2nd block:

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1 Program of Study : General Medicine Course : Internal Medicine III, A1 Abbreviation : IN3/VA012 Schedule : 1st block: nd block: Course Distribution : 5 year, 9 and 10 semester, Number of Credits : 10 Course Form : ectures (10), seminars (50), exercises (60) Seminars (S) and lectures (): eading teacher: Teachers : Prof. MUDr. J. Zadražil, CSc. Prof. MUDr. V. Ščudla,CSc. Prof. MUDr. K. Indrák, DrSc. Prof. MUDr. H. Vaverková, CSc. Prof. MUDr. P. Horák, CSc. Prof. MUDr. T. Papajík, CSc. Prof. MUDr. E. Faber, CSc. Doc. MUDr. J. Bačovský, CSc Doc. MUDr. Z. Fryšák, CSc. Doc. MUDr. D. Karásek, Ph.D Doc. MUDr. K. Krejčí, Ph.D Doc. MUDr. V. Procházka, Ph.D Doc. MUDr. P. Rohoň, Ph.D Doc. MUDr. T. Szotkowski, Ph.D Prim. MUDr. D. Galuszková, Ph.D MUDr. A. Smržová, Ph.D MUDr. A. Hluší, Ph.D MUDr.. Raida, Ph.D MUDr. R. Metelka, Ph.D MUDr. M. Halenka, Ph.D MUDr. J. Vymětal, Ph.D MUDr.. Cibičková, Ph.D. MUDr. K. Žamboch, Ph.D. MUDr. J. Schovánek, Ph.D. MUDr. M. Skácelová, Ph.D. MUDr. Z. Kosatíková MUDr. M. Hrubý MUDr. J. Orság MUDr. O. Krystyník MUDr. D. Číhalíková MUDr. V. Klementa MUDr. M. Palová

2 Study: Block 1st Blocks date: Start of teaching block take place in the lecture room of the 3rd Department of Internal Medicine - Dept. 39 A (first floor) ,45 h. ectures () and seminars (, ) take place in the lecture room of the 3rd Department of Internal Medicine ( ) or Department of Haematooncology ( ) Block Day Subject No. of ess ( ) Start of teaching block Teacher (MUDr. J. Schovánek,PhD.) ( ) Acute leukaemias, myelodysplastic syndrome Doc. P. Rohoň,Ph.D. (Doc.T.Szotkowski,PhD.) Hereditary and acquired haemolytic anaemias, haemoglobinopathies Chronic myeloid leukaemia, Phnegative myeloproliferative disorders Prof. K. Indrák,DrSc. (MUDr.. Raida,Ph.D) Prof. E. Faber,CSc. (Prof. K. Indrák,DrSc.) Diagnostics, classification and treatment of bleeding disorders Thrombophilic disorders MUDr. A. Hluší,Ph.D (MUDr. M. Palová) MUDr. M. Palová (MUDr. A. Hluší,Ph.D) Malignant lymphomas Polycythaemia vera and other polycythemias, differential diagnosis and therapy Chronic lymphoprolipherative disorders Diagnosis and treatment of monoclonal gamapathies Doc. V. Procházka,Ph.D. (Prof. T. Papajík,CSc.) Prof. K. Indrák,DrSc. (Prof. E. Faber,CSc.) Doc. V. Procházka,Ph.D. (Prof. T. Papajík,CSc.) Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.) Primary (A) and secondary amyloidosis Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.)

3 Examination methods in nephrology Doc.K.Krejčí,Ph.D. (MUDr.K.Žamboch,Ph.D) Acute kidney injury and contrast induced nephropathy Acute and chronic tubulointersticial nephritides and tubular disorders MUDr.K.Žamboch,Ph.D (Doc.K.Krejčí,Ph.D.) MUDr.M.Hrubý (MUDr.J.Orság) Diagnosis and treatment of fluid and electrolyte disorders Acute and rapid progressive glomerulonephritides MUDr.R.Metelka,Ph.D (MUDr.J.Vymětal,Ph.D) MUDr.V.Klementa (MUDr.J.Orság) Diabetic nephropathy and vascular kidney disorders Haemodialysis, peritoneal dialysis and other blood purification methods MUDr. D.Goldmannová (MUDr.K.Žamboch,Ph.D) MUDr.J.Orság (MUDr.M.Hrubý) Diagnosis and treatment of fluid and acid base disorders Epidemiology, etiology and clinical picture of chronic kidney disease MUDr.J.Vymětal,Ph.D (MUDr.R.Metelka,PhD) MUDr. M.Schubertová (MUDr.J.Orság) Kidney transplantation Doc.K.Krejčí,Ph.D. (MUDr.K.Žamboch,Ph.D) 2nd Block Date Block Day Subject No. of ess Examination methods in rheumatology Teacher Pharmacotherapy of rheumatic diseases (NSA, intraarticular therapy, glucocorticoids, sdmards, bdmards, therapy in pregnancy)

