Semester I 2013/2014. Clinical Medicine & Pathology 316
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1 Semester I 2013/2014 Clinical Medicine & Pathology 316 Course Content Outline/Lecture Details & Timetable: 1. Introduction to Pathology Part I: Sunday* 01/09/13 (MD)*** a. Course introduction. b. Pathology & disease. -- Definitions & general understanding. c. Cell injury. -- Basic types, compositions, causes & types of cell injury. 2. Introduction to Pathology Part II: Tuesday** 03/09/13 (MD) a. Manifestations of diseases. -- Overview on symptoms & abnormalities. b. Structural & functional diseases. -- General understanding of organic diseases & pathophysiologic changes. c. Causes of diseases & patient care. -- Overview on exogenous/endogenous causes & patient care. 3. Infectious Diseases Part I: Sunday 08/09/13 (LV)*** a. Infection and body defense system. -- Microorganisms & overall impact of infectious disease. b. Specific diseases part I. -- Bacterial infections in general & viral infections in general. 4. Infectious Diseases Part II: Tuesday 10/09/13 (LV) a. Specific diseases part II. -- Fungal infections & other infectious diseases (parasites). b. Immune system. -- Natural immunity, acquired immunity, transplantation immunology & immunodeficiency. 5. Inflammation and Repair: [QUIZ 1] Sunday 15/09/13 (LV) a. Review of inflammation. -- Acute, chronic, granulomatous & gross inflammatory lesions. b. Repair. -- Regeneration, fibrous connective tissue repair & wound repair. 6. Neoplasia Part I: Tuesday 17/09/13 (MD) a. Disturbance of growth & cancer. -- Hyperplasia, hypertrophy, nature of neoplasia & causes of cancer. b. Characteristics of tumors. -- Benign, malignant, staging and symptoms.
2 7. Neoplasia Part II: Sunday 22/09/13 (MD) a. Tumor immunity & cancer therapy. -- Immune surveillance, spontaneous regression, cancer therapy & radiation. b. Inherited disease. -- Genetic information, chromosomal aberrations, multifactorial disorders, genetic screening & treatment. 8. Dermatology & Burns: [QUIZ 2] Tuesday 24/09/13 (MD) a. Diseases of the skin. -- Infections, noninfectious inflammation, vesicular diseases, drug eruption & disorders of pigmentation. b. Classifications of burn. -- Burn causes, diagnosis, symptoms & treatment. 9. Musculoskeletal System Part I: Sunday 29/09/13 (AA)*** -- Muscle fibers, bone, cartilage & bone function. b. Joints. -- Structure & function. c. Symptoms, signs and tests. -- Weakness & atrophy, pain, serum enzymes & muscle biopsy. 10. Musculoskeletal System Part II: Tuesday 01/10/13 (AA) a. Genetic/developmental diseases. -- Duchenne dystrophy, myotonic dystrophy & other dystrophies. b. Metabolic bone diseases. -- Osteoporosis, osteomalacia, osteomyelitis & tuberculosis. c. Arthritis. -- Rheumatoid arthritis, etiology, lesions, symptoms, types & treatment. 11. Respiratory System Part I: Sunday 06/10/13 (CM)*** -- Ventilation and perfusion, trachea and bronchi & respiratory tract defense mechanisms. b. Diseases. -- Larynx, lungs, & restrictive pulmonary diseases. 12. Respiratory System part II: [QUIZ 3] Tuesday 08/10/13 (CM) a. Infectious diseases. -- Bacterial pneumonias, viral pneumonias, aspiration pneumonia & pleura. b. Other diseases. -- Abscess, pulmonary tuberculosis, bronchitis, asthma & pneumothorax.
3 13. MIDTERM EXAMINATION SUNDAY 20/10/13 (ALL) 14. Cardio-vascular System & Lymphatics Part I: Tuesday 22/10/13 (AA) -- Great vessels, chambers, blood flow, blood cells, lymphoid tissue, bone marrow & production and destruction of red blood cells. b. Cardiac failure. -- Overview of cardiac failure. c. Congenital heart diseases. -- Arteriovenous shunts, venous-arterial shunts, stenosis of the pulmonary artery & miscellaneous anomalies. 15. Cardio-vascular System & Lymphatics Part II: [QUIZ 4] Sunday 27/10/13 (AA) a. Arterial diseases. -- Atherosclerosis, nonatheromatous arteriosclerosis & arteriolosclerosis. b. Hypertension. -- Definition, etiology, signs & treatment. c. Myocarditis. -- Rheumatic heart disease & trypanosome cruzi and toxoplasma gondii. 16. Cardio-vascular System & Lymphatics Part III: Tuesday 29/10/13 (AA) a. Organ failure. -- Shock, congestion, edema & elephanantiasis. b. Inflammatory/degenerative diseases of the lymph. -- Anemias in general, disorders of white cells & disorders of platelets. c. Hyperplastic/neoplastic diseases. -- Polycythemia, leukemias, lymphomas & multiple myeloma. 17. Endocrine System: Sunday 03/1/13 (TBA)*** -- Organs, hormones & their effects. b. Diseases of the pituitary gland. -- Panhypopituitarism, diabetes insipidus & pituitary tumors. c. Diseases of the thyroid gland. -- Hypothyroidism, hyperthyroidism & thyroid neoplasms. d. Diseases of the adrenal glands. -- Addison s disease, conn s syndrome & neuroblastoma. 18. Gastrointestinal System Part I: Sunday 10/11/13 (CM) -- Upper & lower digestive tracts. b. Oral-pharyngeal cavity.
