Lane CR, Kwong JC, Romanes F, Easton M, Cronin K, Waters MJ, Stevens K, Schultz MB, Sherry NL, Tai A, Ballard SA, Seemann T, Stinear T & Howden BP
|
|
- Sibyl Morris
- 6 years ago
- Views:
Transcription
1 Combined genomic and epidemiological investigation of a state-wide outbreak of KPCproducing Enterobacteriaceae Lane CR, Kwong JC, Romanes F, Easton M, Cronin K, Waters MJ, Stevens K, Schultz MB, Sherry NL, Tai A, Ballard SA, Seemann T, Stinear T & Howden BP Communicable Disease Control Conference 28 th June 2017 CPE and KPC Carbapenemase producing enterobacteriaceae (CPE) Enzymes that confer resistance to carbapenem antibiotics Limited treatment - Increased morbidity and mortality Klebsiella pneumoniae carbapenemase (KPC) Large, clonal outbreaks overseas particularly K. pneumoniae 1
2 Victorian KPC - K. pneumoniae Epidemic curve, KPC positive K. pneumoniae by location at specimen collection, Victorian KPC - K. pneumoniae Patients with KPC-2 positive Klebsiella pneumoniae, by postcode of residence, Victoria
3 KPC Investigation Extent and setting of KPC transmission in Victoria? - Number of affected health services? - Inter-health service transmission? - Transmission in residential or long term care facilities, community? Detailed genomic and descriptive epidemiological investigation Methods January 2012 December 2015 Isolates referred to MDU PHL from primary laboratories Molecular characterisation Carbapenemase gene detection, multi-locus sequence typing, phylogenetic analysis Patient/NoK interview and record review Travel (since 1996), Health care contact and movements (3 years prior to detection) Qualitative interview with infection control (subset) 3
4 Isolates and Demographics 69 included patients 57 clonal complex (cc) 258 K. pneumoniae Sex, n (%) Male 33/57 (58%) Age, median (range) Years 74 (20 95) Clinical Infection 35/57 (61%) Travel KPC endemic in Greece, Israel, Italy and NE United States <50% travel since months prior: 8/57 (14%) international travel 100% inpatient hospitalisation in Australia Local transmission? 4
5 Healthcare Exposure 41 facilities, 113 data requests, 2,165 admissions 12 months prior: Median 63 inpatient days (range 0-182) 19 facilities with >1 patient 41 (72%) patients, Facility F Four major clusters Likely three importation events Sub-clusters B and C Significant differences in inpatient facilities by cluster Combined with patient movement data 5
6 Cluster D In Detail Room contacts screened Ward contact No direct patient overlap?unidentified colonised patients/environment 6
7 Infection Control Interviews Contributing factors identified by infection control staff: Missed patient contact screening (ie. only room, not ward) Absence of CPE alerts on patient records on representation Environmental contamination of patient bathrooms Lack of single bathrooms for colonised patients No centralised patient registry Difficulties in inter-facility communication Findings Limited to four discrete outbreaks in a small number of healthcare institutions Multiple importation events Unrecognised colonised patients drive transmission Identification of high risk patients (case contacts, travelers) Inter-health service communication needed Combined genomic and epidemiological data critical Systematic centralised surveillance of CPE 7
8 Epidemic curve, KPC-2 all species by travel history,
9 MDU PHL Jason Kwong Ben Howden Kerrie Stevens Acknowledgements Donna Cameron Susan Ballard DHHS Finn Romanes Marion Easton Annaleise van Diemen Suzana Talevska Brett Sutton Infection control, microbiology and record staff at affected health services Cluster A (n=4) B1 (n=28) B2 (n=16) C (n=5) Unclustered (n=8) Total (n=57) Age, yrs (median, range) 76 (74-83) 67 (20-90) 81 (52-95) 74 (58-78) 82 (73-88) 74 (20 95) Male (n, %) 1 (25) 14 (50) 11 (69) 3 (60) 4 (100) 33 (58) Colonised patients 0 (0) 4 (7) 9 (56) 2 (40) 3 (75) 18 (32) Infected patients (n, %) a 4 (100) 22 (79) 5 (31) 3 (60) 1 (25) 35 (61) Urinary tract 4 (100) 13 (46) 4 (14) 2 (40) 1 (25) 24 (42) Intrabdominal - 5 (18) (9) Pulmonary & pleural - 3 (11) 1 (4) (7) Intravascular line-related - 1 (4) (2) Skin/soft tissue (4) - 1 (2) Sepsis 1 (25) 15 (54) 3 (19) 2 (40) 1 (25) 22 (39) Comorbidities Kidney/renal disease 2 (50) 15 (54) 12 (75) 1 (20) 1 (25) 31 (54) Type 2 diabetes 2 (50) 7 (25) 8 (50) 1 (20) - 18 (32) Liver disease 1 (25) 10 (36) 1 (6) (21) Prior chemo/radiotherapy - 7 (25) 16 (13) - 1 (25) 10 (18) Antibiotic therapy > 1 month 2 (50) 8 (29) 5 (31) 3 (60) 1 (25) 19 (33) Overseas travel in prior 12 months - 1 (4) 1 (6) 2 (40) 4 (100) 8 (14) Country of travel b Greece (20) 4 (100) 5 (9) New Zealand - 1 (4) (2) Vietnam (6) 1 (20) - 2 (4) Thailand (20) - 1 (2) Hong Kong (20) - 1 (2) Overseas hospitalisation (40) 4 (100) 6 (11) a Sum may exceed total where patients report multiple sites of infection b Sum may exceed total where patients report multiple travel destinations 9