4 Systemic lupus erythematosus, antiphospholipid syndrome, Sjögren s syndrome Prof. P.Horák,CSc. Osteoarthritis, crystal induced arthritis, soft tissue rheumatism Prof. V. Ščudla,CSc Vasculitides MUDr.A.Smržová,Ph.D () Systemic scleroderma, idiopathic myositis, overlap syndromes Rheumatoid arthritis and juvenile idiopathic arthritis MUDr.A.Smržová,Ph.D () Prof.P.Horák,CSc. (MUDr. M. Skácelová,Ph.D.) Seronegative spondyloarthritis (ankylosing spondylarthritis, psoriatic arthritis, reactive arthritis), infection and arthritis Metabolic bone diseases (MUDr.M.Skácelová,Ph.D.) MUDr. M. Skácelová,Ph.D. () Adult onset Still disease, paraneoplastic syndromes, musculoskeletal manifestations of endocrine diseases The most important symptoms and examination methods of the endocrine diseases. MUDr. M. Skácelová, Ph.D. Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Hyper- and hypofunction of the pituitary gland, diabetes insipidus. Hypothyroidism, hyperthyroidism, inflammation and tumours of the thyroid gland. Diseases of the parathyroid glands Doc. Z. Fryšák,CSc. (Doc. D. Karásek,Ph.D.) Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Diseases of the adrenal medulla and cortex. Doc. D. Karásek,Ph.D. (Doc. Z. Fryšák,CSc.)

5 Classification and treatment of hyperlipidemias Prof.H.Vaverková,CSc. (Doc. D. Karásek,Ph.D.) ( ) Diagnosis and classification of diabetes mellitus. Acute complications of diabetes. Treatment of type 1 and type 2 diabetes Monitoring of the efficiency of diabetes treatment. The development of the clinical picture, glycated hemoglobin (HbA1c), glycemic profile, conventional self monitoring with glucometer, CGMS (Continuous Glucose Monitoring System). Chronic complications of diabetes. Neuropathy, angiopathy. Specific microvascular complications. Diabetic foot syndrome. Doc. D. Karásek,Ph.D. (MUDr. O. Krystyník) MUDr. O. Krystyník (Doc. D. Karásek,Ph.D.) MUDr.J.Schovánek, PhD. (MUDr. O. Krystyník) MUDr. O. Krystyník (MUDr. D. Číhalíková) ( ) Obesity, the treatment options. MUDr..Cibičková,Ph.D (MUDr. J. Schovánek,Ph.D.) Practical exercises ( ): eading Teacher : Prof. MUDr. P.Horák, CSc. 1st block: nd block: Block Day Subject No. of ess Internal Medicine 39A Dep. of Hematooncology Internal Medicine 39 R-rheumatology Internal Medicine 39C-nephrology Intensive care unit Haemodialysis Intensive care unit Internal Medicine 39A Internal Medicine 39R-rheumatology Haemodialysis 3

