National liver offering scheme
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1 1 National liver offering scheme Outline 1 Hub Specialist Nurse Organ Donation (SNOD) registers donor with Operations 2 matching Hub Operations initiates the run 3 Hub Matching run offering list printed and also saved in electronic file by Operations 4 matching Hub Operations offers organs to recipients according to the run offering list 5 accept Hospitals have 45 minutes to consider their offer and either or decline 6 pass, If three centres decline for a donor or organ function reason, or five hours fast track offer may be initiated 7 all Acceptance of offer or centre decline and patients will remain categorised in the same way
2 2 National liver offering scheme Summary Specialist Nurse Organ Donation (SNOD) registers the donor with Hub Operations Hub Operations initiates matching run Matching run based on: 7 donor characteristics and 21 recipient characteristics Matching run includes seven tiers: 1. Super urgent 2. Hepatoblastoma 3. Intestinal 4. Liver and cardiothoracic 5. Split liver 6. Elective liver patients (e.g. everyone on the Liver Transplant List), offered by the transplant benefit score (TBS) for either chronic liver disease and hepatocellular carcinoma (CLD/HCC) or variant syndrome. 7. Fast track If the centre declines due to donor or organ being unsuitable, the hospital will be asked to clarify whether this is for a named patient, or all patients on the hospital s list Liver offers made by Hub Operations, not SNOD including split liver offering Centre has 45 minutes to consider the offer If 3 centres decline for a donor or organ function reason, or after 5 hours, the organ goes to fast track offer If patient meets split liver criteria: Left lateral paediatric and small adult Right lateral or whole liver adult Acceptance of offer or all centre decline
3 3 Fast track offering Three declines for a donor or function related reason will trigger a fast track offer. Fast track offering made by Hub Operations, not SNOD for all offers Each centre has 45 minutes to consider the offer and call in to accept the offer If more than one centre is interested in the offer, the organ offer will be given to the centre with the highest ranked transplant benefit score (TBS) patient Hub Operations will only inform the centre if their patient has been allocated the organ. If a centre does not receive a call they will know they did not have the highest TBS and they are not allocated the organ Hub Operations will then ring the SNOD to say that the organ has been accepted, or will inform the SNOD there has been an All centre decline
4 4 Matching run Priority is always given to those on the super urgent list (those who will not live long without a transplant), patients with hepatoblastoma and those waiting for a multi organ transplant (intestinal / liver and cardiothoracic). The liver is then offered to patients on the Liver Transplant List with the highest transplant benefit score (TBS). The highest ranked patient with the best match will be the first to be offered the liver. If the liver is accepted and the transplant proceeds, the recipient will be removed from the transplant list within 24 hours.
5 5 Split liver offering If the donor meets the criteria for a split liver: the liver will be offered first for named hepatoblastoma patients (If the recipient is a padiatric or small adult, the centre can accept the split and keep the right lateral.) the offer is then made to paediatric and small adults using a centre allocation which is on a zonal basis then on a centre basis the right lateral or whole liver will be offered to adults based on the transplant benefit score, on a named patient basis
6 6 Transplant benefit score applies to CLD and HCC recipients Transplant benefit scores are computed using the 21 recipient criteria and the 7 donor criteria. As the donor changes so will the benefit score so recipients ranked highest on one matching run may not appear in the same rank with another donor.
7 7 Donor criteria: Age Cause of death BMI (height and weight) Diabetes Donor type Blood group Split liver criteria
8 8 Recipient criteria: Age Gender Hepatitis C Disease group Creatanine Biliruben INR Sodium Potassium Albumin Renal support Inpatient status Previous abdominal surgery Encephalopathy Ascitis Time on waiting list Diabetes Maximum AFP level Maximum tumour size Two tumours Three or more tumours
9 9 Variant syndrome patients The computer will produce a matching run for variant syndrome patients with a frequency based on the statistical incidence of patients registered as variant syndrome patients. This currently stands at 3% of patients on the transplant waiting list. Therefore, on average, around 3 in every 100 matching runs will be for variant syndrome patients. These recipients will be ranked in the offering sequence according to how long they have been registered on the waiting list.
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