What s New in Alopecia Areata
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1 AN UPDATE ON THE LAST 12 MONTHS What s New in Alopecia Areata PhD FRCPC Dermatologist Assistant Professor, University of Toronto
2 Getting information out to Physicians
3 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
4 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
5 Can cholesterol medications help alopecia areata?
6 STATINS Lower cholesterol Reduce inflammation
7 STUDY Highlights Treatment of alopecia areata with simvastin/ezetimibe. Journal of the American Academy of Dermatology patients Treated with simvastatin and ezetimibe 24 weeks 75 % improved hair Stopping the drug lead to hair loss
8 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
9 What is Platelet rich plasma?
10
11 Journal of the American Academy of Dermatology Case Reports 2015
12 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
13 STUDY Highlights Reduced incidence of skin cancer in patients with alopecia areata. Cancer Epidemiology patients with AA 4242 patients without AA 37 % reduced risk of skin cancer in individuals with alopecia areata
14 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
15 STUDY Highlights Intralesional triamcinolone acetonide vs topical betamethasone valerate in the management of localized alopecia areata. J Coll Physicians Surg Pak patients 113 receiving steroid injections 113 received topical steroids Better hair growth in those receiving steroid injections
16 Five new studies to discuss Can cholesterol medications help alopecia areata? What is platelet rich plasma (PRP) and can it help? Does having alopecia areata reduce the risk of getting skin cancer? Are steroid injections better than topical steroids? Tofacitinib and Ruxolitinib: Do these new drugs help alopecia areata?
17 The JAK KINASES J Invest Dermatol Dec;134(12): Craiglow BG1, King BA1.
18 STUDY Highlights Harris JE. Rapid skin repigmentation on oral ruxolitinib in a Patient with coexistent vitiligo and alopecia areata (AA). Journal of the American Academy of Dermatology Feb year old male Vitiligo and alopecia areata Hair regrowth starting at 4 weeks and signficant by three months
19 STUDY Highlights Craiglow BG et al. Topical ruxolitinib for the treatment of alopecia areata universalis. JAMA Dermatology April 2016
20 AN UPDATE ON THE LAST 12 MONTHS What s New in Alopecia Areata PhD FRCPC Dermatologist Assistant Professor, University of Toronto
Andrei Metelitsa, MD, FRCPC, FAAD Co-Director, Institute for Skin Advancement Clinical Associate Professor, Dermatology University of Calgary, Canada
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