10 Infection Control Feedback Factors identified by infection control staff contributing to KPC transmission Bundled measures undertaken in every instance where ongoing transmission was halted Missed identification of patient contacts e.g. only room contacts screened, with subsequent transmission to other contacts on the same ward Use of contact screening Enhanced cleaning Isolation of cases in contact precautions Absence of permanent patient alerts for discharged patient contacts, or colonised patients requiring staff use of personal protective equipment (gloves and gown) and promotion of hand hygiene Environmental contamination of patient bathrooms Bundled measures undertaken in some instances where ongoing transmission was halted Staff cohorting Shared bathrooms for colonised patients, due to the unavailability of single bathroom facilities Lack of a central colonised patient registry, and inability of healthcare facilities to identify KPC colonised patients identified at other facilities Screening of patient transfers Notification of KPC cases and contacts to receiving facilities Environmental screening & decontamination 10
Enterobacteriaceae? ECDC EVIDENCE BRIEF. Why focus on. Update on the spread of carbapenemase-producing Enterobacteriaceae in Europe
ECDC EVIDENCE BRIEF November 2015 Update on the spread of carbapenemase-producing Enterobacteriaceae in Europe Summary of the May 2015 expert assessment The EuSCAPE project This ECDC Evidence Brief identifies
More informationBurns outbreaks - the UHB experience
Burns outbreaks - the UHB experience Dr Mark Garvey Principal Clinical Scientist in Microbiology Director of the Hospital Infection Research Laboratory Associate Director of Infection Prevention and Control
More informationEnterobacteriaceae with acquired carbapenemases, 2016
Enterobacteriaceae with acquired carbapenemases, 2016 Background The acquired or transferable (as opposed to chromosomally encoded) carbapenemases found in Enterobacteriaceae belong to three of the four
More informationBurns outbreaks - the UHB experience
Burns outbreaks - the UHB experience Dr Mark Garvey Mr Craig Bradley Principal Clinical Scientist in Microbiology Lead Nurse Infection Prevention Director of the Hospital Infection Research Laboratory
More informationCarbapenem-resistant infections on the rise in Europe Presentation by Dr Marc Sprenger, ECDC director, Brussels Press Club, 15 November 2013
ECDC DIRECTOR S PRESENTATION Carbapenem-resistant infections on the rise in Europe Presentation by Dr Marc Sprenger, ECDC director, Brussels Press Club, 15 November 2013 For the launch of the 6th European
More informationCarbapenem-resistant Enterobacteriaceae (CRE): Coming to a hospital near you?
Carbapenem-resistant Enterobacteriaceae (CRE): Coming to a hospital near you? Jon Otter, PhD FRCPath Imperial College Healthcare NHS Trust www.reflectionsipc.com @jonotter Contents What s the problem?
More informationInfection control in Aged Residential Care Facilities. Dr Sally Roberts Clinical Advisor for IP&C Service, ADHB
Infection control in Aged Residential Care Facilities Dr Sally Roberts Clinical Advisor for IP&C Service, ADHB Background Endemic infections Epidemic infections Managing outbreaks Administrative measures
More informationInfection Control Strategies to Avoid Carbapenam Resistance in Hospitals. Victor Lim International Medical University Malaysia
Infection Control Strategies to Avoid Carbapenam Resistance in Hospitals Victor Lim International Medical University Malaysia Outline of Lecture 1. Carbapenam resistance 2. Epidemiology of carbapenam resistance
More informationGUIDE TO INFECTION CONTROL IN THE HOSPITAL. Carbapenem-resistant Enterobacteriaceae
GUIDE TO INFECTION CONTROL IN THE HOSPITAL CHAPTER 47: Carbapenem-resistant Enterobacteriaceae Authors E-B Kruse, MD H. Wisplinghoff, MD Chapter Editor Michelle Doll, MD, MPH) Topic Outline Key Issue Known
More informationCarbapenemase Producing Enterobacteriaceae: Screening
Carbapenemase Producing Enterobacteriaceae: Screening Dr David Harvey Consultant Microbiology and Infection Prevention and Control Nov 2015 Aims Is CPE a problem? Does screening have the potential to help?
