Being the partner of choice

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1 Being the partner of choice IDS Media conference, 13 March 2013 Frank Hemm, Executive Vice President Sales EMEA/LATAM Dr. Sandro Matter, Executive Vice President BU Prosthetics Product availability The availability and indications of the products mentioned and/or illustrated in this presentation may vary according to country. Straumann a global leader in replacement, restorative and regenerative dentistry Implant solutions Restorative solutions Regenerative solutions 2 1

New introductions from Straumann NNC Loxim Emdogain 015 Sterile Healing TiBrush

0 Patient App 3 Standard Plus Narrow Neck CrossFit (NNC) New-generation small-diameter

philosophy SLActive surface Roxolid material Consistent Emergence Profiles CrossFit at

fastest healing surface technology CrossFit, our reliable, intuitive connection Soft

2 New introductions from Straumann NNC Loxim Emdogain 015 Sterile Healing TiBrush Indication-Based Product Selection Guide codiagnostix 9.0 Patient App 3 Standard Plus Narrow Neck CrossFit (NNC) New-generation small-diameter soft tissue-level implant for limited space and narrow bone ridges Soft Tissue Level philosophy SLActive surface Roxolid material Consistent Emergence Profiles CrossFit at soft tissue level Bone Control Design Roxolid, our strongest material SLActive, our fastest healing surface technology CrossFit, our reliable, intuitive connection Soft tissue level design: onestage surgery Indications include: front singletooth gaps or multiple-tooth replacement (bridges and fixed/removable overdentures) 4 2

support healing All implant closure screws and healing abutments delivered in sterile packaging

3 Loxim implant transfer instrument Detaches faster and easier from the implant after placement Very high precision Introduced on our premium Roxolid SLActive implants 5 Sterile packaging to support healing All implant closure screws and healing abutments delivered in sterile packaging to meet increased hygiene requirements in many markets Introduction May 2013 No price addition 6 3

Straumann TiBrush Simple, effective instrument for mechanical debridement of implant surfaces affected by peri-implantitis 1 Designed to prolong life of compromised

Schwarz et al.: Rotating titanium brush for plaque removal from rough titanium surfaces an in-vitro study, accepted for publication, Clin. Oral Impl. Res. 2.D.

:10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients.

4 Straumann TiBrush Simple, effective instrument for mechanical debridement of implant surfaces affected by peri-implantitis 1 Designed to prolong life of compromised implants Straumann implants have shown very low prevalence of peri-implantitis over 10 years 2 but the general need for maintenance is expected to rise 7 1.F. Schwarz et al.: Rotating titanium brush for plaque removal from rough titanium surfaces an in-vitro study, accepted for publication, Clin. Oral Impl. Res. 2.D. Buser et al.:10-year survival and success rates of 511 titanium implants with a sandblasted and acid-etched surface: a retrospective study in 303 partially edentulous patients. Clin Implant Dent Relat Res 2012;14(6): Emdogain 015 an ideal, cost-effective solution for smaller needs in daily practice New size and options (combination with various bone graft materials 1 ) >10 years in-market experience >1.5 million patients treated >400 clinical publications 8 1 Cleared in US and allowed in Europe 8 4

Efficiency gains: fewer patient consultations; no scan template required Additional surgical

5 codiagnostix 9.0 Launch at the IDS by Dental Wings New guided surgery software with additional functionality Efficiency gains: fewer patient consultations; no scan template required Additional surgical template production using precision 3D printing technology 9 Straumann Indication-Based Product Selection Guide Helps to select the most suitable Straumann implant and prosthetic components 10 5

Straumann Patient Education App A convenient modern way to communicate the

Treatment option videos Interactive drawing tools E-mail and print options

Paradigm shift to smaller implants Preserve buccal and interproximal bone and

Shorten treatment 3,4 Reduce cost 3 Reduce discomfort 3 Minimally invasive

: Clin Oral Impl Res, 20 (Suppl), 2009 2. Freiberger P, Al-Nawas B.

