Hands on workshops. 08:00-10:15 Session 1 - LAA morphology and imaging Moderator: Saibal Kar, MD / Shakeel A. Qureshi, MD / Bushra Rana, MD

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1 Friday, November 20th, :00-18:30 Registration 07:00-08:00 Welcome coffee Hands on workshops 08:00-10:15 Session 1 - LAA morphology and imaging Moderator: Saibal Kar, MD / Shakeel A. Qureshi, MD / Bushra Rana, MD TEE before and during LAA closure: case based lecture Bushra Rana, MD 3D TEE sizing of the ostium and matching device size by area Martin W. Bergmann, MD LAAC imaging implantation of a Watchman with a micro-tee Martin Swaans, MD Intraprocedural angiography without echo Fabian Nietlispach, MD Rotational angiography: one step forward Tom De Potter, MD TEE Follow-up: thrombus and residual leak Bushra Rana, MD ICE guidance during LAA closure Jens Erik Nielsen-Kudsk, MD CT before and after LAA closure Sergio Berti, MD CT image analysis using Osirix Apostolos Tzikas, MD CT image analysis using 3mensio Mark Spence, MD Echonavigator Sameer Gafoor, MD 10:15-10:45 Coffee & tea break 10:45-11:45 Session 2 - LAA closure with the LAmbre occluder Moderator: Jai-Wun Park, MD / Yat-Yin Lam, MD Device design and anatomical inclusion/exclusion criteria and LAmbre EU clinical trial results

2 Jai-Wun Park, MD LAmbre step by step and advances tips and tricks Yat-Yin Lam, MD Case presentations and LAmbre China clinical trial results He Huang, MD 11:45-13:00 Session 3 - LAA closure with the Watchman Occluder Moderator: Saibal Kar, MD / David Foley, MD / Matthew Price, MD Device design and anatomical inclusion/exclusion criteria Saibal Kar, MD Watchman step by step and advances tips and tricks Martin W. Bergmann, MD Case examples Peter Sick, MD Case examples with Watchman Flx Horst Sievert, MD 13:00-14:00 Lunch session - Abstracts Moderator: Stefan Bertog, MD / Simon Lam, MD / Sameer Gafoor, MD Rationale of cerebral protection devices in left atrial appendage occlusion Felix Meincke, MD Cross-sectional computed tomographic superior to 2D and 3D TEE for LAA characterization of size and therefore device selection Dee Dee Wang, MD Deliverability, conformability and healing response of Watchman FLX LAAC device Elena Ladich, MD A comparison of 2-D and 3-D echocardiography imaging during percutaneous left atrial appendage closure (LAAO) Katarzyna Mitrega, MD A comparison of procedural and short-term clinical outcomes of left atrial appendage occlusion between Amplatzer cardiac plug and Watchman device in patients with non-valvular atrial fibrillation: from korean multicenter registry Seung Hun Lee, MD 14:00-15:00 Session 4 - LAA occlusion with the new Amulet Moderator: Kevin P. Walsh, MD / Fabian Nietlispach, MD Device design and anatomical inclusion/exclusion criteria Apostolos Tzikas, MD

3 Amulet: step by step and advance tips and tricks Thorsten Lewalter, MD Interactive case examples; what do you think? KR Julian Chun, MD Case example challenging anatomy- Chicken wing Kevin P. Walsh, MD implanting Amulet using CT + ICE imaging Jens Erik Nielsen-Kudsk, MD 15:00-16:00 Session 5 - Transpericardial LAA closure with the LARIAT device Moderator: Neil Wilson, MD / / Stefan Bertog, MD Patient selection for the LARIAT procedure Abdi Rasekh, MD LARIAT step by step and recent device and technique modifications What happens to the LAA after epicardial ligation? Krzysztof Bartus, MD Post procedural management after LARIAT Abdi Rasekh, MD 16:00-16:30 Coffee & tea break 16:30-17:30 Session 6 - LAA closure with the WaveCrest Occluder Moderator: Neil Wilson, MD / Sameer Gafoor, MD Introduction of new design features of the Coherex WaveCrest LAA occlusion system Marcus Sandri, MD Recorded case KR Julian Chun, MD A challenging case with Coherex WaveCrest Martin W. Bergmann, MD Saturday, November 21st, :00-18:00 Registration 07:00-08:00 Welcome coffee

4 08:00-10:00 Session 7 - Why and when to close the LAA Moderator: Shakeel A. Qureshi, MD / Stefan Bertog, MD Embryology, anatomy and function of the LAA Piotr Suwalski, MD The rationale for LAA closure in 2015: bleeding risk, stroke risk new data Indication for LAA closure current status and future perspectives - US view Matthew Price, MD current status and future perspectives - EU view Peter Sick, MD current status and future perspectives - UK view Jan Kovac, MD Update on NOAC clinical trial data - do NOACs obviate the need for LAA Closure? Abdi Rasekh, MD My real-life experience with LAA closure how I convinced referrals and built a network Patrizio Mazzone, MD 10:00-10:30 Coffee & tea break 10:30-12:30 Session 8 - New clinical trial data A Moderator: Saibal Kar, MD / Neil Wilson, MD / Sameer Gafoor, MD Antithrombotic therapy after LAA closure: pathophysiology, clinical experience, trial results Stefan Bertog, MD The Watchman device - latest data from the randomized clinical trials Matthew Price, MD The Watchman device - latest data from real life registries Horst Sievert, MD 12:30-13:15 Lunch break

5 13:15-14:15 Session 9 - New clinical trial data B Moderator: Shakeel A. Qureshi, MD / Stefan Bertog, MD ACP and Amulet Simon Lam, MD LARIAT A comparison of leak rates with the LARIAT versus the Watchman 14:15-15:45 Session 10 - New LAA closure devices and techniques Moderator: Neil Wilson, MD / Stefan Bertog, MD / Sameer Gafoor, MD Amplatzer Amulet Kevin P. Walsh, MD Lifetech Yat-Yin Lam, MD Occlutech Jai-Wun Park, MD PROLIPSIS E.B. Sideris, MD Watchman FLX design and potential benefits of a new device Marcus Sandri, MD First clinical experience with the Watchman FLX device Saibal Kar, MD AtriClip (Atricure) Piotr Suwalski, MD Cardia Denis Haagen Acoredis Marcus Sandri, MD 15:45-16:00 Coffee & tea break 16:00-18:00 Session 11 - Challenging cases and complications Moderator: Shakeel A. Qureshi, MD / Neil Wilson, MD

6 Case 1: late follow-up Sameer Gafoor, MD Case 2: thrombus and Leak Simon Lam, MD Case : LAA closure dislodgment and bailout approach Evgeniy Merkulov, MD Closing remarks and thank you Horst Sievert, MD / Shakeel A. Qureshi, MD / Neil Wilson, MD

Scientific Program of LAA 2014

Scientific Program of LAA 2014 Friday, November 14th, 2014 08:00-18:30 Registration 08:00-08:05 Welcome 08:05-08:45 Session 1: How Morphology Affects Short- and Long-term Outcome? What you Need to Know