6 Block Day Subject No. of ess Internal Medicine 39A Internal Medicine 39R-rheumatology Internal Medicine 39B diabetology Intensive care unit Internal Medicine 39A Internal Medicine 39B- diabetology Internal Medicine 39R-rheumatology Internal Medicine 39C-nephrology Internal Medicine 39A Intensive care unit 3 Absence from the lessons the has to be apologized to the tutor (prof. Horák) or secretary by an (pavel.horak@fnol.cz, marcela.janu@fnol.cz), phone ( , ) or personally. From the four weeks block one day of absence is tolerated in the case of serious personal matter, two days of absence are tolerated in the case of illness. onger absence has to be substituted upon an appointment with the tutor (vice tutor). The substitution can be accomplished within another block (preferred option) or at the end of the term and can contain the work at the department as well as the elaboration of the seminar. It s strongly recommended to resolve the longer and expected absence as soon as possible. Completed by : Credit, Exam Requirements : Active attendance at exercises and seminars iterature : 1. T.E. Andreoli: Cecil Essentials of Medicine, 9ed (2016) 2. Č.Číhalík, M. Taborský: EKG v klinické praxi (Solen, 2013) 3.. Chrobák: Physical Examination in Internal Medicine, Avicenum, Grada Publishing (2003) Alternative sources: 4. Kaspers DE et al. or Jameson et al. : Harrison s Principles of Internal Medicine 19/E or 20/Ed, MC Craw-Hill, 19 th or 20 th Edition, New York (2015 or 2018) 5. A.T. Raftery et al.: Churchill s pocketbook of differential diagnosis, 4 th Edition Elsevier Canada; (2014) 6. Kinirons M. et al. French s Index of Differential diagnosis CRC Press (2016) 7. Ralston S. et al. Davidson s Principles and Practice of Medicine. 23h edition, Elsevier (2018) 8. Kumar P., Clark M. Kumar s and Clarkś Clinical Medicine, 9th Edition, Elsevier (2016) 9. Wilkinson IB. Oxford handbook of clinical medicine. Oxford university press (2017)

7 Program of Study : General Medicine Course : Internal Medicine III, A2 Abbreviation : IN3/VA012 Schedule : 1st block: nd block: Course Distribution : 5 year, 9 and 10 semester, Number of Credits : 10 Course Form : ectures, seminars, exercises Seminars (S) and lectures (): eading teacher: Teachers : Prof. MUDr. J. Zadražil, CSc. Prof. MUDr. V. Ščudla, CSc. Prof. MUDr. K. Indrák, DrSc. Prof. MUDr. H. Vaverková, CSc. Prof. MUDr. P. Horák, CSc. Prof. MUDr. T. Papajík, CSc. Prof. MUDr. E. Faber, CSc. Doc. MUDr. J. Bačovský, CSc Doc. MUDr. Z. Fryšák, CSc. Doc. MUDr. D. Karásek, Ph.D Doc. MUDr. K. Krejčí, Ph.D Doc. MUDr. V. Procházka, Ph.D Doc. MUDr. P. Rohoň, Ph.D Doc. MUDr. T. Szotkowski, Ph.D Prim. MUDr. D. Galuszková, Ph.D MUDr. A. Smržová, Ph.D MUDr. A. Hluší, Ph.D MUDr.. Raida, Ph.D MUDr. R. Metelka, Ph.D MUDr. M. Halenka, Ph.D MUDr. J. Vymětal, Ph.D MUDr.. Cibičková, Ph.D. MUDr. K. Žamboch,Ph.D MUDr. J. Schovánek, Ph.D. MUDr. M. Skácelová, Ph.D. MUDr. M. Schubertová MUDr. M. Hrubý MUDr. J. Orság MUDr. O. Krystyník MUDr. D. Číhalíková MUDr. V. Klementa MUDr. M. Palová

8 Study: Block 1st Blocks date: Start of teaching block take place in the lecture room of the 3rd Department of Internal Medicine - Dept. 39 A (first floor) ,45 h. ectures () and seminars (, ) take place in the lecture room of the 3rd Department of Internal Medicine ( ) or Department of Haematooncology ( ) Block Day Subject No. of ess Start of teaching block Teacher (MUDr. J. Schovánek,PhD.) ( ) Acute leukaemias, myelodysplastic syndrome Doc. P. Rohoň,Ph.D. (Doc.T.Szotkowski,PhD.) Hereditary and acquired haemolytic anaemias, haemoglobinopathies Chronic myeloid leukaemia, Phnegative myeloproliferative disorders Prof. K. Indrák,DrSc. (MUDr.. Raida,Ph.D) Prof. E. Faber,CSc. (Prof. K. Indrák,DrSc.) 3 ( ) Diagnostics, classification and treatment of bleeding disorders Holiday MUDr. A. Hluší,Ph.D (MUDr. M. Palová) Polycythaemia vera and other polycythemias, differential diagnosis and therapy Chronic lymphoprolipherative disorders Diagnosis and treatment of monoclonal gamapathies Prof. K. Indrák,DrSc. (Prof. E. Faber,CSc.) Doc. V. Procházka,PhD. (Prof. T. Papajík,CSc.) Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.) Primary (A) and secondary amyloidosis Examination methods in nephrology Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.) Doc. K. Krejčí,Ph.D. (MUDr.K.Žamboch,Ph.D) Acute kidney injury and contrast induced nephropathy MUDr.K.Žamboch,Ph.D (Doc.K.Krejčí,PhD.)

