References. 1. Personen E, Liuba P. Footprints of atherosclerotic coronary heart disease in children. Rev Port Cardiol 2004;23:
|
|
- Eileen Rodgers
- 6 years ago
- Views:
Transcription
1 IS FAMILY HISTORY OF PREMATURE CARDIOVASCULAR DISEASES APPROPRIATE FOR DETECTION OF DYSLIPIDEMIC CHILDREN IN POPULATION-BASED PREVENTIVE MEDICINE PROGRAMS? Roya Kelishadi, M.D., Associate Professor and Head, Preventive Pediatric Cardiology Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran, s: ; According to multiple studies, the early stages of atherosclerosis begin in early life, and the extent of its lesions correlates positively with plasma low density lipoprotein cholesterol (LDL- C) levels and negatively with plasma high density lipoprotein cholesterol (HDL-C) levels, even in childhood and young adulthood [1]. Cardiovascular diseases (CVDs) are caused by interaction of genetic and environmental factors. Genetic component is believed to be more predominant when atherosclerosis presents in young age; in addition, premature CVDs tend to run in families. Many studies have demonstrated the association of family history with unfavorable serum lipid levels [2]. The current scientific guidelines of The American Academy of Pediatrics [3], the American Heart Association [4], and the National Cholesterol Education Program [5] emphasize the screening of those children with a positive family history of premature CVD. They define CVD as premature when it occurs in relatives, including parents, grandparents, uncles and/or aunts before the age of 55 years; and the current algorithms for screening and follow up of such children are based on their serum total and LDL-cholesterol levels. Nevertheless, controversy exists as to the effectiveness of these guidelines; it remains unclear whether they are appropriate for various ethnic groups having different genetic background and diversity in lifestyle. Consequently for the first time in Iran, and to the best of our knowledge in Asia, we performed the current population-based survey entitled Childhood & Adolescence Surveillance and PreventIon of Adult Non-communicable disease: CASPIAN study [6] to compare the serum lipid profile of a large national representative sample of children and adolescents, aged 6-18 years, with reference values, and to evaluate the usefulness of the existing guidelines to screen children and adolescents for dyslipidemia. As presented in Figure 1, we found that in both genders and in all age groups, the mean serum triglycerides (TG) and its percentiles were significantly higher, and the mean and percentiles of total, low-density, and high density cholesterol (TC, LDL-C, and HDL-C) were significantly lower than the Lipid Research Clinic (LRC) values [7]. In total, 45.7% of participants had dyslipidemia; the most frequent ones were low HDL-C (24.8%) and hypertriglyceridemia (24.5%), followed by hypercholesterolemia (6.4%), and high LDL-C (6.3%), respectively. The mean serum lipid levels and the anthropometric measures were not significantly different among those with or without positive FH. The sensitivity, specificity, and
2 positive and negative predictive values for family history in detecting those children with dyslipidemia were 28.4%, 70.3%, 44.7%, and 53.8%, respectively. The low sensitivity of positive family history is suggested as the main disadvantage of the current guidelines for screening lipid disorders among youths [8]. In our study, this sensitivity was 28.4%, which was nearly similar to that reported from Canada (33.1%) [9], but higher than the study in U.S. (21.6%) [10]. Consistent with some other population-based studies [11], we did not find any significant difference in the lipid profile of children with and without a self-reported family history of premature CVD. Whereas in many previous studies including ours, in which CVD risk factors have been more prevalent in children of patients hospitalized for premature CVD [12-15], we suggest that this controversy among population-based studies and the medical researches conducted in offspring of hospitalized patients, is mainly due to the inaccuracy of self-reports of family history. Although in general, the validity of such data is shown to be fairly good [16], but some other studies suggest that such self-reports are inaccurate [9,17]. Our finding about the high prevalence of high TG and low HDL-C among the children of our community might be of interest. In Western countries, the prevalence of high total and LDLcholesterol is reported to be considerably higher than in our study. In a recent study, rural children in the U.S. had high total and LDL-cholesterol levels (26% and 20%, respectively) [18]. In Brazil, this prevalence is reported to be 27.9% and 26.4%, respectively [19]. In our study, the prevalence of hypertriglyceridemia and low HDL-C, i.e. the components of the metabolic syndrome were higher than that reported from Western countries. In our population, the mean and the percentiles for TG were higher, and that of HDL-C were lower than in Western countries. The prevalence of the metabolic syndrome is high among Iranian youths [20], which confirms the supposed ethnic predisposition to this type of dyslipidemia among Asians [21]. In addition, a genetic-environment interaction might explain such difference between communities, and necessitate further studies. Diets high in trans-unsaturated fat may lower