More informationAppendix B: Provincial Case Definitions for Reportable Diseases
Ministry of Health and Long-Term Care Infectious Diseases Protocol Appendix B: Provincial Case Definitions for Reportable Diseases Disease: Carbapenemase-producing Enterobacteriaceae (CPE) infection or
More informationEnterobacteriaceae with acquired carbapenemases, 2015
Enterobacteriaceae with acquired carbapenemases, 2015 Background The acquired or transferable (as opposed to chromosomally encoded) carbapenemases found in Enterobacteriaceae belong to three of the four
More informationEarly identification and management of CPE risk in the Emergency Department.
Early identification and management of CPE risk in the Emergency Department. Jo-Anne McShane 1, Andrew Maclean 1,2, Leanne Houston 4, Helen Marquand 4, Madeleine Smith 1,Mary O Reilly 1,2,3 Acknowledgements:
More informationThe Carbapenemase Producing Enterobacteriaceae (CPE) Epidemic Why it matters? What it is? What Can You Do About It?
The Carbapenemase Producing Enterobacteriaceae (CPE) Epidemic Why it matters? What it is? What Can You Do About It? Martin Cormican National Lead for Health Care Associated Infection and Antimicrobial
More information1. INTRODUCTION. 1.1 Standard Precautions
1. INTRODUCTION 1.1 Standard Precautions Standard precautions, originally known as universal precautions, are essential components in preventing the transmission of infectious diseases in the healthcare
More informationThe Public Health Benefit of CRE Colonization Testing
The Public Health Benefit of CRE Colonization Testing Allison C Brown, PhD MPH Team Lead, AR Capacities and Special Studies Division of Healthcare Quality Promotion CDC Carbapenem Resistance Serious threat
More informationPublic Health Surveillance for Multi Drug Resistant Organisms in Orange County
Public Health Surveillance for Multi Drug Resistant Organisms in Orange County Matt Zahn, MD Medical Director Epidemiology and Assessment Orange County Public Health Antimicrobial Mechanisms of Action
More informationInfection Prevention & Control Core Skills Level 2
Infection Prevention & Control Core Skills Level 2 Learning outcomes Risk assessment of patients Critical examination of the situation MRSA, CDT & CPE Ongoing challenges future-proofing infection control
More informationInfection control in aged care facilities 3 rd February 2019
Infection control in aged care facilities 3 rd February 2019 A/Prof. Paul Griffin FRACP, FRCPA, FACTM, AFACHSM, FIML, MBBS, BSc(Hons) Infectious Diseases Physician and Clinical Microbiologist Director
More informationEmerging Infections, Outbreaks, and Steps of an Outbreak Investigation Across the Healthcare Continuum
Emerging Infections, Outbreaks, and Steps of an Outbreak Investigation Across the Healthcare Continuum Jennifer MacFarquhar, MPH, BSN, RN, CIC Heather Dubendris, MSPH North Carolina Division of Public
More informationGuidance on screening and confirmation of carbapenem resistant Enterobacteriacae (CRE) December 12, 2011
Guidance on screening and confirmation of carbapenem resistant Enterobacteriacae (CRE) December 12, 2011 Objectives: To discuss the guidelines for detection of CRE in the laboratory setting. To review
More informationBefore an outbreak - what to do after first MDR Gram-negatives enter your hospital?
Before an outbreak - what to do after first MDR Gram-negatives enter your hospital? Jon Otter, PhD FRCPath Imperial College London j.otter@imperial.ac.uk @jonotter Blog: www.reflectionsipc.com Slides:
More informationEmerging Infections, Outbreaks, and Steps of an Outbreak Investigation Across the Healthcare Continuum
Emerging Infections, Outbreaks, and Steps of an Outbreak Investigation Across the Healthcare Continuum Jennifer MacFarquhar, MPH, BSN, RN, CIC Heather Dubendris, MSPH North Carolina Division of Public
More informationUnder the radar. Two prolonged outbreaks of carbapenemase-producing Enterobacteriaceae (CPE) at a tertiary hospital in Canberra, Australia
Under the radar Two prolonged outbreaks of carbapenemase-producing Enterobacteriaceae (CPE) at a tertiary hospital in Canberra, ustralia lexandra armor, Kathryn Daveson, Karina Kennedy & David Harley No
More informationEmergence of carbapenemase-producing Enterobacteriaceae in France, 2004 to 2011.
