efficacy of tumor-targeting Salmonella typhimurium A1-R on nude mouse models of metastatic and disseminated human ovarian Cancer. J. Cell. Biochem. 115, , Yashiro, M., et al. From hair to heart: nestin-expressing hair-follicle-associated pluripotent (HAP) stem cells differentiate to beating cardiac muscle cells. Cell Cycle 14, , 2015.
this mutation. However, VEM was not effective. The PDOX model thus helped identify
/, Vol. 7, No. 44 Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model Kei Kawaguchi
Imaging Nuclear Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice
Imaging Nuclear Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice KOSUKE HASEGAWA 1, ATSUSHI SUETSUGU 1,2,3, MIKI NAKAMURA 1, TAKURO MATSUMOTO 1, HITOMI AOKI 1, TAKAHIRO KUNISADA
Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug
/, 2017, Vol. 8, (No. 5), pp: 8035-8042 Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug Takashi Murakami
ANTICANCER RESEARCH 35: (2015)
Complementarity of Variable-magnification and Spectralseparation Fluorescence Imaging Systems for Noninvasive Detection of Metastasis and Intravital Detection of Single Cancer Cells in Mouse Models YONG
ANTICANCER RESEARCH 36: (2016) Abstract. Background/Aim: Fluorescence-guided surgery /2016 $
doi:10.21873/anticanres.10988 Color-coded Imaging Enables Fluorescence-guided Surgery to Resect the Tumor Along with the Tumor Microenvironment in a Syngeneic Mouse Model of EL-4 Lymphoma KOSUKE HASEGAWA
INTRODUCTION. Journal of Surgical Research 132, (2006) doi: /j.jss
Journal of Surgical Research 132, 164 169 (2006) doi:10.1016/j.jss.2005.12.028 Dual-Color Imaging of Nascent Blood Vessels Vascularizing Pancreatic Cancer in an Orthotopic Model Demonstrates Antiangiogenesis
Recruitment of Cancer-Associated Fibroblasts and Blood Vessels by Orthotopic Liver Tumors Imaged in Red Fluorescent Protein (RFP) Transgenic Nude Mice
Recruitment of Cancer-Associated Fibroblasts and Blood Vessels by Orthotopic Liver Tumors Imaged in Red Fluorescent Protein (RFP) Transgenic Nude Mice ATSUSHI SUETSUGU 1,2,3, YUKIHIKO HIROSHIMA 2,3, TAKURO
The Cyan Fluorescent Protein Nude Mouse as a Host for Multicolor-coded Imaging Models of Primary and Metastatic Tumor Microenvironments
The Cyan Fluorescent Protein Nude Mouse as a Host for Multicolor-coded Imaging Models of Primary and Metastatic Tumor Microenvironments ATSUSHI SUETSUGU 1,2,3, MOHAMED K. HASSANEIN 1,2, JOSE REYNOSO 1,
2007 AACR Annual Meeting April 14-18, 2007 Los Angeles, CA PRESENTATION SCHEDULE
2007 AACR Annual Meeting April 14-18, 2007 Los Angeles, CA PRESENTATION SCHEDULE Abstract 501 Presentation Title: An imageable bone and multi-organ metastatic model of human neuroblastoma Presentation
ABSTRACT INTRODUCTION
/, 2016, Vol. 7, (No. 52), pp: 85929-85936 Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic
ANTICANCER RESEARCH 36: (2016)
Orthotopic Implantation of Intact Tumor Tissue Leads to Metastasis of OCUM-2MD3 Human Gastric Cancer in Nude Mice Visualized in Real Time by Intravital Fluorescence Imaging TAKASHI MURAKAMI 1,2,3, YONG
Nestin-Linked Green Fluorescent Protein Transgenic Nude Mouse for Imaging Human Tumor Angiogenesis
Research Article Nestin-Linked Green Fluorescent Protein Transgenic Nude Mouse for Imaging Human Tumor Angiogenesis Yasuyuki Amoh, 1,2,3 Meng Yang, 1 Lingna Li, 1 Jose Reynoso, 1 Michael Bouvet, 2 Abdool