6 Straumann Patient Education App A convenient modern way to communicate the benefits of dental implants and treatment options/procedures to patients. Treatment option videos Interactive drawing tools and print options for sharing Editing/customizing options Archive for custom presentations 11 Paradigm shift to smaller implants Preserve buccal and interproximal bone and vital structures 1 Avoid bone augmentation 2,3 Limit patient morbidity 3 Shorten treatment 3,4 Reduce cost 3 Reduce discomfort 3 Minimally invasive Reduced complexity Increased patient acceptance Teughels et al.: Clin Oral Impl Res, 20 (Suppl), Freiberger P, Al-Nawas B. Non-interventional study on success and survival of TiZr implants. EAO 2012, Abs. # Fuggazzotto: Implications of Roxolid implants in clinical practice, Implant realities vo. 1, R. Jung, key success factors for implant treatment, EAO Copenhagen

Paradigm shift to smaller implants Straumann technology Future trend Roxolid + SLActive Smaller implants in all cases it seems reasonable to assume that use of a narrower

1mm wide titanium implant would usually be placed, it appears reasonable to utilize a 3.3mm wide titanium zirconium implant body instead. Dr Paul A.

1, 2012 Savings that smaller implants may offer German example: reimbursement scheme for implantation 1 Year Implant(s) without GBR ( ) 1988 2012 1988 2012 1988 2012 1 2 3

7 Paradigm shift to smaller implants Straumann technology Future trend Roxolid + SLActive Smaller implants in all cases it seems reasonable to assume that use of a narrower diameter implant reduction equal to one implant size from the conventionally accepted implant in a given situation is warranted. For example, if a 4.1mm wide titanium implant would usually be placed, it appears reasonable to utilize a 3.3mm wide titanium zirconium implant body instead. Dr Paul A. Fuggazzotto, DDS, Periodontist, Milton, Massachusetts Fuggazzotto: Implications of Roxolid implants in clinical practice, Implant realities vo. 1, 2012 Savings that smaller implants may offer German example: reimbursement scheme for implantation 1 Year Implant(s) without GBR ( ) with GBR ( ) Average savings for patient of approximately 600 if GBR is avoided Reimbursement Increased for simple implantation Reduced for implantation with GBR 14 1 GOÄ change in

Stretching the bounds of clinical excellence 7% of revenues invested in R&D (industry benchmark 1 ) 16 clinical studies running 2 7 clinical studies completed in 2012 2 31 new studies planned for

$8%) prevalence of peri-implantitis 1 No implant fracture noted 1 No screw or abutment fractures 2 1 Buser D et al: 10-Year Survival and Success Rates of 511 Titanium Implants with a Sandblasted and$

8 Stretching the bounds of clinical excellence 7% of revenues invested in R&D (industry benchmark 1 ) 16 clinical studies running 2 7 clinical studies completed in new studies planned for year data for SLA implants 5-year data for SLActive implants 3-year data for Roxolid implants 10-year data for Emdogain 15 1 Based on available data 2 as of 31 December 2012 Strong 10-year clinical data on Straumann implants 643 Straumann SLA tissue level implants tracked for 10 years in two studies 1,2 Survival rate of 98.8% and success rate of 97.0% 1 Very low (1.8%) prevalence of peri-implantitis 1 No implant fracture noted 1 No screw or abutment fractures 2 1 Buser D et al: 10-Year Survival and Success Rates of 511 Titanium Implants with a Sandblasted and Acid-Etched Surface: A Retrospective Study in 303 Partially Edentulous Patients. Clin. Impl. Dent. Relat. Res. 14, 6, Fischer K, Stenberg T: Prospective 10-year cohort study based on a randomized, controlled trial on implant-supported full-arch maxillary prostheses. Part II: Prosthetic outcomes and maintenance. (132 implants on 23 screw-retained full-arch prostheses in 23 patients) Clin Impl. Dent Relat Res 2011;[Epub]. 16 8

Straumann prevails in Swiss and German courts X Illegal promotion There are no generic, bioequivalent dental implants; labelling as such is illegal Implant imitators have little, if any, supporting

9 Straumann prevails in Swiss and German courts X Illegal promotion There are no generic, bioequivalent dental implants; labelling as such is illegal Implant imitators have little, if any, supporting research documentation / biological rationale Dental Ratio Systems banned from claiming Oktagon implant components are compatible with Straumann Medentis Medical banned from claiming ICX-templant is hydrophilic 17 Straumann Digital Solutions Dr Sandro Matter, Executive Vice President Business Unit Prosthetics Implant solutions Restorative solutions Regenerative solutions 18 9

Implants complemented by a wide range of prosthetic solutions 19 backed by strong

$8%) prevalence of peri-implantitis 1 No implant fracture noted 1 No screw or abutment$ $fractures 2 1 Buser D et al: 10-Year Survival and Success Rates of 511 Titanium Implants$ Edentulous Patients. Clin. Impl. Dent. Relat. Res.

Edentulous Patients. Clin. Impl. Dent. Relat. Res.

randomized, controlled trial on implant-supported full-arch maxillary prostheses.

10 Implants complemented by a wide range of prosthetic solutions 19 backed by strong 10-year clinical data 643 Straumann SLA tissue level implants tracked for 10 years in two studies 1,2 Survival rate of 98.8% and success rate of 97.0% 1 Very low (1.8%) prevalence of peri-implantitis 1 No implant fracture noted 1 No screw or abutment fractures 2 1 Buser D et al: 10-Year Survival and Success Rates of 511 Titanium Implants with a Sandblasted and Acid-Etched Surface: A Retrospective Study in 303 Partially Edentulous Patients. Clin. Impl. Dent. Relat. Res. 14, 6, Fischer K, Stenberg T: Prospective 10-year cohort study based on a randomized, controlled trial on implant-supported full-arch maxillary prostheses. Part II: Prosthetic outcomes and maintenance. (132 implants on 23 screw-retained full-arch prostheses in 23 patients) Clin Impl. Dent Relat Res 2011;[Epub]

contour crown CARES Coping 3M ESPE IPS e.

max is a registered trademark of Ivoclar

11 Customized prosthetics in a broad range of high performance materials CARES Full contour crown CARES Coping 3M ESPE IPS e.max polycon zerion IPS e.max HT Lava Ultimate zerion ae CAD Restorative CAD coron CARES Abutment, Zirconium dioxide 1 CARES Abutment, Titanium 21 1 Not available for the Soft Tissue Level WN Platform 3M, ESPE and Lava are trademarks of 3M or 3M Deutschland GmbH. Used under license in Canada. IPS e.max is a registered trademark of Ivoclar Vivadent AG, Liechtenstein. New introductions from Straumann CARES X-Stream CARES Variobase abutment Broader range of CARES screw-retained bars & bridges Full-contour zirconia zerion HT CARES Visual 8.0 CARES Scan & Shape 48h zerion delivery 1 SFI Anchor 22 1 In most European countries 11

CARES X-Stream Complete implant-borne restoration

restoration solution for Straumann implants High

workflow One scan one design one delivery Time

Variobase abutment Hybrid abutment with zerion

to individual oral situation Four shades Guided

12 CARES X-Stream Complete implant-borne restoration in one step Full single-tooth prosthetic restoration solution for Straumann implants High quality and profitability through validated workflow One scan one design one delivery Time (up to 3 days) and cost savings 23 CARES Variobase abutment Hybrid abutment with zerion coping Designed for efficiency Highly adaptable to individual oral situation Four shades Guided placement of coping Ideal force distribution Original Straumann connection 24 12

