THE CRITICAL ROLE OF NURSES. Helping patients take control of their LDL-C to lower the risk of MI and stroke.

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1 THE CRITICAL ROLE OF NURSES Helping patients take control of their LDL-C to lower the risk of MI and stroke.

2 WHEN IT COMES TO REDUCING PATIENTS HIGH CHOLESTEROL, NURSES PLAY A KEY ROLE Many patients may suffer a myocardial infarction (MI) or stroke because of high, low-density lipoprotein cholesterol (LDL-C). 1,5 A subsequent MI or stroke is a real risk. 2 To help patients reduce their risk you have an important role: to educate MI and stroke patients about lowering their LDL-C. Your patients trust you. You spend a lot of time with patients and know who is at high risk of a MI or stroke. By educating your patients on the danger of high LDL-C, you play an important role in helping to relieve worry. Empower your patients Provide information to your patients on how to manage uncontrolled LDL-C. Know that you are empowering your patients to achieve better health.

3 HELPING YOUR PATIENTS UNDERSTAND THE RISK Globally over Reducing LDL-C is particularly critical in patients who have had multiple events or a recent cardiovascular event million people suffer from a MI or stroke every year. 3 1 in 20 PATIENTS WHO HAVE A MI MAY DIE 3 NEARLY 1 IN 3 WILL HAVE A SUBSEQUENT CARDIOVASCULAR EVENT. 2

4 YOU CAN MAKE A DIFFERENCE! Encourage your patients to: Make important lifestyle changes such as eating a healthy diet, quitting smoking and exercising more. Stay on therapy and remember to take the medication prescribed by the doctor to reduce the risk of another MI or stroke. Encourage patients to recognise and reduce their personal risk. High LDL-C is one of the most important and impactful modifiable risk factors. 4 If you sense your patient is concerned, it could be the perfect time to start a conversation about their cholesterol management and ensure they are aware of all their options.

5 RISK FACTORS INCLUDE: 4 LDL High LDL-C HDL Diabetes Hypertension Low HDL Inadequate fruit/vegetable intake Lack of exercise Obesity Consumption of alcohol Smoking Psychosocial factors

6 HELPING YOUR PATIENTS SIDE-BY-SIDE WITH THE DOCTOR Your patients are relying on you to help address their risk factors and chance of having a MI or stroke. If a patient s LDL-C is still too high after a MI or stroke, flag the test results to the doctor and work together to ensure your patients are on optimal treatment. CONSIDER INNOVATIVE THERAPIES FOR REDUCING LDL-C For some high-risk patients, statins and other traditional lipid-lowering therapies are not enough to lower high LDL-C. 6 Innovative therapies are an option for high-risk patients with uncontrolled LDL-C. 6,7

7 YOU MAKE A DIFFERENCE IN REDUCING RISK, HELPING RELIEVE WORRY AND AVOIDING AN EMERGENCY Make a difference today: Support your patients in reducing modifiable risk factors, including high LDL-C, for MI or stroke. 4 Identify patients for whom statins and other traditional lipidlowering therapies are not enough to lower their high LDL-C. Provide advice and resources to your patient to help them reduce their risk of a future MI or stroke. Partner with your patient and his or her health care team to ensure the best health outcome.

8 Visit for more information Referencias: 1. World Health Organization. Global Health Observatory (GHO) data; Raised Cholesterol. Available at: risk_factors/cholesterol_text/en/. Last accessed June Bhatt DL, Eagle KA, Ohman EM, et al. Comparative determinants of 4-year cardiovascular event rates in stable outpatientsat risk of or with atherothrombosis. JAMA.2010;304: Available at: Last accessed June World Health Organization. The PREMISE programme: country projects. Available at: priorities/secondary_prevention/country/en/index1.html. Last accessed June Yusuf S, Hawken S, Ôunpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet. 2004;364: Goldstein, J. L., & Brown, M. S. (2009). History of Discovery: The LDL Receptor. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(4), Fox K, Kostev K, Vultee C, et al. Lack of low-density lipoprotein cholesterol (LDL-C) goal attainment among high-risk patients using high or moderate intensity statin therapy in Germany. Eur Heart J /eurheartj/ehx502.P Sabatine et al. Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels - A Meta-analysis; JAMA Cardiol. doi: /jamacardio Amgen Middle East FZ-LLC Business Central Tower A, 2007 P.O Box , Dubai, UAE PR-NA-ARE Sep 18

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