pre-laser cut pre-laser cut Pre-operative Known and Potential Complications of SMILE Failure to obtain an adequate suction
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1 pre-laser cut! Known and Potential Complications of SMILE Failure to obtain an adequate suction Walter Sekundo Correct treatment pack size (S in myopic cases) Philipps University Marburg/Germany Use speculum with suction VisuMax internal settings o.k.? (Hotline) The author have no financial interest in any topics related to this study. Prof. Sekundo is a member of the scientific board of Carl Zeiss Meditec AG 2 Pre-operative pre-laser cut Decentration (mm) from pupil centre 4 Centration: minor nasalisation is normal (angle κ) ReLEx Fs-Lasik OD, OS 3 *Lazaridis & Sekundo, JRS OD, OS Decentration (mm) from corneal apex ,2 0,2-0 0,- 32 > Purkinje projection (obeservation mode) Apply suction after 8-0% applanation Do not apply suction > 3 times ReLEx Mean Decentration: 0.326mm 20 st Watch the Nasalisation of the fixation in relation to the pupil centre = positive angle κ 2 0,2-0 0,- Centration is randomly distributed Control of cyclorotation is a problem unless adjusted manualy by Contact Glass rotation 0 0-0,2 fs-lasik Mean Decentration: 0.42mm > 3 *Lazaridis & Sekundo, JRS 204 4
2 Suction loss: 3.2%* During laser cut VisuMax software assists you in decision making:.convert to ReLEx FLEx or continue with SMILE with a larger cap, if the bottom plane Hinge width has been accomplished Suction loss intermittend laser stop (fluid in interface) 2. Abort procedure, if suction loss occurred during the first cut: perform microkeratome Lasik or PRK with MMC or phakic IOL later Poor dissection Incomplete cut (e.g. incomplete sidecut) 3. A vertical opening cut is possible at any time ) Lamellar ring 2) Overlap 3) Side Cut with Hinge 4. Software flap making tool can be used later in time * Wong CW et al, JCRS Microstriae after SMILE? Dissection ReLEx SMILE does not induce any microstriae in the cap when examined by slitlamp, unless stained with fluorescein (D. Reinstein) Manual stretching + ironing toward the periphery at the conclusion of procedure helps Epithelial slugh off (basement membrane dystrophy): Contact lens, steroids (DLK!) Cap perforation & tear: I usually use >20µm cap, adapt and leave: usually heals well Coutesy of R.Shah tear Bowman s Layer Microdistorsions (BLMD) Tear at the incision site for SMILE: usually not a big problem I can be detected by OCT after SMILE correlate with the extent of Incomplete side cut: always keep a micro-blade in the OR correction* BLMD do not produce visual Wrong plane : - use hook movement from anterior lip or invert the edge (incisions >3.mm) - separate from distal end with Mehta reversed dissector* BLMD Grade 0 symptoms in the mid-term BLMD Grade 2 *Liu Y-C, Pujara T, Mehta JS, PLOS One * Messerschmidt-Roth & Sekundo 203 8
3 Post-op Epithelial ingrowth. Epithelial plug 2. Lenticule "left-overs" and debris in the interface 3. DLK Always only a plug (so far) Observe Intervene only if progressive Put a stich 4. Haze" in the interface. Ectasia 6. Infection 7. Unusual cases Lenticule remains Debris Very serious complication, if Usually at the edge Do not affect vision Consider a longer course of steroids to prevent local inflammation Within optical zone (more prone in hyperopic treatments) Usually at the edge in myopic treatment Irregular astigmatism Central island in hyperopia treatment (experimental) Dissect from the middle toward the periphery, respect counter-action Use curved dissector Use forceps only after complete dissection 2
4 Haze/DLK Decentration DLK Incidence.6%* Decentration (has been discussed above): never saw clinical significance. Otherwise topography guided excimer ablation (Ivarsen et al.) erosion at the opening incision thin lenticules 0µm Use steroids vigorously Haze After DLK As primary scarring Usually does not affect vision Consider a longer course of steroids (e.g. FML) after difficult dissection My worst case *Zhao J et al, JCRS 20 3 Ectasia 4 Infection/unusual cases Infection: no reports in the literature, but probably not very different from fs-lasik *Simultaneous uneventful SMILE for -6D True ectasia: only one case reported after FLEx (Blum M. et al). Misdiagnosed form fruste Keratoconus: CXL done Post-op UDVA OD=0.8 OS=.4 Ectasia secondary to forceful dissection ( via falsa ): RGP, DALK, if CL intolerance Deterioration of vision OD Unchanged OS * Courtesy of K. Shimizu, Kitasato University/Japan
5 3/2 post-op 2/2 after re-intervention Edema and interface fluid collection Courtesy Prof Shimizu Residual edema and interface fluid collection Courtesy Prof Shimizu CDVA=0.4 (-3.7 cyl Ax) IOP =.7 mmhg, IOPcc = 27 mmhg CDVA=0. (-3.7 cyl Ax ) IOP =.0 mmhg, IOPcc = 20. mmhg DDx: ) Pressure induced interlamellar keratitis 2) low grade infection 2/2 after ) Pocket irrigation 2) Steroids discontinued 2) IOP lowering medication Shimizu, Kitasato University/Japan Conclusion Despite its novelty, complications after SMILE are rare, even with new users In the vast majority they are similar to fs-lasik and can be addressed accordingly However, SMILE requires more manual work and has a steep learning curve Surgeons novel to this technique should stick to the suggested training protocol Shimizu, Kitasato University/Japan
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