Principal Investigator: Lawrence H. Kushi, ScD Project Manager: Janise M. Kim Roh, MSW, MPH. Funded by the National Cancer Institute (R01 CA105274)
|
|
- Gerard Morris
- 5 years ago
- Views:
Transcription
1 Principal Investigator: Lawrence H. Kushi, ScD Project Manager: Janise M. Kim Roh, MSW, MPH Funded by the National Cancer Institute (R01 CA105274) Kaiser Permanente Research
2 Background 3.1 million breast cancer survivors in the United States Lack of information on how non-clinical factors may influence breast cancer prognosis World Cancer Research Fund s recent systematic review of the literature on food, nutrition and physical activity in breast cancer prognosis recommended: More and better scientific research is needed in order to make specific recommendations for breast cancer survivors. Few studies on the impact of neighborhood and contextual level characteristics on prognosis 2 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
3 Study Objectives Investigate the effects of lifestyle, contextual, and molecular factors on breast cancer prognosis. Focusing on Post-diagnosis lifestyle factors including diet, physical activity, and complementary and alternative medicine (CAM) Social and built environment characteristics Molecular and genetic factors, including tumor DNA methylation profiles, inflammatory markers, and vitamin D levels 3 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
4 The Setting: Kaiser Permanente One of the oldest and largest integrated health care delivery systems in the United States Provides health care to approximately 3.5 million members throughout Northern California About 30% of the population residing in the counties in which KPNC has a physical presence are members of KPNC 4 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
5 KPNC Service Area 5 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
6 Data Resources at Kaiser Permanente Completely electronic health record since 2004 from Epic Systems (Verona, WI) branded as KP HealthConnect TM Legacy databases from the mid-1990s with documentation of clinical encounters and prescription medications KPNC Cancer Registry: reports to the Bay Area and State of California Surveillance, Epidemiology, and End Results (SEER) Cancer Registries 6 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
7 Pathways Study: A Collaboration Roswell Park Cancer Institute, Buffalo, NY Genetic and molecular factors Site PI: Christine Ambrosone, PhD Cancer Prevention Institute of California, Fremont, CA Social and contextual factors Site PI: Scarlett Lin Gomez, PhD University of California, San Francisco Tumor DNA methylation Site PI: John Wiencke, PhD Zero Breast Cancer, San Rafael, CA Community perspectives Site PI: Janice Barlow, BSN, NP 7 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
8 Eligibility Kaiser Permanente Northern California member Recent diagnosis of invasive breast cancer (AJCC Stages I-IV) At least 21 years old No previous history of malignant cancer English, Spanish, Mandarin, or Cantonese speaking Live within a 65-mile radius of a Pathways Study field interviewer 8 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
9 Recruitment Rapid case ascertainment via daily query of KPNC pathology databases Recruitment period: January 2006 through May 2013 Mean time from date of diagnosis to enrollment: 2.1 months Eligible Participants based on Electronic Pathology and Clinical Records 10,897 (100%) Letter Sent or Contacted Us 10,835 (99%) Appointment Scheduled 4,924 (45%) ENROLLED 4,505 (91%) Doctor Refused 62 (1%) Refused or Ineligible 5,911 (55%) Not Enrolled 419 (9%) 9 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
10 Study Enrollment by Race/Ethnicity and Age at Diagnosis (n, %) Asian Black White Hispani c Other Total Age group (y) < (38.6) 92 (25.7) 450 (15.5) 196 (35.2) 31 (26.3) 992 (22.0) (33.9) 128 (35.8) 797 (27.5) 170 (30.5) 30 (25.4) 1,321 (29.3) (20.1) 91 (25.4) 941 (32.5) 110 (19.7) 36 (30.5) 1,294 (28.7) (7.4) 47 (13.1) 706 (24.4) 81 (14.5) 21 (17.8) 898 (19.9) Total 578 (12.8) 358 (7.9) 2,894 (64.2) 557 (12.4) 118 (2.6) 4, April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
11 Study Enrollment by Race/Ethnicity and Body Mass Index (n, %) Asian Black White Hispanic Other Total Body Mass Index (kg/m 2 ) < (2.4) 0 (0.0) 29 (1.0) 3 (0.5) 1 (0.8) 47 (1.0) (50.7) 55 (15.4) 941 (32.5) 136 (24.4) 30 (25.4) 1,455 (32.3) (32.7) 88 (24.6) 919 (31.8) 191 (34.3) 36 (30.5) 1,423 (31.6) (9.3) 94 (26.3) 548 (18.9) 119 (21.4) 26 (22.0) 841 (18.7) (4.8) 121 (33.8) 456 (15.8) 108 (19.4) 25 (21.2) 738 (16.4) Total 578 (12.8) 358 (7.9) 2,894 (64.2) 557 (12.4) 118 (2.6) 4, April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
12 Selected Cohort Characteristics Distribution of AJCC Stage by Race/Ethnicity Stage I Stage II Stage III Stage IV Asian Black White Hispanic Other 12 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
13 Selected Cohort Characteristics Receptor Status by Race/Ethnicity Asian Black White Hispanic Other ER+ Triple Negative Status 13 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