HDL-C, increase TG levels, and interfere with fatty acid metabolism; our previous study indicated that the improper quality of the consumed fat that is rich in saturated and trans-fatty acids correlated with the high prevalence of dyslipidemia in Iranian youths [22]. The current guidelines for screening dyslipidemia among youths are based on the total and LDL cholesterol levels; we suggest that the high varieties in the type of lipid disorders in different communities should be considered as well. In countries where the prevalence of hypertriglyceridemia and low HDL-C is reported to be high in the adult population, screening of these lipids might be of greater importance than that of total and LDL cholesterol recommended by Western countries. In conclusion, considering that in our study, self-reported family history had low sensitivity, as well as low positive and negative predictive value in identifying dyslipidemic children and adolescents, we suggest that family history has more value in medical research than in population-based studies. The common lipid disorder in our community was hypertriglyceridemia and low HDL-C, i.e. the metabolic syndrome components, but not hypercholesterolemia that is prevalent in Western countries; therefore, we suggest that the current guidelines for screening lipid disorders in youths should consider such ethnic differences. References 1. Personen E, Liuba P. Footprints of atherosclerotic coronary heart disease in children. Rev Port Cardiol 2004;23:
3 2. Greenlund KJ, Valdez R, Bao WH, Wattigney WA, Srinivasan SR, Berenson GS. Verification of parental history of coronary artery disease and associations with adult offspring risk factors in a community sample: The Bogalusa Heart Study. Am J Med Sci 1997;313: American Academy of Pediatrics, Committee on Nutrition. Cholesterol in childhood. Pediatrics 1998;101: Kavey RW, Daniels SR, Ronald M, et al. American Heart Association guidelines for primary prevention of atherosclerotic cardiovascular disease beginning in childhood. Circulation 2003;107: National Cholesterol Education Program (NECP) Expert Panel (ATPIII). Executive summary of the third report of the National Cholesterol Education Program (NECP) expert panel on detection, evaluation and treatment of high blood cholesterol in adults. (Adult Treatment Panel III). JAMA 2001;285: Kelishadi R, Ardalan G, Gheiratmand R, Ramezani A. Is family history of premature cardiovascular diseases appropriate for detection of dyslipidemic children in population-based preventive medicine programs? CASPIAN Study. Pediatr Cardiol 2006;27(6): Tershakovec AM, Rader J. Disorders of lipoprotein metabolism and transport. In: Behrman RE, Kliegman RM, Jenson HB, editors. Nelson textbook of pediatrics. 17 th ed. W.B. Saunders: Philadelphia, 2004: Pankow JS, Folsom AR, Province MA, et al. Family history of coronary heart disease and hemostatic variables in middle-aged adults. Thromb Haemost 1997;77: O Loughlin J, Lauzon B, Paradis G, et al. Usefulness of the American Academy of Pediatrics Recommendations for identifying youths with hypercholesterolemia. Pediatrics 2004;113: Muratova VN, Islam SS, Demerath EW, Minor VE, Neal WA. Cholesterol screening among children and their parents. Prev Med 2001;33: Bailleul S, Couderc R, Rossignol C, et al. Lipoprotein(a) in childhood: relation with other atherosclerosis risk factors and family history of atherosclerosis. Clin Chem 1995;41: Kelishadi R, Sarraf Zadegan N, Nadery GA, Asgary S, Bashardoust N. Atherosclerosis risk factors in children and adolescents with or without family history of premature coronary artery disease. Med Sci Monit 2002;8: Kelishadi R, Naderi Gh, Asgary S. Oxidized LDL metabolites in children with high family risk for premature CVD. Indian J Pediatr 2002;69: Kelishadi R, Sabet B, Khosravi A. Anticardiolipin antibody of adolescents and age of myocardial infraction in parents. Med Sci Monit 2003;9: Makedou A, Kourti M, Makedou K, Lazaridou S, Varlamis G. Lipid profile of children with a family history of coronary heart disease or hyperlipidemia: 9-year experience of an outpatient clinic for the prevention of cardiovascular diseases. Angiology 2005;56: Kee F, Tiret L, Robo JY, et al. Reliability of reported family history of myocardial infarction. Br Med J 1993;307: Martin LM, Leff M, Calonge N, Garrett C, Nelson DE. Validation of self-reported chronic conditions and health services in a managed care population. Am J Prev Med 2000;18: Davis CL, Flickinger B, Moore D, Bassali R, Domel Baxter S, Yin Z. Prevalence of cardiovascular risk factors in school children in a rural Georgia community. Am J Med Sci 2005;330: Prieto Albino L, Arroyo Diez J, Vadillo Machota JM, Mateos Montero C, Galan Rebollo A. Prevalence of hyperlipidemia in children and adolescents in the Province of Caceres. Rev Esp Salud Publica 1998;72: Kelishadi R, Ardalan G, Gheiratmand R, Adeli K, Delavari A, Majdzadeh R, For TheCaspian Study Group. Paediatric metabolic syndrome and associated anthropometric indices: The CASPIAN Study. Acta Paediatr 2006;95(12):
4 21. Yusuf S, Reddy S, Ounpuu S, Anand S. Global burden of cardiovascular diseases. Part II. Variations in cardiovascular disease by specific ethnic groups and geographic regions and prevention strategies. Circulation 2001;104: Kelishadi R, Pour MH, Zadegan NS, et al. Fat intake and serum lipid profile in Iranian adolescents. Prev Med 2004; 39:760-6.