4 -- Oral cancer, Leukoplakia, prognosis of carcinoma, salivary gland tumors, & tooth diseases. c. Esophagus. -- Lesions, lacerations, & neoplasms. 19. Gastrointestinal System Part II: [QUIZ 5] Tuesday 12/11/13 (CM) a. Stomach. -- Gastritis, ulceration, & neoplasms. b. Small intestine. -- Inflammations, malabsorption & obstruction. c. Appendix & the colon. -- Appendicitis, megacolon, inflammation & neoplasms. 20. Central Nervous System Part I: Sunday 19/11/13 (AAM) -- Cortex and white matter, meninges, cerebrospinal fluid & vessels. b. Symptoms, signs and tests. -- cognitive and motor dysfunction, focal and generalized dysfunction, angiograms & imaging modalities. c. Genetic/developmental diseases. -- Malformations & destructive brain lesions. 21. Central Nervous System Part II: [QUIZ 6] Tuesday 24/11/13 (AAM) a. Inflammatory/degenerative diseases. -- Meningitis, encephalitis, cerebrovascular accident (stroke), trauma, multiple sclerosis, parkinson s disease & epilepsy. b. Hyperplastic/neoplastic diseases. -- Brain neoplasms. 22. Female Reproductive System: Tuesday 26/11/13 (MD) -- Vulva, vagina, uterus, fallopian tubes & ovaries. b. Symptoms, signs and tests. -- Bleeding, pain, discharge, pelvic examination & pap smear. c. Inflammatory/degenerative diseases. -- Syphilis, superficial vaginal infections & condyloma acuminatum. d. Hyperplastic/neoplastic diseases. -- Carcinoma of the cervix & ovarian tumors. e. Diseases of pregnancy. -- Spontaneous abortion, ectopic pregnancy & septic abortion. 23. Urinary System Part I: Sunday 01/12/13 (MD)
5 -- Kidneys, ureters, bladder, urethra, testes & prostate. b. Most frequent problems. -- Cystitis, prostate enlargement, renal calculi & carcinoma of bladder and prostate. c. Genetic/developmental diseases. -- Agenesis and hypoplasia, polycystic Kidneys & dyplastic kidney. 24. Urinary Systems II: [QUIZ 6] Tuesday 03/12/13 (MD) a. Inflammatory/degenerative diseases. -- Kidney stones, cystitis, prostatitis & glomerular diseases. b. Hyperplastic/neoplastic diseases. -- Hyperplasia of the prostate, adenocarcinoma of the prostate, cancers of kidneys & cancers of testis. c. Organ failure. -- Acute renal failure & chronic renal failure. 25. FINAL EXAMINATION (TBA) Coordinator: Dr. Mohsen Dashti (RS). Co-teachers: Prof. Chacko Mathew (MLS). Dr. Akram Asbeutah (RS). Dr. Leila Vali (MLS). Dr. Aseel Almeqbel (HS). * SUNDAYs (All lectures from 2-3 pm) ** TUESDAYs (All lectures from 2-4 pm) *** MD: Dr. Mohsen Dashti CM: Prof. Chacko Mathew AA: Dr. Akram Asbeutah LV: Dr. Leila Vali AAM: Dr. Aseel Almeqbel Evaluation Procedure: Determination of the final grade for this course will be based upon the following: Quiz (7) - 20% Mid-semester examination - 30% Final examination - 50% Total - 100%
6 Required Text books: Boyd and Sheldon. Introduction to the study of disease. Latest edition. Philadelphia: Lea & Febiger. Kent and Hart. Introduction to human disease. Third edition. Connecticut: Appleton & Lance. Revised by Dr. Mohsen Dashti 01/09/2013
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