ORIGINAL ARTICLE TRANSLATIONAL RESEARCH AND BIOMARKERS. Ann Surg Oncol DOI /s
Ann Surg Oncol DOI 10.1245/s10434-014-4144-1 ORIGINAL ARTICLE TRANSLATIONAL RESEARCH AND BIOMARKERS Ratiometric Activatable Cell-Penetrating Peptides Label Pancreatic Cancer, Enabling Fluorescence-Guided
EDUCATIONAL SEMINAR. Humanized Mouse Models in Pre- Clinical Efficacy Studies in Oncology. BIOCOM CRO Event January 23, 2018
EDUCATIONAL SEMINAR Humanized Mouse Models in Pre- Clinical Efficacy Studies in Oncology BIOCOM CRO Event January 23, 2018 Agenda 8.00 8.30 Registration and networking 8.30 8.45 Introduction, by Jussi
Tumor-educated Macrophages Promote Tumor Growth and Peritoneal Metastasis in an Orthotopic Nude Mouse Model of Human Pancreatic Cancer
Tumor-educated Macrophages Promote Tumor Growth and Peritoneal Metastasis in an Orthotopic Nude Mouse Model of Human Pancreatic Cancer RHIANA S. MENEN 1,2,3*, MOHAMED K. HASSANEIN 1,2*, MASASHI MOMIYAMA
Whole-Body Subcellular Multicolor Imaging of Tumor-Host Interaction and Drug Response in Real Time
Research Article Whole-Body Subcellular Multicolor Imaging of Tumor-Host Interaction and Drug Response in Real Time Meng Yang, 1 Ping Jiang, 1 and Robert M. Hoffman 1,2 1 AntiCancer, Inc. and 2 Department
OMICS Journals are welcoming Submissions
OMICS Journals are welcoming Submissions OMICS International welcomes submissions that are original and technically so as to serve both the developing world and developed countries in the best possible
Chapter 10-3 Regulating the Cell Cycle
Chapter 10-3 Regulating the Cell Cycle Vocabulary: Cyclin Cancer Key Concepts: How is the cell cycle regulated? How are cancer cells different from other cells? I. Introduction A. An Interesting Fact About
Dual-color Imaging of Nascent Angiogenesis and its Inhibition in Liver Metastases of Pancreatic Cancer
Dual-color Imaging of Nascent Angiogenesis and its Inhibition in Liver Metastases of Pancreatic Cancer YASUYUKI AMOH 1,2,3, CHISA NAGAKURA 1, ANIRBAN MAITRA 4, A. R. MOOSSA 2, KENSEI KATSUOKA 3, ROBERT
METACELL. PERSONALIZED CANCER THERAPY USING CIRCULATING TUMOR CELLS (CTCs) METACELL LIQUID BIOPSY
METACELL PERSONALIZED CANCER THERAPY USING CIRCULATING TUMOR CELLS (s) AN EASY WAY TO LIQUID BIOPSY MORE THAN A METASTATIC CELL IN BLOOD A STEP TOWARDS PERSONALIZED CANCER TREATMENT LIQUID BIOPSY REAL-TIME
Beverly A. Teicher, PhD DCTD/NCI. The content reflects my professional opinions, not an NCI policy statement.
Beverly A. Teicher, PhD DCTD/NCI The content reflects my professional opinions, not an NCI policy statement. Outline 1. Transplantable Syngeneic Tumors 2. Human Tumor Xenografts 3. Disseminated Disease
Color-Coded Fluorescent Protein Imaging of Angiogenesis: The AngioMouse Models
3810 Current Pharmaceutical Design, 2008, 14, 3810-3819 Color-Coded Fluorescent Protein Imaging of Angiogenesis: The AngioMouse Models Yasuyuki Amoh 1,*, Kensei Katsuoka 1 and Robert M. Hoffman 2,3 1 Department
POSTER SESSION. Detection of Colon Cancer Metastases With Fluorescence Laparoscopy in Orthotopic Nude Mouse Models
ONLINE FIRST POSTER SESSION Detection of Colon Cancer Metastases With Fluorescence Laparoscopy in Orthotopic Nude Mouse Models Rhiana S. Menen, MD; Sharmeela Kaushal, PhD; Cynthia S. Snyder, MD; Mark A.