9 Acute and chronic tubulointersticial nephritides and tubular disorders Diagnosis and treatment of fluid and electrolyte disorders Acute and rapid progressive glomerulonephritides MUDr.M.Hrubý (MUDr.J.Orság) MUDr.R.Metelka,Ph.D (MUDr.J.Vymětal,Ph.D) MUDr.V.Klementa (MUDr.J.Orság) Diabetic nephropathy and vascular kidney disorders Haemodialysis, peritoneal dialysis and other blood purification methods MUDr. D.Goldmannová (MUDr.K.Žamboch,Ph.D) MUDr.J.Orság (MUDr.M.Hrubý) Diagnosis and treatment of fluid and acid base disorders Epidemiology, etiology and clinical picture of chronic kidney disease MUDr.J.Vymětal,Ph.D (MUDr.R.Metelka,PhD) MUDr. M.Schubertová (MUDr.J.Orság) Kidney transplantation Doc.K.Krejčí,Ph.D. (MUDr.K.Žamboch,Ph.D) 2nd Block Date Block Day Subject No. of ess Examination methods in rheumatology Teacher Pharmacotherapy of rheumatic diseases (NSA, intraarticular therapy, glucocorticoids, sdmards, bdmards, therapy in pregnancy) Systemic lupus erythematosus, antiphospholipid syndrom, Sjögren s syndrome Prof. P.Horák,CSc. Osteoarthritis, crystal induced arthritis, soft tissue rheumatism Prof. V. Ščudla,CSc.

10 Vasculitides MUDr.A.Smržová,Ph.D () Systemic scleroderma, idiopathic myositis, overlap syndromes Rheumatoid arthritis and juvenile idiopathic arthritis MUDr.A.Smržová,Ph.D (prof. P. Horák,CSc.) Prof.P.Horák,CSc. (MUDr.M.Skácelová,Ph.D.) Seronegative spondyloarthritis (ankylosing spondylarthritis, psoriatic arthritis, reactive arthritis), infection and arthritis Metabolic bone diseases Adult onset Still disease, paraneoplastic syndromes, musculoskeletal manifestations of endocrine diseases The most important symptoms and examination methods of the endocrine diseases. (MUDr.M.Skácelová Ph.D.) MUDr. M. Skácelová, Ph.D. () MUDr.M.Skácelová,Ph.D. (MUDr.ASmržová,Ph.D) Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Hyper- and hypofunction of the pituitary gland, diabetes insipidus. Hypothyroidism, hyperthyroidism, inflammation and tumors of the thyroid gland. Diseases of the parathyroid glands Doc. Z. Fryšák.CSc. (Doc. D. Karásek,Ph.D.) Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Diseases of the adrenal medulla and cortex. Classification and treatment of hyperlipidemias Doc. D. Karásek,Ph.D. (MUDr.J.Schovánek,Ph.D.) Prof.H.Vaverková,CSc. (Doc. D. Karásek,Ph.D.) Diagnosis and classification of diabetes mellitus. Acute complications of diabetes. Doc. D. Karásek,Ph.D. (MUDr. O. Krystyník)