14 Data Collection Timeline and Domains BL 14 April 30, Kaiser Foundation Health Plan, Inc. For internal use only. 6 Mo 12 Mo 24 Mo 48 Mo 72 Mo 96 Mo Demographics, Health History x Medical Conditions/Health Issues (Self-Reported) x x x x x Recurrence/New Cancers (Self-Reported) x x x x x Vitamins and Supplements x x x x Complementary and Alternative Medicine (CAM) x x x x Diet (including organic foods) x x x x Physical Activity x x x x Lymphedema x x x x Neighborhood Characteristics x Quality of Life & Psychosocial Measures x x x x Anthropometry Measures x x x x
15 Biorepository at RPCI Overall Collected Not Collected Blood 4,034 (89.5%) 388 (10.9%) Saliva 4,310 (95.7%) 195 (4.3%) Per Subject Blood Storage container Aliquot volume (ml) No. of aliquots Total volume (ml) Storage Temperature ( o C) Whole blood Cryovials Clot Cryovials Red cells Cryovials CBS Straws Plasma CBS Straws Serum CBS Straws Buffy coat CBS Straws Cryovials 0.5 as available -80 Saliva Oragene kit Room 15 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
16 Outcomes Ascertainment Self-Report from Questionnaires Report from Family Members KPNC Cancer Registry KPNC Mortality File Electronic Medical Record All potential outcomes confirmed via medical records review 16 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
17 Outcomes, as of December 31, 2014 (n, %) Breast Cancer Recurrence 369 (8.2) Second Primary Cancer 213 (4.7) Deaths 469 (10.4) Deaths due to Breast Cancer 214 (4.8) Breast Cancer-Free Survival* 483 (10.7) Invasive Disease-Free Survival 751 (16.7) Total recurrence, contralateral second primary invasive breast cancer (excludes new primary DCIS), or breast cancer death Total recurrence, invasive second primary cancer (excludes new primary DCIS), or total deaths 17 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
18 Preliminary Outcome Analyses Variable Race/Ethnicity (ref=white) 18 April 30, Kaiser Foundation Health Plan, Inc. For internal use only. Recurrence (n=369) Death (n=469) HR 95% CI HR 95% CI African American Hispanic Asian AJCC Stage (ref=i) II III IV ER status (ref=positive) negative Age-adjusted proportional hazards models
19 Preliminary Outcome Analyses Variable Recurrence (n=369) Death (n=469) HR 95% CI HR 95% CI BMI (ref= kg/m 2 ) < Age-adjusted proportional hazards models 19 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
20 Preliminary Outcome Analyses Variable Recurrence (n=369) Death (n=469) HR 95% CI HR 95% CI Total physical activity, MET-hrs/week (ref=low) medium high Moderate-vigorous activity, MET-hrs/week (ref=low) medium high Age-adjusted proportional hazards models 20 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
21 Pathways Ancillary Studies Racial Disparities in the Initiation and Intensity of Adjuvant Therapy for Breast Cancer (DOD BC043120; Pl: Al Neugut, Columbia University) Natural History and Cost Analysis of Lymphedema Secondary to Breast Cancer (ACS RSG LR; PI: Marilyn Kwan, KPNC) Using Physiological Age to Predict Chemotherapy Toxicity (R01 CA124924; PI: Jeanne Mandelblatt, Georgetown University) Adjuvant Breast Cancer Therapies: Race, Variations in Care and Survival (ACS RSGT , PI: Dawn Hershman, Columbia University) Lifestyle and Molecular Factors of Bone Health in Breast Cancer Survivors (R01 CA166701; Multiple PIs: Marilyn Kwan, KPNC, and Song Yao, Roswell Park Cancer Institute) 21 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
22 Next Steps Continue to build the Pathways Study resource Cohort follow-up through 96 months and annually thereafter Collect follow-up blood samples Obtain and store tumor specimens Linkage with contextual databases 22 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
23 Acknowledgements Principal Investigator Lawrence H. Kushi, ScD Co-Investigators Marilyn L. Kwan, PhD Lou Fehrenbacher, MD Susan Kutner, MD Bette Caan, DrPH Charles Quesenberry, PhD Barbara Sternfeld, PhD Carol Somkin, PhD Roswell Park Cancer Institute Christine Ambrosone, PhD Song Yao, PhD Chi-Chen Hong, PhD Cancer Prevention Institute of California Scarlett Lin Gomez, PhD Peggy Reynolds, PhD Theresa Keegan, PhD Salma Shariff-Marco, PhD University of California, San Francisco John Wiencke, PhD Shichun Zheng, MD Zero Breast Cancer Janise Barlow, BSN, NP Catherine Thomsen, MPH Research Team Isaac Ergas, MPH Cecile Laurent, MA Valerie Lee, MSPH Julie Munneke Judy Jensen Adriana Martinez Elinette Nicolas Julie Pham Virginia Pozo Claudia Samayoa Veronica Ting All Pathways Study participants 23 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
24 Thank You! 24 April 30, Kaiser Foundation Health Plan, Inc. For internal use only.
Changes in vitamin and mineral supplement use after breast cancer diagnosis in the Pathways Study: a prospective cohort study
Greenlee et al. BMC Cancer 2014, 14:382 RESEARCH ARTICLE Open Access Changes in vitamin and mineral supplement use after breast cancer diagnosis in the Pathways Study: a prospective cohort study Heather
More informationUC Office of the President Recent Work
UC Office of the President Recent Work Title The California Breast Cancer Survivorship Consortium (CBCSC): prognostic factors associated with racial/ethnic differences in breast cancer survival Permalink
More informationWellness Coaching for People with Prediabetes
Wellness Coaching for People with Prediabetes PUBLIC HEALTH RESEARCH, PRACTICE, AND POLICY Volume 12, E207 NOVEMBER 2015 ORIGINAL RESEARCH Wellness Coaching for People With Prediabetes: A Randomized Encouragement
More informationNIH Public Access Author Manuscript Breast Cancer Res Treat. Author manuscript; available in PMC 2012 February 5.