5 Figure1. Comparison of the mean serum lipids obtained in the current study versus the reference values [7]: CASPIAN Study Boys Girls
Comparison of Lipoprotein (a) and Apolipoproteins in Children with and without Familial History of Premature Coronary Artery Disease
Short Comunication Iran J Pediatr Jun 2008; Vol 18 ( No 2), Pp:159-162 Comparison of Lipoprotein (a) and Apolipoproteins in Children with and without Familial History of Premature Coronary Artery Disease
More informationPercentile of Serum Lipid Profile in Children at Eastern Iran
http:// ijp.mums.ac.ir Original Article Percentile of Serum Lipid Profile in Children at Eastern Iran Fatemeh Taheri 1, *Tayebeh Chahkandi 2, Toba Kazemi 3, Bita Bijari 4 1 Associate Professor of Pediatric,
More informationLipid Profiles and Prevalence of Dyslipidemia in Eastern Iranian Adolescents, Birjand, 2012
IJMS Vol 40, No 4, July 2015 Original Article Lipid Profiles and Prevalence of Dyslipidemia in Eastern Iranian Adolescents, Birjand, 2012 Fatemeh Taheri, MD; Tayebeh Chahkandi, MD; Toba Kazemi, MD; Bita
More information1389 (54 )1 - *** *** *** ** *** * * ** *** ( ) : /8/26 : 88/2/1 : (WC) (BMI) :.. (CVD) - : :
JQUMS, Vol.14, No.1, Spring 2010 18 Predicting risk factors of cardiovascular disease according to anthropometric measures in children and adolescents R Kelishadi* M Hashemipour** Z Faghihimani*** E Nazemi***
More informationComparison of Abnormal Cholesterol in Children, Adolescent & Adults in the United States, : Review
European Journal of Environment and Public Health, 2017, 1(1), 04 ISSN: 2468-1997 Comparison of Abnormal Cholesterol in Children, Adolescent & Adults in the United States, 2011-2014: Review Rasaki Aranmolate
More informationManagement of dyslipidaemia in HIV infected children: rationale for treatment algorithm
Management of dyslipidaemia in HIV infected children: rationale for treatment algorithm Authors: Julie Lanigan, Lisa Cooke and Clare Stradling Date of Preparation: September 2010 Date reviewed: October
More informationDisclosures. Pediatric Dyslipidemia Casey Elkins, DNP, NP C, CLS, FNLA. Learning Objectives. Atherogenesis. Acceptable Values
39 th National Conference on Pediatric Health Care Pediatric Dyslipidemia Casey Elkins, DNP, NP C, CLS, FNLA March 19-22, 2018 CHICAGO Disclosures Speakers Bureau Sanofi and Regeneron Learning Objectives
More informationCardiometabolics in Children or Lipidology for Kids. Stanley J Goldberg MD Diplomate: American Board of Clinical Lipidology Tucson, Az
Cardiometabolics in Children or Lipidology for Kids Stanley J Goldberg MD Diplomate: American Board of Clinical Lipidology Tucson, Az No disclosures for this Presentation Death Risk Approximately 40% of
More informationRelationship Between Blood Pressure and Lipid Profile on Obese Children
American Journal of Health Research 2015; 3(4): 198-202 Published online May 28, 2015 (http://www.sciencepublishinggroup.com/j/ajhr) doi: 10.11648/j.ajhr.20150304.11 ISSN: 2330-8788 (Print); ISSN: 2330-8796
More informationLearning Objectives. Cholesterol and Lipids in Kids: It s a Matter of the Heart. Is Atherosclerosis a Pediatric Disease?
Scott J. Soifer, MD Professor and Vice Chair Department of Pediatrics University of California, San Francisco UCSF Benioff Children s Hospital Cholesterol and Lipids in Kids: It s a Matter of the Heart
More informationThe investigation of serum lipids and prevalence of dyslipidemia in urban adult population of Warangal district, Andhra Pradesh, India
eissn: 09748369, www.biolmedonline.com The investigation of serum lipids and prevalence of dyslipidemia in urban adult population of Warangal district, Andhra Pradesh, India M Estari, AS Reddy, T Bikshapathi,
More informationAtherosclerotic cardiovascular disease remains the leading
AHA Scientific Statement American Heart Association Guidelines for Primary Prevention of Atherosclerotic Cardiovascular Disease Beginning in Childhood Rae-Ellen W. Kavey, MD; Stephen R. Daniels, MD, PhD;
More informationIs Universal Pediatric Lipid Screening Justified? YES. Damon Dixon, MD, FAAP Preventative Cardiology March 7 th, 2016
Is Universal Pediatric Lipid Screening Justified? YES Damon Dixon, MD, FAAP Preventative Cardiology March 7 th, 2016 None Disclosures What is a Pediatrician? Pediatrics is the specialty of medical science
More informationToward a Prudent Diet for Children
Committee on Nutrition Nutritional manipulation has been suggested as a mode of decreasing atherosclerosis. Atherosclerosis is a disease process that begins with fatty streaks during infancy and childhood
More informationManagement of dyslipidaemia in HIV infected children: rationale for treatment algorithm
Management of dyslipidaemia in HIV infected children: rationale for treatment algorithm Authors: Julie Lanigan, Lisa Cooke, Clare Stradling, Anton Tan Date of Preparation: September 2010 Date reviewed:
More informationLipid Profile in Uncomplicated Non-Diabetic Hypertensives
Lipid Profile in Uncomplicated Non-Diabetic Hypertensives Ali Akbar Tavasoli, MD; Masoumeh Sadeghi, MD; Masoud Pourmoghaddas, MD and Hamid Reza Roohafza, MD Abstract Background- Many risk factors have
More information1. Most of your blood cholesterol is produced by: a. your kidneys b. your liver c. your pancreas d. food consumption (Your liver)
I. TEST YOUR KNOWLEDGE OF CHOLESTEROL Choose the correct answer. 1. Most of your blood cholesterol is produced by: a. your kidneys b. your liver c. your pancreas d. food consumption (Your liver) 2. Only
More informationCorrespondence should be addressed to Roya Kelishadi;
International Endocrinology Volume 2013, Article ID 702095, 8 pages http://dx.doi.org/10.1155/2013/702095 Clinical Study Metabolic Syndrome and Cardiovascular Risk Factors in a National Sample of Adolescent
More informationLipid and Insulin Levels in Obese Children: Changes with Age and Puberty
Risk Factors and Chronic Disease Lipid and Insulin Levels in Obese Children: Changes with Age and Puberty Orit Pinhas-Hamiel,* Liat Lerner-Geva,* Nancy M. Copperman, and Marc S. Jacobson Abstract PINHAS-HAMIEL,
More information1/14/2013 Pediatric Cardiovascular Disease and the Future of our Children Linda Alwine FNP-BC Objectives Identify the prevalence and epidemiology of h
Pediatric Cardiovascular Disease and the Future of our Children Linda Alwine FNP-BC Objectives Identify the prevalence and epidemiology of hyperlipidemia. Identify risk factors that lead to the development
More information. Non HDL-c : Downloaded from ijdld.tums.ac.ir at 18:05 IRDT on Friday March 22nd Non HDL LDL. . LDL Non HDL-c
208-23 (2 ) 0 389 -. Non HDL * Downloaded from ijdld.tums.ac.ir at 8:05 IRDT on Friday March 22nd 209 Non HDL : LDL.. 5 3277 :.. odds ratio Chi-Square %3/9 Non HDL-C %2 LDL-C. %3 : Non-HDL-C LDL-C. (CI
More informationHereditary dyslipidaemias and combined risk factors in children with a family history of premature coronary artery disease
292 Department of Paediatrics, Malmö University Hospital, S-205 02 Malmö, Sweden T Sveger C-E Flodmark K Nordborg Department of Clinical Chemistry, Lund University Hospital, Lund, Sweden P Nilsson-Ehle
More information9/18/2017 DISCLOSURES. Consultant: RubiconMD. Research: Amgen, NHLBI OUTLINE OBJECTIVES. Review current CV risk assessment tools.