11 Treatment of type 1 and type 2 diabetes Monitoring of the efficiency of diabetes treatment. The development of the clinical picture, glycated hemoglobin (HbA1c), glycemic profile, conventional selfmonitoring with glucometer, CGMS (Continuous Glucose Monitoring System). MUDr. O. Krystyník (Doc. D. Karásek,Ph.D.) MUDr. J.Schovánek,PhD. (MUDr. O. Krystyník) Chronic complications of diabetes. Neuropathy, angiopathy. Specific microvascular complications. Diabetic foot syndrome. MUDr. O. Krystyník (MUDr. D. Číhalíková) Obesity, the treatment options. MUDr..Cibičková,Ph.D (MUDr.J.Schovánek,Ph.D.) Practical exercises ( ): eading Teacher : Prof. MUDr. P. Horák, CSc. Study : Block Block Date : and Block Day subject No. of ess Internal Medicine 39A Hematology Holiday Internal Medicine 39B-nephrology Dep. of Hematooncology Internal Medicine 39A Haemodialysis Internal Medicine 39A Internal Medicine 39A-rheumatology Haemodialysis 3

12 Block Day Subject No. of ess Internal Medicine 39A Internal Medicine 39A-rheumatology Internal Medicine 39B-diabetology Intensive care unit Internal Medicine 39A Internal Medicine 39B-diabetology Internal Medicine 39A-rheumatology Internal Medicine 39B -nephrology Internal Medicine 39A Intensive care unit 3 Absence from the lessons the has to be apologized to the tutor (prof. Horák) or secretary by an (pavel.horak@fnol.cz, marcela.janu@fnol.cz), phone ( , ) or personally. From the four weeks block one day of absence is tolerated in the case of serious personal matter, two days of absence are tolerated in the case of illness. onger absence has to be substituted upon an appointment with the tutor (vice tutor). The substitution can be accomplished within another block (preferred option) or at the end of the term and can contain the work at the department as well as the elaboration of the seminar. It s strongly recommended to resolve the longer and expected absence as soon as possible. Completed by : Credit, Exam Requirements : Active attendance at exercises and seminars iterature : 1. T.E. Andreoli: Cecil Essentials of Medicine, 9ed (2016) 2. Č.Číhalík, M. Taborský: EKG v klinické praxi (Solen, 2013) 3.. Chrobák: Physical Examination in Internal Medicine, Avicenum, Grada Publishing (2003) Alternative sources: 4. Kaspers DE et al. or Jameson et al. : Harrison s Principles of Internal Medicine 19/E or 20/Ed, MC Craw-Hill, 19 th or 20 th Edition, New York (2015 or 2018) 5. A.T. Raftery et al.: Churchill s pocketbook of differential diagnosis, 4 th Edition Elsevier Canada; (2014) 6. Kinirons M. et al. French s Index of Differential diagnosis CRC Press (2016) 7. Ralston S. et al. Davidson s Principles and Practice of Medicine. 23h edition, Elsevier (2018) 8. Kumar P., Clark M. Kumar s and Clarkś Clinical Medicine, 9th Edition, Elsevier (2016) 9. Wilkinson IB. Oxford handbook of clinical medicine. Oxford university press (2017)

13 Program of Study : General Medicine Course : Internal Medicine III, A3 Abbreviation : IN3/VA012 Schedule : 1st block: nd block: Course Distribution : 5 year, 9 and 10 semester, Number of Credits : 10 Course Form : ectures, seminars, exercises Seminars (S) and lectures (): eading teacher: Teachers : Prof. MUDr. J. Zadražil, CSc. Prof. MUDr. V. Ščudla,CSc. Prof. MUDr. K. Indrák, DrSc. Prof. MUDr. H. Vaverková, CSc. Prof. MUDr. P. Horák, CSc. Prof. MUDr. T. Papajík, CSc. Prof. MUDr. E. Faber, CSc. Doc. MUDr. J. Bačovský, CSc Doc. MUDr. Z. Fryšák, CSc. Doc. MUDr. D. Karásek, Ph.D Doc. MUDr. K. Krejčí, Ph.D Doc. MUDr. V. Procházka, Ph.D Doc. MUDr. P. Rohoň, Ph.D Doc. MUDr. T. Szotkowski, Ph.D Prim. MUDr. D. Galuszková, Ph.D MUDr. A. Smržová, Ph.D MUDr. A. Hluší, Ph.D MUDr.. Raida, Ph.D MUDr. R. Metelka, Ph.D MUDr. M. Halenka, Ph.D MUDr. J. Vymětal, Ph.D MUDr.. Cibičková, Ph.D. MUDr. K. Žamboch, Ph.D MUDr. J. Schovánek, PhD. MUDr. M. Skácelová, Ph.D. MUDr. D. Goldmannová MUDr. Z. Kosatíková MUDr. M. Hrubý MUDr. J. Orság MUDr. O. Krystyník MUDr. D. Číhalíková MUDr. V. Klementa MUDr. M. Palová

