DAFTAR PUSTAKA. Amerongen, A.V.N., 1991, Ludah dan Kelenjar Ludah, Gadjah Mada University Press, Yogyakarta.

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1 DAFTAR PUSTAKA Ababneh, K.H., Hwaij, Z.M.F., dan Khader, Y.S., 2012, Prevalence and Risk Indicators of gingivitis and Periodontitis in a Multi-Centre Study in North Jordan: A Cross Sectional Study, BMC. Oral. Health., 12(1): Afennich, F., Slot, D.E., Hossainian, N., dan Van der Weijden, G.A., 2011, The Effect of Hexetidine Mouthwash on The Prevention of Plaque and Gingival Inflammation: A Systematic Review, Int. J. Dent. Hyg., 9(3): Aherne, S.A., Kerry, J.P., dan O Brien, N.M., 2006, Effects of Plant Extracts On Antioxidant Status and Oxidant-Induced Stress In Caco-2 Cells, Br. J. Nut., 97: Ali, A.,Khan, S.Z., Nasir, H., Ullah, I., Ullah, A., Ahmad, R., Junaid, Ali, M., Khan, S., Alvi, I.A., dan Rehman, M.U., 2014, In vitro Antibacterial Activity of Leaf Extracts of Psidium guajava Against Selected Pathogenic Bacterial Strains, Int. J. Innov. Sci. Res., 3(1): Amerongen, A.V.N., 1991, Ludah dan Kelenjar Ludah, Gadjah Mada University Press, Yogyakarta. Asif, M., dan Khodadadi, E., 2013, Medical Uses and Chemistry of Flavonoid Contents of Some Common Edible Tropical Plants, J. Paramed. Sci., 4(3): Axelsson, P., 2002, Diagnosis and Risk Prediction of Periodontal Diseases, Quintessence Publishing Co Inc, Slovakia. Aznita, W.H.H., Abidin, Z., Aznan, E., dan Razi, M.N., 2009, The Effectiveness of Chlorhexidine, and Eugenia caryophyllus Extracts in Commercialized Oral Rinses to Reduce Dental Plaque Microbes, Res. J. Biol. Sci., 4(6): Baehni, P.C., dan Takeuchi, Y., 2003, Anti-Plaque Agents in The Prevention of Biofilm Associated Oral Diseases, Oral. Dis., 9(1): Beeh, K.M., Beier, J., Haas, I.C., Kornmann, O., Micke, P., dan Buhl, R., 2002, Glutathione Deficiency of the Lower Respiratory Tract in Patients with Idiopatic Pulmonary Fibrosis, Eur. Respir. J., 19:

2 Biswas, B., Rogers, K., McLaughlin, F., Daniels, D., dan Yadav, A., 2013, Antimicrobial Activities of Leaf Extracts of Guava (Psidium guajava L.) on Two Gram-Negative and Gram-Positive Bacteria, Int. J. Microbiol., 2013: Borges, I.Jr., Moreira, E.A.M., Filho, D.W., Oliveira, T.B., Silva, M.B.S., dan Frode, T.S., 2007, Proinflammatory and Oxidative Stress Markers in Patients with Periodontal Disease, Mediators. Inflamm., 2007: Chandra, R.V., Prabhuji, V., Roopa, A., Ravirajan, S., dan Kishore, H.C., 2007, Efficacy of Lycopene in the Treatment of Gingivitis: A Randomised, Placebo- Controlled Clinical Trial, Oral. Health. Prev. Dent., 5: Chapple, I.L.C., dan Mason, G.I., 1997, Enhanced Chemiluminescent Assay for Measuring the Total Antioxidant Capacity of Serum, Saliva, and Crevicular Fluid, Ann. Clin. Biochem., 34(4): Chapple, I.L.C., Brock, G., Eftimiadi, C., dan Mattews, J.B., 2002, Glutathione in Gingival Crevicular Fluid and Its Relation to Local Antioxidant Capacity in Periodontal Health and Disease, J. Clin. Pathol., 55: Dahlan, M.S., 2013, Statistik untuk Kedokteran dan Kesehatan, 3 th Medika, Jakarta. ed, Salemba Deepa, T.N., dan Thirrunavukkarasu., 2009, Saliva As a Potential Diagnostic Tool, Indian. J. Med. Sci., 64(7): Departemen Kesehatan RI, 2001, Ilmu Penyakit Gigi Dan Mulut, Jakarta. Durgo, K., Vukovi, L., Rusak, G., dan Osmak, M., 2007, Effect of Flavonoids on Glutathione Level, Lipid Peroxidation and Cytochrome P450 CYP1A1 Expression in Human Laryngeal Carcinoma Cell Lines, Food. Technol. Biotechnol., 45(1): Edgar, M., Dawes, C., dan Mullane, D.O., 1996, Saliva and Oral Health, British Dental Association, London. Fedi, P.F., dan Vernino, A.R., 2000, Silabus Periodonti, Ed ke-4, Penerbit Buku Kedokteran EGC, Jakarta. Fridovich, I., 1997, Superoxide Anion Radical, Superoxide Dismutases, and Related Matters, J. Biol. Chem., 272: Glickman, S., 1974, Clinical, Radiographic and Histopathologic Features, W.B. Saunders, Philadelphia. 2