UW MEDICINE UW MEDICINE UCSF ASIAN TITLE HEALTH OR EVENT SYMPOSIUM 2017 DISCLOSURES Consultant: RubiconMD ESTIMATING CV RISK IN ASIAN AMERICANS AND PREVENTION OF CVD Research: Amgen, NHLBI EUGENE YANG,
More informationPOST GRADUATE DIPLOMA IN CLINICAL CARDIOLOGY (PGDCC) Term-End Examination June, 2015
No. of Printed Pages : 20 MCC-006 POST GRADUATE DIPLOMA IN CLINICAL 0 CARDIOLOGY (PGDCC) Term-End Examination June, 2015 MCC-006 : CARDIO VASCULAR EPIDEMIOLOGY Time : 2 hours Maximum Marks : 60 Note :
More informationFrequency of Dyslipidemia and IHD in IGT Patients
Frequency of Dyslipidemia and IHD in IGT Patients *Islam MS, 1 Hossain MZ, 2 Talukder SK, 3 Elahi MM, 4 Mondal RN 5 Impaired glucose tolerance (IGT) is often associated with macrovascular complications.
More informationPage 1. Disclosures. Background. No disclosures
Population-Based Lipid Screening in the Era of a Childhood Obesity Epidemic: The Importance of Non-HDL Cholesterol Assessment Brian W. McCrindle, Cedric Manlhiot, Don Gibson, Nita Chahal, Helen Wong, Karen
More informationThe New England Journal of Medicine ASSOCIATION BETWEEN MULTIPLE CARDIOVASCULAR RISK FACTORS AND ATHEROSCLEROSIS IN CHILDREN AND YOUNG ADULTS
ASSOCIATION BETWEEN MULTIPLE CARDIOVASCULAR RISK FACTORS AND ATHEROSCLEROSIS IN CHILDREN AND YOUNG ADULTS GERALD S. BERENSON, M.D., SATHANUR R. SRINIVASAN, PH.D., WEIHANG BAO, PH.D., WILLIAM P. NEWMAN
More informationEXECUTIVE SUMMARY OF THE MINOR RESEARCH PROJECT Submitted to UNIVERSITY GRANTS COMMISSION
1 A STUDY ON THE EFFECT OF DIET & LIFE STYLE ON THE INCIDENCE OF CORONARY ARTERY DISEASE IN MODERATELY DRINKING EX MILITARY MEN IN PATHANAMTHITTA DISTRICT. EXECUTIVE SUMMARY OF THE MINOR RESEARCH PROJECT
More informationSTATIN UTILIZATION MANAGEMENT CRITERIA
STATIN UTILIZATION MANAGEMENT CRITERIA DRUG CLASS: HMG Co-A Reductase Inhibitors & Combinations Agents which require prior review: Advicor (niacin extended-release/lovastatin) Crestor (rosuvastatin)(5mg,10mg,
More information2.5% of all deaths globally each year. 7th leading cause of death by % of people with diabetes live in low and middle income countries
Lipid Disorders in Diabetes (Diabetic Dyslipidemia) Khosrow Adeli PhD, FCACB, DABCC Head and Professor, Clinical Biochemistry, The Hospital for Sick Children, University it of Toronto Diabetes A Global
More informationManagement of Lipid Disorders in Children and Adolescents
Management of Lipid Disorders in Children and Adolescents Britni Delva, MPAS, PA-C, CLS Disclosures Disclosures Consultant/speaker Research funding Stock ownership/corporate boards-employment Off label
More informationCurrent Cholesterol Guidelines and Treatment of Residual Risk COPYRIGHT. J. Peter Oettgen, MD
Current Cholesterol Guidelines and Treatment of Residual Risk J. Peter Oettgen, MD Associate Professor of Medicine Harvard Medical School Director, Preventive Cardiology Beth Israel Deaconess Medical Center
More informationMetabolic Syndrome: Why Should We Look For It?