14 Study: Block 1st block: Start of teaching block take place in the lecture room of the 3rd Department of Internal Medicine - Dept. 39 A (first floor) ,45 h. ectures () and seminars (, ) take place in the lecture room of the 3rd Department of Internal Medicine ( ) or Department of Haematooncology ( ) Block Day Subject No. of ess Start of teaching block Teacher (MUDr. J. Schovánek,PhD.) ( ) Acute leukaemias, myelodysplastic syndrome Doc. P. Rohoň,PhD. (Doc.T. Szotkowski,PhD.) Hereditary and acquired haemolytic anaemias, haemoglobinopathies Chronic myeloid leukaemia, Phnegative myeloproliferative disorders Prof. K. Indrák,DrSc. (MUDr.. Raida,Ph.D) Prof. E. Faber,CSc. (Prof. K. Indrák,DrSc.) Diagnostics, classification and treatment of bleeding disorders Thrombophilic disorders MUDr. A. Hluší,Ph.D (MUDr. M. Palová) MUDr. M. Palová (MUDr. A. Hluší,Ph.D) Malignant lymphomas Polycythaemia vera and other polycythemias, differential diagnosis and therapy Chronic lymphoprolipherative disorders Diagnosis and treatment of monoclonal gamapathies Doc. V. Procházka,PhD. (Prof. T. Papajík,CSc.) Prof. K. Indrák,DrSc. (Prof. E. Faber,CSc.) Doc. V. Procházka,PhD. (Prof. T. Papajík,CSc.) Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.) Primary (A) and secondary amyloidosis Examination methods in nephrology Doc. J. Bačovský,CSc. (Prof. V. Ščudla,CSc.) Doc. K. Krejčí,PhD. (MUDr.K.Žamboch,Ph.D) Acute kidney injury and contrast induced nephropathy MUDr.K.Žamboch,Ph.D (Doc. K. Krejčí,PhD.)

15 Acute and chronic tubulointersticial nephritides and tubular disorders MUDr. M. Hrubý (MUDr. J. Orság) Diagnosis and treatment of fluid and electrolyte disorders Acute and rapid progressive glomerulonephritides MUDr.R.Metelka,Ph.D (MUDr.J.Vymětal,Ph.D) MUDr.V.Klementa (MUDr. J. Orság) Diabetic nephropathy and vascular kidney disorders Haemodialysis, peritoneal dialysis and other blood purification methods MUDr.D.Goldmannová (MUDr.K.Žamboch,Ph.D) MUDr.J.Orság (Mudr.M.Hrubý) Diagnosis and treatment of fluid and acid base disorders Epidemiology, etiology and clinical picture of chronic kidney disease MUDr.J.Vymětal,Ph.D (MUDr.R.Metelka,Ph.D) MUDr.M.Schubertová (MUDr. J. Orság) Kidney transplantation Doc. K. Krejčí,PhD. (MUDr.K.Žamboch,Ph.D) 2nd block: Block Day Subject No. of ess Holiday Teacher Holiday Vasculitides MUDr.A.Smržová,Ph.D () Systemic scleroderma, idiopathic myositis, overlap syndromes Rheumatoid arthritis and juvenile idiopathic arthritis MUDr.A.Smržová,Ph.D (prof. P. Horák,CSc.) (MUDr.M.Skácelová,Ph.D.) Seronegative spondyloarthritis (ankylosing spondylarthritis, psoriatis arthritis, reactive arthritis), infection and arthritis Prof. P. Horák, CSc. (MUDr.M.Skácelová,Ph.D.)

16 Metabolic bone diseases MUDr. M. Skácelová,Ph.D. (Prof. P. Horák, CSc.) Adult onset Still disease, paraneoplastic syndromes, musculoskeletal manifestations of endocrine diseases The most important symptoms and examination methods of the endocrine diseases. MUDr.M.Skácelová,Ph.D. Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Hyper- and hypofunction of the pituitary gland, diabetes insipidus. Hypothyroidism, hyperthyroidism, inflammation and tumours of the thyroid gland. Diseases of the parathyroid glands Doc. Z. Fryšák,CSc. (Doc. D. Karásek,PhD.) Doc. Z. Fryšák,CSc. (MUDr.M.Halenka,Ph.D) Diseases of the adrenal medulla and cortex. Classification and treatment of hyperlipidemias Doc. D. Karásek,Ph.D. (Doc. Z. Fryšák,CSc.) Prof. H. Vaverková,CSc. (Doc. D. Karásek,PhD.) Diagnosis and classification of diabetes mellitus. Acute complications of diabetes. Treatment of type 1 and type 2 diabetes Doc. D. Karásek,Ph.D. (MUDr. O. Krystyník) MUDr. O. Krystyník (Doc. D. Karásek,PhD.) Monitoring of the efficiency of diabetes treatment. The development of the clinical picture, glycated hemoglobin (HbA1c), glycemic profile, conventional self monitoring with glucometer, CGMS (Continuous Glucose Monitoring System). Chronic complications of diabetes. Neuropathy, angiopathy. Specific microvascular complications. Diabetic foot syndrome. MUDr.J. Schovánek, PhD. (MUDr. O. Krystyník) MUDr. O. Krystyník (MUDr. D. Číhalíková) Obesity, the treatment options. MUDr..Cibičková,Ph.D (MUDr. J.Schovánek,Ph.D.)

17 Practical exercises ( ): eading Teacher : Study : Block Date : Prof. MUDr. P. Horák, CSc. Block 1st block: nd block: Block Day Subject No. of ess Internal Medicine 39A Dep. of Hematooncology Internal Medicine 39 A-rheumatology Internal Medicine 39B-nephrology Dep. of Hematooncology Internal Medicine 39 A Haemodialysis Internal Medicine 39A Internal Medicine 39A-rheumatology Haemodialysis 3 Block Day Subject No. of ess Holiday Holiday Internal Medicine 39B-diabetology Intensive care unit Internal Medicine 39A Internal Medicine 39B-diabetology Internal Medicine 39-rheumatology Internal Medicine 39 B-nephrology Internal Medicine 39A Intensive care unit 3 Absence from the lessons the has to be apologized to the tutor (prof. Horák) or secretary by an (pavel.horak@fnol.cz, marcela.janu@fnol.cz), phone ( , ) or personally. From the four weeks block one day of absence is tolerated in the case of serious personal matter, two days of absence are tolerated in the case of illness. onger absence has to be substituted upon an appointment with the tutor (vice tutor). The substitution can be accomplished within another block (preferred option) or at the end of the term and can contain the work at the department as well as the elaboration of the seminar. It s strongly recommended to resolve the longer and expected absence as soon as possible.

18 Completed by : Requirements : iterature : Credit, Exam Active attendance at exercises and seminars 1. T.E. Andreoli: Cecil Essentials of Medicine, 9ed (2016) 2. Č.Číhalík, M. Taborský: EKG v klinické praxi (Solen, 2013) 3.. Chrobák: Physical Examination in Internal Medicine, Avicenum, Grada Publishing (2003) Alternative sources: 4. Kaspers DE et al. or Jameson et al. : Harrison s Principles of Internal Medicine 19/E or 20/Ed, MC Craw-Hill, 19 th or 20 th Edition, New York (2015 or 2018) 5. A.T. Raftery et al.: Churchill s pocketbook of differential diagnosis, 4 th Edition Elsevier Canada; (2014) 6. Kinirons M. et al. French s Index of Differential diagnosis CRC Press (2016) 7. Ralston S. et al. Davidson s Principles and Practice of Medicine. 23h edition, Elsevier (2018) 8. Kumar P., Clark M. Kumar s and Clarkś Clinical Medicine, 9th Edition, Elsevier (2016) 9. Wilkinson IB. Oxford handbook of clinical medicine. Oxford university press (2017)