CDC s Commitment to National Laboratory Systems to Achieve Global Health Security

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2 CDC s Commitment to National Laboratory Systems to Achieve Global Health Security Beth A Skaggs, PhD Laboratory Team Lead Division of Global Health Protection Centers for Disease Control and Prevention

3 Global Health Security Agenda We must come together to prevent, and detect and fight every kind of biological danger whether it s a pandemic like H1N1, a terrorist threat, or a treatable disease. President Barack Obama, 2011

4 Global Health Security Agenda is focused on accelerating progress toward full implementation of International Health Regulations

5 IHR (2005) a process for international collaboration and decision-making during public health emergencies reporting of specific diseases plus any potential international public health emergencies regardless of origin or source a global network of 24x7 National Focal Points (NFP) core capacities for surveillance and response for all countries at all levels (local, intermediate, national)

6 Less than 20% of the world is prepared to respond All 194 countries of the world committed to International Health Regulations June 2012 deadline only 16% fully prepared to detect and respond to pandemics

7 President Barack Obama, Sept 2014 GHSA Summit Greet ing Ebola Survivor Dr. Melvin Korkor from Liberia

8 Global Health Security Agenda Prevent avoidable catastrophes Detect threats early Respond rapidly and effectively

9 GHSA Phase Countries Ebola Affected Countries Guinea Liberia Sierra Leone At-Risk Countries (non-ghs) Benin Gambia Ghana Guinea-Bissau Mauritania Togo At-Risk Countries (GHS) Cote d'ivoire Mali Nigeria Senegal Burkina Faso GHS Bangladesh Burma Cameroon DRC Ethiopia India Indonesia Kenya Pakistan Phillippines Tanzania Uganda Vietnam

10 Action Packages to Achieve Targets Antimicrobial Resistance National Laboratory Systems Emergency Operations Centers Zoonotic Diseases Biosafety/Biosecurity Surveillance Reporting Linking Public Health with Law Enforcement and Multisectoral Rap id Response Immunization Workforce Development Medical Countermeasures and Personnel Deployment

11 National Laboratory System Action Package Five-Year Target: Real-time biosurveillance informed by a national laboratory system with effective modern point-of-care and laboratory-based diagnostics Desired Impact: National Laboratory System capable of safely and accurately detecting and characterizing pathogens casing epidemic disease from all parts of the country Lead Countries: US, Thailand, and South Africa

12 Disease Control and Response Result s Public Health Laboratory Syst em Specimens Surveillance to identify disease outbreaks

13 Intersection between Laboratory Systems and Pathogen Specific Detection Capacity Laboratory Systems Quality Management System Workforce development Equipment Maintenance Systems Supply Chain Management System Laboratory Information Systems Sample Referral Systems Policies Strengthened & Sustained Lab & Health Systems Serology Molecular Test ing Hematology Chemist r y CD4 Culture Laboratory Services Microscopy

14 Sustaining GHSA investments in National Laboratory Systems Host country ownership Local partners Stronger public health institutions Functional linkages between human and animal health

15 Technical Approach Update lab strategic plans/policies to include public health lab functions Expand lab quality improvement program Develop lab managers and leaders Enhance linkages: clinical and public health labs; human and animal labs; lab to epidemiology; lab to EOC Implement tier specific diagnostics Strengthen specimen referral network

16 Improving outbreak detection Uganda

17 Testing the Systems: Field Exercises Objectives Begin building MOH capacity to design, plan, and implement exercises not just be players Verify accuracy of laboratory testing Provide opportunity to practice enhanced EOC functions Confirm data transmission across information systems Collaboration with MoH HQ: DEO and DOD s DTRA Hanoi: ID, DGHA, by TDY DGHP and DEO External partners: WHO and Oxford

18 Global Commitment 47 countries that have committed to the Global Health Security Agenda (GHSA)

19 Ebola Response Update for 16 July 2014

20 Centers for Disease Control and Prevention 1600 Clifton Road NE, Atlanta, GA Phone: CDC-INFO ( )/TTY: Web: