Vaccination. Artificially induced specific adaptive immunity
|
|
|
- Aron Harvey
- 5 years ago
- Views:
Transcription
1 Vaccination Artificially induced specific adaptive immunity
2 Is vaccination useful?
3
4 Good vaccine characteristics
5 Live attenuated vaccine Microbes are weak but alive Mimics natural immunization (infection): strong cellular and humoral immune response Limitations /downsides: Possibility of mutation (back) to virulent forms Not absolutely safe for everyone Requires cooling during storage Examples: morbilli, parotitis, varicella,
6 Inactivated (killed) vaccines Dead microbes: - whole or fractionated; killed by chemicals, temperature, irradiation Microbes can not mutate into virulent form Do not require cooling during storage Limitations /downsides: Weaker immune response in comparison to live vaccines (revaccinations (booster dose) are needed) Examples: influenza, polio, pertussis, cholera, typhoid, diphteria, tetanus,
7 Recombinant vaccines Antigens (epitopes) that are the most potent in stimulating immune response Usually contains several antigens Recombinant DNA technology is used for genetic cloning Limitations /downsides: - It is not easy to determine the most immunogenic antigens for the population Examples: HBV, HCV, Ebola?, HIV?,
8 Genetic engeneering
9 DNA vaccines
10 DNA vaccines
11 Production of recombinant HBV vaccine
12 Flu vaccine production Recombinant DNA vaccine Traditional method (with technology based on chicken eggs 5 to 6 months in average is needed for mass production of influenza vaccine)
13 Adjuvans Adjuvans are added to vaccines to stimulate immune response for specific antigen, while they do not induce specific immunity themselves Immune stimulation mechanism of adjuvans: Increase availability of antigen in the blood and tissue Increase adsorptions of antigen via APC Activate macrophages and lymphocytes Stimulate the production of cytokines
14 Types of adjuvans Anorganic components: aluminium salts, aluminium hydroxide, aluminium phosphate, calcium phosphate and hydroxide Mineral oils: paraffin oil (for Depo vaccines) Bacterial products: dead bacteria Bordetella pertussis, Mycobacterium bovis, toxoids Nonbacterial organic compounds: skvalen, thimerosal Substances that facilitate delivery: detergens (Quil A) Plant saponins: quillaja, Soy, Polygala senega, Cytokins: IL-1, IL-2, IL-12 Combination: Freund's complete adjuvans (exicated M. tuberculosis emulsified in mineral oil) Other: (adjuvant 65) peanut oil
15 New vaccines development Develop better adjuvanses ISCOMs (Immune Stimulatory Complexes) transfer peptides for MHC I presentation Mucose adjuvans (modified pertusis toxin) The aim is to act on APC during simultaneous admission of cytokines Developing nasal or oral vaccines (molecular pharming)
16 Vaccine Adverse Reactions Adverse reaction is extraneous effect caused by vaccine (side effect) Adverse event: any medical event following vaccination (may be true adverse reaction or may be only coincidental) Local adverse reactions: pain, swelling, redness at site of injection (occur within a few hours of injection; usually mild and selflimited) Systemic adverse reactions: fever, malaise, headache (nonspecific; may be unrelated to vaccine) Severe allergic: (anaphylaxis) due to vaccine or vaccine component rare risk minimized by screening
17 Contraindications and Precautions Contraindication to Vaccination A condition that increases the likelihood of a serious adverse reaction to a vaccine for a patient with that condition Precaution A condition in a recipient that might increase the chance or severity of an adverse reaction, or Might compromise the ability of the vaccine to produce immunity
18 Contraindications and precautions for vaccination Condition Live Inactivated Allergy to component C C Encephalopathy --- C Pregnancy C V* Immuno-suppression C V Severe illness P P Recent blood product P** V C=contraindication P=precaution V=vaccinate if indicated *except HPV **MMR and varicella containing (except zoster vaccine) only
19 Permanent contraindications to vaccination Severe allergic reaction to a vaccine component or following a prior dose Encephalopathy not due to another identifiable cause occurring within 7 days of pertussis vaccination Severe combined immunodeficiency (rotavirus vaccine) History of intussusception (rotavirus vaccine)
20 Literature: Epidemiology and Prevention of Vaccine- Preventable Diseases: The Pink Book: Course Textbook - 13th Edition (2015) index.html
Vaccination-Strategies
Vaccination-Strategies Active immunity produced by vaccine Immunity and immunologic memory similar to natural infection but without risk of disease. General Rule: The more similar a vaccine is to the disease-causing
General Recommendations. General Best Practice Guidelines 9/10/2018. General Best Practice Guidelines for Immunization Part 1
Centers for Disease Control and Prevention National Center for Immunization and Respiratory Diseases General Best Practice Guidelines for Immunization Part 1 Chapter 2 September 2018 Photographs and images
VACCINATION. DR.FATIMA ALKHALEDY M.B.Ch.B;F.I.C.M.S/C.M.
VACCINATION DR.FATIMA ALKHALEDY M.B.Ch.B;F.I.C.M.S/C.M. IMMUNIZATION Immunization is defined as the procedure by which the body is prepared to fight against a specific disease. It is used to induce the
Please read Chapters 5, 6 and 7 of your vaccine text for next Wednesday s lecture. Chapters 9, 17 and 8 for next Friday s lectures
Valerie Daggett Please read Chapters 5, 6 and 7 of your vaccine text for next Wednesday s lecture Chapters 9, 17 and 8 for next Friday s lectures ppt files for first 2 lectures Past exams Principles of
Gene Vaccine Dr. Sina Soleimani
Gene Vaccine Dr. Sina Soleimani Human Viral Vaccines Quality Control Laboratory (HVVQC) Titles 1. A short Introduction of Vaccine History 2. First Lineage of Vaccines 3. Second Lineage of Vaccines 3. New
By:Reham Alahmadi NOV The production of antibodies and vaccination technology
By:Reham Alahmadi NOV 2018 The production of antibodies and vaccination technology Antibody Production The blood contains two types of white blood cell or leukocyte Phagocytes ingest bacteria by endocytosis
Vaccines and other immunological antimicrobial therapy 1
Vaccines and other immunological antimicrobial therapy 1 Vaccines Vaccine: a biological preparation that provides active acquired immunity to a particular disease. Vaccine typically contains an agent that
General Recommendations on Immunization
General Recommendations on Immunization Epidemiology and Prevention of Vaccine- Preventable Diseases National Immunization Program enters for Disease ontrol and Prevention Revised January 2006 Issues Regarding
Immunity and how vaccines work
Immunity and how vaccines work Dr Mary O Meara National Immunisation Office Objectives of session An understanding of the following principles Overview of immunity Different types of vaccines and vaccine
Trends in vaccinology
Trends in vaccinology Mathieu Peeters, MD Joint Conference of European Human Pharmacological Societies and Joint Conference of European Human Pharmacological Societies and 20th Anniversary of AGAH March
Principles of Vaccination
Immunology and Vaccine-Preventable Diseases Immunology is a complicated subject, and a detailed discussion of it is beyond the scope of this text. However, an understanding of the basic function of the
Biotechnology-Based Vaccines. Dr. Aws Alshamsan Department of Pharmaceutics Office: AA87 Tel:
Biotechnology-Based Vaccines Dr. Aws Alshamsan Department of Pharmaceutics Office: AA87 Tel: 4677363 aalshamsan@ksu.edu.sa Objectives of this lecture By the end of this lecture you will be able to: 1.
IMMUNIZATION IN CHILDREN WITH CANCER
SIOP PODC Supportive Care Education Presentation Date: 05 th September 2014 Recording Link at www.cure4kids.org: http://www.cure4kids.org/ums/home/conference_rooms/enter.php?room=p2xokm5imdj Email: ahmed.naqvi@sickkids.ca
APEC Guidelines Immunizations
Pregnancy provides an excellent opportunity to enhance a woman s protection against disease and to provide protection to the neonate during the first 3 to 6 months of life. Women of childbearing age should
Copyright regulations Warning
COMMONWEALTH OF AUSTRALIA Copyright regulations 1969 Warning This material has been reproduced and communicated to you by or on behalf of the University of Melbourne pursuant to part VB of the Copyright
Immunization. Historical point
Immunization Historical point In 1796 Edward Jenner s use of material from cowpox pustules to provide protection against smallpox. Louis Pasteur s 1885 rabies was the next to make an impact on human disease
9/10/2018. Principles of Vaccination. Immunity. Antigen. September 2018
Centers for Disease Control and Prevention National Center for Immunization and Respiratory Diseases Principles of Vaccination September 2018 Chapter 1 September 2018 Photographs and images included in
Immunization (I) Dr. Aws Alshamsan Department of Pharmaceu5cs Office: AA87 Tel:
Immunization (I) Dr. Aws Alshamsan Department of Pharmaceu5cs Office: AA87 Tel: 4677363 aalshamsan@ksu.edu.sa Objectives of this lecture By the end of this lecture you will be able to: 1 Realize the significance
The World Health Organization (WHO) estimate that vaccination averts 2-3 million deaths per year (in all age groups), and up to 1.
Vaccination The World Health Organization (WHO) estimate that vaccination averts 2-3 million deaths per year (in all age groups), and up to 1.5 million children die each year due to diseases which could
Immunity & How Vaccines Work
Immunity & How Vaccines Work Immunisation Study Day 30 th November 2016 Talk given today by Dr. Mary Fitzgerald Learning outcome To be able to describe in outline the immune system and how vaccines work
Immunizations Offered
Immunizations Offered Most vaccines commercially available in the United States are available at the health clinic. A partial list of available vaccines follows. For more information about specific vaccines
3. Lymphocyte proliferation (fig. 15.4): Clones of responder cells and memory cells are derived from B cells and T cells.
Chapter 15 Adaptive, Specific Immunity and Immunization* *Lecture notes are to be used as a study guide only and do not represent the comprehensive information you will need to know for the exams. Specific
Chapter 1. Full file at
Chapter 1 1. Which is the best definition of immunity? Answer: B A. The state of having been exposed to a pathogen repeatedly B. The state of being resistant to reinfection with a pathogen C. When an individual
VACCINATION PASSIVE IMMUNITY
VACCINATION Immunization is one of the most beneficial and cost-effective disease prevention measures. As a result of effective and safe vaccines, smallpox has been eradicated, polio is close to worldwide
2/20/2019. The need for adult vaccinations. Update on Adult Immunizations. The Need for Adult Vaccinations. Objectives:
The need for adult vaccinations Update on Adult Immunizations Objectives: Recall the latest recommendations on adult vaccinations Detail the importance of adult vaccinations I m not a kid.. Why are you
Understanding the Purpose and Safety of the Vaccine Schedule: How to Make It Work
Understanding the Purpose and Safety of the Vaccine Schedule: How to Make It Work TRUDY LARSON, MD PROFESSOR AND DEAN, SCHOOL OF COMMUNITY HEALTH SCIENCES UNIVERSITY OF NEVADA, RENO Disclosures This activity
SPECIFIC ANTIINFECTIOUS IMMUNITY. colostral immunity. administration of antibodies VIRULENT VACCINE INACTIVATED VACCINE
INDUCTION OF IMMUNITY AGAINST INFECTION SPECIFIC ANTIINFECTIOUS IMMUNITY active passive S AND VACCINATION infection vaccination colostral immunity administration of antibodies VIRULENT MODIFIED LIVE INACTIVATED
Immunizations for Health Care Workers
Immunizations for Health Care Workers Tanisha Taylor, MD, MPH Senior Medical Director Barnabas Health Corporate Care Tanisha Taylor MD, MPH Senior Medical Director Barnabas Health Corporate Care CDC Immunizations
Vaccinations in MS. Consultant: Accordant, Acorda, Bayer, Biogen, Genentech/Roche, Genzyme/Sanofi, Mylan, Novartis, Serono, Teva
Vaccinations in MS Consultant: Accordant, Acorda, Bayer, Biogen, Genentech/Roche, Genzyme/Sanofi, Mylan, Novartis, Serono, Teva Research: Actelion, Genzyme/Sanofi, Novartis, Opexa 1 Immunobiological product
VACCINATIONS AND INFLAMMATORY BOWEL DISEASE
VACCINATIONS AND INFLAMMATORY BOWEL DISEASE Bob Kizer MD Assistant Professor of Medicine Creighton University School of Medicine CONFLICTS OF INTEREST None 1 AN OPPORTUNITY FOR IMPROVEMENT IBD patients
Immune System. How your body goes to war to keep you well
Immune System How your body goes to war to keep you well WATCH OUT! Millions of bacteria and viruses are everywhere. Many aim to find a host and invade the body. HOW CAN WE DEFEND AGAINST IT? The Bad Guys
Patient Immunization FAQ Sheet
Patient Immunization FAQ Sheet Shingles Vaccine: Q: Who should get the shingles vaccine (Zostavax )? A: Anyone 60 years of age or should get the shingles (herpes zoster) vaccine. There is no maximum age
How does the body defend itself?
Prevention of Infection 2 Immunisation 3 rd BDS B. Martin Major World Causes Of Death COUNTRIES Developing Developed Total x10-6 Population 5400 (80%) 1200 (20%) 6600 CAUSE OF DEATH % % % Infectious diseases
BODY DEFENCES AGAINST DISEASE AND THE ROLE OF VACCINES
BODY DEFENCES AGAINST DISEASE AND THE ROLE OF VACCINES Topic 3 This topic links in with MICROBES (from unit 1) 1. What are the 3 types of microbes? 2. Which microbe do antibiotics destroy? 3. What microbe
Pertussis immunisation for pregnant women
Pertussis immunisation for pregnant women Introduction The routine childhood immunisation programme has been very effective in reducing the overall numbers of cases of pertussis. Before the introduction
Routine Office Visits
Routine Office Visits Routine office visits are scheduled in advance. Since the office computer allows us to book appointments months in advance, you will often be able to make your next appointment as
UPDATE ON IMMUNIZATION GUIDELINES AND PRACTICES
DISCLOSURES UPDATE ON IMMUNIZATION GUIDELINES AND PRACTICES Nothing to disclose Kylie Mueller, Pharm.D., BCPS Clinical Specialist, Infectious Diseases Spartanburg Regional Medical Center LEARNING OBJECTIVES
Immunization Updates, Vaccine Administration, and Safety. Audrey Muñoz, LVN, AAHA Immunization Educator June 20, 2012
Immunization Updates, Vaccine Administration, and Safety Audrey Muñoz, LVN, AAHA Immunization Educator June 20, 2012 Immunization Schedules Use all three schedules: 0-6 years, 7-18 years, and the Catch-Up
Lines of Defense. Immunology, Immune Response, and Immunological Testing. Immunology Terminology
Immunology, Immune Response, and Immunological Testing Lines of Defense If the First and Second lines of defense fail, then the Third line of defense is activated. B and T lymphocytes undergo a selective
Immunization. Immunization procedure called vaccination and the immunizing agent called vaccine (or serum in historical references)
Vaccines BIT 120 Immunization Immunization: a procedure designed to increase concentrations of antibodies and/or effector T-cells which are reactive against infection (or cancer). Immunization procedure
Immunizations June 5, Brenda Ormesher, MD Infectious Disease Peacehealth Medical Group Springfield, OR
Immunizations June 5, 2015 Brenda Ormesher, MD Infectious Disease Peacehealth Medical Group Springfield, OR Disclosures None Goals Understand basic public health impact of immunization Recognize types
Physiology Unit 3. ADAPTIVE IMMUNITY The Specific Immune Response
Physiology Unit 3 ADAPTIVE IMMUNITY The Specific Immune Response In Physiology Today The Adaptive Arm of the Immune System Specific Immune Response Internal defense against a specific pathogen Acquired
Vaccines. Dr. Gary Mumaugh
Vaccines Dr. Gary Mumaugh Vaccines A vaccine is a form of antigen (substance which stimulates an immune response) used to create a barrier of immunity against a specific disease. The term derives from
Immunization:- Immunization is the process whereby a person is made immune or resistant to a specific infectious disease.
Group C Amr Abdel Raouf Definition:- Immunization:- Immunization is the process whereby a person is made immune or resistant to a specific infectious disease. Vaccine: is the administration of antigenic
CHILDHOOD VACCINATION
EPI (3) Age of Child How and Where is it given? CHILDHOOD VACCINATION Nicolette du Plessis Block 10 28/02/2012 10 weeks DTaP-IPV/Hib (2) Diphtheria, Tetanus, Acellular pertussis, Inactivated polio vaccine,
Outline. Animals: Immunity. Defenses Against Disease. Key Concepts:
Animals: Immunity Defenses Against Disease Outline 1. Key concepts 2. Physical barriers: Skin, Mucus and HCL in stomach 3. Non-specific 4. Specific responses Immune System a. Components of Immune system
Vaccines. Vaccines ( continued 1) February 21, 2017 Department of Public Health Sciences
Infectious Disease Epidemiology BMTRY 713 (A. Selassie, DrPH) Lecture 11 Vaccines Past, Present, Future Learning Objectives 1. Identify the various types of vaccines 2. Describe the role of vaccine in
Biomedical Engineering for Global Health. Lecture 9 Vaccine development: from idea to product
Biomedical Engineering for Global Health Lecture 9 Vaccine development: from idea to product Review of lecture 8 Pathogens: Bacteria and Virus Levels of Immunity: Barriers First line of defense Innate
Edmunds: Introduction to Clinical Pharmacology, 8th Edition. 1. Which term refers to a medication containing a weakened or dead antigen?
This is completed: Test Bank for Introduction to Clinical Pharmacology 8th Edition by Edmunds http://testbankair.com/download/test-bank-for-introduction-to-clinical-pharmacology-8thedition-by-edmunds/
3.2 Factors Affecting the Immune System
3.2 Factors Affecting the Immune System Traditional First Peoples Medicines Use of nature For many generation plants, animals and earth substances have been used as healing agents. Examples: Indian Hellebore-skin
D-LAB HEALTH SP 725. Jose Gomez-Marquez
SP 725 Jose Gomez-Marquez 1 Vaccine Preventable Diseases Causes of 2.5 million child deaths out of 10.5 million child deaths globally, 2002 Source: WHO Wkly Epidemiol Rec. (2006) 81:189-196. 2 Rationale
Expanded Programme on Immunization (EPI):
Expanded Programme on Immunization (EPI): Introduction Four to five million annual deaths could be prevented by 2015 through sustained and appropriate immunization efforts, backed by financial support.
Armed Services Blood Program Immunization List
Immunization List NOTICE: The Department of Defense (DoD) assumes no risk for the use of this information by non-dod personnel, blood programs, or individual medical institutions. The use of this information
CyberScan Vaccine Stress Assessment
DEMO CyberScan Vaccine Stress Assessment % imbalance is calculated from 0-100%, with 100% corresponding to increased stress. Level correlates to the aspect of the body affected. Levels 1-3 correspond to
Session 27: Vaccines. Patricia Fitzgerald-Bocarsly May 18, 2009
Session 27: Vaccines Patricia Fitzgerald-Bocarsly May 18, 2009 A brief history of vaccination Immunity: comes from the Latin immunis meaning exempt Concept dates to 430 B.C. when Thucydides, the historian
Practical Applications of Immunology. Chapter 18
Practical Applications of Immunology Chapter 18 I. Vaccines A. Definition A suspension of organisms or fractions of organisms that is used to induce immunity (immunologic memory). The mechanism of memory
CHAPTER ONE: EXECUTIVE SUMMARY. The Global Vaccine Industry CHAPTER TWO: INTRODUCTION TO VACCINES
CHAPTER ONE: EXECUTIVE SUMMARY The Global Vaccine Industry o Scope and Methodology o Overview o Pediatric Preventative Vaccines o The Market o Adult Preventative Vaccines o The Market o Total Market o
CHAPTER 18: Immune System
CHAPTER 18: Immune System 1. What are four characteristics of the specific immune system? a. b. c. d. 2. List the two main types of defense mechanisms and briefly describe features of each. 3. Give examples