021-CardioCase 29/05/06 15:04 Page 21 Metabolic Syndrome: Why Should We Look For It? Dafna Rippel, MD, MHA and Andrew Ignaszewski, MD, FRCPC CardioCase presentation Andy s fatigue Andy, 47, comes to you
More informationStatistical Fact Sheet Populations
Statistical Fact Sheet Populations At-a-Glance Summary Tables Men and Cardiovascular Diseases Mexican- American Males Diseases and Risk Factors Total Population Total Males White Males Black Males Total
More informationNEW GUIDELINES FOR CHOLESTEROL
NEW GUIDELINES FOR CHOLESTEROL NEW CHOLESTEROL GUIDELINES 2013 Recently updated guidelines for the treatment of high blood cholesterol levels is a major update since 2002. The news media have trumpeted
More informationTHE CORRELATION BETWEEN LIPID PROFILE AND STRESS LEVELS IN CENTRAL IRAN: ISFAHAN HEALTHY HEART PROGRAM
THE CORRELATION BETWEEN LIPID PROFILE AND STRESS LEVELS IN CENTRAL IRAN: ISFAHAN HEALTHY HEART PROGRAM Maryam Shahnam (), Hamidreza Roohafza (2), Masoumeh Sadeghi (3), Ahmad Bahonar (4), Nizal Sarrafzadegan
More informationStudy of serum Lipid Profile patterns of Indian population in young Ischaemic Heart Disease
Original article: Study of serum Lipid Profile patterns of Indian population in young Ischaemic Heart Disease Dr Sonu Yadav, Dr Abhijit Nikam, Dr Vivek Chiddarwar, Dr A L Kakrani Department of Medicine,
More informationHyperlipidemia. Prepared by : Muhannad Mohammed Supervisor professor : Dr. Ahmed Yahya Dallalbashi
Hyperlipidemia Prepared by : Muhannad Mohammed Supervisor professor : Dr. Ahmed Yahya Dallalbashi Outline The story of lipids Definition of hyperlipidemia Classification of hyperlipidemia Causes of hyperlipidemia
More informationDIET, HYPERTENSION, HYPERCHOLESTEROLEMIA AND DIABETES IN ISCHEMIC HEART DISEASES
Original Article DIET, HYPERTENSION, HYPERCHOLESTEROLEMIA AND DIABETES IN ISCHEMIC HEART DISEASES Salimzadeh Hamideh 1, Mohsenpour Behzad 2, Ghaderi Ebrahim 3, Eftekhar Hassan 4, Salarifar Mojtaba 5 ABSTRACT
More informationIndex. cardiology.theclinics.com. Note: Page numbers of article titles are in boldface type.
Index Note: Page numbers of article titles are in boldface type. A ACC/AHA. See American College of Cardiology/ ACE inhibitors. See Angiotensin-converting enzyme (ACE) inhibitors American College of Cardiology/American
More informationEstablished Risk Factors for Coronary Heart Disease (CHD)
Getting Patients to Make Small Lifestyle Changes That Result in SIGNIFICANT Improvements in Health - Prevention of Diabetes and Obesity for Better Health Maureen E. Mays, MD, MS, FACC Director ~ Portland
More informationARE YOU AT RISK OF A HEART ATTACK OR STROKE? Understand How Controlling Your Cholesterol Reduces Your Risk
ARE YOU AT RISK OF A HEART ATTACK OR STROKE? Understand How Controlling Your Cholesterol Reduces Your Risk CONSIDER YOUR HEART HEALTH: REDUCE YOUR CHOLESTEROL Uncontrolled or continuous high cholesterol
More informationDiabetic Dyslipidemia
Diabetic Dyslipidemia Dr R V S N Sarma, M.D., (Internal Medicine), M.Sc., (Canada), Consultant Physician Cardiovascular disease (CVD) is a significant cause of illness, disability, and death among individuals
More informationChildhood Overweight, Obesity, and the Metabolic Syndrome in Developing Countries
Epidemiologic Reviews Advance Access published May 3, 2007 Epidemiologic Reviews Copyright ª 2007 by the Johns Hopkins Bloomberg School of Public Health All rights reserved; printed in U.S.A. DOI: 10.1093/epirev/mxm003
More informationRole of diet in prevention and treatment of hypercholesterolaemia/hypertriglyceridaemia in children C. Hartman (IL)
ESPEN Congress Geneva 2014 NUTRITION IN PAEDIATRIC PATIENTS 2 Role of diet in prevention and treatment of hypercholesterolaemia/hypertriglyceridaemia in children C. Hartman (IL) Nutritional Treatment of
More informationLatest Guidelines for Lipid Management
Latest Guidelines for Lipid Management Goals Recognize the differences between different guidelines Understand the effective strategies to tailor lipid lowering therapies based on evidence and guideline
More informationRisk Factors and Primary and Secondary Prevention of Coronary Heart Disease
Special Issue Risk Factors and Primary and Secondary Prevention of Coronary Heart Disease Shung Chull Chae, M.D. Department of Internal Medicine / Division of Cardiology Kyungpook National University College
More informationPlasma fibrinogen level, BMI and lipid profile in type 2 diabetes mellitus with hypertension
World Journal of Pharmaceutical Sciences ISSN (Print): 2321-3310; ISSN (Online): 2321-3086 Published by Atom and Cell Publishers All Rights Reserved Available online at: http://www.wjpsonline.org/ Original
More informationDiabetes and Heart Disease. Sarah Alexander, MD, FACC Assistant Professor of Medicine Rush University Medical Center
Diabetes and Heart Disease Sarah Alexander, MD, FACC Assistant Professor of Medicine Rush University Medical Center No conflicts of interest or financial relationships to disclose. 2 What s the problem??
More informationARTICLE. Childhood Passive Smoking, Race, and Coronary Artery Disease Risk. William B. Moskowitz, MD; Pamela F. Schwartz, PhD; Richard M.