Cancer-cell Killing by Engineered Salmonella Imaged by Multiphoton Tomography in Live Mice
Cancer-cell Killing by Engineered Salmonella Imaged by Multiphoton Tomography in Live Mice AISADA UCHUGONOVA 1-3, MING ZHAO 1, YONG ZHANG 1, MARTIN WEINIGEL 4, KARSTEN KÖNIG 3,4 and ROBERT M. HOFFMAN 1,2
Molecular Imaging for Cancer Visualization
Molecular Imaging for Cancer Visualization American College of Surgeons Surgical Simulation Summit Chicago, IL March 16-17, 2018 Michael Bouvet, MD Professor of Surgery University of California San Diego
Mesenchymal Stem Cells and Cancer: Their Interplay
Mesenchymal Stem Cells and Cancer: Their Interplay Gang Li, MBBS, DPhil (Oxon) Stem Cell and Regeneration Program School of Biomedical Sciences Li Ka Shing Institute of Health Sciences Department of Orthopaedics
For personal use only
ASX and Media release 6 April 211 Circadian s Inhibits Tumour Growth in Models of Lung, Ovarian and Prostate Cancer Data demonstrates efficacy of with other therapeutic agents in mouse models of lung,
Juyoun Jin, D.V.M., Ph.D. Institute for Refractory Cancer Research, Samsung Medical Center
Juyoun Jin, D.V.M., Ph.D. Institute for Refractory Cancer Research, Samsung Medical Center Overview of Anticancer Drug Development Discovery Non-clinical development Clinical Trial Target Identification
Imaging the Interaction of Pancreatic Cancer and Stellate Cells in the Tumor Microenvironment during Metastasis
Imaging the Interaction of Pancreatic Cancer and Stellate Cells in the Tumor Microenvironment during Metastasis ATSUSHI SUETSUGU 1,2,3, CYNTHIA S. SNYDER 2, HISATAKA MORIWAKI 3, SHIGETOYO SAJI 3, MICHAEL
Development of the Transgenic Cyan Fluorescent Protein (CFP)-Expressing Nude Mouse for Technicolor Cancer Imaging
ARTICLE Journal of Cellular Biochemistry 107:328 334 (2009) Journal of Cellular Biochemistry Development of the Transgenic Cyan Fluorescent Protein (CFP)-Expressing Nude Mouse for Technicolor Cancer Imaging
AntiCancer, Inc. OncoBrite
BIBLIOGRAPHY 1. Chishima, T., Miyagi, Y., Wang, X., Yamaoka, H., Shimada, H., Moossa, A.R., and Hoffman, R.M. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein
SHREE ET AL, SUPPLEMENTAL MATERIALS. (A) Workflow for tumor cell line derivation and orthotopic implantation.