NIH Public Access Author Manuscript Published in final edited form as: Breast Cancer Res Treat. 2011 November ; 130(1): 195 205. doi:10.1007/s10549-011-1557-4. Multivitamin Use and Breast Cancer Outcomes
More informationSanta Clara County Highlights
Santa Clara County Highlights Data and Partnerships: Pivotal Elements to Create Healthy Communities November 6th, 2009 David Hill, PhD, MPH Cities of Santa Clara County 2 The pivotal elements Data evidence-based
More informationScarlett Gomez, MPH, PhD Cancer Prevention Institute of California NAACCR 2017 conference, Albuquerque NM June 2017
The influence of socioeconomic status and ethnic enclave on endometrial cancer mortality among Hispanic and Asian American/Pacific Islander women in California Scarlett Gomez, MPH, PhD Cancer Prevention
More informationSurvival among Native American Adolescent and Young Adult Cancer Patients in California
Survival among Native American Adolescent and Young Adult Cancer Patients in California Cyllene R. Morris, 1 Yi W. Chen, 1 Arti Parikh-Patel, 1 Kenneth W. Kizer, 1 Theresa H. Keegan 2 1 California Cancer
More informationCervical Cancer Screening and Prevention in Latinas. Sandra Torrente, MD, MSc Kenneth Grullon, MD
ç Cervical Cancer Screening and Prevention in Latinas Sandra Torrente, MD, MSc Kenneth Grullon, MD Objectives Cervical cancer epidemiology Cervical cancer screening rates locally Health Disparities of
More informationRacial and Ethnic Inequalities in Dementia: What Can We Learn from a Healthcare System Cohort?
Racial and Ethnic Inequalities in Dementia: What Can We Learn from a Healthcare System Cohort? Elizabeth Rose Mayeda, PhD, MPH Postdoctoral Fellow Department of Epidemiology and Biostatistics University
More informationData Issues in Studying Small Populations Challenges, Opportunities, and a Case Study
Data Issues in Studying Small Populations Challenges, Opportunities, and a Case Study Scarlett Lin Gomez, MPH, PhD Department of Epidemiology & Biostatistics, University of California, San Francisco A
More informationFinal Report 22 January 2014
Final Report 22 January 2014 Cohort Study of Pioglitazone and Cancer Incidence in Patients with Diabetes Mellitus, Follow-up 1997-2012 Kaiser Permanente Division of Research Assiamira Ferrara, MD, Ph.D.
More informationCommunity Participation in Cancer Discovery Research: Linking Biology, Cancer Disparities, and Dissemination
Community Participation in Cancer Discovery Research: Linking Biology, Cancer Disparities, and Dissemination Robert A. Hiatt UCSF Helen Diller Family Comprehensive Cancer Center July 13, 2011 Bethesda,
More information/RFDO )LQGLQJV. Cancers All Types. Cancer is the second leading cause of death in Contra Costa.
Cancers All Types Cancer is the second leading cause of death in Contra Costa. Deaths Contra Costa s cancer death rate (170.5 per 100,000) does not meet the national Healthy People 2010 objective (159.9
More informationMelanoma Survivors: Health Behaviors, Surveillance, Psychosocial Factors, and Family Concerns Pilot Study
Melanoma Survivors: Health Behaviors, Surveillance, Psychosocial Factors, and Family Concerns Pilot Study Susan A. Oliveria, ScD, MPH Dermatology Service / Department of Medicine Memorial Sloan-Kettering
More informationLinking Oncotype Dx results to SEER data and patient report to assess challenges in individualizing breast cancer care
Linking Oncotype Dx results to SEER data and patient report to assess challenges in individualizing breast cancer care June 16, 2015 NAACCR, Charlotte, NC Ann Hamilton, Ph.D. Keck School of Medicine, University
More informationPCPT and SELECT Cancer Cohorts
PCPT and SELECT Cancer Cohorts Briefly describe PCPT and SELECT trial designs Current follow-up status for each cohort SELECT Centralized Follow-up Data elements and biologic samples collected Events ascertained,
More informationCancer Prevention Institute of California, Fremont, California. 2. Stanford Cancer Institute, Stanford, California. 3
How much of the racial/ethnic disparities in cancer survival in California is explained by differences in tumor, sociodemographic, institutional and neighborhood characteristics? Elizabeth Ellis 1,2, Alison
More informationRacial/Ethnic Disparities in Second Breast Lesions after DCIS. Graham A. Colditz, MD DrPH Kevin Garza Ying Liu, MD PhD Rosy Luo, PhD Yu Tao, PhD
Racial/Ethnic Disparities in Second Breast Lesions after DCIS Graham A. Colditz, MD DrPH Kevin Garza Ying Liu, MD PhD Rosy Luo, PhD Yu Tao, PhD Why DCIS? DCIS over 45,000 cases per year SEER 18 Cancer
More informationChapter 5: Epidemiology of MBC Challenges with Population-Based Statistics
Chapter 5: Epidemiology of MBC Challenges with Population-Based Statistics Musa Mayer 1 1 AdvancedBC.org, Abstract To advocate most effectively for a population of patients, they must be accurately described
More informationDiagnosis and Treatment of Neuropathy Post Chemotherapy in Three Health Care Systems
Diagnosis and Treatment of Neuropathy Post Chemotherapy in Three Health Care Systems HCSRN 2019 Conference April 10, 2019 Kaiser Permanente Research Peripheral neuropathy is a common side effect of neurotoxic
More informationThe Breast Cancer and Environment Research Centers: Experience and Plans
The Breast Cancer and Environment Research Centers: Experience and Plans Institute of Medicine Committee on Breast Cancer and the Environment July 7, 2010 San Francisco, CA Purpose of the Breast Cancer
More informationThe contribution of the population biobank of ISPO
The contribution of the population biobank of ISPO Domenico Palli Molecular and Nutritional Epidemiology Unit - ISPO, Florence d.palli@ispo.toscana.it 9 March 2012, Rome Challenges and Opportunities of
More informationChanging Incidence of Hodgkin Lymphoma Histologic Subtypes: Risk Factor Trends or Evolving Diagnostic Practice?
Changing Incidence of Hodgkin Lymphoma Histologic Subtypes: Risk Factor Trends or Evolving Diagnostic Practice? Greater Bay Area Cancer Registry Cancer Prevention Institute of California Stanford Cancer
More informationHypertension Update 2014:
GSHTP Webinar Hypertension Update 2014: The Kaiser Permanente Northern California Experience Presented by: Marc Jaffe, MD Associate Clinical Professor of Medicine, UCSF Kaiser Permanente Northern California
More informationEnhancing Breast Cancer Recurrence Algorithms Through Selective Use of Medical Record Data
JNCI J Natl Cancer Inst (2016) 108(3): djv336 doi:10.1093/jnci/djv336 First published online November 18, 2015 Article Enhancing Breast Cancer Recurrence Algorithms Through Selective Use of Medical Record
More informationTheresa Keegan, Ph.D., M.S. Associate Professor Department of Internal Medicine Division of Hematology and Oncology
Impact of treatment and insurance on socioeconomic disparities in survival after adolescent and young adult Hodgkin lymphoma: A population- based study Theresa Keegan, Ph.D., M.S. Associate Professor Department
More informationHypertension and diabetes treatments and risk of adverse outcomes among breast cancer patients. Lu Chen
Hypertension and diabetes treatments and risk of adverse outcomes among breast cancer patients Lu Chen A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy
More informationCharacteristics of Philadelphia Census Tracts with High Prostate Cancer Risk
Characteristics of Philadelphia Census Tracts with High Prostate Cancer Risk Charnita Zeigler-Johnson, PhD, MPH Thomas Jefferson University Philadelphia, PA Using Cancer Registry Data in Disparities Research
More informationThe Multiethnic Cohort Study: Studying Ethnic Diversity and Cancer. Laurence N. Kolonel, MD, PhD
The Multiethnic Cohort Study: Studying Ethnic Diversity and Cancer Laurence N. Kolonel, MD, PhD Background of the Multiethnic Cohort Study (MEC) Features of the Design Multiethnic: Five groups in Hawaii
More informationCHRONIC HEPATITIS B AND C COHORT STUDY (CHECS)
CHRONIC HEPATITIS B AND C COHORT STUDY (CHECS) CDC CONTACT Scott D Holmberg, M.D., M.P.H. Chief, Epidemiology and Surveillance Branch Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis,
More informationThe Breast Cancer Weight Loss (BWEL) Trial
Plenary Session: Integrative Innovations in Digital Health Technologies with Cancer Patients and Survivors The Breast Cancer Weight Loss (BWEL) Trial Jennifer Ligibel, MD Dana-Farber Cancer Institute SIO
More informationAYA HOPE: A Population-based Cohort Study of Adolescent and Young Adults with Cancer. Linda Harlan, PhD, MPH, BSN National Cancer Institute
AYA HOPE: A Population-based Cohort Study of Adolescent and Young Adults with Cancer Linda Harlan, PhD, MPH, BSN National Cancer Institute Funded by: National Cancer Institute with support from the LIVESTRONG
More informationType 2 Diabetes in Native Hawaiians according to Admixture: The Multiethnic Cohort
Type 2 Diabetes in Native Hawaiians according to Admixture: The Multiethnic Cohort Gertraud Maskarinec, Yukiko Morimoto, Simone Jacobs, Andrew Grandinetti, Marjorie Mau, Laurence N. Kolonel Prevalence
More informationExamining Subsequent Occurrence and Outcomes of Estrogen-related Cancers (Breast and Thyroid) in Missouri Women
Examining Subsequent Occurrence and Outcomes of Estrogen-related Cancers (Breast and Thyroid) in Missouri Women Iris Zachary, PhD, MSHI, CTR; Jeannette Jackson-Thompson, MSPH, PhD; Chester Schmaltz, PhD
More informationintegrating Data for Analysis, Anonymization, and SHaring
integrating Data for Analysis, Anonymization, and SHaring Informed Consent for Biospecimen Collection and Data Sharing among Low-income, Uninsured and Underinsured Women: Is it a Matter of Trust? Maria
More informationFunded by National Cancer Institute - 5 R01 CA
UNC-Chapel Hill Sam Cykert, MD, Co-PI Geni Eng, DrPH, Co-PI Christina Y. Hardy, MPH, Project Manager Alexandra Lightfoot, EdD, Process Evaluator Ziya Gizlice, PhD, Biostatistician Brian Cass, MS, Informatics
More informationShort Term Cancer Risk
in a Cohort of 2312 Women with High Risk Breast Lesions Kubat E 1, Puligandla B 2, Collins L 3, Jiang SF 4, Callahan M 5, Kutner S 6, Habel L 4, Shim V 1 1 Surgery, Kaiser Permanente, Oakland, CA; 2 Pathology,
More informationObesity and Breast Cancer Risk in Hispanics: Findings from the Breast Cancer Health Disparities Study
Obesity and Breast Cancer Risk in Hispanics: Findings from the Breast Cancer Health Disparities Study Esther M. John, PhD, MSPH Senior Research Scientist Cancer Prevention Institute of California AICR