Emergence of carbapenemase-producing Enterobacteriaceae in France, 2004 to 2011. Sophie Vaux, Anne Carbonne, Jean-Michel Thiolet, Vincent Jarlier, Bruno Coignard, the RAISIN and Expert Laboratories Group
More informationThe Year in Infection Control
The Year in Infection Control Andie Lee Departments of Infectious Diseases and Microbiology Royal Prince Alfred Hospital Sydney, Australia 1 1.223 million Pubmed publications last 12 months 2 Selection
More information10/4/16. mcr-1. Emerging Resistance Updates. Objectives. National Center for Emerging and Zoonotic Infectious Diseases. Alex Kallen, MD, MPH, FACP
National Center for Emerging and Zoonotic Infectious Diseases Emerging Resistance Updates Alex Kallen, MD, MPH, FACP Lead Antimicrobial Resistance and Emerging Pathogens Team Prevention and Response Branch
More informationRecommendations for the Management of Carbapenem- Resistant Enterobacteriaceae (CRE) in Acute and Long-term Acute Care Hospitals
Recommendations for the Management of Carbapenem- Resistant Enterobacteriaceae (CRE) in Acute and Long-term Acute Care Hospitals Minnesota Department of Health 11/2011 Infectious Disease Epidemiology,
More informationSubject: CPE information for healthcare workers For: Healthcare workers
Fact sheet 3 of 6 Subject: CPE information for healthcare workers For: Healthcare workers What can be done to prevent healthcare associated infection? It is really difficult to completely stop bugs from
More informationEmergence of Klebsiella pneumoniae ST258 with KPC-2 in Hong Kong. Title. Ho, PL; Tse, CWS; Lai, EL; Lo, WU; Chow, KH
Title Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Hong Kong Author(s) Ho, PL; Tse, CWS; Lai, EL; Lo, WU; Chow, KH Citation International Journal Of Antimicrobial Agents, 2011, v. 37 n. 4, p.
More informationClin Microbiol Infect Feb;21(2):e11-3. doi: /j.cmi Epub 2014 Oct 29.
This Accepted Author Manuscript (AAM) is copyrighted and published by Elsevier. It is posted here by agreement between Elsevier and the University of Turin. Changes resulting from the publishing process
More informationEpidemiology of the β-lactamase resistome among Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae in the Chicago region
Epidemiology of the β-lactamase resistome among Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae in the Chicago region Michael Y. Lin MD MPH 1, Karen Lolans BS 1, Rosie D. Lyles,
More informationGuidance for Control of Infections with Carbapenem-Resistant or Carbapenemase-Produc... Producing Enterobacteriaceae in Acute Care Facilities
Page 1 of 6 Weekly March 20, 2009 / 58(10);256-260 Guidance for Control of Infections with Carbapenem-Resistant or Carbapenemase- Producing Enterobacteriaceae in Acute Care Facilities Infection with carbapenem-resistant
More informationDiagnosis of CPE: time to throw away those agar plates? Jon Otter, PhD FRCPath Guy s and St. Thomas NHS Foundation Trust / King s College London
Diagnosis of CPE: time to throw away those agar plates? Jon Otter, PhD FRCPath Guy s and St. Thomas NHS Foundation Trust / King s College London Disclosures I am employed part-time by Bioquell I have research
More informationHOSPITAL INFECTION CONTROL
HOSPITAL INFECTION CONTROL Objectives To be able to define hospital acquired infections discuss the sources and routes of transmission of infections in a hospital describe methods of prevention and control
More informationCandida auris: an Emerging Hospital Infection
National Center for Emerging and Zoonotic Infectious Diseases Candida auris: an Emerging Hospital Infection Paige Armstrong MD MHS Epidemic Intelligence Service Officer Mycotic Diseases Branch Association
More informationLourdes Hospital Infection Prevention and Control
Lourdes Hospital Infection Prevention and Control Lourdes Infection Prevention Program Ultimate goal: To protect the patient To protect the healthcare workers, visitors and others in the environment To
More informationDr Emily Macnaughton Consultant Microbiologist & Infection Control Doctor MB ChB FRCPath
Dr Emily Macnaughton Consultant Microbiologist & Infection Control Doctor MB ChB FRCPath Defining infection Ways to control infection In the community In the hospital Problem infections Future predictions
More informationNorovirus Outbreak in a Children s Hospital. Jennifer Adams, MT, MPH, CIC April 23, 2015
Norovirus Outbreak in a Children s Hospital Jennifer Adams, MT, MPH, CIC April 23, 2015 Objectives Discuss the epidemiology, symptoms, and transmission of norovirus. Identify key infection control activities
More informationCarbapenemase Producing Enterobacteriaceae (CPE)