Objectives. Immunity. Childhood Immunization Risk of Non-Vaccinated Children 12/22/2015
Childhood Immunization Risk of Non-Vaccinated Children Bertha P. Rojas, Pharm.D. PGY-1 Pharmacy Resident South Miami Hospital Objectives Understand the definition of herd immunity Identify vaccine-preventable
Lesson 3: Immunizations
K-W-L Graphic Organizer K (Know) What do you know about W (Want) What do you want to know about L (Learned) What did you learn about Glossary 1. antibodies: proteins created by the immune system to fight
Pathogens and the immune system
Pathogens and the immune system Veronica Leautaud, Ph.D. vl2@ rice.edu Keck Hall 224 / 232-lab Lecture 8 BIOE 301-Bioengineering and World Health Review of lecture 7 Science Science is the human activity
Vaccinology 101 for Fellows
Vaccinology 101 for Fellows Meg Fisher, MD Medical Director, The Children s Hospital Monmouth Medical Center An affiliate of the Saint Barnabas Health Care System Long Branch, NJ Disclosures I have no
Temperature Intelligence Solutions. Thermostability of Vaccines
Thermostability of Vaccines Why are all vaccines sensitive to heat and some to freezing? Why is thermostability of vaccine important? What can be done to improve the thermostability of vaccines? Goals
The Continued Need for Immunizations in Top Ten Causes of Death in the U.S., 1900 vs Common Questions about Vaccines
The Continued Need for Immunizations in 2016 Stephanie Schauer, Ph.D. Program Manager, Immunization Program April 13, 2016 Ten Great Public Health Achievements United States, 1900-1999 MMWR 1999 Control
The Continued Need for Immunizations in 2016
The Continued Need for Immunizations in 2016 Stephanie Schauer, Ph.D. Program Manager, Immunization Program April 13, 2016 Wisconsin Department of Health Services Ten Great Public Health Achievements United
Glossary of Terms - Vaccinology 101 Nurse TIP Webcast
Glossary of Terms - Vaccinology 101 Nurse TIP Webcast Adaptive Immune response Adaptive immune response or adaptive immunity is the response of antigen-specific lymphocytes to antigen, including the development
A. Children born in 1942 B. Children born in 1982 C. Children born in 2000 D. Children born in 2010
Who do you think received the most immunologic components in vaccines? Development of which vaccine slowed after the invention of antibiotics? A. Children born in 1942 B. Children born in 1982 C. Children
AKE WITH Y KEEP AND T
VACCINATION RECORD Vaccination, the best protection This booklet is an important document. It is the only record of all the vaccines you have received. You will need it all your life, so keep it in a safe
Module 2: Vaccines and drugs: similarities and differences
Module 2: Vaccines and drugs: similarities and differences Vaccine PV Fellowship WHO Collaborating Centre for Advocacy and Training in Pharmacovigilance Accra, Ghana 7 th 18 th September 2015 Learning
Table Of Contents Executive Summary Introduction to Vaccines Pediatric Preventive Vaccines
Table Of Contents Executive Summary THE GLOBAL VACCINES INDUSTRY Scope and Methodology Overview Pediatric Preventative Vaccines THE MARKET Adult Preventative Vaccines THE MARKET TOTAL MARKET ISSUES AND
Inactivated whole-cell (killed antigen) vaccines
Inactivated whole-cell (killed antigen) vaccines Inactivated vaccines are made from microorganisms (viruses, bacteria, other) that have been killed through physical or chemical processes. These killed
Vaccines in Immunocompromised hosts
Vaccines in Immunocompromised hosts Carlos del Rio, MD Emory Center for AIDS Research October 2013 Immunocompromised hosts Number has increased rapidly in the past decades Broad term that encompasses different
1 Principles of Vaccination Immunology and Vaccine-Preventable Diseases... 1 Classification of Vaccines... 4 Selected References...