More informationIdentifying Geographic & Socioeconomic Disparities in Access to Care for Pediatric Cancer Patients in Texas
Identifying Geographic & Socioeconomic Disparities in Access to Care for Pediatric Cancer Patients in Texas Mary T. Austin, MD, MPH Assistant Professor, Pediatric Surgery University of Texas Health Science
More informationBreast Cancer in Childhood Cancer Survivors: The Impact of Screening on Morbidity
Breast Cancer in Childhood Cancer Survivors: The Impact of Screening on Morbidity WORKING GROUP: This report will be written within the Cancer Control Working Group with oversight from the Second Malignant
More informationPhysical activity, Obesity, Diet and Colorectal Cancer Prognosis. Jeffrey Meyerhardt, MD, MPH Dana-Farber Cancer Institute Boston, MA
Physical activity, Obesity, Diet and Colorectal Cancer Prognosis Jeffrey Meyerhardt, MD, MPH Dana-Farber Cancer Institute Boston, MA Colorectal Cancer Incidence ~148,000 cases in US annually and ~50,000
More informationMinneapolis Department of Health and Family Support HIV Surveillance
Rate per 1, persons 2 21 22 23 24 25 26 27 28 29 21 Rate per 1, persons Minneapolis Department of Health and Family Support HIV Surveillance Research Brief, September 212 Human immunodeficiency virus (HIV)
More informationHow Are We Doing with Cervical Cancer Screening in the U.S.?
How Are We Doing with Cervical Cancer Screening in the U.S.? Vicki Benard, PhD Chief, Cancer Surveillance Branch Center for Disease Control and Prevention Atlanta, GA Disclosures No financial relationships
More informationTITLE: Vitamin D, Vitamin D Receptor Polymorphisms and Breast Cancer Aggressiveness in African American and European American Women
AD Award Number: W81XWH-08-1-0223 TITLE: Vitamin D, Vitamin D Receptor Polymorphisms and Breast Cancer Aggressiveness in African American and European American Women PRINCIPAL INVESTIGATOR: Song Yao CONTRACTING
More informationPhysician Follow-Up and Guideline Adherence in Post- Treatment Surveillance of Colorectal Cancer
Physician Follow-Up and Guideline Adherence in Post- Treatment Surveillance of Colorectal Cancer Gabriela M. Vargas, MD Kristin M. Sheffield, PhD, Abhishek Parmar, MD, Yimei Han, MS, Kimberly M. Brown,
More informationBreast Cancer: Weight and Exercise. Anne McTiernan, MD, PhD. Fred Hutchinson Cancer Research Center Seattle, WA
Breast Cancer: Weight and Exercise Anne McTiernan, MD, PhD Fred Hutchinson Cancer Research Center Seattle, WA Associations of Obesity with Overall & Breast Cancer Specific Survival Survival Obese vs. Non-obese
More informationIncidence of Surgically Treated Benign Prostatic Hypertrophy and of Prostate Cancer among Blacks and Whites in a Prepaid Health Care Plan
American Journal of EpKtermotogy Vo! 134, No 8 Copyright C 1991 by The Johns Hopkrts Uruversfty School of Hygiene and Put*: Health Printed in US A AS rights reserved A BRIEF ORIGINAL CONTRIBUTION Incidence
More informationBreast Cancer Subtypes Defined by HR/HER2 among Black Cases in the US by Birthplace
NAACCR 2018 Annual Conference Breast Cancer Subtypes Defined by HR/HER2 among Black Cases in the US by Birthplace Hyuna Sung, PhD; Carol Desantis, MPH; Stacey Fedawa, PhD; Ahmedin Jemal, DVM, PhD Surveillance
More informationSurgical Management of Metastatic Colon Cancer: analysis of the Surveillance, Epidemiology and End Results (SEER) database
Surgical Management of Metastatic Colon Cancer: analysis of the Surveillance, Epidemiology and End Results (SEER) database Hadi Khan, MD 1, Adam J. Olszewski, MD 2 and Ponnandai S. Somasundar, MD 1 1 Department
More informationTrends in Basal Cell Carcinoma Incidence and Identification of High-Risk Subgroups,
Research Original Investigation Trends in Basal Cell Carcinoma Incidence and Identification of High-Risk Subgroups, 1998-2012 Maryam M. Asgari, MD, MPH; Howard H. Moffet, MPH; G. Thomas Ray, MBA; Charles
More informationSTD/HIV Program Update
Department of Health and Human Services Olivia Kasirye MD, MS Public Health Officer Reportable STDs Bacterial Chlamydia Gonorrhea Syphilis Viral HIV/AIDS Hepatitis B Hepatitis C December 8, 2015 2 Five
More informationCenters for Disease Control and Prevention (CDC)
American Cancer Society Ahmedin Jemal, DVM, PhD; Helmneh M. Sineshaw, MD, MPH Centers for Disease Control and Prevention (CDC) Manxia Wu, MD, MPH Florida Cancer Data System Brad Alan Wohler-Torres, MSc
More informationDiversity and Dementia
Diversity and Dementia Kala M. Mehta, DSc, MPH January 17, 2012 Overview Background Incidence and Prevalence of Dementia Why are these differences found? What s important for diverse dementia patients