Carbapenemase Producing Enterobacteriaceae (CPE) Understanding The Public Health Emergency Professor Martin Cormican HSE National Lead for Health Care Associated Infection and Antimicrobial Resistance
More informationThe role of an AMR reference laboratory
The role of an AMR reference laboratory Professor Neil Woodford Antimicrobial Resistance & Healthcare Associated Infections (AMRHAI) Reference Unit Crown copyright Primary purpose: regional AMR threats
More informationInfluenza Outbreak Control Measure Trigger Tool for Care Homes
Influenza Outbreak Control Measure Trigger Tool for Care Homes To be used on instruction of your Health Protection Teams (HPT) The control measures in this tool are in addition to Standard Infection Control
More informationCarbapenemase Producing Organisms. Manal Tadros Medical Microbiologist Fraser Health Authority
Carbapenemase Producing Organisms Manal Tadros Medical Microbiologist Fraser Health Authority 1 Objectives Discuss Laboratory detection of CPO Summarize the Epidemiology of CPO in Fraser Health Authority
More informationEpidemiology of ESBL in hospitals and in the community
Epidemiology of ESBL in hospitals and in the community Dietrich Mack Chair of Medical Microbiology and Infectious Diseases The School of Medicine - University of Wales Swansea P R I F Y S G O L C Y M R
More informationSpread of carbapenems resistant Enterobacteriaceae in South Africa; report from National Antimicrobial Resistance Reference Laboratory
Spread of carbapenems resistant Enterobacteriaceae in South Africa; report from National Antimicrobial Resistance Reference Laboratory Olga Perovic*, Ashika Singh-Moodley, Samantha Iyaloo 5 th November
More informationPolicy Objective. This policy applies to all staff employed by NHS Greater Glasgow & Clyde and locum staff on fixed term contracts.
1 of 9 Policy Objective To ensure that Healthcare Workers are aware of the actions and precautions necessary to minimise the risk of outbreaks and the importance of diagnosing patients clinical conditions
More informationIPAC PANA April 28, Sandra Callery RN MHSc CIC
IPAC PANA April 28, 2015 Sandra Callery RN MHSc CIC World Youth Day - Toronto 2002 World Youth Day Downsview Park 2002 #1 issue =Heat-related illness. A rehydration ward was established on-site (300 beds)
More informationWHAT S INFECTIOUS and HOT: 2014
WHAT S INFECTIOUS and HOT: 2014 Gary Garber MD FRCPC FACP FIDSA CCPE Medical Director-Infection Prevention and Control Professor-Division of Infectious Diseases Ottawa Hospital/U Ottawa OUTBREAK ALERT:
More informationBlood-borne Virus Infections in Health Care Workers: Victorian Lookback Experiences
Blood-borne Virus Infections in Health Care Workers: Victorian Lookback Experiences Dr Jessica Rotty, Dr Brett Sutton, Dr Mihaela Ivan, Adam Hamilton, Jay Healy, Nasra Higgins, Rachel Coutts, Rachel M
More informationPrevent Measles Example of Fact sheet for health workers in Fiji
Prevent Measles Example of Fact sheet for health workers in Fiji This example of a practical fact sheet can be adapted in other Pacific Island countries and territories to help raise awareness and prevent
More informationTitle/Description: Outbreak Investigation Guidelines Department: All Departments. Effective Date: 4/97 REVISED: 1/00, 5/08 I.
Title/Description: Outbreak Investigation Guidelines Department: All Departments Personnel: All Personnel Effective Date: 4/97 REVISED: 1/00, 5/08 I. PURPOSE At Springhill Medical Center (SMC) an outbreak
More informationRespiratory Viruses Policy
Respiratory Viruses Policy Page 1 of 8 Document Control Sheet Name of document: Version: 3 Status: Owner: File location / Filename: Respiratory viruses policy Date of this version: February 2013 Infection
More informationHealthcare-Associated Infections Across the Spectrum of Care
MODULE 9: HEALTHCARE-ASSOCIATED INFECTIONS ACROSS THE SPECTRUM OF CARE Healthcare-Associated Infections Across the Spectrum of Care Susan E. Coffin, MD, MPH UPENN School of Medicine, Department of Pediatrics
More informationEducational Workshops 2016
Educational Workshops 2016 Keynote CPE Screening We are grateful to Dr Andrew Dodgson, Consultant Microbiologist, Public Health England and Central Manchester Hospitals NHS Foundation Trust Terminology
More informationCohorting in Acute Care Impact on LTC Resident Repatriation During an Outbreak
Cohorting in Acute Care Impact on LTC Resident Repatriation During an Outbreak Gary E Garber MD FRCPC FACP Medical Director- IPAC Public health Ontario Objectives Why talk about cohorting? Cohorting when
More informationNCCID RAPID REVIEW. 1. What are the case definitions and guidelines for surveillance and reporting purposes?