SHREE ET AL, SUPPLEMENTAL MATERIALS SUPPLEMENTAL FIGURE AND TABLE LEGENDS Supplemental Figure 1. Derivation and characterization of TS1-TGL and TS2-TGL PyMT cell lines and development of an orthotopic
Advantages of multi-color fluorescent proteins for whole-body and in vivo cellular imaging
Journal of Biomedical Optics 104, 041202 July/August 2005 Advantages of multi-color fluorescent proteins for whole-body and in vivo cellular imaging Robert M. Hoffman AntiCancer, Inc. 7917 Ostrow Street
Clinical indications for positron emission tomography
Clinical indications for positron emission tomography Oncology applications Brain and spinal cord Parotid Suspected tumour recurrence when anatomical imaging is difficult or equivocal and management will
Hair Follicle Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin
Research Article Hair Follicle Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Yasuyuki Amoh, 1,2,3 Lingna Li, 1 Meng Yang, 1 Ping Jiang, 1 Abdool R. Moossa, 2 Kensei
IVC History, Cancer Research
Riordan Clinic IVC Academy 5 IVC History, Cancer Research O (slides 81-116) Cytokine Signaling Categories Heal the Wound! Angiogenesis - 62 Inflammation - 69 Differentiation - 53 Oncogene-Activation -
PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland
Page 1 09/10/2013 AD Award Number: W81XWH-12-1-0453 TITLE: The cytoplasm translocation of the androgen receptor cofactor p44 as a target for prostate cancer treatment PRINCIPAL INVESTIGATOR: Zhengxin Wang
Antimetastatic efficacy of adjuvant gemcitabine in a pancreatic cancer orthotopic model
Clinical & Experimental Metastasis 18: 379 384, 2001. 2001 Kluwer Academic Publishers. Printed in the Netherlands. 379 Antimetastatic efficacy of adjuvant gemcitabine in a pancreatic cancer orthotopic
Backgrounder. 1. What are targeted therapies? 2. How do targeted therapies work?
Backgrounder TARGETED THERAPIES FOR CANCER 1. What are targeted therapies? 2. How do targeted therapies work? 3. What are some of the different types of targeted therapy? 4. What are the potential benefits
Copyright. Tocagen Inc. Lead Product Candidate: Toca 511 & Toca FC Preclinical Overview
Lead Product Candidate: Toca 511 & Toca FC Preclinical Overview Toca 511, delivers CD prodrug activator gene selectively to cancer cells Regulatory genes Structural RRV genes CD gene Regulatory genes Toca
CCN1: A NOVEL TARGET FOR PANCREATIC CANCER. Andrew Leask.
CCN1: A NOVEL TARGET FOR PANCREATIC CANCER Andrew Leask CIHR Group in Skeletal Development and Remodeling, Division of Oral Biology and Department of Physiology and Pharmacology, Schulich School of Medicine
Cancer Metronomic Therapy Milan, February 26, 2016
Cancer Metronomic Therapy Milan, February 26, 2016 Metronomic Chemotherapy: Evolution and Development of the Concept Robert S. Kerbel, PhD Senior Scientist Sunnybrook Research Institute Professor, Dept.
Regulating the Cell Cycle
Regulating the Cell Cycle The cell cycle is controlled by regulatory proteins both inside and outside the cell. Cyclins proteins that regulate the timing of the cell cycle in eukaryotic cells. Internal
Tumor responses (patients responding/ patients treated)
Table 1. ACT clinical trial tumor responses and toxicities. a Target antigen Cancer(s) Receptor type Tumor responses (patients responding/ patients treated) Immune-mediated toxicities (patients experiencing
In vivo Color-Coded Imaging of the Interaction of Colon Cancer Cells and Splenocytes in the Formation of Liver Metastases
In vivo Color-Coded Imaging of the Interaction of Colon Cancer Cells and Splenocytes in the Formation of Liver Metastases Michael Bouvet, 1 Kazuhiko Tsuji, 1,2 Meng Yang, 2 Ping Jiang, 2 Abdool R. Moossa,
Antitumor Activity of CUDC-305, a Novel Oral HSP90 Inhibitor, in Solid and Hematological Tumor Xenograft Models