More information6/20/2012. Co-authors. Background. Sociodemographic Predictors of Non-Receipt of Guidelines-Concordant Chemotherapy. Age 70 Years
Sociodemographic Predictors of Non-Receipt of Guidelines-Concordant Chemotherapy - among Locoregional Breast Cancer Patients Under Age 70 Years Xiao-Cheng Wu, MD, MPH 2012 NAACCR Annual Conference June
More informationExercise Behavior & Major Cardiac Events: CCSS 1 STUDY TITLE
STUDY TITLE Exercise Behavior & Major Cardiac Events: CCSS 1 Association Between Exercise Behavior and Incidence of Major Cardiac Events in Adult Survivors of Childhood Cancer: A Report from the Childhood
More informationTreatment disparities for patients diagnosed with metastatic bladder cancer in California
Treatment disparities for patients diagnosed with metastatic bladder cancer in California Rosemary D. Cress, Dr. PH, Amy Klapheke, MPH Public Health Institute Cancer Registry of Greater California Introduction
More informationPublic-Private Collaboration to Re-engage Out-of-Care Persons into HIV Care
Public-Private Collaboration to Re-engage Out-of-Care Persons into HIV Care Chi-Chi Udeagu, MPH Jamie Huang, MPH Lil Eason Leonard Pickett New York City Department of Health and Mental Hygiene Adherence
More informationAmerican Cancer Society Progress Report. December 2016
American Cancer Society Progress Report December 2016 2015 Goals Incidence: By 2015, 25% reduction (unlikely to meet goal) Baseline 1992-2013: 12.1% reduction Latest joinpoint trend: -1.5% APC (2009-2013)
More informationSurveillance Research Program: Innovation, Impact and Productivity
Greater Bay Area Cancer Registry Surveillance Research Program: Innovation, Impact and Productivity Sally L. Glaser, Ph.D., GBACR PI Christina A. Clarke, Ph.D., GBACR Co-I Scarlett Lin Gomez, Ph.D., GBACR
More information4/13/2010. Silverman, Buchanan Breast, 2003
Tailoring Breast Cancer Treatment: Has Personalized Medicine Arrived? Judith Luce, M.D. San Francisco General Hospital Avon Comprehensive Breast Care Center Outline First, treatment of DCIS Sorting risk
More informationParental Perception of Quality of Hospital Care for Children with Sickle Cell Disease
Parental Perception of Quality of Hospital Care for Children with Sickle Cell Disease Jared Kam, BS; Julie A. Panepinto, MD, MSPH; Amanda M. Brandow, DO; David C. Brousseau, MD, MS Abstract Problem Considered:
More informationProvincial Survivorship Forum 2014
Provincial Survivorship Forum 2014 Dr. Frances Wong BCCA-Fraser Valley Centre September 22, 2014 From diagnosis until end of life Diagnosis and Staging Treatment with Intent to Cure Palliative Treatment
More informationCrossing the Chasm in Equity: Eliminating Health Care Disparities
Crossing the Chasm in Equity: Eliminating Health Care Disparities Winston F Wong, MD, MS Medical Director, National Program Offices Community Benefit March 25, 2010 Health is Rooted in Communities Our
More informationHEALTH PROMOTION AND CHRONIC DISEASE PREVENTION PROGRAM OREGON STATE OF THE HEART AND STROKE REPORT 2001 PREPARED BY.
OREGON STATE OF THE HEART AND STROKE REPORT 2001 PREPARED BY THE OREGON DEPARTMENT OF HUMAN SERVICES HEALTH SERVICES HEALTH PROMOTION AND CHRONIC DISEASE PREVENTION PROGRAM www.healthoregon.org/hpcdp Contents
More informationObesity and Breast Cancer in a Multiethnic Population. Gertraud Maskarinec, MD, PhD University of Hawaii Cancer Center, Honolulu, HI
Obesity and Breast Cancer in a Multiethnic Population Gertraud Maskarinec, MD, PhD University of Hawaii Cancer Center, Honolulu, HI Background Breast cancer incidence remains lower in many Asian than Western
More informationPopulation-based Patterns of HIV-related Hodgkin Lymphoma in the Greater San Francisco Bay Area:
Population-based Patterns of HIV-related Hodgkin Lymphoma in the Greater San Francisco Bay Area: 1988-98 Sally Glaser, Ph.D. Christina Clarke, Ph.D. Northern California Cancer Center Margaret Gulley, M.D.
More informationChlamydia, Gonorrhea, Disparities: A National Perspective (anything else?) Catherine Lindsey Satterwhite Region IV IPP Meeting October 8, 2009
Chlamydia, Gonorrhea, Disparities: A National Perspective (anything else?) Catherine Lindsey Satterwhite Region IV IPP Meeting October 8, 29 Outline Disease burden and disparities Morbidity data IPP data
More informationTable of Contents. 2 P age. Susan G. Komen
RHODE ISLAND Table of Contents Table of Contents... 2 Introduction... 3 About... 3 Susan G. Komen Affiliate Network... 3 Purpose of the State Community Profile Report... 4 Quantitative Data: Measuring
More informationDiabetes - Deaths African Americans and Latinos are more likely to die from diabetes than other Contra Costa residents.