3 Halliwell, B., dan Gutteridge, 1999, Free Radicals in Biology and Medicine, 3 rd ed, Clarendon Press, Oxford. Han, D.H., Kim, M.J., Jun, E.J., dan Kim, J.B., 2013, The Role of Glutathione Metabolism in Cariogenic Bacterial Growth and Caries in Korean Children, Arch. Oral. Biol., 58: Hardjawinata, K., Sufiawati, I., Djustiana, N., Muchtaridi, dan Dewi, S.O., 2009, Ekstrak Daun Jambu Biji (Psidium guajava) sebagai Obat Kumur untuk Pengobatan Gingivitis pada Wanita, Ringkasan Eksekutif Penelitian, Harville, E.W., Zhang, J., dan Hatch, M.C., 2004, Oral Sex and Gum Disease, Sex. Transm. Infect., 80 : Harun, N., dan Syari, W., 2002, Aktivitas Antioksidan Ekstrak Daun Dewa dalam Menghambat Sifat Hepatotoksik Halotan dengan Dosis Sub Anestesi pada Mencit, Jurnal Sains dan Teknologi Farmasi, 7(2): He, Q., dan Venant, N., 2013, Antioxidant Power of Phytochemicals from Psidium guajava Leaf, J. Zhejiang. Univ. Sci., 5(6): Hoag, P.M., dan Pawlak, E.A. 1990, Essentials of Periodontics, 4 th ed, The CV Mosby Company, St. Louis. Hyun You, D., Park, J.W., Gyun Yuk, H., dan Cheol, L., 2011, Antioxidant and Tyrosinase Inhibitory Activities of Different Parts of Guava (Psidium guajava L.), Food. Sci. Biotechnol., 20(4): Ismail, M., Minhas, P.S., Khanum, F., Sahana, V.M., dan Sownya, 2012, Antibacterial Activity of Leaves Extract of Guava (Psidium guajava), Int. J. Res. Pharm. Biomed. Sci., 3(1): 1-8. Iwasaki, Y., Hoshi, M., Ito, R., Saito, K., dan Nakazawa, H., 2006, Analysis of Glutathione and Glutathione Disulfide in Human Saliva using Hydrophilic Interaction Chromatography with Mass Spectrometry, J. Chromatogr. B., 839: Jones, D.P., 2011, The Health Dividend of Glutathione, Nat. Med. J., 3(2). Junior, A.B., Souza, S.L.S., Taba, M., Grisi, M.F., Suzigan, L.C., dan Tunes, R.S., 2004, Control of Gingival Inflammation in a Teenager Population Using Ultrasonic Prophylaxis, Braz. Dent. J., 15(1):

4 Kapic, E., Becic, F., dan Becic, E., 2002, Hexetidine-An Oral Antiseptic, Med. Arh., 56(1): Kaur, G, Tirkey, N., Chanana, V., Pishi, P., dan Chopra, K., 2006, Inhibition of Oxidative Stress and Cytokine Activity by Curcumin in Amelioration of Endotoxin Induce Experimental Hepatoxicity in Rodents. Clin. Exp. Immunol., 145(2): Kerksick, C., dan Willoughby., 2005, The Antioxidant Role of Glutathione and N- Acetyl-Cysteine Supplements and Exercise-Induced Oxidative Stress, J. Int. Soc. Sports. Nutr., 2: Kidd, P.M., 2001, Glutathione: Systemic Protectant Against Oxidative and Free Radical Damage, Altern. Med. Rev., 2(3): Kelly, F.J., 2003, Oxidative Stress: Its Role Air Pollution and Adverse Health Effect, Occup. Environ. Med., 60(8): Lang, N.P., Schatzle, M.A., dan Löe, H., 2009, Gingivitis As a Risk Factor in Periodontal Disease, J. Clin. Periodontol., 36(Suppl. 10): 3 8. Lawrence, H.P., 2002, Salivary Markers of Systemic Disease: Noninvasive Diagnosis of Disease and Monitoring of General Health, J Can Dent Assoc, 68(3) : Lee, Y.H., dan Wong, D.T., 2009, Saliva: An Emerging Biofluid for Early Detection of Diseases, Am. J. Dent., 22( 4): 1-8. Lushchack, V.L., 2011, Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions, J. Amino. Acids., 2012: Manson, J.D., dan Eley, B.M., 2004, Periodontics, 5 th London. ed, Library of Congress, Martha, R., Mitchell, S., dan Solis, R.V., 2008, Psidium guajava: A Review of Its Traditional Uses, Phytochemistry and Pharmacology, J. Ethnopharmacol., 117:1 27. Mesah, A., 2013, Aktivitas Antioksidan Ekstrak Metanol Daun dan Buah Jambu Biji (Psidium guajava L) Asal Pulauan Timor, Jurnal Kimia Terapan, 1(1):

5 Moskaug, J., Carlsen, H., Myhrstad, M.C.W., dan Blomhoff, R., 2005, Polyphenols and Glutathione Synthesis Regulation, Am. J. Clin. Nutr., 81(suppl):277S 83S. Murray, Granner, D., Mayer, P., dan Rodwell, V., 2000, Biokimia Harper (terj.), Penerbit Buku Kedokteran EGC, Jakarta. Musa, K.H., Abdullah, A., Jusoh, K., dan Subramaniam., 2011, Antioxidant Activity of Pink-Flesh Guava (Psidium guajava L.): Effect of Extraction Techniques and Solvents, Food. Anal., 4: Newman, M.G., Takei, H.H., dan Klokkevod, P.R., 2006, Carranza s Clinical Periodontology, 10 th edition, WB Saunders, Philadelphia. Nijveldt, R.J., Nood, E., Hoorn, D.E.C., Boelens, P.G., Norren, K., dan Leeuwen, P.A.M., 2001, Flavonoids: a Review of Probable Mechanisms of Action and Potential Applications, Am. J. Clin. Nutr., 74: Notoatmodjo, 2010, Metode Penelitian Kesehatan, Rineka Cipta, Jakarta. Ozturk, L.K., Furuncuoglu, H., Ulukoylu, O., Akyuz, S., dan Yarat, A., 2008, Association Between Dental-Oral Health in Young Adults and Salivary Glutathione, Lipid Peroxidation, and Sialic Acid Levels and Carbonic Anhydrase Activity, Braz. J. Med. Biol. Res., 41(11): Parimin, S.P., 2005, Jambu Biji: Budi Daya dan Ragam Pemanfaatannya, Penebar Swadaya, Jakarta. Peng, I.W., dan Kuo, S.M., 2003, Flavonoid Structure Affects the Inhibition of Lipid Peroxidation in Caco-2 Intestinal Cells at Physiological Concentrations, J. Nutr., 133: Phuong, N.T.M., Nghia, P.T., dan Marquis, R.E., 2006, Zinc Effect on Oxidative Physiology of Oral Bacteria, Adv. Nat. Sci., 7(1.2) : Pressman, A.H., 1997, Glutathione: The Ultimate Antioxidant, St. Martin s Press, New York. Proctor, P.H., dan Reynolds, E.S., 1984, Free Radicals and Disease in Man, Physiol. Chem. Phys. Med., 16: Rai, B., 2008, Total Salivary Glutathione Levels: Periodontitis in Smoker and Non- Smoker, Adv. Med. Dent. Sci., 2(2):