Childhood Passive Smoking, Race, and Coronary Artery Disease Risk The MCV Twin Study ARTICLE William B. Moskowitz, MD; Pamela F. Schwartz, PhD; Richard M. Schieken, MD Background: Children with long-term
More informationPrevalence of Overweight and Obesity among Iranian School Children in Different Ethnicities
Original Article Iran J Pediatr Dec 2011; Vol 21 (No 4), Pp: 514-520 Prevalence of Overweight and Obesity among Iranian School Children in Different Ethnicities Seyed-Jalil Mirmohammadi 1, MD; Rahmatollah
More informationClinical Recommendations: Patients with Periodontitis
The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: Periodontitis and Atherosclerotic Cardiovascular Disease. Friedewald VE, Kornman KS, Beck JD, et al. J Periodontol 2009;
More informationTHE EFFECT OF VITAMIN-C THERAPY ON HYPERGLYCEMIA, HYPERLIPIDEMIA AND NON HIGH DENSITY LIPOPROTEIN LEVEL IN TYPE 2 DIABETES
Int. J. LifeSc. Bt & Pharm. Res. 2013 Varikasuvu Seshadri Reddy et al., 2013 Review Article ISSN 2250-3137 www.ijlbpr.com Vol. 2, No. 1, January 2013 2013 IJLBPR. All Rights Reserved THE EFFECT OF VITAMIN-C
More informationPrevalence and trends of obesity in Indian school children of different socioeconomic class.
Prevalence and trends of obesity in Indian school children of different socioeconomic class. Dr. Nazeem I. Siddiqui Dr. Mrs. S. Bose SAIMS, Medical College & P.G. Institute, Indore-Ujjain state highway,
More informationCARING FOR A LOVED ONE AFTER A HEART ATTACK OR STROKE
CARING FOR A LOVED ONE AFTER A HEART ATTACK OR STROKE AFTER YOUR LOVED ONE HAS HAD A HEART ATTACK OR STROKE Heart attack and stroke affects the whole family. If your loved one has had a heart attack or
More informationHypertension with Comorbidities Treatment of Metabolic Risk Factors in Children and Adolescents
Hypertension with Comorbidities Treatment of Metabolic Risk Factors in Children and Adolescents Stella Stabouli Ass. Professor Pediatrics 1 st Department of Pediatrics Hippocratio Hospital Evaluation of
More informationPlant sterols/stanols for cholesterol lowering and prevention of cardiovascular disease
Plant sterols/stanols for cholesterol lowering and prevention of cardiovascular disease Prof Dr Elke A. Trautwein, Senior Scientist Cardiovascular Health, Unilever, on behalf of the International Plant
More informationComprehensive Treatment for Dyslipidemias. Eric L. Pacini, MD Oregon Cardiology 2012 Cardiovascular Symposium
Comprehensive Treatment for Dyslipidemias Eric L. Pacini, MD Oregon Cardiology 2012 Cardiovascular Symposium Primary Prevention 41 y/o healthy male No Medications Normal BP, Glucose and BMI Social History:
More informationConflict of Interest Disclosure. Learning Objectives. Learning Objectives. Guidelines. Update on Lifestyle Guidelines
Conflict of Interest Disclosure Updates for the Ambulatory Care Pharmacist: Dyslipidemia and CV Risk Assessment No conflicts of interest to disclose 2014 Updates to the Updates in Ambulatory Care Pharmacy
More informationImpact of Chronicity on Lipid Profile of Type 2 Diabetics
Impact of Chronicity on Lipid Profile of Type 2 Diabetics Singh 1, Gurdeep & Kumar 2, Ashok 1 Ph.D. Research Scholar, Department of Sports Science, Punjabi University Patiala, India, Email: drgurdeep_sahni@yahoo.co.in
More informationFamilial hypercholesterolaemia in children and adolescents
Familial hypercholesterolaemia in children and adolescents Rationale and recommendations for early identification and treatment European Atherosclerosis Society Consensus Panel Slide deck adapted from:
More informationGoing Coconut over Saturated Fat? Why So Much Confusion? Part 1 Interpreting Conflicting Research
Going Coconut over Saturated Fat? Why So Much Confusion? Part 1 Interpreting Conflicting Research Disclosures Alice H Lichtenstein Board Member/Advisory Panel Food and Nutrition Board, National Academies
More informationObservations on US CVD Prevention Guidelines. Donald M. Lloyd-Jones, MD ScM FACC FAHA
Observations on US CVD Prevention Guidelines Donald M. Lloyd-Jones, MD ScM FACC FAHA What are Guidelines? Evidence Base for Guidelines Tricoci, JAMA 2009 Evidence Base for Guidelines Tricoci, JAMA 2009
More informationB. Patient has not reached the percentage reduction goal with statin therapy
Managing Cardiovascular Risk: The Importance of Lowering LDL Cholesterol and Reaching Treatment Goals for LDL Cholesterol The Role of the Pharmacist Learning Objectives 1. Review the role of lipid levels
More informationREAGENTS. RANDOX sdldl CHOLESTEROL (sdldl-c) SIZE MATTERS: THE TRUE WEIGHT OF RISK IN LIPID PROFILING
REAGENTS RANDOX sdldl CHOLESTEROL (sdldl-c) SIZE MATTERS: THE TRUE WEIGHT OF RISK IN LIPID PROFILING Randox sdldl Cholesterol (sdldl-c) Size Matters: The True Wight of Risk in Lipid Profiling 1. BACKGROUND
More informationPattern of plasma lipoprotein (a) in Sudanese patients with coronary
Pattern of plasma lipoprotein (a) in Sudanese patients with coronary artery disease Mansour Eltahir Farah 1, Khairia Eltahir Abdullah 2, Huda HM Elhassan 3, Mohammed O EH Gadour 1, Mohammed Saeed Alkhaleefa
More informationDiabetes Mellitus: A Cardiovascular Disease
Diabetes Mellitus: A Cardiovascular Disease Nestoras Mathioudakis, M.D. Assistant Professor of Medicine Division of Endocrinology, Diabetes, & Metabolism September 30, 2013 1 The ABCs of cardiovascular
More informationPediatric Dyslipidemia: Angela Gooden MSN, RN, CPNP- AC/PC, Texas Children s Hospital, Pediatric Cardiology
Pediatric Dyslipidemia: Angela Gooden MSN, RN, CPNPAC/PC, Texas Children s Hospital, Pediatric Cardiology Objectives Define pediatric dyslipidemia Describe the association between pediatric dyslipidemia
