SYMPOSIUM ON INNOVATIVE CONCEPTS FOR TREATING NEURODEGENERATIVE DISEASES PROGRAMME September 2015

Transcription

1 Day 0 Tuesday 22/09: 17:00-20:00 High school and Students Activities Time SYMPOSIUM ON INNOVATIVE CONCEPTS FOR Topic 17:00 19:00 High school and students coaching on the different activities : Mind Map / Videos / Webbased timelines (Meeting place : MBC) Day1 Wednesday 23/09: 10:00-10:45 Press Conference restricted to Journalists and NEURINOX Members Time Topic 10:00 10:45 Karl-Heinz Krause, NEURINOX Project Director, altogether with the Partners of the NEURINOX Project will answer the journalists questions (Karl-Heinz Krause, Professor of Medicine, Faculty of Medicine & University Hospitals, Geneva, Switzerland) Day1 Wednesday 23/09: 10:00-12:30 10:00-10:40 Registration and welcome coffee 10:40-10:50 Welcome Address Adriano Chio, NEURINOX representative (Adriano Chio, Professor of Neurology, Director of ALS Center, Torino, Italy) 10:50-11:00 Introduction Karl-Heinz Krause, NEURINOX Project Director Karl-Heinz Krause, Professor of Medicine, Faculty of Medicine & University Hospitals, Geneva, Switzerland. KH Krause is also the Director of the NEURINOX Project) - 1 -

2 14:00-15:30 SYMPOSIUM ON INNOVATIVE CONCEPTS FOR Day1 Wednesday 23/09: 10:00-12:30 Epilepsy Session: Chairperson: Antoine Depaulis, NEURINOX representative, Joseph Fourier University, France 11:00-11:20 Epilepsy from a patient s perspective Catherine Dirand, representative of epileptic patients (Catherine Diran is a French singer, a book writer, Film Director. She is currently managing a film dealing with her own case as an epileptic person facing her day to day life) 11:20-11:30 Video introducing the pathology 11:30-11:50 Current treatment options Frank Tennigkeit, UCB Pharma, Germany of Epilepsy (Frank Tennigkeit, is part of the Asset Development Clinical Lead of the UCB Seizure Freedom Mission - the team within UCB Neurology that is dealing with epilepsy) 11:50-12:10 Microglia; the Defenders of the brain Brian A. MacVicar, Co-Director, Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia, Canada 12:10-12:30 Discussion Session Moderator, Antoine Depaulis, NEURINOX representative Discussion session with patient groups/students/scientists 12:30-14:00 Lunch break High school and students activities : Students coaching (13:00-14:00) Day 1 Wednesday 23/09: 14:00-15:30 ALS Session: Chairperson: Adriano Chio, NEURINOX representative, University of Torino, Italy 14:00-14:20 ALS from a patient s perspective Mario Melazzini, representative of ALS patients & Former President of ARISLA 14:20-14:30 Video introducing the pathology 14:30-14:50 Current treatment options of ALS Donald Johns, Vice President, Neurologist and Head of ALS ihub of BIOGEN, USA 14:50-15:10 ALS, Alzheimer, Parkinson: an inflammation of the brain? Karl-Heinz Krause, NEURINOX Project Director (Karl-Heinz Krause, Professor of Medicine, Faculty of Medicine & University Hospitals of Geneva, Switzerland. KH Krause is also the Director of the NEURINOX Project) 15:10-15:30 Discussion Session Moderator, Adriano Chio, NEURINOX representative Discussion session with patient groups/students/scientists - 2 -

3 16:00-17:30 15:30-16:00 Coffee break SYMPOSIUM ON INNOVATIVE CONCEPTS FOR Day 1 Wednesday 23/09: 16:00-17:30 MS Session: Chairperson : Tomas Olsson, NEURINOX representative, Karolinska Institut, Sweden 16:00-16:20 MS from a patient s perspective Louise Hoffsten, representative of MS patients (In 1996, Louise was diagnosed with multiple sclerosis, but despite the complications and occasional depressions - mirrored in the book/record Blues - she continues to write, tour and perform music) 16:20-16:30 Video introducing the pathology 16:30-16:50 Current treatment options of MS Fredrik Piehl, NEURINOX representative (Fredrik Piehl is a Research Team Leader at the Department of Clinical Neuroscience (CNS) of Karolinska Institut, Sweden) 16:50-17:10 Reactive oxygen based drugs as treatment for MS and other autoimmune diseases Peter Olofsson, NEURINOX representative (Peter Olofsson, CEO REDOXIS, Sweden) 17:10-17:30 Discussion Session Moderator, Tomas Olsson, NEURINOX representative Discussion session with patient groups/students/scientists and a moderator. 17:30 18:00 High school and students activities: students coaching 20:00 Social event Dinner in the City For all attendees, speakers and chairpersons - 3 -

4 SYMPOSIUM ON INNOVATIVE CONCEPTS FOR Day 2 Thursday 24/09: 08:45-18:20 Public event devoted to the scientific and industry communities 8:45-9:15 Registration and welcome coffee 9:15-9:30 Welcome Address Adriano Chio, NEURINOX representative (Adriano Chio, Professor of Neurology, Director of ALS Center, Torino, Italy) Pathophysiology Session: Chairperson: Vincent Jaquet, NEURINOX Project Scientific Coordinator, University of Geneva, Switzerland 09:30 10:00 Physiological and pharmacological regulation of NOX activity: An overview 10:00 10:30 Genetic control of NOX2 genes crucial for regulating inflammation Dave Lambeth,SAB member of NEURINOX Professor of Pathology, Emory University Medical School, Atlanta Rikard Holmdahl, NEURINOX representative (Rikard Holmdahl, Head of Division of Medical Inflammation Research at Karolinska Institut, Stockholm, Sweden) 10:30-11:00 "Neurodegeneration and neuroinflammation in ALS" Maria Teresa Carri, University of Rome "Tor Vergata", Italy (Maria Teresa Carri, Professor of Biochemistry, Department of Biology, University of Rome Tor Vergata) 11:00-11:45 Coffee break 11:45-12:15 The molecular basis of prion toxicity Adriano Aguzzi, NEURINOX representative 12:15-12:45 A role for NOX enzymes in epileptogenesis? Presentation of a set of data including data from transcriptomics, proteomics and tissue labeling in UJF model as well as a short presentation on the 'omics' data. (Adriano Aguzzi, Director, Institute of Neuropathology, University Hospital, Zürich, Switzerland) Antoine Depaulis, NEURINOX representative Antoine Depaulis, Neuroscientist in Epileptology, Grenoble, France) 12:45-14:00 Lunch buffet High school and students activities: students coaching (13:00-14:00) - 4 -

5 SYMPOSIUM ON INNOVATIVE CONCEPTS FOR Day 2 Thursday 24/09: 08:45 18:20 Public event devoted to the scientific and industry communities Biomarkers and Personalized Medicine: What do we know about the individual pathways => looking at genetics, ROS generation. Chairperson : Despina Sanoudou, NEURINOX representative, UOA, Greece 14:00 14:30 Overview of the personalized medicine of neurodegenerative disease 14:30 15:00 Presentation on oxidation products of arachidonic acid potential biomarkers for progressive multiple sclerosis. Isoprostanes in MS 15:00 15:30 Nox genes against severity measures of MS and against phagoburst Adriano Chio, NEURINOX representative (Adriano Chio, Professor of Neurology, Director of ALS Center, Torino, Italy) Roland Stocker, NEURINOX representative (Roland Stocker, Head, Vascular Biology Division, Victor Chang Cardiac Research Institute, Sydney, Australia) Ingrid Kockum, NEURINOX representative (Ingrid Kockum, Research Team Leader, Department of Clinical Neurosciences, Karolinska Institut, Sweden) 15:30 16:30 Coffee break and poster session New Therapy Development: Chairperson : Karl-Heinz Krause, NEURINOX Project Director, University of Geneva, Switzerland (10 minute introduction) 16:40 17:10 NOX2 pathway modulation in animal models of neuro autoimmune diseases Malin Hultqvist, NEURINOX representative (Malin Hultqvist, CSO Redoxis, Sweden) 17:10-17:40 GKT drug development Jeanette Wood, NEURINOX representative (Jeanette Wood, CSO, Genkyotex S.A, Switzerland) 17:40-18:10 Therapeutic strategies to ameliorate iron toxicity in Alzheimer's and Parkinson' Diseases Roberta J Ward, catholique université de Louvain, Louvain-la-Neuve-Belgium and Imperial College, London, UK 18:10-18:30 Conclusion of the day Vincent Jaquet, NEURINOX Project Scientific Coordinator (Vincent Jaquet, Lecturer, Department of Pathology & Immunology, Faculty of Medicine, University of Geneva. Vincent Jaquet is also the NEURINOX Project Scientific Coordinator) 18:30-20:00 High school and students activities: Project finalising - 5 -

6 SYMPOSIUM ON INNOVATIVE CONCEPTS FOR 25 September 2015 Day 3 Friday 25/09: 10:00 12:00 NEURINOX General Assembly Meeting restricted to the NEURINOX Partners and Students involved in the 2 day event Time Topic 10:00 12:00 High school and students activities : Mind Map/Web-based Timelines /Videos: final preparation 13 :00 15:00 High school and students activities: Presentation to the NEURINOX Consortium 9:30 16:00 NEURINOX General Assembly Meeting Last update 01/09/