NCCID RAPID REVIEW 1. What are the case definitions and guidelines for surveillance and reporting purposes? Middle East Respiratory Syndrome Coronavirus: Ten Questions and Answers for Canadian Public Health
More informationCarbapenemase producing Enterobacterales (CPE) in HSE acute hospitals
Carbapenemase producing Enterobacterales (CPE) in HSE acute hospitals Monthly report on July 2018 data for the National Public Health Emergency Team (NPHET) Executive summary of the latest available data
More informationAVIAN INFLUENZA. Frequently Asked Questions and Answers
PENINSULA HEALTH AVIAN INFLUENZA Frequently Asked Questions and Answers Q. What is avian influenza? Answer: Avian influenza is an infectious disease of birds caused by type A strains of the influenza virus.
More informationGlobal Epidemiology of Carbapenem- Resistant Enterobacteriaceae (CRE)
Global Epidemiology of Carbapenem- Resistant Enterobacteriaceae (CRE) Mitchell J. Schwaber, MD MSc Director, National Center for Infection Control Ministry of Health State of Israel November 27, 2012 1
More informationWhole genome sequencing & new strain typing methods in IPC. Lyn Gilbert ACIPC conference Hobart, November 2015
Whole genome sequencing & new strain typing methods in IPC Lyn Gilbert ACIPC conference Hobart, November 2015 Why do strain typing? Evolution, population genetics, geographic distribution 2 Why strain
More informationPalliative Care and End of Life Care
Palliative Care and End of Life Care Relevant Data and References Victorian Population 1 Total Victorian Population as at June 2016 was 6.1 million (6,179,249) Victorian 60 plus population as at June 2016
More informationIsolation Precautions in Clinics
Purpose Audience General principles Possible Exposures To define isolation precautions in a clinic setting. Clinics Isolation status should be determined primarily by the suspected disease and/or pathogen.
More informationCurrent and Emerging Legionella Diagnostics
Current and Emerging Legionella Diagnostics Nicole Wolter Centre for Respiratory Diseases and Meningitis (CRDM) National Institute for Communicable Diseases nicolew@nicd.ac.za 7 th FIDSSA Conference, Cape
More informationScreening for multiple antibiotic resistant Gram negative bacteria (MR-GNB) in NICU: Yes or No?
Screening for multiple antibiotic resistant Gram negative bacteria (MR-GNB) in NICU: Yes or No? Dr Abid Hussain Consultant Microbiologist & Paediatric Liaison Lead PHE Birmingham Public Health Laboratory
More informationCarbapenemases in Enterobacteriaceae: Prof P. Nordmann Bicêtre hospital, South-Paris Med School
Carbapenemases in Enterobacteriaceae: 2012 Prof P. Nordmann Bicêtre hospital, South-Paris Med School March 21, 2012 Trends in Molecular Medecine NDM IMP OXA-48 KPC VIM ALERT VI M KPC KPC NDM I MP OXA-
More informationSOP Objective To provide Healthcare Workers (HCWs) with details of the precautions necessary to minimise the risk of RSV cross-infection.
Page 1 of 11 SOP Objective To provide Healthcare Workers (HCWs) with details of the precautions necessary to minimise the risk of RSV cross-infection. This SOP applies to all staff employed by NHS Greater
More informationNovel Coronavirus 2012
Novel Coronavirus 2012 Susan I. Gerber, MD Respiratory Virus Program Division of Viral Diseases National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention Jan.