Diabetes - Deaths African Americans and Latinos are more likely to die from diabetes than other Contra Costa residents. Diabetes is the seventh leading cause of death In Contra Costa, diabetes accounts
More informationBreast Cancer: Weight and Exercise. Anne McTiernan, MD, PhD. Fred Hutchinson Cancer Research Center Seattle, WA
Breast Cancer: Weight and Exercise Anne McTiernan, MD, PhD Fred Hutchinson Cancer Research Center Seattle, WA Associations of Obesity with Overall & Breast Cancer Specific Survival Survival Obese vs. Non-obese
More informationTime to Colonoscopy After a Positive Fecal Test and Risk of Colorectal Cancer Outcomes
Time to Colonoscopy After a Positive Fecal Test and Risk of Colorectal Cancer Outcomes Douglas Corley MD, PhD Kaiser Permanente, Northern California For Corley DA, Jensen CD, Quinn VP, Doubeni CA, Zauber
More informationUSING AN INTEGRATED APPROACH TO ASSESS HEPATITIS B VACCINATION AND IMMUNITY AMONG PEOPLE LIVING WITH HIV
USING AN INTEGRATED APPROACH TO ASSESS HEPATITIS B VACCINATION AND IMMUNITY AMONG PEOPLE LIVING WITH HIV Courtney Smith, MPH Wyoming Department of Health Background People with HIV are at an increased
More informationDisclosures. How to Become Even Better Allies 10/18/2016 LANGUAGE AND LITERACY THE PAS DE DEUX
Disclosures LANGUAGE AND LITERACY THE PAS DE DEUX Alicia Fernandez, MD Professor of Medicine University of California, San Francisco Zuckerberg San Francisco General NIH-NIDDK; NIMHD; NHLBI; Arnold P.
More information1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor Study.
CCSS Analysis Concept Proposal Exercise, Mortality, & Childhood Cancer 1 1. Study Title. Exercise and Late Mortality in 5-Year Survivors of Childhood Cancer: a Report from the Childhood Cancer Survivor
More informationTITLE: MicroRNA in Prostate Cancer Racial Disparities and Aggressiveness
AWARD NUMBER: W81XWH-13-1-0477 TITLE: MicroRNA in Prostate Cancer Racial Disparities and Aggressiveness PRINCIPAL INVESTIGATOR: Cathryn Bock CONTRACTING ORGANIZATION: Wayne State University REPORT DATE:
More informationPhysical Activity and Risk of Recurrence and Mortality in Breast Cancer Survivors: Findings from the LACE Study
87 Physical Activity and Risk of Recurrence and Mortality in Breast Cancer Survivors: Findings from the LACE Study Barbara Sternfeld, 1 Erin Weltzien, 1 Charles P. Quesenberry, Jr., 1 Adrienne L. Castillo,
More informationUse of Endocrine Therapy Data Points # 14
Use of endocrine therapy following diagnosis of ductal carcinoma in situ or early invasive breast cancer Use of Endocrine Therapy Data Points # 14 In 212, approximately 23, women in the United States were
More informationOUTCOME DISPARITIES BY AGE AND 21-GENE RECURRENCE SCORE RESULT IN HORMONE RECEPTOR-POSITIVE (HR+) BREAST CANCER
OUTCOME DISPARITIES BY AGE AND 21-GENE RECURRENCE SCORE RESULT IN HORMONE RECEPTOR-POSITIVE (HR+) BREAST CANCER Shak S, 1 Miller DP, 1 Howlader N, 2 Gliner N, 1 Howe W, 3 Schussler N, 3 Cronin K, 2 Baehner
More informationTable of Contents. 2 P age. Susan G. Komen
WYOMING Table of Contents Table of Contents... 2 Introduction... 3 About... 3 Susan G. Komen Affiliate Network... 3 Purpose of the State Community Profile Report... 4 Quantitative Data: Measuring Breast
More informationSalpingectomy for Sterilization
Salpingectomy for Sterilization Change in Practice in a Large Integrated Health Care System 2011-2016 Journal Club November 15, 2017 Blaine Campbell, DO Salpingectomy for Sterilization: Change in Practice
More informationMISSING IN ACTION : Ethnic Groups in Cancer Screening
MISSING IN ACTION : Ethnic Groups in Cancer Screening Annette E. Maxwell, Dr.P.H. Division of Cancer Prevention and Control Research Jonsson Comprehensive Cancer Center University of California, Los Angeles
More informationShort-term Navigation successful at re-engaging patients in care
Short-term Navigation successful at re-engaging patients in care IAPAC June 29, 2015 Darpun Sachdev, MD Sharon Pipkin, MPH Susan Scheer, PhD, MPH Stephanie Cohen, MD, MPH Erin Antunez, M.S. San Francisco
More informationNIH Public Access Author Manuscript Arch Dermatol. Author manuscript; available in PMC 2009 August 20.