1 Principles of Vaccination Immunology and Vaccine-Preventable Diseases... 1 Classification of Vaccines... 4 Selected References... 7 2 General Recommendations on Immunization Timing and Spacing of Vaccines...
Overview of Immunizations for People Who Work in Labs
Overview of Immunizations for People Who Work in Labs CLMA/ASCLMS Spring Meeting Little Rock, AR April 5, 2019 Jennifer Dillaha, MD Medical Director, Immunizations Medical Advisor, Health Literacy Arkansas
Immunizations for Children and Teens with Suppressed Immune Systems
Immunizations for Children and Teens with Suppressed Immune Systems Your child is starting treatment that will suppress the immune system. This will affect how your child s body responds to routine immunizations
Update on Immunizations and the Shingles Vaccine
Update on Immunizations and the Shingles Vaccine Conflict of Interest Disclosure I have no conflicts of interest to disclose. Sarah Scoular, PharmD., BCPS Annual Meeting 2018 Objectives 1. Describe the
Therapeutic Cancer Vaccines
Therapeutic Cancer Vaccines Goal for all therapeutic cancer vaccines: To enhance the natural immune response so that it becomes an effective therapy Approaches being investigated in clinical studies: Whole
Adolescent vaccination strategies
Adolescent vaccination strategies Gregory Hussey Vaccines for Africa Initiative Institute of Infectious Diseases & Molecular Medicine University of Cape Town www.vacfa.uct.ac.za gregory.hussey@uct.ac.za
Twinrix Combined Hep A and B
Twinrix Combined Hep A and B Cost $70.00 per injection. 3 required Standard course: 0, 1, 6 months Blood test recommended after course complete site of injection Vaqta Hepatitis A Vaccine Adults: cost
Chapter 21: Innate and Adaptive Body Defenses
Chapter 21: Innate and Adaptive Body Defenses I. 2 main types of body defenses A. Innate (nonspecific) defense: not to a specific microorganism or substance B. Adaptive (specific) defense: immunity to
Benefit Interpretation
Benefit Interpretation Subject: Part B vs. Part D Vaccines Issue Number: BI-039 Applies to: Medicare Advantage Effective Date: May 1, 2017 Attachments: Part B Vaccines Diagnosis Code Limits Table of Contents
Vaccination and Immunity
Vaccination and Immunity Eric A. Utt, PhD Director, Worldwide Science Policy Pfizer Inc California Immunization Coalition Summit 2012 Completing the Circle: Ensuring Adult & Adolescent Vaccination for
What s in Animal Vaccines? Accidental Injections and Needle Sticks: How Harmful Are they to People? Chris Chase
What s in Animal Vaccines? Accidental Injections and Needle Sticks: How Harmful Are they to People? Chris Chase Credits Texas A & M AAFP Overview Accidental Injections Vaccine components Needlesticks Contact
Monitoring Vaccines Introduction. Pia Caduff-Janosa MD May 2013
Monitoring Vaccines Introduction Pia Caduff-Janosa MD May 2013 Outline Historical background Are vaccines different from other medicinal products? Different vaccines different potential safety issues Immunization
Measles, Mumps and Rubella. Ch 10, 11 & 12
Measles, Mumps and Rubella Ch 10, 11 & 12 Measles Highly contagious viral illness First described in 7th century Near universal infection of childhood in prevaccination era Remains the leading cause of
Vaccine. Design and Manufacturing. Liting Bi. https://en.wikipedia.org/wiki/vaccine
Vaccine Design and Manufacturing Liting Bi https://en.wikipedia.org/wiki/vaccine 1 Outline Vaccine Intro. 4 Vaccine Types 2 Manufacturing Methods 2 Tests & Applications Take-home messages 2 https://www.youtube.com/watch?v=t_me5ef0ne4
Stainless-steel vs Single-use: The Vaccines Perspective
Stainless-steel vs Single-use: The Vaccines Perspective CMO-Biomanufacturer Panel Tue 21 April, Noon-1:30pm, Exhibit Hall Daniel C.Vellom, PhD Sr. Director Global Technology Innovation 2015 INTERPHEX 1
