2.5 mg dental insert [chlorhexidine digluconate] Uniquely different...
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1 2.5 mg dental insert [chlorhexidine digluconate] Uniquely different...
2 Risks associated with Periodontal disease 1 Diabetes Diabetic patients are more likely to develop periodontal disease, which in turn can increase blood sugar and diabetic complications. Heart Disease Several studies have shown that periodontal disease is associated with heart disease. Respiratory Disease Research has found that bacteria that grows in the oral cavity can be aspirated into the lungs to cause respiratory diseases such as pneumonia, especially in people with periodontal disease. Cancer Researchers found that men with gum disease were 49% more likely to develop kidney cancer, 54% more likely to develop pancreatic cancer, and 30% more likely to develop blood cancers. Premature Birth Risk The NHS offers free dental checks to women who are pregnant. One reason for this is that unborn babies are at an increased risk of premature birth if the mother is suffering from periodontal disease. Osteoporosis Studies suggest that osteoporosis may lead to tooth loss because the density of the bone that supports the teeth may be decreased, which means the teeth no longer have a solid foundation. Stroke Additional studies have pointed to a relationship between periodontal disease and stroke.
3 Chronic Periodontal disease is on the increase 1 Chronic Gum Disease is up by 50% 2 Gum disease is the main cause of tooth loss 3 Chronic Periodontal disease is on the increase Recent data shows that periodontal disease is the main cause of tooth loss amongst adults % patients with periodontal pockets 6mm Reason for tooth loss 10% 9% 8% 7% 6% 5% 4% 3% 2% 1% 0% Years 13% 8% 6% 73% Periodontal disease Endontic Root caries Other
4 2.5 mg dental insert [chlorhexidine digluconate] Uniquely different...
5 Bacterial Resistance - ticking time bomb? In a recent statement from the World Health Organisation on World Health Day 2011, it was highlighted that micro-organisms are becoming resistant to antibiotics, so their widespread use should be managed positively: In the absence of urgent corrective and protective actions, the world is heading towards a post-antibiotic era, in which many common infections will no longer have a cure and, once again, kill unabated. 4 Antibiotics which have a profound effect against systemic infections should be used prudently and not for infections that other anti-microbial agents have been shown to be effective against and have a lower propensity to induce resistance. Clinical microbiology studies with chlorhexidine mouthrinse have demonstrated the efficacy of chlorhexidine in reducing the numbers of periodontopathic bacteria, with a minimal risk of developing resistance. These studies, demonstrating the use of chlorhexidine for 6 months and up to 2 years, did not result in overgrowth of pathogenic bacteria or changes in the antimicrobial susceptibility of the oral flora. There is no concern about the development of chlorhexidine resistance following PerioChip administration. 5 13% PerioChip is CONFIDENCE
6 Why use PerioChip? PerioChip Chlorhexidine Release Profile in Periodontal Pockets Kills 99% of Periopathogenic Bacteria for up to 10 days 6 Contains 36% chlorhexidine digluconate High concentration of CHX in the pocket within 2 hours 6 No evidence of systemic absorption No chance of bacterial resistance Can be used on all pockets equal to or greater than 5 mm Minimum Inhibitory Concentration level maintained for up to 10 days 6 Can be used by Dentists, Therapists and Hygienists Does not require a prescription to use Suppresses bacterial flora for up to 11 weeks No Antibiotics Chlorhexidine Concentration (mcg/ml) MIC mcg/ml Days
7 Why PerioChip? EFFECTIVE CONFIDENCE EASY WORKS
8 1 st application 2 nd application 3 rd application 9 month review tooth with periodontitis pocket improvement pocket improvement pocket improvement day 1 day 90 day 180 day 270 PerioChip WORKS Pocket 8 mm Pocket 6 mm Pocket 5 mm Pocket 2-4 mm
9 Significantly more effective compared to RSD * alone Significant improvement in PD compared to RSD alone 7 PerioChip is 5 x more Effective at reducing Pocket Depth (PD) compared to Root Surface Debridement (RSD) alone 7 Pockets 7 mm at Baseline PerioChip periodontal long term treatment PerioChip is an Effective Long Term Treatment 8 Pockets reduction over 24 months 100 PerioChip & RSD RSD alone 80 73% Cumalative Percentage % 8.2% Visit Month Improvement No change Worsening Pocket Depth: 2-4 mm 5-6 mm 7-8 mm * RSD - Root Surface Debridement 58.9 % of periodontal pockets were reduced to < 5 mm % of periodontal pockets between mm were reduced by 2 mm or more over 24 months 8
10 Simple FOR BEST RESULTS Place PerioChip every 3 months Use as an adjunctive therapy with RSD for periodontal pockets 5 mm Use repeatedly as part of your periodontal treatment programme Remove the foil packet from the box and peel back the foil to reveal one PerioChip (chlorhexidine digluconate 2.5mg). Using suitable forceps, grasp the PerioChip at the flat end. Insert the PerioChip, curved end first, into the periodontal pocket Press the PerioChip apically to the base of the pocket. After proper insertion, the PerioChip should rest subgingivally at the base of the pocket
