PMH: No medications; Immunizations UTD No hospitalizations or surgeries Speech Delay. Birth Hx: 24 WGA, NICU x6 months
|
|
- Ruth Gibson
- 6 years ago
- Views:
Transcription
1
2
3 HPI: 6 months of weakness and parathesias- originally in both feet x 2-3 months, then resolved. Now with parathesias and weakness in fingers x 1 week. Seen by podiatrist and given custom in-soles 1 month prior to presentation, difficulty maintaining balance PMH: No medications; Immunizations UTD No hospitalizations or surgeries Speech Delay Birth Hx: 24 WGA, NICU x6 months Fam Hx: Negative, Brother- healthy
4
5 Strength 3/5 LUE, deltoid and wrist ext 4/5 LUE, slight drift with LUE Reflexes: UE 2+, LE 3+ at patella bilaterally, R ankle clonus x3 beats (No clonus to L ankle), increased tone at hamstrings bilaterally c/o feeling pins and needles, decreased vibration to fingers (7 secs), absent in toes Gait: slightly wide-based
6 Which category does her presentation suggest? 6
7
8
9
10 Clinical Sign Upper Motor Neuron Lower Motor Neuron Tone Increased Decreased Reflexes Increased Decreased Weakness Present Present Babinski Present Absent Atrophy Absent* Possible Fasiculations Absent Possible *can be present due to disuse ACUTE or CHRONIC spinal cord lesions can mimic LMN disease
11 Acute Disseminated Encephalomyelitis (ADEM) Lambert Eaton Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
12 12
13 13
14 Initially flaccid, then evolves to spastic paresis with UMN signs Well-defined sensory level cervical 14
15 depends 15
16 Corticosteroids 16
17 Acute Disseminated Encephalomyelitis (ADEM) Optic Neuritis Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
18 18
19 Corticosteroids 19
20 Acute Disseminated Encephalomyelitis (ADEM) Optic Neuritis Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
21 Optic neuritis- Spinal lesion- 21
22 Anti-aquaporin-4 antibody (NMO-IgG) steroids 22
23 Often misdiagnosed as multiple sclerosis 1. DOES NOT antibodies severe anti-aquaporin 4
24 Acute Disseminated Encephalomyelitis (ADEM) Optic Neuritis Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
25 encephalopathy 25
26 asymmetric rule out infection 26
27 Corticosteroids
28 Acute Disseminated Encephalomyelitis (ADEM) Optic Neuritis Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
29 29
30 Clinically Isolated Syndrome-
31 nonencephalopathic, clinical CNS events with presumed inflammatory cause, separated by more than 30 days and involving more than one area 2. One nonencephalopathic episode typical of MS associated with MRI findings and a f/u MRI showing at least one new lesion consistent with criteria
32 periventricular Margins better defined
33 Acute attacks- Steroids Long term- Immunomodulatory agents
34 Acute Disseminated Encephalomyelitis (ADEM) Optic Neuritis Medication Side Effect Guillain Barre Syndrome (GBS) Systemic Lupus Erythematosus (SLE) Multiple Sclerosis/Clinically Isolated Syndrome Electrolyte Disorder Acute Transverse Myelitis CNS Malignancy Neuromyelitis Optica (NMO) Infectious Etiology Cerebrovascular Disease
35 peripheral nerves Most common cause of acute flaccid paralysis in infants and children* Campylobacter jejuni
36 diminished or absent reflexes
37 albuminocytologic dissociation
38 IVIG**
39 2. How will you work up and ultimately treat your patient? Specific Work-Up: MRI LP- MBP 23 (range 0-5), IgG 7.7 (range 0-6) Oligocloncal Bands 10 (range 0-1) Evoked potentials- visual testing indicates profound and diffuse slowing of conduction consistent with demyelination bilaterally. Aquaporin-4 Receptor antibody 0 (range <4) ACE level serum- 18 (low); CSF1.3 (normal)
40
41 Final Diagnosis: Multiple Sclerosis
42
Paraparesis. Differential Diagnosis. Ran brauner, Tel Aviv university
Paraparesis Differential Diagnosis Ran brauner, Tel Aviv university Definition Loss of motor power to both legs Paraparesis (paraplegia) refers to partial (- paresis) or complete (-plegia) loss of voluntary
More informationNew Insights on Optic Neuritis in Young People
Cronicon OPEN ACCESS EC OPHTHALMOLOGY Case Study New Insights on Optic Neuritis in Young People Sergio Carmona 1, Sandra Barbosa 1 and Maria Laura Ortube 2 * 1 Department of Neuro-ophthalmology, Hospital
More informationCOPYRIGHT 2012 THE TRANSVERSE MYELITIS ASSOCIATION. ALL RIGHTS RESERVED
The Transverse Myelitis Association...advocating for those with acute disseminated encephalomyelitis, neuromyelitis optica, optic neuritis and transverse myelitis ACUTE DISSEMINATED ENCEPHALOMYELITIS (ADEM)
More informationSeema Sikka, MD January 18, 2014 TRANSVERSE MYELITIS: A CLINICAL OVERVIEW
Seema Sikka, MD January 18, 2014 TRANSVERSE MYELITIS: A CLINICAL OVERVIEW DISCLOSURES I have no industry relationships to disclose. I will not discuss off-label use. OBJECTIVES: TRANSVERSE MYELITIS Review
More informationHow to Think like a Neurologist Review of Exam Process and Assessment Findings
Lehigh Valley Health Network LVHN Scholarly Works Neurology Update for the Non-Neurologist 2013 Neurology Update for the Non-Neurologist Feb 20th, 5:10 PM - 5:40 PM How to Think like a Neurologist Review
More informationMRI and differential diagnosis in patients suspected of having MS
Andrea Falini Italy MRI and differential diagnosis in patients suspected of having MS IMPROVING THE PATIENT S LIFE THROUGH MEDICAL EDUCATION www.excemed.org Outline of presentation - Diagnostic criteria
More informationContents 1 Immunology for the Non-immunologist 2 Neurology for the Non-neurologist 3 Neuroimmunology for the Non-neuroimmunologist
1 Immunology for the Non-immunologist... 1 1 The Beginnings of Immunology... 1 2 The Components of the Healthy Immune Response... 2 2.1 White Blood Cells... 4 2.2 Molecules... 8 References... 13 2 Neurology
More informationMyelitis. Case 2. History. Examination. Mahtab Ghadiri
Case 2 Myelitis Mahtab Ghadiri History A 42-year-old man presented to the emergency department with altered sensation in the lower limbs and difficulty ambulating. He first noted paresthesia in his feet
More informationMRI in Differential Diagnosis. CMSC, June 2, Jill Conway, MD, MA, MSCE
MRI in Differential Diagnosis CMSC, June 2, 2016 Jill Conway, MD, MA, MSCE Director, Carolinas MS Center Clerkship Director, UNCSOM-Charlotte Campus Charlotte, NC Disclosures Speaking, consulting, and/or
More informationTitle: Recurrent myelitis after allogeneic stem cell transplantation. Report of two cases.
Author's response to reviews Title: Recurrent myelitis after allogeneic stem cell transplantation. Report of two cases. Authors: Martin Voss (Martin.Voss@kgu.de) Felix Bischof (Felix.Bischof@uni-tuebingen.de)
More informationTHE NATURAL HISTORY OF MS: DIAGNOSIS, CLINICAL COURSE, AND EPIDEMIOLOGY
THE NATURAL HISTORY OF MS: DIAGNOSIS, CLINICAL COURSE, AND EPIDEMIOLOGY John R. Rinker II, MD University of Alabama at Birmingham Birmingham VA Medical Center May 29, 2014 DISCLOSURES Salary/Research:
More informationHigh Yield Neurological Examination
High Yield Neurological Examination Vanja Douglas, MD Sara & Evan Williams Foundation Endowed Neurohospitalist Chair Director, Neurohospitalist Division Associate Professor of Clinical Neurology UCSF Department
More informationMYELITIS. A Mochan Neurology
MYELITIS A Mochan Neurology ATM MS LETM NMOSD ATM LETM MS NMOSD Acute Transverse Myelitis Longitudinally Extensive Transverse Myelitis Multiple Sclerosis Neuromyelitis Optica Spectrum Disorders ATM ADEM
More informationPediatric acute demyelinating encephalomyelitis in Denmark: a nationwide population-based study
Pediatric acute demyelinating encephalomyelitis in Denmark: a nationwide population-based study Magnus Spangsberg Boesen November, 2016 Supervisors: P. Born, P. Uldall, M. Blinkenberg, M. Magyari, F. Sellebjerg
More informationInfection-Associated Neurological Syndromes
Infection-Associated Neurological Syndromes Anand P, MD PhD Medical Director, BloodCenter of Wisconsin Assistant Professor, Medical College of Wisconsin ASFA Annual Meeting San Antonio, TX, May 8th, 2015
More informationActualização no diagnóstico e tratamento das doenças desmielinizantes na infância. Silvia Tenembaum
Actualização no diagnóstico e tratamento das doenças desmielinizantes na infância Silvia Tenembaum Acquired CNS inflammatory/demyelinating disorders: Background information More frequent in children than
More informationPatologie infiammatorie encefaliche e midollari
Patologie infiammatorie encefaliche e midollari Maria Laura Stromillo Department of Medicine, Surgery and Neuroscience Inflammatory disorders of the CNS NMOSD ADEM Multiple Sclerosis Neuro-Myelitis Optica
More informationThe Neurologic Examination: High-Yield Strategies
The Neurologic Examination: High-Yield Strategies S. Andrew Josephson, MD Examination Approach Two types of neurologic examinations 1. Screening Examination 2. Testing Hypotheses Select high-yield tests
More informationInteractive Cases: Demyelinating Diseases and Mimics. Disclosures. Case 1 25 yo F with nystagmus; look for tumor 4/14/2017
Interactive Cases: Demyelinating Diseases and Mimics Disclosures None Brad Wright, MD 27 March 2017 Case 1 25 yo F with nystagmus; look for tumor What do you suspect? A. Demyelinating disease B. Malignancy
More informationCase presentation. Frini Karaolidou Florentia Savva Demetra Tourva Trainees in Internal Medicine, General Hospital of Limassol, Cyprus
Case presentation Frini Karaolidou Florentia Savva Demetra Tourva Trainees in Internal Medicine, General Hospital of Limassol, Cyprus Presenting complaint 45-year-old woman presenting to A&E 3 day history
More informationHeterogeneity of Demyelinating Disease: Definitions and Overlap Overview
Heterogeneity of Demyelinating Disease: Definitions and Overlap Overview Brian Weinshenker, MD, FRCP(C) Disclosures Royalties related to patent for discovery of NMO-IgG licensed to RSR Ltd; Oxford University
More information5.1 Alex.
5.1 Alex http://tinyurl.com/neuromakessense Alex is a 20-year-old full-time national serviceman. His only past medical history is asthma, presents to A&E with a 4-day history of bilateral finger weakness
More informationRSR RSR RSR RSR RSR. ElisaRSR AQP4 Ab RSR. Aquaporin-4 Autoantibody Assay Kit
To aid diagnosis of Neuromyelitis Optica (NMO) and NMO spectrum disorder (NMOSD) To confirm diagnosis before initial treatment of patients with demyelinating inflammatory disease NMO, NMOSD and AQP4 Elisa
More informationClinical Case Study Discussion of Demyelinating Diseases. Mirela Cerghet, MD, PhD Henry Ford Hospital August 6, 2011
Clinical Case Study Discussion of Demyelinating Diseases Mirela Cerghet, MD, PhD Henry Ford Hospital August 6, 2011 No financial disclosures Will discuss use of non-fda approved medication CONTENT Case
More informationMagnetic Resonance Imaging of Neuromyelitis Optica (Devic s Syndrome)
J Radiol Sci 2012; 37: 45-50 Magnetic Resonance Imaging of Neuromyelitis Optica (Devic s Syndrome) Chien-Chuan Huang Tai-Yuan Chen Tai-Ching Wu Yu-Kun Tsui Te-Chang Wu Wen-Sheng Tzeng Chien-Jen Lin Department
More information1st interactive course in MS advanced managment
6-7 December - Toronto, Canada 1st interactive course in MS advanced managment IMPROVING THE PATIENT S LIFE THROUGH MEDICAL EDUCATION www.excemed.org Liesly Lee Sunnybrook Health Sciences Centre. Department
More informationDisease of Myelin. Reid R. Heffner, MD Distinguished Teaching Professor Emeritus Department of Pathology and Anatomy January 9, 2019
Disease of Myelin Reid R. Heffner, MD Distinguished Teaching Professor Emeritus Department of Pathology and Anatomy January 9, 2019 1 I HAVE NO CONFLICTS OF INTEREST OR DISCLOSURES TO DECLARE. I HAVE NO
More informationWingerchuk et al, Neurol, 2006
Current Understanding of Neuromyelitis Optica Jacqueline A. Leavitt, M.D. Mayo Clinic Rochester, MN I have no financial disclosures 46 y/o F Pain in R temple worse with head movements, resolved in days
More informationA Hypothesis Driven Approach to the Neurological Exam
A Hypothesis Driven Approach to the Neurological Exam Vanja Douglas, MD Assistant Clinical Professor UCSF Department of Neurology Disclosures None 1 Purpose of Neuro Exam Screen asymptomatic patients Screen
More informationNeuromyelitis optica (NMO), or Devic s disease, is a rare
Case Report Neuromyelitis Optica (NMO) Abstract NMO is a is a rare entity which involves the central nervous system acting as an inflammatory process by attacking the optic nerve (ON) and longitudinally
More informationDifficult Diagnosis: Case History. 7 months prior, she happened to have undergone a C-spine MRI after a car accident
Relevant Disclosures: None Difficult Diagnosis: Recent Advances in Neurology 2013 Jeffrey M. Gelfand, MD Assistant Professor UCSF Neuroinflammation and MS Center UCSF Department of Neurology Case History
More informationPRIMARY DISEASES OF MYELIN. By: Shifaa Al Qa qa
PRIMARY DISEASES OF MYELIN By: Shifaa Al Qa qa Most diseases of myelin are primarily white matter disorders??? Myelinated axons most diseases of CNS myelin do not involve the peripheral nerves to any significant
More informationPeripheral neuropathies, neuromuscular junction disorders, & CNS myelin diseases
Peripheral neuropathies, neuromuscular junction disorders, & CNS myelin diseases Peripheral neuropathies according to which part affected Axonal Demyelinating with axonal sparing Many times: mixed features
More informationA comparison of two patients with Guillain-Barre Syndrome J O H N C O R S I N O, S P T
A comparison of two patients with Guillain-Barre Syndrome J O H N C O R S I N O, S P T Guillain-Barre Acute inflammatory demyelinating polyneuropathy Highly diverse presentation, course, outcome Miller-Fisher:
More informationThe High-Yield Neurologic Examination
The High-Yield Neurologic Examination S. Andrew Josephson MD Carmen Castro Franceschi and Gladyne K. Mitchell Neurohospitalist Distinguished Professor Chair, Department of Neurology Director, Neurohospitalist
More informationMRI Imaging of Neuromyelitis Optica
July 2009 MRI Imaging of Neuromyelitis Optica Jenna Nolan, Harvard Medical School Year III Gillian Lieberman, MD Our Patient: Initial Presentation J.H. is a 29 year-old woman who presents with acute vision
More informationAutologous Hematopoietic Stem Cell Transplantation for the Treatment of Neuromyelitis Optica in Singapore
Case Reports 26 Autologous Hematopoietic Stem Cell Transplantation for the Treatment of Neuromyelitis Optica in Singapore Koh Yeow Hoay, Pavanni Ratnagopal Abstract Introduction: Neuromyelitis optica (NMO)
More informationA CASE OF QUADRIPARE SIS. Dr Shivam Sharma Department of Medicine
A CASE OF QUADRIPARE SIS Dr Shivam Sharma Department of Medicine Clinical History A 27 yr male, shopkeeper by occupation presented with chief complaints of High grade fever with chills - 3 days Weakness
More informationBrainstorming the Case: An unusual presentation of autoimmune encephalitis
Brainstorming the Case: An unusual presentation of autoimmune encephalitis Alyssa Tilly, MD, LeeAnne Flygt, MD, MA, Ashley Sutton, MD UNC Chapel Hill Department of Pediatrics Disclosure of Financial Relationships
More informationYear 2 MBChB Clinical Skills Session Examination of the Motor System
Year 2 MBChB Clinical Skills Session Examination of the Motor System Reviewed & ratified by: o o o o Dr D Smith Consultant Neurologist Dr R Davies Consultant Neurologist Dr B Michael Neurology Clinical
More informationDone By: manar aljebreen Abdulrahman alsharidah
Female Side Male side Done By: manar aljebreen Abdulrahman alsharidah Revised By: Nour Al-Khawajah Mohammed Asiri 2 Slide No.( 1 ) Slide No.( 2 ) 3 Slide No.( 3 ) Slide No.( 4 ) Upper motor neurons are
More informationSpine Pain Management Program
Spine Pain Management Program Please complete the following information: Patient Name: Patient ID Number: Patient DOB: The procedure being requested is: Please check the indication (reason) for this procedure
More informationGuillain-Barré Syndrome
Guillain-Barré Syndrome Ouch! www.philippelefevre.com Guillain-Barré Syndrome Acute post-infective polyneuropathy Heterogeneous condition with several variant forms Lipid A Neuronal Ganglioside Pathogenesis
More informationTransverse Myelitis and Myelopathy in the VA system: Etiology and Epidemiology
Transverse Myelitis and Myelopathy in the VA system: Etiology and Epidemiology Stacey L. Clardy MD PhD Staff Neurologist, Salt Lake City VA Assistant Professor of Neurology, University of Utah Director,
More informationMyelitis. Myelitis. Multiple Sclerosis (MS) Acute demyelinating syndrome (ADS) Indictions for spinal cord MRI in MS.
Myelitis Myelitis Majda M Thurnher Professor of Radiology Medical University of Vienna University Hospital Vienna Department of Biomedical Imaging and Image-Guided Therapy Vienna Austria Acute demyelinating
More informationSupplementary Online Content
Supplementary Online Content Stevens O, Claeys KG, Poesen K, Veroniek S, Van Damme P. Diagnostic challenges and clinical characteristics of hepatitis E virus associated Guillain- Barré syndrome. JAMA Neurol.
More informationReferences 1. Feng S et al. Journal of Thoracic Oncology 2017; 12: Spain L et al. Annals of Oncology 2017; 28:
Maulik Shah, MD February 15, 2019 Patient Presentation: Progressive Sensory Disturbance In early 2018, this 57 year old man was sent to the Emergency Department after complaining in the oncology clinic
More informationDemyelinating Diseases: Multiple Sclerosis January 10, 2018 Dr. Ostrow
Demyelinating Diseases: Multiple Sclerosis January 10, 2018 Dr. Ostrow Reading: Robbins & Cotran, 9 th edition, pp 1283-1286 Robbins Basic Pathology, 9 th edition, 832-835 Overview: Grossly, myelin is
More informationDemyelinating disorder of the central nervous system occurring in black South Africans
500 J Neurol Neurosurg Psychiatry 2001;70:500 505 Demyelinating disorder of the central nervous system occurring in black South Africans G Modi, A Mochan, M Modi, D SaVer Neurology Unit, Department of
More informationDemyelinating disorder of the central nervous system occurring in black South Africans
500 Neurology Unit, Department of Medicine, Chris Hani Baragwanath Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa G Modi A Mochan DSaVer Department of
More informationLumbosacral plexus lesion Lumbosacral plexus disorders G54.1 Neuralgic amyotrophy Neuralgic amyotrophy G
ICD-9-CM and ICD-10-CM NEUROMUSCULAR DIAGNOSIS CODES Focal Neuropathy ICD-9-CM ICD-10-CM Mononeuropathy G56.00 Carpal tunnel syndrome 354.00 Other median nerve lesion 354.10 Lesion of ulnar nerve 354.20
More informationUnraveling the Mystery of MS Differential Diagnosis
Unraveling the Mystery of MS Differential Diagnosis Aliza Ben-Zacharia, ANP Ann Marie Rooney-Crino, ANP The Corinne Goldsmith Dickinson Center for Multiple Sclerosis The Mount Sinai Medical Center MS or
More informationMultiple sclerosis. Tünde Csépány MD. PhD
Multiple sclerosis Tünde Csépány MD. PhD. 11. 19. 2008. Multiple Sclerosis Approximately 350 000 people in the United States are affected by MS Prevalence strongly dependent on latitude (25-224/100 000
More informationA RARE NEUROLOGICAL PRESENTATION OF SLE. Dr Yoganand M N Dr Prithvi P Nayak
A RARE NEUROLOGICAL PRESENTATION OF SLE Dr Jayachandra Dr Yoganand M N Dr Prithvi P Nayak Presenter: Dr Shambhavi K R CHIEF COMPLAINTS A 30 year old lady hailing from Nepal presented to OPD with complaints
More informationCentral nervous system
Central nervous system By Dr. Mohsen Dashti Clinical Medicine & Pathology 316 7 th Lecture Lecture outline Review of structure & function. Symptoms, signs & tests. Specific diseases. Review of structure
More informationTECFIDERA (dimethyl fumarate) oral capsule
TECFIDERA (dimethyl fumarate) oral capsule Coverage for services, procedures, medical devices and drugs are dependent upon benefit eligibility as outlined in the member's specific benefit plan. This Pharmacy
More informationDemyelinating Diseases of the Brain
Department of Radiology University of California San Diego Demyelinating Diseases of the Brain John R. Hesselink, M.D. T1-Weighted Images Normal White Matter Contents Axons with envelope of myelin Neuroglia
More informationTHE NATURAL HISTORY OF MS: DIAGNOSIS, CLINICAL COURSE, AND EPIDEMIOLOGY
THE NATURAL HISTORY OF MS: DIAGNOSIS, CLINICAL COURSE, AND EPIDEMIOLOGY John R. Rinker, II, MD University of Alabama at Birmingham June 2, 2016 DISCLOSURES Research Support: Biogen Idec; Department of
More informationSpine Pain Management Program
Spine Pain Management Program Please complete the following information: Patient Name: Patient ID Number: Patient DOB: The procedure being requested: Facet Injection Please check the indication (reason)
More informationNeuroimmunology testing services
Neuroimmunology testing services Neuroimmunology Quest Diagnostics is your source for neuroimmunological testing with expanded offerings for several autoimmune neurological disorders Neuroimmunology is
More informationAUBAGIO (teriflunomide) oral tablet
AUBAGIO (teriflunomide) oral tablet Coverage for services, procedures, medical devices and drugs are dependent upon benefit eligibility as outlined in the member's specific benefit plan. This Pharmacy
More informationCIDP + MMN - how to diagnose and treat. Dr Hadi Manji
CIDP + MMN - how to diagnose and treat Dr Hadi Manji Outline Introduction CIDP Diagnosis Clinical features MRI Nerve conduction tests Lumbar puncture Nerve biopsy Treatment IV Ig Steroids Plasma Exchnage
More informationMultiple sclerosis mimics: Diagnostic error and management decisions
Multiple sclerosis mimics: Diagnostic error and management decisions John R Rinker, II, MD Mitchell Wallin, MD Paralyzed Veterans Summit, Washington Harbor, MD August 30, 2017 Disclosures Dr. Rinker and
More informationResearch Article Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese Multiple Sclerosis
International Scholarly Research Network ISRN Neurology Volume 211, Article ID 9476, 4 pages doi:1.542/211/9476 Research Article Optic Nerve and Spinal Cord Are the Major Lesions in Each Relapse of Japanese
More informationAdv Pathophysiology Unit 2: Neuro Page 1 of 8
Adv Pathophysiology Unit 2: Neuro Page 1 of 8 Learning Objectives for this file: 1. Amaurosis fugax presentation & DDX 2. Clinical diagnostics 3. Case study & followup Adv Pathophysiology Unit 2: Neuro
More informationNeurological Assessment for Multiple Sclerosis and Extended Disability Scale Score
Neurological Assessment for Multiple Sclerosis and Extended Disability Scale Score This section should only be completed by a neurologist or MD / ROD (Medical Doctor / Resident on Duty) involved in the
More informationCase #1: A Difficult Diagnosis
Managing Common Neurologic Inpatient Problems S. Andrew Josephson MD Carmen Castro Franceschi and Gladyne K. Mitchell Neurohospitalist Distinguished Professor Chair, Department of Neurology Director, Neurohospitalist
More informationContinuum (Minneap Minn) 2013;19(4):
Review Article Address correspondence to Dr Brian G. Weinshenker, Department of Neurology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, weinb@mayo.edu. Relationship Disclosure: Dr Wingerchuk receives
More informationSpine Pain Management Program
Spine Pain Management Program Please complete the following information: Patient Name: Patient ID Number: Patient DOB: The procedure being requested: Epidural Injection Please check the indication (reason)
More informationDaniel J. Blizzard, MD, MS
Daniel J. Blizzard, MD, MS None Common degenerative (usually) condition caused by compression on the spinal cord that is characterized by clumsiness and difficulty with fine motor tasks in the hands and
More informationInterQual Level of Care 2018 Index
InterQual Level of Care 2018 Index Rehabilitation Criteria Index Words by Subset The Index is an alphabetical listing of conditions and/or diagnoses designed to guide the user to the criteria subset where
More informationRole of MRI in acute disseminated encephalomyelitis
Original Research Article Role of MRI in acute disseminated encephalomyelitis Shashvat Modiya 1*, Jayesh Shah 2, C. Raychaudhuri 3 1 1 st year resident, 2 Associate Professor, 3 HOD and Professor Department
More informationNeuroimmunology testing services
Neuroimmunology testing services Neuroimmunology Quest Diagnostics is your source for neuroimmunological testing with expanded offerings for several autoimmune neurological disorders Neuroimmunology is
More informationRoadmap to Pediatric Demyelination: Clinical Features. Teri Schreiner, MD MPH June 1, 2014 CMSC. Disclosures
Roadmap to Pediatric Demyelination: Clinical Features Teri Schreiner, MD MPH June 1, 2014 Sunday, June 08, 2014 CMSC 1 Disclosures I participate in clinical research funded by Biogen, Teva, Novartis, NIH/NINDS,
More informationUpper and Lower Motoneurons for the Head Objectives
Upper and Lower Motoneurons for the Head Objectives Know the locations of cranial nerve motor nuclei Describe the effects of motor cranial nerve lesions Describe how the corticobulbar tract innervates
More informationTEXAS IMMUNIZATION CONFERENCE 2017 ACUTE FLACCID MYELITIS IN TEXAS
TEXAS IMMUNIZATION CONFERENCE 2017 ACUTE FLACCID MYELITIS IN TEXAS Dr. Donald Murphey Dell Children s Medical Center, Dell Medical School, Austin, Texas Pediatric Infectious Diseases November 28, 2017
More informationSalintip Kunadison MD, Chaiwiwat Tungkasereerak MD, Surin Saetang MD, Pawut Mekawichai MD
Neurology Asia 2018; 23(1) : 55 59 Comparison of clinical features between aquaporin-4 antibody seropositive and seronegative patients in neuromyelitis optica and neuromyelitis optica spectrum disorder
More informationSUSPECTED MECHANISMS INVOLVED IN MS AND PUTATIVE INTERACTIONS WITH HEPATITIS B VACCINE IN MS
SUSPECTED MECHANISMS INVOLVED IN MS AND PUTATIVE INTERACTIONS WITH HEPATITIS B VACCINE IN MS Emmanuelle Waubant, M.D. Olaf Stüve, M.D., PhD UCSF MS Center, San Francisco March 11, 2002 EPIDEMIOLOGY OF
More informationMULTIPLE SCLEROSIS PROFILE
MULTIPLE SCLEROSIS PROFILE What is Multiple Sclerosis? Multiple sclerosis (MS) is a chronic, inflammatory disease of unknown etiology that involves an immune-mediated attack on the central nervous system
More informationIdiopathic Inflammatory Demyelinating Diseases of the Brainstem
Idiopathic Inflammatory Demyelinating Diseases of the Brainstem 1 A. Rovira-Cañellas, 2 A. Rovira-Gols, 1 J. Sastre-Garriga, 1 C. Auger, 1 J. Munuera, 1 X. Montalban 1 Hospital Vall d Hebron, Barcelona.
More informationThe Neurologic Examination: High-Yield Strategies
The Neurologic Examination: High-Yield Strategies S. Andrew Josephson, MD Assistant Professor, Department of Neurology Divisions of Neurovascular and Behavioral Neurology University of California San Francisco
More informationGILENYA (fingolimod) oral capsule
GILENYA (fingolimod) oral capsule Coverage for services, procedures, medical devices and drugs are dependent upon benefit eligibility as outlined in the member's specific benefit plan. This Pharmacy Coverage
More informationAcute bilateral vision deficit as the initial symptom in Guillain Barre syndrome: A case report
EXPERIMENTAL AND THERAPEUTIC MEDICINE Acute bilateral vision deficit as the initial symptom in Guillain Barre syndrome: A case report HUI JUN WEN Department of Neurology, Baoji Municipal Central Hospital,
More information3) Approach to Ataxia - Dr. Zana
3) Approach to Ataxia - Dr. Zana Introduction Ataxia is derived from Greek word a -not, taxis -orderly, (not orderly/ not in order) Ataxia is the inability to make smooth, accurate and coordinated movements
More informationMycoplasma Pneumoniae Infection with Neurologic Complications
Case Report Iran J Pediatr Oct 2014; Vol 24 (No 5), Pp: 647-651 Mycoplasma Pneumoniae Infection with Neurologic Complications Sevgi Yimenicioğlu* 1, MD; Ayten Yakut 1, MD; Arzu Ekici 1, MD; Kursat Bora
More informationThe Deconstructed Neurological Examination
The Deconstructed Neurological Examination Marguerite Knipe, DVM, Diplomate ACVIM (Neurology) I. MENTATION: Normal, Quiet, Obtunded (mild, moderate, severe), Stuporous, Comatose Define stuporous and comatose.
More informationDISORDERS OF THE MOTOR SYSTEM. Jeanette J. Norden, Ph.D. Professor Emerita Vanderbilt University School of Medicine
DISORDERS OF THE MOTOR SYSTEM Jeanette J. Norden, Ph.D. Professor Emerita Vanderbilt University School of Medicine THE MOTOR SYSTEM To understand disorders of the motor system, we need to review how a
More information2014 FLORIDA FOR THE TMA
Dear Corporate Sponsor, Celebrity and Supporter: We are proud to announce that we are hosting the 2nd Annual Central Florida Auction and Walk on December 12-13, 2014 in honor of our daughter Sarah Robbins
More informationBrain and Central Nervous System Cancers
Brain and Central Nervous System Cancers NICE guidance link: https://www.nice.org.uk/guidance/ta121 Clinical presentation of brain tumours History and Examination Consider immediate referral Management
More informationNeuromyelitis optica mimics the morphology of spinal cord tumors
The Turkish Journal of Pediatrics 2016; 58: 309-314 Case Report Neuromyelitis optica mimics the morphology of spinal cord tumors İlknur Erol 1, Murat Özkale 2, Tülin Savaş 1, Özlem Alkan 3, Melih Çekinmez
More informationInternational IBD Genetics Consortium
International IBD Genetics Consortium PRED4 Case Report Form Please stick study label here On completion, please return to: Claire Bewshea IBD Pharmacogenetics Research Office Ground Floor, Child Health
More informationFaculty Disclosure. Sanjay P. Singh, MD, FAAN. Dr. Singh has listed an affiliation with: Consultant Sun Pharma Speaker s Bureau Lundbeck, Sunovion
Faculty Disclosure Sanjay P. Singh, MD, FAAN Dr. Singh has listed an affiliation with: Consultant Sun Pharma Speaker s Bureau Lundbeck, Sunovion however, no conflict of interest exists for this conference.
More informationAcute flaccid paralysis: An approach to diagnosis
Case Report Yadav et.al. : An approach to diagnosis AK Yadav, P Bhattarai, B Aryal, PP Gupta, S Chaudhari, A Yadav Department of General Practice and Emergency Medicine B.P. Koirala Institute of Health
More informationNIH Public Access Author Manuscript J Neurol Sci. Author manuscript; available in PMC 2010 February 24.
NIH Public Access Author Manuscript Published in final edited form as: J Neurol Sci. 2009 January 15; 276(1-2): 196 198. doi:10.1016/j.jns.2008.09.025. Recurrent varicella zoster virus myelopathy Don Gilden
More informationSpine Pain Management Program
Spine Pain Management Program Please complete the following information: Patient Name: Patient ID Number: Patient DOB: The procedure being requested: Epidural Adhesiolysis Please check the indication (reason)
More informationMULTIPLE SCLEROSIS Update
MULTIPLE SCLEROSIS Update E. Torage Shivapour, M.D. Clinical Professor Department of Neurology University of Iowa Hospitals & Clinics Disclosures I do not have any disclosures. Multiple Sclerosis Most
More informationDemyelinating and Immunologic Disorders
Demyelinating and Immunologic Disorders Nicholas Johnson, MD University of Utah Salt Lake City, Utah The nervous system may be affected by a number of autoimmune conditions. The most common of these conditions
More informationThe Diagnosis Of Multiple Sclerosis DR SAHER HASHEM PROF OF NEUROLOGY CAIRO UNIVERSITY
The Diagnosis Of Multiple Sclerosis DR SAHER HASHEM PROF OF NEUROLOGY CAIRO UNIVERSITY There is no path gnomonic or perfect laboratory test which may be used in isolation to reliably diagnose MS. The key
More informationORIGINAL CONTRIBUTION. of patients with idiopathic progressive
Progressive Necrotic Myelopathy Clinical Course in 9 Patients Joshua D. Katz, MD; Allan H. Ropper, MD ORIGINAL CONTRIBUTION Objective: To review the clinical, laboratory, and radiological findings of 9
More information