General Recommendations on Immunization
General Recommendations on Immunization This chapter discusses issues that are commonly encountered in vaccination practice. A more thorough discussion of issues common to more than one vaccine can be
4) What causes lymph to move? Skeletal muscle contraction; smooth muscle contraction, breathing (like blood moves through veins)
NPHS Anatomy & Physiology UNIT 10 REVIEW GUIDE Lymphatic System 1) List the three functions of the lymphatic system. transports excess fluid to the bloodstream absorbs fats helps defend the body against
Economics of Vaccine Development A Vaccine Manufacturer s Perspective
Economics of Vaccine Development A Vaccine Manufacturer s Perspective Gerald Voss The Value of Vaccines 2 29 diseases are currently preventable by vaccination Global public health Cervical cancer 1 Diphtheria
Study Guide 23, 24 & 47
Study Guide 23, 24 & 47 STUDY GUIDE SECTION 23-3 Bacteria and Humans Name Period Date 1. One bacterial disease that is transmitted by contaminated drinking water is a. Lyme disease b. gonorrhea c. tuberculosis
Vaccine Design: A Statisticans Overview
GoBack : A Statisticans Overview. Surajit Ray sray@samsi.info Surajit Ray Samsi PostDoc Seminar: Nov 2: 2004 - slide #1 The Chinese are credited with making the observation that deliberately infecting
All animals have innate immunity, a defense active immediately upon infection Vertebrates also have adaptive immunity
1 2 3 4 5 6 7 8 9 The Immune System All animals have innate immunity, a defense active immediately upon infection Vertebrates also have adaptive immunity Figure 43.2 In innate immunity, recognition and
Preventative Vaccines. Vaccines for Special Populations. Vaccinations for Adults: An Update. Vaccines Generally Available in the U.S.
Vaccinations for Adults: An Update Preventative Vaccines Need to be extremely safe Even greater issue as disease prevalence wanes or uncommon diseases targeted Lisa G. Winston, MD University of California,
Guideline for the immunization of HIV infected persons in Sri Lanka
DOI: http://doi.org/10.4038/joshhm.v3i0.64 Guideline for the immunization of HIV infected persons in Sri Lanka Dr. M. K. Darshanie Mallikarachchi, Consultant Venereologist, Provincial General Hospital
Viral vaccines. Lec. 3 أ.د.فائزة عبد هللا مخلص
Lec. 3 أ.د.فائزة عبد هللا مخلص Viral vaccines 0bjectives 1-Define active immunity. 2-Describe the methods used for the preparation of attenuated live & killed virus vaccines. 3- Comparison of Characteristics
Vaccinations for Adults
Case: Vaccinations for Adults Lisa Winston, MD University of California, San Francisco San Francisco General Hospital A 30-year old healthy woman comes for a routine visit. She is recently married and
Recommended Vaccinations for Patients with Chronic Lung Disease RORY JOHNSON, PHARM.D., AE C ASSISTANT PROFESSOR UNIVERSITY OF MONTANA
Recommended Vaccinations for Patients with Chronic Lung Disease RORY JOHNSON, PHARM.D., AE C ASSISTANT PROFESSOR UNIVERSITY OF MONTANA Disclosures Nothing to Disclose Learning Objectives At the conclusion
Vaccinations in lupus. Juan Schmukler, MD
Vaccinations in lupus Juan Schmukler, MD Juan_Schmukler@rush.edu Talk outline How vaccines work and why they are important Types of vaccines Vaccines that people with lupus can (and should) get A (mega
Vaccines. Magdalena Sobieszczyk, MD, MPH Division of Infectious Diseases Columbia University. Outline
Vaccines Magdalena Sobieszczyk, MD, MPH Division of Infectious Diseases Columbia University Outline Public health impact of vaccines Historical perspective Active vs. Passive Immunization Immune system