Risk factors of gestational diabetes mellitus among the re-birth pregnant women in Xiamen City in
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1 JOURNAL OF HYGIENE RESEARCH Vol. 46 No. 6 Nov 檾檾檾檾 DANONE INSTITUTE CHINA Young Scientists' Forum 檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾檾 gestational diabetes mellitus GDM GDM GDM ± kg vs ± kg t = P = /393 vs 38 /393 χ 2 = P = GDM Z = P = χ 2 = P = χ 2 = P = χ 2 = P = GDM GDM 3. 8 kg OR = Logistic GDM kg OR = P = kg GDM 3. 8 kg GDM R R A Risk factors of gestational diabetes mellitus among the re-birth pregnant women in Xiamen City in Fan Yanfeng Xu Rongxian Cai Lili Cai Liqian Maternal and Child Health Hospital Xiamen China Abstract Objective GDM among the re-birth pregnant women. Methods No fyf8011@ 163. com 1 rong1963cn@ aliyun. com To discuss the risk factors of the gestational diabetes mellitus A total of 393 pregnant women with GDM were collected randomly according to the number of the antenatal care manual in the Maternal and Child Health Hospital in Xiamen City. Meanwhile 393 pregnant women with normal glucose tolerance were chosen to be the control group matching with
2 age of the GDM group. Their basic data would be analyzed including the BMI before pregnancy the degree of the education the times of the abortion the body weight gain during the pregnancy their parental diabetes history the birth weight of the last fetal the history of GDM and so on. The two groups of people were re-birth pregnant women. Results Single factor analysis showed that among the GDM group the total body weight gain before the 24th week ± kg and the proportion of their mothers with the DM 64 /393 were both higher than the control group ± kg and 38 /393 however the degree of the education was lower than the control group. Paired chi-square analysis showed that the history of macrosomia delivery χ 2 = P = the history of GDM χ 2 = P = and abortion history more than 2 times χ 2 = P = were the risk factors of GDM for those women. Meanwhile with the increasing of the fetal birth weight the risk of being the GDM during the second pregnancy was also increasing. When the fetal birth weight reached 3. 8 kg OR = the risk value reached a strong correlation. Multiple factors Logistic regression analysis showed those factors of GDM also had statistically significant differences especially the bodyweight gain before the 24th week over 10 kg played the most important role during the pregnancy OR = P = Conclusion The risk factors of the GDM for the re-birth pregnant women concluded the history of GDM the history of macrosomia the times of the abortion over twice the bodyweight gain before the 24th week over 10 kg the low degree of the education the pregnant women s mother had the DM. For those pregnant women with fetal birth weight above 3. 8 kg they should be included in the high risk population of GDM during the next pregnancy. Key words re-birth gestational diabetes mellitus risk factors gestational diabetes mellitus GDM GDM GDM 393 body mass index BMI = 1 kg / m 2 BMI < ~ GDM ~ g 24 ~ mmol /L 1 h 10. 0
3 mmol /L 2 h 8. 5 mmol /L 2. 1 GDM SPSS t χ 2 Logistic GDM Z = P = n = 393 n = 393 t /χ 2 /Z P / ± ± t = /kg ± ± t = ± ± t = χ 2 = χ 2 = Z = / GDM 2 2 P < OR χ 2 1 P OR 95% CI ~ ~ ~ ~ McNema Logistic 3 Logistic kg OR = P = kg OR GDM ~ kg OR = P = ~ ~ GDM OR = P =
4 /kg a b c d χ 2 P OR 95% CI ~ ~ ~ ~ ~ ~ ~ ~ ~ a < b < c < d 4 Logistic = 0 = 1 < 2 = 0 2 = 1 24 < 10 kg = 0 10 kg = 1 = 0 = 1 1 = 2 = 3 = 4 = < 3. 5 kg = kg 3. 6 kg = kg 3. 7 kg = kg 3. 8 kg = kg 3. 9 kg = kg 4. 0 kg = = Logistic B SE Wald OR 95% CI P ~ ~ ~ ~ ~ ~ ~ 12 GDM 8 GDM GDM GDM 9 GDM 1 1 GDM 2 OR = P = OR = P = GDM 10 χ 2 = P = BATTISTA 11 GDM GDM GDM GDM GDM GDM
5 Study Groups Consensus Panel. International GDM association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy J. Diabetes Care kg GDM Logistic 6. OR OR = P = J M kg OR = OR = J. GDM OR TCF7L2 J. GDM GDM 10 NOLAN C J DAMM P PRENTKI M. Type-2 diabetes across generations from pathophysiology to J. 11 BATTISTA M C HIVERT M F DUVAL K et al J J J M International Association of Diabetes and Pregnancy prevention and management J. Lancet Intergenerational cycle of obesity and diabetes how can we reduce the burdens of these conditions on the health of future generations J. Exp Diabetes Res J MACFARLANE D J LEE C C HO E Y et al. 13 SHORT K R VITTONE J L BIGELOW M L et al. Impact of aerobic exercise training on age-related. changes in insulin sensitivity and muscle oxidative capacity J. Diabetes MARQUES-VIDAL P VOLLENWEIDER P Reliability and validity of the Chinese version of IPAQ short last 7days J. Sci Med Sport FUNG T T CHIUVE S E MCCULLOGUH M L et WAEBER G. Alcohol consumption and incidence of type 2 diabetes. Results from the CoLaus study J. Nutr Metab Cardiovasc Dis HILDING A ERIKSSON A K AGARDH E E et al. al. Adherence to a DASH-style diet and risk of The impact of family history of diabetes and lifestyle coronary heart disease and stroke in women J. Arch Int Med HEIANZA Y ARASE Y SAITO K et al. Role of factors on abnormal glucose regulation in middle-aged Swedish men and women J. Diabetologia alcohol drinking pattern in type 2 diabetes in 16. Japanese men the toranomon hospital health 2 J. management center study 11 J. Am J Clin Nutr
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