NIH Public Access Author Manuscript Published in final edited form as: Arch Dermatol. 2009 August ; 145(8): 879 882. doi:10.1001/archdermatol.2009.176. Antioxidant Supplementation and Risk of Incident
More informationCohort Profile. 16 th October Dr. Tania Islam Department of Surgery Faculty of Medicine
Cohort Profile 16 th October 2017 Dr. Tania Islam Department of Surgery Faculty of Medicine Why was the cohort set up? In Malaysia, there is marked ethnic differences in breast cancer incidence, disease
More informationAdjuvant Hormonal Therapy for Breast Cancer and Risk of Hormone Receptor Specific Subtypes of Contralateral Breast Cancer
Published Online First on August 25, 2009 as 10.1158/0008-5472.CAN-09-1355 Adjuvant Hormonal Therapy for Breast Cancer and Risk of Hormone Receptor Specific Subtypes of Contralateral Breast Cancer Christopher
More informationThiazolidinediones and the risk of bladder cancer: A cohort study. R Mamtani, K Haynes, WB Bilker, DJ Vaughn, BL Strom, K Glanz, JD Lewis
Thiazolidinediones and the risk of bladder cancer: A cohort study R Mamtani, K Haynes, WB Bilker, DJ Vaughn, BL Strom, K Glanz, JD Lewis Study objective To investigate the risk of bladder cancer associated
More information8/10/2012. Education level and diabetes risk: The EPIC-InterAct study AIM. Background. Case-cohort design. Int J Epidemiol 2012 (in press)
Education level and diabetes risk: The EPIC-InterAct study 50 authors from European countries Int J Epidemiol 2012 (in press) Background Type 2 diabetes mellitus (T2DM) is one of the most common chronic
More informationTITLE: Breast Density Assessment by Dual Energy X-ray Absorptiometry in Women and Girls. Rachel Novotny, Ph.D. Honolulu, HI 96822
AD AWARD NUMBER: W81XWH-07-1-0489 TITLE: Breast Density Assessment by Dual Energy X-ray Absorptiometry in Women and Girls PRINCIPAL INVESTIGATOR: Gertraud Maskarinec, M.D., Ph.D. Rachel Novotny, Ph.D.
More informationPopulation Health Observatory
University at Buffalo The State University of New York School of Public Health and Health Professions Population Health Observatory Dedicated to improving health through population based research. community
More informationPrevalence of Overweight Among Anchorage Children: A Study of Anchorage School District Data:
Department of Health and Social Services Division of Public Health Section of Epidemiology Joel Gilbertson, Commissioner Richard Mandsager, MD, Director Beth Funk, MD, MPH, Editor 36 C Street, Suite 54,
More informationThe Use of Clinical Trial Data in Combination with External Data Sources to Examine Novel Cancer Research Questions: A Modified Big Data Approach
The Use of Clinical Trial Data in Combination with External Data Sources to Examine Novel Cancer Research Questions: A Modified Big Data Approach Joseph Unger, Ph.D. Assistant Member, Public Health Sciences
More informationPost-diagnosis quality of life and mortality in non- Hispanic White and Hispanic women diagnosed with invasive breast cancer.
University of Louisville ThinkIR: The University of Louisville's Institutional Repository Electronic Theses and Dissertations 8-218 Post-diagnosis quality of life and mortality in non- Hispanic White and
More informationTPMG experience in improving colorectal cancer screening rates
TPMG experience in improving colorectal cancer screening rates Theodore R. Levin, MD Clinical Lead for CRC screening, The Permanente Medical Group, Inc Kaiser Permanente Northern California Kaiser Permanente
More informationThe Cancer Burden in California. Janet Bates MD MPH California Cancer Registry California Department of Public Health April 25, 2012
The Cancer Burden in California Janet Bates MD MPH California Cancer Registry California Department of Public Health April 25, 2012 Goals Introduce you to the California Cancer Registry (CCR) Provide an
More informationSan Francisco Medical Monitoring Project (MMP) Maree Kay Parisi Applied Research, Community Health Epidemiology and Surveillance
San Francisco Medical Monitoring Project (MMP) Maree Kay Parisi Applied Research, Community Health Epidemiology and Surveillance Medical Monitoring Project Overview National prospective Local data and
More informationShu-Hong Zhu, PhD University of California, San Diego INTRODUCING THE ASIAN SMOKERS QUITLINE (ASQ)
Shu-Hong Zhu, PhD University of California, San Diego INTRODUCING THE ASIAN SMOKERS QUITLINE (ASQ) THE REACH AND EFFICACY OF A MULTILINGUAL TELEPHONE QUITLINE FOR ASIAN SMOKERS English Quitlines in 1992
More informationKAISER PERMANENTE ANNUAL CANCER REPORT 2016 MEDICAL CENTER SAN FRANCISCO THE PERMANENTE MEDICAL GROUP COMMISSION ON CANCER COMMITTEE DECEMBER 2016
1 KAISER PERMANENTE ANNUAL CANCER REPORT 2016 SAN FRANCISCO MEDICAL CENTER THE PERMANENTE MEDICAL GROUP COMMISSION ON CANCER COMMITTEE DECEMBER 2016 2 OUR MISSION IS SIMPLE: Support our specialists in
More informationTable of Contents. 2 P a g e. Susan G. Komen
NEW HAMPSHIRE Table of Contents Table of Contents... 2 Introduction... 3 About... 3 Susan G. Komen Affiliate Network... 3 Purpose of the State Community Profile Report... 4 Quantitative Data: Measuring
More informationPerceived Recurrence Risk and Health Behavior Change Among Breast Cancer Survivors
University of Massachusetts Amherst ScholarWorks@UMass Amherst Masters Theses 1911 - February 2014 2013 Perceived Recurrence Risk and Health Behavior Change Among Breast Cancer Survivors E Konieczny University
More informationRacial and Socioeconomic Disparities in Appendicitis
Racial and Socioeconomic Disparities in Appendicitis Steven L. Lee, MD Chief of Pediatric Surgery, Harbor-UCLA Associate Clinical Professor of Surgery and Pediatrics David Geffen School of Medicine at
More information