Antitumor Activity of CUDC-5, a Novel Oral HSP Inhibitor, in Solid and Hematological Tumor Xenograft Models Rudi Bao, MD/PhD April 1, 2 AACR 1th Annual Meeting 2 Experimental and Molecular Therapeutics
ABSTRACT. Research Paper
/, Vol. 7, No. 30 Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing s sarcoma patient-derived orthotopic xenograft (PDOX) nudemouse
Understanding and Optimizing Treatment of Triple Negative Breast Cancer
Understanding and Optimizing Treatment of Triple Negative Breast Cancer Edith Peterson Mitchell, MD, FACP Clinical Professor of Medicine and Medical Oncology Program Leader, Gastrointestinal Oncology Department
MELANOMA CANCER TEST
MELANOMA CANCER TEST Efficacy Evaluation of Antitumor Activity of Alka Vita - Alkahydroxy in the LOX-GFP Human Melanoma Model Final Report by: Anti-Cancer Lab San Diego California March 4, 2005 Efficacy
Development of Next-generation Therapeutic
2015 World Biologics Korea Development of Next-generation Therapeutic Antibodies for Treating Ovarian Cancer (Therapeutic Targeting of Tetraspanin8 in Epithelial Ovarian Cancer Invasion and Metastasis)
Subject: Chemoresistance and Chemosensitivity Assays
05-86000-11 Original Effective Date: 12/15/02 Reviewed: 09/27/18 Revised: 10/15/18 Subject: Chemoresistance and Chemosensitivity Assays THIS MEDICAL COVERAGE GUIDELINE IS NOT AN AUTHORIZATION, CERTIFICATION,
ANTICANCER RESEARCH 32: (2012)
Inhibition of Metastasis of Circulating Human Prostate Cancer Cells in the Chick Embryo by an Extracellular Matrix Produced by Foreskin Fibroblasts in Culture RHIANA MENEN 1,4,5, EMMETT PINNEY 2, MOHAMED
Higher Human Biology Unit 1: Human Cells
Higher Human Biology Unit 1: Human Cells Key Area 1.1: Division & differentiation in human cells Learning Outcomes Somatic stem cells divide by mitosis to form more somatic cells. Germline stem cells divide
Supplementary Table 1. Characterization of HNSCC PDX models established at MSKCC
Supplementary Table 1. Characterization of HNSCC PDX models established at MSKCC Supplementary Table 2. Drug content and loading efficiency estimated with F-NMR and UV- Vis Supplementary Table 3. Complete
Targeting tumour associated macrophages in anti-cancer therapies. Annamaria Gal Seminar Series on Drug Discovery Budapest 5 January 2018
Targeting tumour associated macrophages in anti-cancer therapies Annamaria Gal Seminar Series on Drug Discovery Budapest 5 January 2018 Macrophages: Professional phagocytes of the myeloid lineage APC,
CURRICULUM VITAE 53 YEARS IN SCIENCE
ROBERT M. HOFFMAN CURRICULUM VITAE 53 YEARS IN SCIENCE June 2018 :\\wpdocs\cv\rmh-cv_june 2018_cut-off Page 1 CURRICULUM VITAE ROBERT M. HOFFMAN OFFICES: AntiCancer, Inc. 7917 Ostrow Street San Diego,
Cancer Metastasis Directly Eradicated by Targeted Therapy With a Modified Salmonella typhimurium
ARTICLE Journal of Cellular Biochemistry 106:992 998 (2009) Journal of Cellular Biochemistry Cancer Metastasis Directly Eradicated by Targeted Therapy With a Modified Salmonella typhimurium Katsuhiro Hayashi,
Lecture 1: Carcinogenesis
Lecture 1: Carcinogenesis Anti-cancer (oncology agents): These are perhaps the most dangerous of drugs, other than the narcotic analgesics. This is due to their toxicities. Killing or inhibiting cancer
Team Progress Updates. SU2C Pancreatic Dream Team: Cutting Off the Fuel Supply: A New Approach in the Treatment of Pancreatic Cancer
SU2C Pancreatic Dream Team: Cutting Off the Fuel Supply: A New Approach in the Treatment of Pancreatic Cancer Cancer of the pancreas is one of the deadliest forms of cancer, with a five-year survival rate
International Graduate Research Programme in Cardiovascular Science
1 International Graduate Research Programme in Cardiovascular Science This work has been supported by the European Community s Sixth Framework Programme under grant agreement n LSHM-CT-2005-01883 EUGeneHeart.
Rob Glynne-Jones Mount Vernon Cancer Centre
ESMO Preceptorship Programme Colorectal Cancer Barcelona October 2017 Interventional radiology and stereotactic radiotherapy Rob Glynne-Jones Mount Vernon Cancer Centre My Disclosures: last 5 years Speaker:
Radiation Treatment for Breast. Cancer. Melissa James Radiation Oncologist August 2015
Radiation Treatment for Breast Cancer Melissa James Radiation Oncologist August 2015 OUTLINE External Beam Radiation treatment. (What is Radiation, doctor?) Role of radiation. (Why am I getting radiation,
Evolution at Its Worst: Cancer. SHP-Neurobiology of Development and Disease
Evolution at Its Worst: Cancer SHP-Neurobiology of Development and Disease Introduction to Cancer Cancer is currently the second leading cause of death in the US (22.8%) behind heart disease. Yearly 0.5%
PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland
AD Award Number: W81XWH-04-1-0618 TITLE: Are Breast Tumor Stem Cells Responsible for Metastasis and Angiogenesis PRINCIPAL INVESTIGATOR: Quintin Pan, Ph.D. CONTRACTING ORGANIZATION: University of Michigan
sensors ISSN by MDPI
Sensors 2008, 8, 1157-1173 Review sensors ISSN 1424-8220 2008 by MDPI www.mdpi.org/sensors Imaging In Mice With Fluorescent Proteins: From Macro To Subcellular Robert M. Hoffman AntiCancer, Inc., 7917
CRIPTO-1 A POSSIBLE NEW BIOMARKER IN GLIOBLASTOMA MULTIFORME PIA OLESEN, MD, PHD STUDENT
CRIPTO-1 A POSSIBLE NEW BIOMARKER IN GLIOBLASTOMA MULTIFORME PIA OLESEN, MD, PHD STUDENT Glioblastoma WHO Grade IV Glioma Heterogenic Undiffenrentiated phenotype 50% of all Gliomas Around 600 patients
Our laboratory pioneered the patient-derived orthotopic ARTICLE
ARTICLE Journal of Cellular Biochemistry 118:2314 2319 (2017) Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft
RIP-Tag2 mouse model as a Paradigm for Target. Search in NETs
RIP-Tag2 mouse model as a Paradigm for Target Search in NETs Oriol Casanovas, Ph.D. Tumor Angiogenesis Group INSTITUT CATALÀ d ONCOLOGIA IDIBELL Barcelona (SPAIN) Therapeutic Targeting of the Tumor Stroma
Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy
Paracrine Mechanisms in Adult Stem Cell Signaling and Therapy Massimiliano Gnecchi, Zhiping Zhang, Aiguo Ni, Victor J. Dzau Circulation Research 2008 Nov 21;103(11):1204-19 Introduction(1) After AMI all
Inflammatory Cells and Metastasis
Inflammatory Cells and Metastasis Experimentelle Krebsforschung SS 07 Gerhard Christofori Institute of Biochemistry and Genetics Department of Clinical-Biological Sciences Center of Biomedicine University
In vivo imaging with fluorescent proteins: the new cell biology $
Acta histochemica 106 (2004) 77 87 www.elsevier.de/acthis In vivo imaging with fluorescent proteins: the new cell biology $ Robert M. Hoffman* AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA 92111,
Research Article. Abstract. Introduction. Materialsand Methods
Research Article Development of Real-time Subcellular Dynamic Multicolor Imaging of Cancer-Cell Trafficking in Live Mice with a Variable-Magnification Whole-Mouse Imaging System Kensuke Yamauchi, 1,2,3
Applications. in Oncology
Kewal K. Jain Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Kewal K. Jain, MD, FRACS, FFPM Jain PharmaBiotech, Basel, Switzerland
ASSOCIATION FOR ACADEMIC SURGERY, Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model 1
Journal of Surgical Research 147, 276 281 (2008) doi:10.1016/j.jss.2007.04.021 ASSOCIATION FOR ACADEMIC SURGERY, 2004 Characterization of HCT116 Human Colon Cancer Cells in an Orthotopic Model 1 Ashwani
Oncolytic Viruses: Reovirus
T S X : O N C N A S D A Q : O N C Y International Society for Biological Therapy of Cancer 2008 Oncology Biologics Development Primer Oncolytic Viruses: Reovirus REOLYSIN - mode of action REOLYSIN contains
New Biological and Immunological Therapies for Cancer
