FALL MEETING. Sitges, 7th and 8th October, Venue. ME Sitges Terramar Hotel Passeig Marítim, Sitges, Barcelona

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1 FALL MEETING Sitges, 7th and 8th October, 2018 Venue ME Sitges Terramar Hotel Passeig Marítim, Sitges, Barcelona

2

3 Sunday 7 th October 2018 Time slot Topic / Title of presentation Chair Board meeting Arrivals & Welcome coffee Welcome & Introduction New Board, Previous minutes, Membership status, Calendar and publications/abstracts, Finances B. Besse, N.Reguart, J.Remon, B. Besse, S. Novello, A-M Dingemans Protocols in SCLC and Thymic Malignancies: 1417 (REACTION): A phase II study of etoposide and cis/carboplatin with or without pembrolizumab in untreated extensive small cell lung cancer B. Besse 1525 (NivoThym): Single-arm, multicenter, phase II study of immunotherapy in patients with type B3 thymoma and thymic carcinoma previously treated with chemotherapy N. Girard New proposals: - PRIMAlung C. Faivre-Finn, A. Levy Oligometastatic disease consensus: update Protocols in early stage, locally advanced and brain metastases NSCLC: N. Girard, Jessica Menis A-M Dingemans (HALT): Targeted therapy beyond progression with or without dose-intensified radiotherapy in oligoprogressive disease (OPD) in oncogene Addicted Lung Tumours M. guckenberger, N. Andratschke 1416 (PEARLS): A Randomized, Phase 3 Trial With Anti- PD-1 Monoclonal Antibody Pembrolizumab (MK-3475) Versus Placebo for Patients With Early Stage NSCLC After Resection and Completion of Standard Adjuvant Therapy (PEARLS)_ presenter? C. Faivre-Finn, J. Edwards, A. Levy

4 1807: Randomized phase II trials of early radiosurgery versus delayed radiosurgery or other salvage treatment (EVER) with either checkpoint inhibition (EVER-IO) or tyrosine kinase inhibitors (EVER-TKI) for the treatment of patients with brain metastases from non-small cell lung cancer (NSCLC) M. Guckenberger, N. Andratschke New Proposals: - SARON C. Faivre-Finn - Quality of life outcomes in patients with resectable N2 NSCLC undergoing surgery/chemotherapy versus radiotherapy/chemotherapy; a randomised controlled feasibility trial C. Faivre-Finn, J. Edwards - CONCORDE key points G. Hanna Lunch 14:40 15:10 Young Investigators Projects I L. Hendriks, M. Giaj Levra Protocols in advanced NSCLC: 1613 (APPLE): Feasibility and activity of AZD9291 (osimertinib) treatment on Positive PLasma T790M in EGFR mutant NSCLC patients - R. Dziadziuszko, J. Remon (SOLUTION): Randomized phase II study of durvalumab and tremelimumab combination versus standard of care following first-line platinum based chemotherapy in two cohorts of patients with nonsquamous and squamous NSCLC L. Hendriks 0811 (SPLENDOUR): A randomised, open-label phase III trial evaluating the addition of denosumab to standard first-line anticancer treatment in advanced NSCLC B. Besse, J. Corral Concepts: - ALKALINE - A-M Dingemans, L. Mezquita - Nivo in elderly patients - S. Novello, M. Giaj Levra New proposals: - PIEtrial G. Pasello

5 16:10 18:10 KEY Lectures 16:10-16:30 The role of the Spanish Medical Oncology Society (SEOM) in the European Oncology Community Ruth Vera 16:30-16:50 How do I foresee lung cancer treatment in the five years to come Luis Paz-Ares :10 Coffee break 17:10-17:30 Is it possible to improve patients outcomes in oligometastatic NSCLC with local therapy? Ramon Rami-Porta 17:30-17:50 PDL-1 vs TMB: do we have a winner? Fernando López-Ríos 17:50-18:10 Clinical applications of liquid biopsy: screening, molecular residual disease and new designs of clinical trials Rafael López López Joint session with Pharma Sponsor 18:10-18:25 TBD 18:25-18:40 Tumor DNA Digital NGS in Lunch Cancer; Guardant 360 Noemí Reguart 19:00 20:30 Guided Tour (optional) 20:30 Dinner at EL VIVERO Paseo Balmins, s/n

6 Monday 8 th October 2018 Time slot Topic / Title of presentation Chair Breakfast for young investigators TR protocols and projects: SPECTA: Screening Patients with thoracic tumors for Efficient Clinical Trial Access B. Besse Biobank and future TR projects S. Lantuejoul New proposals: BioRADON - L.Mezquita S. Lantejoul, S. Novello, F. Fachinetti 10:00 10:30 Young Investigators Projects II L. Hendriks, A. Levy Protocols in mesothelioma 1205: EORTC randomized phase II study of pleurectomy/ decortication (P/D) preceded or followed by chemotherapy in patients with early stage malignant pleural mesothelioma A-S Govaerts 10:30-11: (NEMO): Nintedanib as maintenance treatment of malignant pleural mesothelioma: a double-blind randomized phase II study of the EORTC Lung Cancer Group - S. Popat Concepts: 1752 (MESAVEL): Phase II trial in pretreated Malignant pleural MESothelioma with AVELumab in combination with Nintedanib or Chemotherapy - N. Reguart, F. Fachinetti T. Berghmans, G. Pasello 11:00-11:30 Coffee break 11:30 12:30 New proposals Wrap-up & Conclusions B. Besse End of the meeting B. Besse Lunch B. Besse, A-M. Dingemans, S. Novello

7 SPONSORS PLATINUM GOLD SILVER COLLABORATORS

8 FALL MEETING Sitges, 7th and 8th October, 2018

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