11 Simple. Minimal interference with daily routine Easy to insert by trained dental and periodontal staff after routine root surface debridement Can be used in regular periodontal and dental care maintenance PerioChip is SIMPLE
12 TESTIMONIALS What professionals say about PerioChip
13 What the professionals say Dr Amit Patel Specialist in Periodontics and Implants Dr Poonum Winayak Principal Dental Surgeon at Osterley Dental Practice and Ealing Dental Care, has been using PerioChip for over 10 years Fiona Moffat Dental Therapist at Grassington Dental Care, has been using PerioChip for over a year There s a lot of undiagnosed periodontal disease within the population. If we diagnose and treat this quicker it will mean less invasive treatment in the future for our patients and they will be able to keep their teeth longer. PerioChip is really easy to use especially when used correctly in pockets of 5mm and above. I have found that the PerioChip is well accepted by patients and I have seen good results in the reduction of periodontal pocketing. I have encouraged all the associates here to use PerioChip because I find it so very effective and the results are amazing. My patients are always happy because they would rather undergo successful treatment to save a tooth than have it extracted. PerioChip assists me to deliver first class treatment and I would recommend it to other practitioners because it is a very good product. I first tried PerioChip as a one-off, but quickly found that we were getting better results with it as an adjunct to scaling and root planing compared to antibiotics. I would definitely say that I felt I was getting better results from PerioChip than other alternatives.
14 PerioChip PerioChip as part of a periodontal treatment programme PerioChip Abbreviated Prescribing Information References: Include PerioChip as part of your periodontal treatment programme for all pockets 5 mm: Maintains a high concentration of chlorhexidine digluconate in the pocket for up to 10 days Suitable for long term use No bacterial resistance Significantly greater pocket depth reduction compared to RSD alone 1. American Academy of Periodontology Gum Disease Information. [ONLINE] Available at: [Accessed 01 May 15]. 2. White D, et al. The 2009 Adult Dental Health Survey, disease and related disorders, a report from the Adult Dental Health Survey. 2009, March, pages Ravald N, Starkhammar Johansson C. et al. Tooth loss in periodontally treated patients. A long-term study of periodontal disease and root caries. J Clin Periodontol 2012;39: World Health Day 2011, News Release, 6th April 2011, Geneva PerioChip Summary of Product Characteristics (SmPC). 6. Soskolne W.A et al. An in vivo study of the Chlorhexidine release profile of the PerioChip in the gingival crevicular fluid, plasma and urine. J Clin Perio. 1998;25: Soskolne W.A et al. Sustained local delivery of Chlorhexidine in the treatment of Periodontitis: A multi centre study. J Perio1997;68: Soskolne W.A et al. Probing depth changes following 2 years of periodontal maintenance therapy including adjunctive controlled-release of Chlorhexidine. J Perio 2003;74: PerioChip 2.5 mg Dental Insert [chlorhexidine digluconate] For full prescribing information, including side effects, precautions and contraindications, see Summary of Product Characteristics (SmPC). Presentation: Dental insert: bullet shaped orange brown containing chlorhexidine digluconate 2.5 mg. Indications: PerioChip is an adjunctive antimicrobial treatment for moderate to severe chronic periodontal disease in adults with pocketing, combined with Root Surface Debridement (RSD). Not indicated in children and adolescents. Dosage and Administration: One PerioChip is inserted into a periodontal pocket with a probing pocket depth of 5 mm. Retreatment with PerioChip following mechanical plaque removal at 3 month intervals may provide additional benefit if pocket depth remains 5 mm. For details see SmPC. Removal is unnecessary as PerioChip biodegrades. Contraindications: Hypersensitivity to Chlorhexidine digluconate or excipients. Precautions: Allergic reactions have occurred but are rare. Interactions: Avoid nystatin: antagonistic of chlorhexidine. Chlorhexidine is incompatible with anionic agents present in some toothpastes and with dietary sucrose, but there is no significant impact on the efficacy of PerioChip. Undesirable effects: During the first few days after insertion, transient pain or discomfort of gums or teeth; redness and/or swelling of the gums. Overdose: Not reported. Pregnancy/ Lactation: Controlled studies in pregnant women have not been conducted, so weigh expected benefits against possible foetal risks: caution in nursing mothers (see SmPC). NHS list price: Legal category: P, Product Licence Number: PL 14017/0035 MA holder: Full prescribing information is available on request from Dexcel Pharma Ltd, 7 Sopwith Way, Drayton Fields Industrial Estate, Daventry, Northants, NN11 8PB. Adverse events should be reported. Reporting forms and information can be found at Adverse events should also be reported to: Dexcel Pharma Ltd on Freephone: DPD/16/0012 Date of preparation February 2016
15 2.5 mg dental insert [chlorhexidine digluconate] Uniquely different...
16 2.5 mg dental insert [chlorhexidine digluconate] Uniquely different...
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