New Biological and Immunological Therapies for Cancer Sant P. Chawla, M.D., FRACP The Sarcoma Oncology Center, Santa Monica CA 90403 7 th International Conference on Drug Discovery &Therapy 1 Promising
Therapeutic ratio - An Overview. Past Present Future Prof Ramesh S Bilimaga
Therapeutic ratio - An Overview Past Present Future Prof Ramesh S Bilimaga Radiation Oncology Discipline of human medicine concerned with the generation, conservation and dissemination of knowledge concerning
Cell therapy: enhancing the therapeutic potential of cardiac progenitors for delivery post myocardial infarction. Rita Alonaizan
Cell therapy: enhancing the therapeutic potential of cardiac progenitors for delivery post myocardial infarction Rita Alonaizan Department of Physiology, Anatomy & Genetics St Catherine s College Supervisor:
Inhibition of E-Selectin or E-selectin together with CXCR4 Re-sensitizes Multiple Myeloma to Treatment
Inhibition of E-Selectin or E-selectin together with CXCR4 Re-sensitizes Multiple Myeloma to Treatment 1, Ph.D. Henna Bazai 1, Anita Sekula 1, William Fogler 2, Ted Smith 2, John Magnani 2 and Abdel Kareem
CHMP Oncology Working Party Workshop on: Histology Independent Indications in Oncology. Non-clinical models: Tumour Models - Proof of Concept
CHMP Oncology Working Party Workshop on: Histology Independent Indications in Oncology Non-clinical models: Tumour Models - Proof of Concept Edward C. Rosfjord Pfizer Worldwide R. & D. 14 December 2017
Development of Degradable Stealth Nanospheres for Controlled Delivery of Anticancer Drugs
Development of Degradable Stealth Nanospheres for Controlled Delivery of Anticancer Drugs Emmanuel. Akala, R.Ph., Ph.D. Department of Pharmaceutical Sciences School of Pharmacy First Generation Polymeric
Index. Surg Oncol Clin N Am 16 (2007) Note: Page numbers of article titles are in boldface type.
Surg Oncol Clin N Am 16 (2007) 465 469 Index Note: Page numbers of article titles are in boldface type. A Adjuvant therapy, preoperative for gastric cancer, staging and, 339 B Breast cancer, metabolic
Cerebral Parenchymal Lesions: I. Metastatic Neoplasms
Chapter 4 Cerebral Parenchymal Lesions: I. Metastatic Neoplasms After one has reasonably ruled out the possibility of a nonneoplastic diagnosis (see Chap. 3), one is left with considering a diagnosis of
A PHASE 1 STUDY OF TRC105 (ANTI- ADVANCED SOLID TUMORS
ASCO 2011 Abstract Number: 3073 A PHASE 1 STUDY OF TRC105 (ANTI- CD105 ANTIBODY) IN PATIENTS WITH ADVANCED SOLID TUMORS J. W. Goldman, M. S. Gordon, H. Hurwitz, R. Pili, D. S. Mendelson, B. J. Adams, D.
What Radiologists do?
Multimodality Imaging in Oncology 2018 March 5 th 9th Diagnostic Imaging in Oncology What Radiologists do? Chikako Suzuki, MD, PhD Department of Diagnostic Radiology, KS Solna Department of Molecular Medicine
CANCER 1.7 M 609,000 26% 15.5 M 73% JUST THE FACTS. More Than 1,100 Cancer Treatments in Clinical Testing Offer Hope to Patients
CANCER MEDICINES IN DEVELOPMENT 2018 REPORT JUST THE FACTS MORE THAN 1.7 M ESTIMATED NEW CASES OF CANCER IN 2018 IN THE UNITED STATES MORE THAN 609,000 U.S. CANCER DEATHS ARE EXPECTED IN 2018 SINCE PEAKING
Integrin v 3 targeted therapy for Kaposi s sarcoma with an in vitro evolved antibody 1
Integrin v 3 targeted therapy for Kaposi s sarcoma with an in vitro evolved antibody 1 CHRISTOPH RADER, 2 MIKHAIL POPKOV, JOHN A. NEVES, AND CARLOS F. BARBAS III 2 Department of Molecular Biology and The
BIT 120. Copy of Cancer/HIV Lecture
BIT 120 Copy of Cancer/HIV Lecture Cancer DEFINITION Any abnormal growth of cells that has malignant potential i.e.. Leukemia Uncontrolled mitosis in WBC Genetic disease caused by an accumulation of mutations
Unit 3. The notes from class contain the comprehensive information for exam 3. The textbook readings support the notes.