More informationResearch Article Gender Differences Time Trends for Metabolic Syndrome and Its Components among Tehranian Children and Adolescents
Cholesterol Volume 2012, Article ID 804643, 6 pages doi:10.1155/2012/804643 Research Article Gender Differences Time Trends for Metabolic Syndrome and Its Components among Tehranian Children and Adolescents
More informationIndian Journal of Basic & Applied Medical Research; December 2011: Issue-1, Vol.-1, P
Comprehensive levels of Serum Enzymes and Lipid Profile testing in MI and Stable Angina Subjects. K.Satya Narayana*, Dr.Anija Uchuru**, Dr.Ivvala Anand Shaker*, S.Saleem Basha*, K.Suresh Babu* *Dept of
More informationTo Screen or Not to Screen and Other Assorted Cholesterol Questions
To Screen or Not to Screen and Other Assorted Cholesterol Questions Sarah D. de Ferranti, MD MPH Department of Cardiology Children s Hospital, Boston 6/5/10 UCSF sarah.deferranti@cardio.chboston.org Topics
More informationPEDIATRIC obesity is a complex and growing
Research Papers Metabolic Syndrome in Childhood Obesity Semiz Serap*, Bican Mevlüt*, Çakaloz Inanç and Semiz Ender From the Departments of Pediatric Endocrinology, Pediatrics, and Cardiology, Pamukkale
More informationGUIDELINES FOR DYSLIPIDEMIA MANAGEMENT AND EDUCATION THROUGH NOVA SCOTIA DIABETES CENTRES
GUIDELINES FOR DYSLIPIDEMIA MANAGEMENT AND EDUCATION THROUGH NOVA SCOTIA DIABETES CENTRES Prepared by DCPNS Action Committee Dr. Lynne Harrigan Brenda Cook Peggy Dunbar Bev Harpell with the assistance
More informationCardiovascular risk factors in school children from low middle income families in Karachi, Pakistan
ecommons@aku Section of Haematology/Oncology Department of Medicine January 1994 Cardiovascular risk factors in school children from low middle income families in Karachi, Pakistan Salma H. Badruddin Aga
More informationLipid Profile Analysis of Patients in a Saudi University Clinic
Public Health International 2017; 2(3): 89-95 http://www.sciencepublishinggroup.com/j/phi doi: 10.11648/j.phi.20170203.11 Lipid Analysis of Patients in a Saudi University Clinic Yasser Taher Al-Hassan
More informationMarshall Tulloch-Reid, MD, MPhil, DSc, FACE Epidemiology Research Unit Tropical Medicine Research Institute The University of the West Indies, Mona,
Marshall Tulloch-Reid, MD, MPhil, DSc, FACE Epidemiology Research Unit Tropical Medicine Research Institute The University of the West Indies, Mona, Jamaica At the end of this presentation the participant
More informationFebruary 10, Division of Dockets Management HFA-305 Food and Drug Administration 5630 Fishers Lane, Room 1061 Rockville, MD 20852
February 10, 2014 Division of Dockets Management HFA-305 Food and Drug Administration 5630 Fishers Lane, Room 1061 Rockville, MD 20852 Re: Docket No. FDA-2013-N-1317 Dear Sir or Madam: The American Heart
More informationManagement of Post-transplant hyperlipidemia
Management of Post-transplant hyperlipidemia B. Gisella Carranza Leon, MD Assistant Professor of Medicine Lipid Clinic - Vanderbilt Heart and Vascular Institute Division of Diabetes, Endocrinology and
More informationPalm Oil: A Preferred Healthy Dietary Choice
Palm Oil: A Preferred Healthy Dietary Choice Kalyana Sundram, PhD Deputy Chief Executive Officer & Director, Science & Environment Malaysian Palm Oil Council (MPOC) Palm Kernel Oil (Oleochemical Applications
More informationA comparative study on the fasting and post prandial lipid levels as a cardiovascular risk factor in patients with type 2 diabetes mellitus
Original Research Article A comparative study on the fasting and post prandial lipid levels as a cardiovascular risk factor in patients with type 2 diabetes mellitus Deepa Kalikavil Puthenveedu 1, Sundaraj
More informationOriginal Article J Clin Med Res. 2016;8(6): ress. Elmer
Elmer ress Original Article J Clin Med Res. 2016;8(6):431-436 Associations of Apolipoprotein A, High-Sensitivity C-Reactive Protein and Fasting Plasma Insulin in Obese Children With and Without Family
More informationDr Diwanshu Sharma* Dr Shafiqa Aslam** Dr Rani Walia***Dr P D Gupta****
A COMPARATIVE STUDY TO MEASURE EFFECTIVE REDUCTION IN LDL CHOLESTEROL USING ROSUVASTATIN 10 mg & ATORVASTATIN 20 mg THERAPY IN HYPERLIPIDEMIA PATIENTS IN HARYANA POPULATION Dr Diwanshu Sharma* Dr Shafiqa
More informationAssessing Cardiovascular Risk to Optimally Stratify Low- and Moderate- Risk Patients. Copyright. Not for Sale or Commercial Distribution
CLINICAL Viewpoint Assessing Cardiovascular Risk to Optimally Stratify Low- and Moderate- Risk Patients Copyright Not for Sale or Commercial Distribution By Ruth McPherson, MD, PhD, FRCPC Unauthorised
More informationNon-fasting Lipid Profile Getting to the Heart of the Matter! Medimail Dec 2017
Non-fasting Lipid Profile Getting to the Heart of the Matter! Medimail Dec 2017 Historical Basis for Fasting Lipids The initial classifications of hyperlipidemia proposed in 1967 were genetic and required
More informationZinc and Copper Status in Children with High Family Risk of Premature Cardiovascular Disease
Zinc and Copper Status in Children with High Family Risk of Premature Cardiovascular Disease Roya Kelishadi, MD; Hassan Alikhassy, MS; Masoud Amiri, MS From the Departments of Pediatrics, Nutrition and
More informationTitle for Paragraph Format Slide
Title for Paragraph Format Slide Presentation Title: Month Date, Year Atherosclerosis A Spectrum of Disease: February 12, 2015 Richard Cameron Padgett, MD Executive Medical Director, OHVI Pt RB Age 38
More informationISCHEMIC HEART DISEASE: Role of Total Cholesterol: HDL C Ratio as an Important Indicator Compared to LDL C.
International Journal of Biotechnology and Biochemistry ISSN 0973-2691 Volume 14, Number 1 (2018) pp. 13-17 Research India Publications http://www.ripublication.com ISCHEMIC HEART DISEASE: Role of Total
More informationEFFICIENCY AND COST-EFFECTIVENESS OF DYSLIPIDEMIA SCREENING METHODS AMONG WORKERS IN BANGKOK
EFFICIENCY AND COST-EFFECTIVENESS OF DYSLIPIDEMIA SCREENING METHODS AMONG WORKERS IN BANGKOK Unchalee Sanguantrakul, Wiroj Jiamjarasrangsi and Thosporn Vimolket 1 Department of Preventive and Social Medicine,
More informationThe new guidelines issued in PRESENTATIONS... Future Outlook: Changing Perspectives on Best Practice
... PRESENTATIONS... Future Outlook: Changing Perspectives on Best Practice Based on a presentation by Daniel J. Rader, MD Presentation Summary The guidelines recently released by the National Cholesterol
More informationLIPID CLUB Rome, 2014
LIPID CLUB Rome, 2014 June the 6h 6th Hyperlipidaemia in FH Children Ornella Guardamagna University of Torino DICLOSURES Medpace Kowa DSMB member MSD, Pfizer, Synageva Investigator in industry funded trials
More information4/14/2018 DYSLIPIDEMIA CASES. Mary Malloy, MD. I have nothing to disclose
DYSLIPIDEMIA CASES Mary Malloy, MD I have nothing to disclose 1 Case 1 A 24 year old healthy, slender woman is referred because she has a family history of premature CAD (mother, age 59, had onset of angina
More informationEffect of mixed diet on lipid fractions levels in Coronary Heart diseases in adults of western Maharashtra region of India.
Effect of mixed diet on lipid fractions levels in Coronary Heart diseases in adults of western Maharashtra region of India. nervous system frequency provokes transient cerebral Dr.Javed Bakas Mulla, Dept.
More informationDyslipidemia in the light of Current Guidelines - Do we change our Practice?
Dyslipidemia in the light of Current Guidelines - Do we change our Practice? Dato Dr. David Chew Soon Ping Senior Consultant Cardiologist Institut Jantung Negara Atherosclerotic Cardiovascular Disease
More informationRisk factors for atherosclerosis in children and adolescents with family history of premature coronary artery disease
0021-7557/04/80-02/135 Jornal de Pediatria Copyright 2004 by Sociedade Brasileira de Pediatria ORIGINAL ARTICLE Risk factors for atherosclerosis in children and adolescents with family history of premature
More informationAssociation between Plasma Homocysteine Concentrations and Carotid Intima-Media Thickness in Patients with Coronary Artery Disease
Association between Plasma Homocysteine Concentrations and Carotid Intima-Media Thickness in Patients with Coronary Artery Disease ROXANA BUZAŞ, CORINA ŞERBAN, IOANA SUCEAVA, DANIEL LIGHEZAN University
More informationBiomed Environ Sci, 2016; 29(3): LI Jian Hong, WANG Li Min, LI Yi Chong, ZHANG Mei, and WANG Lin Hong #
Biomed Environ Sci, 2016; 29(3): 205-211 205 Letter to the Editor Prevalence of Major Cardiovascular Risk Factors and Cardiovascular Disease in Women in China: Surveillance Efforts LI Jian Hong, WANG Li
More informationUpdate on Lipid Management in Cardiovascular Disease: How to Understand and Implement the New ACC/AHA Guidelines
Update on Lipid Management in Cardiovascular Disease: How to Understand and Implement the New ACC/AHA Guidelines Paul Mahoney, MD Sentara Cardiology Specialists Lipid Management in Cardiovascular Disease
More informationTreatment of severe Familial Hypercholesterolemia LDL Apheresis
Treatment of severe Familial Hypercholesterolemia LDL Apheresis Identifying and Treating Severe Familial Hypercholesterolemia October 14-15, 2017 Dubai, UAE Dr. Khalid Al-Waili, MD, FRCPC, DABCL Senior
More informationEFFECT OF LYCOPENE IN TOMATO SOUP AND TOMATO JUICE ON THE LIPID PROFILE OF HYPERLIPIDEMIC SUBJECTS
EFFECT OF LYCOPENE IN TOMATO SOUP AND TOMATO JUICE ON THE LIPID PROFILE OF HYPERLIPIDEMIC SUBJECTS Nora Vigasini, Assistant Professor, Department of Home Science, Women s Christian College, Chennai, noravigas@gmail.com
More informationAtherosclerotic Disease Risk Score
Atherosclerotic Disease Risk Score Kavita Sharma, MD, FACC Diplomate, American Board of Clinical Lipidology Director of Prevention, Cardiac Rehabilitation and the Lipid Management Clinics September 16,
More information