More informationDiagnosis, Management, and Prevention of Clostridium difficile infection in Long-Term Care Facilities: A Review
Diagnosis, Management, and Prevention of Clostridium difficile infection in Long-Term Care Facilities: A Review October 18, 2010 James Kahn and Carolyn Kenney, MSIV Overview Burden of disease associated
More informationUnwell returned traveller
Unwell returned traveller Full Title of Guideline: Author (include email and role): Division & Speciality: Scope (Target audience, state if Trust wide): Review date (when this version goes out of date):
More informationUrinary Catheters. Prevalence of Infections
Urinary Catheterisation Urinary catheterisation is defined as an intervention to enable the emptying of the bladder by insertion of a catheter. Catheters can be short term less than 28 days or long term
More informationInfection Control Road Show 2011 Outbreak Management
Infection Control Road Show 2011 Outbreak Management Today s Agenda LTCH Road Show Road Map for the day How can you, the management team, support infection prevention and control and promote infection
More informationInfluenza Surveillance to Inform Decision Making
Influenza Surveillance to Inform Decision Making Ms Kate Pennington Epidemiologist Assistant Director, Vaccine Preventable Diseases Surveillance Office of Health Protection Department of Health and Ageing
More informationPreventing Healthcare-associated Infections in Resource-limited Settings
Preventing Healthcare-associated Infections in Resource-limited Settings Michael Bell, M.D. Division of Healthcare Quality Promotion Centers for Disease Control and Prevention Challenges for Infection
More informationThe Antibiotic Resistance Laboratory Network
The Antibiotic Resistance Laboratory Network 1 Antibiotic Resistance in the United States Sickens >2 million people per year Kills at least 23,000 people each year Plus 15,000 each year from C. difficile
More informationHOSPITAL EPIDEMOLOGY AND INFECTION CONTROL: STANDARD AND TRANSMISSION-BASED ISOLATION
Appendix 1: Carbapenem-Resistant Enterobacteriacaea (CRE) I. Definition: 2015 CDC definition of CRE are Enterobacteriaceae 1 that are: A. Resistant to any carbapenem antimicrobial (i.e., minimum inhibitory
More informationSARS Infection Control in Healthcare Settings
SARS Infection Control in Healthcare Settings William A. Rutala, Ph.D., M.P.H. University of North Carolina (UNC) Hospitals and UNC School of Medicine Infection Control Considerations Hospitals must protect
More informationLEARNING FROM OUTBREAKS: SARS
LEARNING FROM OUTBREAKS: SARS IFIC - APECIH 2017 KATHRYN N. SUH, MD, FRCPC 29 SEPTEMBER 2017 www.ottawahospital.on.ca Affiliated with Affilié à SEVERE ACUTE RESPIRATORY SYNDROME (SARS) Nov 2002 southern
More informationHealth Board Logo. Post SARS Outbreak Surveillance. Report of possible or probable cases (Form version 1) February 11 th 2004
Post SARS Outbreak Surveillance Report of possible or probable cases (Form version 1) February 11 th 2004 This form is to be used for persons who fit the surveillance case definition of possible or probable
More informationRegional Emergence of VIM producing carbapenem resistant Pseudomonas aeruginosa (VIM CRPA)
National Center for Emerging and Zoonotic Infectious Diseases Regional Emergence of VIM producing carbapenem resistant Pseudomonas aeruginosa (VIM CRPA) Chris Prestel, MD Epidemic Intelligence Service
More informationViral Agents of Paediatric Gastroenteritis
Viral Agents of Paediatric Gastroenteritis Dr Carl Kirkwood -------------------- Enteric Virus Research Group Murdoch Childrens Research Institute Royal Children s Hospital Victoria. WHO Collaborating
More informationConfronting Ebola. Keeping NY patients and healthcare workers safe and healthy
Confronting Ebola Keeping NY patients and healthcare workers safe and healthy All materials provided by Centers for Disease Control and Prevention. October 16, 2014 What You Need to Know about Ebola The
More informationIntroduction to the identification and management of carbapenemase producing Enterobacteriaceae (CPE)
Introduction to the identification and management of carbapenemase producing Enterobacteriaceae (CPE) Jon Otter, Research Fellow at Centre for Clinical Infection and Diagnostics Research (CIDR), King's
More informationInfluenza. Dr Bhakti Vasant Public Health Physician Metro South Public Health Unit. Metro South Public Health Unit
Metro South Public Health Unit Influenza Dr Bhakti Vasant Public Health Physician Metro South Public Health Unit Source of image: CDC. Influenza images. Available from URL: https://www.cdc.gov/flu/images/h1
More informationLegionellosis Outbreak-Genesee County, June, 2014 March, Summary Analysis
Legionellosis Outbreak-Genesee County, June, 2014 March, 2015 Summary Analysis Michigan Department of Health and Human Services Genesee County Health Department (This report was edited on January 15, 2016
More informationAppendix C. RECOMMENDATIONS FOR INFECTION CONTROL IN THE HEALTHCARE SETTING
Appendix C. RECOMMENDATIONS FOR INFECTION CONTROL IN THE HEALTHCARE SETTING Infection Control Principles for Preventing the Spread of Influenza The following infection control principles apply in any setting
More informationInfection Preventionist Series
Infection Preventionist Series Webinar 5: Frequent Citations: What Are We Missing? Diane Dohm MT, IP, CIC, CPHQ MetaStar April 3, 2018 Infection Preventionist Series Surveillance What data should we collect?