Unit 3 The notes from class contain the comprehensive information for exam 3. The textbook readings support the notes. Why do normal cells divide? Replacement Repair Growth Regeneration (Formation of sperm
CLINICAL UPDATE ON K-RAS
CLINICAL UPDATE ON K-RAS TARGETED THERAPY IN GASTROINTESTINAL CANCERS S. PA N T, 1 J. H U B B A R D, 2 E. M A RT I N E L L I, 3 A N D T. B E K A I I - S A A B 4 SELECTED HIGHLIGHTS 1 Department of Investigational
Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2
![Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2](/thumbs/88/116309357.jpg "Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2")
America, Hershey, PA Australia, Melbourne, VIC Europe, Munich info@vivopharm.com www.vivopharm.com Tissue Bladder Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance Tanaka H, Kono E, Tran CP, Miyazaki H, Yamashiro J, Shimomura T, Ladan F, Wada R, Huang
The Galectin-3 Inhibitor GR-MD-02 for Combination Cancer Immunotherapy
The Galectin-3 Inhibitor GR-MD-02 for Combination Cancer Immunotherapy Supplemental Information to Corporate Presentation February 6, 2018 NASDAQ: GALT www.galectintherapeutics.com 2018 2017 Galectin Therapeutics
Cancer and Cell Differentiation
Cancer and Cell Differentiation Recall The cell cycle consists of interphase, mitosis, and cytokinesis. Recall During S phase of interphase, the DNA is replicated to prepare for mitosis. Each daughter
T Cell Development. Xuefang Cao, MD, PhD. November 3, 2015
T Cell Development Xuefang Cao, MD, PhD November 3, 2015 Thymocytes in the cortex of the thymus Early thymocytes development Positive and negative selection Lineage commitment Exit from the thymus and
Chemokine Regulation of Oligodendrocyte Development in the Spinal Cord. Bob Avino Saint Louis University Senior Honors Thesis April 19, 2011
Chemokine Regulation of Oligodendrocyte Development in the Spinal Cord Bob Avino Saint Louis University Senior Honors Thesis April 19, 2011 Richard J. Miller, PhD Northwestern University Feinberg School
Endomagnetics: healthcare by sensing, moving and heating magnetic nanoparticles in the human body. Quentin Pankhurst
Endomagnetics: healthcare by sensing, moving and heating magnetic nanoparticles in the human body Quentin Pankhurst Deputy Director London Centre for Nanotechnology Outline Magnetic therapy through the
IVC History, Cancer Research
Riordan Clinic IVC Academy 5 IVC History, Cancer Research O (slides 41-80) Pharmacokinetics of Oral Vitamin C using Liposomal Form* To test whether plasma vitamin C levels, following oral doses in supplemented
PET IMAGING (POSITRON EMISSION TOMOGRAPY) FACT SHEET
Positron Emission Tomography (PET) When calling Anthem (1-800-533-1120) or using the Point of Care authorization system for a Health Service Review, the following clinical information may be needed to
XV Encuentro de Cooperación Farma-Biotech. Novel nanoconjugate for the targeted treatment of metastatic colorectal cancer
Novel nanoconjugate for the targeted treatment of metastatic colorectal cancer Madrid, 15 de noviembre de 2016 1 The Institutions Use of microbial and non-microbial platforms for the production of new