CARES full contour zerion HT 1 Translucent ZiO 2 ceramic in 4 shades Easy

units) Durable, predictable 25 1 High Translucency CARES screw-retained

designs for Straumann Tissue Level Implant platform Milled in one-piece

13 CARES full contour zerion HT 1 Translucent ZiO 2 ceramic in 4 shades Easy and efficient handling Full-contour crown and bridge restorations (up to 3 units) Durable, predictable 25 1 High Translucency CARES screw-retained bars and bridges Now for Straumann Bone Level Implants Four additional bar designs for Straumann Tissue Level Implant platform Milled in one-piece with smooth machined surface and customizable bone level emergence profile 26 13

SFI Anchor Flexible, secure, durable implant anchor for edentulous solutions: Compensates implant divergences up to 60 Easy maintenance, high patient comfort Exclusively from

14 SFI Anchor Flexible, secure, durable implant anchor for edentulous solutions: Compensates implant divergences up to 60 Easy maintenance, high patient comfort Exclusively from Straumann 27 High precision design and production Pre-set parameters and algorithms Consistant quality, high precision and high performance materials with centralized milling 28 14

15 Excellent fit e.g. CARES X-Stream prosthetic elements No visible marginal gap Homogeneous cement gap 29 Precise connection, optimal force distribution Patented 1 engaging mechanism Very small rotational play Defined, controllable bonding gap Even load distribution 30 1 Patent pending 15

16 Two ways to Straumann CARES abutments Straumann CARES System 8.0 Straumann CARES Scan & Shape 31 Straumann CARES System 8.0 Open CADCAM system integrated into DWOS platform Validated workflow with Straumann support New design functionality and flexibility Easier to use Added efficiency Faster delivery DWOS inside New software free for existing customers with up-to-date licenses; available to new customers for purchase 32 16

Optimized Straumann CARES digital workflow Multiple

materials & applications Manufacturing options Surgical

straumann CARES desktop Validated workflow Straumann

0 CARES (Variobase) Abutments, CARES SRBB, CARES

Center Scan mastermodel Straumann CARES Scan CS2

abutments, bars Open STL to external milling center of

collaborations with 3M ESPE and Innovation MediTech

Dentists can send digital impressions directly to labs

0 Labs design and order CARES prosthetics for Straumann

17 Optimized Straumann CARES digital workflow Multiple data sources Straumann CARES Visual Design Variety of materials & applications Manufacturing options Surgical planning Straumann CARES Digital impression taking my.straumann CARES desktop Validated workflow Straumann CARES Visual 8.0 CARES (Variobase) Abutments, CARES SRBB, CARES Elements, Straumann CARES X-Stream Straumann Milling Center Scan mastermodel Straumann CARES Scan CS2 External workflow Straumann CARES Visual 8.0 Crowns & bridges, abutments, bars Open STL to external milling center of user s choice 33 Complete digital workflow through collaborations with 3M ESPE and Innovation MediTech Trusted Connection with 3M True Definition Scanner Dentists can send digital impressions directly to labs using Straumann CARES 8.0 Labs design and order CARES prosthetics for Straumann implant-/tooth-borne restorations With Dental Wings Virtual Model Builder software, labs can order corresponding highprecision model from Innovation MediTech 34 17

18 Straumann CARES Scan & Shape A new service for customers who do not have the requisite scanning capabilities Convenient ordering Premium CARES abutments Original connection High surface quality Customized emergence profile Multiple material options Straumann guarantee and reliability 35 How it works Customer sends model or wax-up to Straumann We scan it and shape the custom abutment Customer approves design online Abutment milled and delivered within 4 days 36 18

19 See the connectivity 37 Please visit us in Hall 4.2, stand G80/K

We invite you to the DWOS Lunch & Learn event @ IDS 15 March

20 We invite you to the DWOS Lunch & Learn IDS 15 March 2013, 12.00h, Kristallsaal, Messe Köln (lunch will be served) 39 20

Being the partner of choice

Being the partner of choice Investor Breakfast IDS Cologne, 24 March 2011 Straumann: a global leader in replacement, restorative and regenerative dentistry Dental implant systems Regeneratives 2 What are