More informationONE IS A PROBLEM, TWO IS AN OUTBREAK: DETECTING AND RESPONDING TO OUTBREAKS IN LONG-TERM CARE FACILITIES. May 17, 2018
ONE IS A PROBLEM, TWO IS AN OUTBREAK: DETECTING AND RESPONDING TO OUTBREAKS IN LONG-TERM CARE FACILITIES May 17, 2018 Jennifer MacFarquhar, MPH, BSN, RN, CIC Moderator: Wanda Lamm, RN, BSN, CIC, FAPIC
More informationComplications Audit of Urological Issues in Spinal Cord Injury Evaluation Study (CAUSES)
Complications Audit of Urological Issues in Spinal Cord Injury Evaluation Study (CAUSES) Dr Andrew Nunn Ms Melinda Millard Ms Janette Alexander Ms Louise MacLellan Ms Catherine Byrne 23 rd September 2015
More informationManagement of Gastroenteritis Outbreaks. Approval Signature: Date of Approval: March 4, 2010 Review Date: March 2013
Personal Care Home/Long Term Care Facility Infection Prevention and Control Program Operational Directive Management of Gastroenteritis Outbreaks Approval Signature: Date of Approval: March 4, 2010 Review
More informationNavigating Through Current and Emerging Issues in Outbreaks
Navigating Through Current and Emerging Issues in Outbreaks 7th GCC Conference on Infection Prevention and Control December 1-3, 2013 Kuwait City, Kuwait William R. Jarvis, M.D. Jason and Jarvis Associates,
More informationUniversity of Groningen
University of Groningen Carbapenemase-producing Enterobacteriaceae in Europe Albiger, B.; Glasner, Corinna; Struelens, M. J.; Grundmann, H.; Monnet, D. L.; European Survey Carbapenemase Published in: Eurosurveillance
More informationHealthcare-associated infections acquired in intensive care units
SURVEILLANCE REPORT Annual Epidemiological Report for 2015 Healthcare-associated infections acquired in intensive care units Key facts In 2015, 11 788 (8.3%) of patients staying in an intensive care unit
More informationManagement of FLI in care homes. Fiona Morris (HPN) September 2018
Management of FLI in care homes Fiona Morris (HPN) September 2018 Aims and Objectives Overview of role of Public Health Completion of risk assessment Review IPC advice Consider use of Antiviral Medication
More informationNational Center for Emerging and Zoonotic Infectious Diseases The Biggest Antibiotic Resistance Threats
National Center for Emerging and Zoonotic Infectious Diseases The Biggest Antibiotic Resistance Threats Jean B. Patel, PhD, D(ABMM) Science Lead, Antibiotic Resistance and Coordination Unit Centers for
More informationInvestigation of a Neisseria meningitidis Serogroup A Case in the Meningitis Belt. January 2017
January 2017 Investigation of a Neisseria meningitidis Serogroup A Case in the Meningitis Belt Introduction Since the progressive introduction of meningococcal serogroup A conjugate vaccine (MACV) in the
More informationDiarrhoeal disease outbreak investigation in Guadalcanal and Honiara Provinces, September November 2008
Diarrhoeal disease outbreak investigation in Guadalcanal and Honiara Provinces, September November 2008 This article is an outcome of the field epidemiology or Data for Decision Making (DDM) training undertaken
More informationTransmission of Infectious Disease on Aircraft
Transmission of Infectious Disease on Aircraft Wing Commander Martin Connor MSc MB ChB MRCPath MFPHM DTM&H RAF Consultant in Microbiology and Communicable Diseases RAF Centre of Aviation Medicine Infectious
More informationPrevention of Healthcare- Associated Gastrointestinal Infections Michael A. Borg and Rodianne Abela
Chapter 19 Prevention of Healthcare- Associated Gastrointestinal Infections Michael A. Borg and Rodianne Abela Key Points Noroviruses are the commonest cause of healthcare-associated gastroenteritis. Isolation
More informationUpdated situation of dengue fever in Hong Kong. Surveillance and Epidemiology Branch, Centre for Health Protection 31 August 2018
Updated situation of dengue fever in Hong Kong Surveillance and Epidemiology Branch, Centre for Health Protection 31 August 2018 Background In Hong Kong, dengue fever (DF) is a notifiable disease under
More informationβ- Lactamase Gene carrying Klebsiella pneumoniae and its Clinical Implication
Prevalence of Carbapenem-Hydrolyzing β- Lactamase Gene carrying Klebsiella pneumoniae and its Clinical Implication David Alcid M.D Balaji Yegneswaran M.D. Wanpen Numsuwan Introduction Klebsiella pneumoniae
More information