6 Reeves, J., 2013, The Role of Saliva in Oral and Systemic Health, Dent. Health., 52 (5) : Sanchez, A., dan Medina, M.A., 1999, Glutamine, as A Precusor of Glutathione, and Oxidative Stress, Mol. Genet. Metab., 67(2): Sen, C.K., 1995, Oxidant dan Antioxidant in Exercise, J. Appl. Physiol., 79: Sculley, D.V., dan Evans, S.C., 2002, Salivary Antioxidants and Periodontal Disease Status, Proc. Nutr. Soc., 61: Sculley, D.V., dan Evans, S.C., 2003, Periodontal Disease is Associated with Lower Antioxidant Capacity in Whole Saliva and Evidence of Increased Protein Oxidation, Clin. Sci., 105: Sharma, A., dan Sharma, S., 2011, Reactive Oxygen Species and Antioxidants in Periodontics: A Review, Int. J. Dent. Clin., 3(2): Sharma, N.C., Galvstians, H.J., Qaqish, J., Charles, C.H., Vircent, J.W., dan Mc Guire, J.A., 2003, Antiplaque and Antigingivitis Effectiveness of a Hexetidine Mouthwash, J. Clin. Periodontol., 30(7): Shruthi, S.D., Roshan, A., Timilsina, S.S., dan Sunita, S., 2013, A Review on the Medicinal Plant Psidium guajava Linn. (Myrtaceae), J. Drug. Deliv. Ther., 3(2): Sobaniec, H., Sobaniec-Lutowska, M.E., dan Zimnoch, L, 1999, Correlation Between Morphological Changes in Gingival Tissue and Increase Concentration of Lipid Peroxides in the Course of Experimental Periodontitis in Rats. Med. Sci. Monit., 5(5): Solomon, N., dan Patricia, A., 2011, Uncommon Causes of Gingivitis, J. Dent. Oral. Hyg., 3(5): Taju, G., Jayanthi, M., dan Majeed, A., 2011, Original Article Evaluation of Hepatoprotective and Antioxidant Activity of Psidium guajava Leaf Extract Against Acetaminophen Induced Liver Injury in Rats, Int. J. Toxicol. Appl. Pharmacol., 1(2): Tenovuo, J., dan Lagerlof, F. 1994, Saliva, In: Textbook of Clinical Cariology, 2 nd ed, Thylstrup, A dan Fejerskov, O. (ed.), Munksgaard, Denmark, pp

7 Varghese, J.M., Bhat, V., Bhat, G.S., dan Rao, N., 2012, Evaluation of Glutathione- S-Transferase and Ceruloplasmin Levels in Gingival Crevicular Fluid and Gingival Tissue as Diagnostic Markers for Chronic Periodontitis, Adv. Bioscience. Biotechnol., 3: Versteeg, P.A., Rosema, N.A.M., Hoenderdos, N.L., Slot, D.E., dan Van der Weijden, G.A., 2010, The Plaque Inhibitory Effect of a CPC Mouthrinse in a 3- Day Plaque Accumulation Model a Cross-Over Study, Int. J. Dent. Hyg., 8 (4): Vyas, N., Tailang, M., Gavatia, N.P., dan Gupta, B.K., 2010, Antioxidant Potential of Psidium Guajava Linn, Int. J. Pharm. Tech. Res., 2(1): Weni, L., Harliansyah, dan Widayanti, 2011, Anti Inflammatory Activity of the Extract of Guava Leaves (Psidium guajava L) in the Rat (Rattus norvegicus L), Indo. J. Canc. Prev., 2(1): Welsh, A.L., dan Ede, M., 1958, Evaluation of the Topical Therapeutic Efficacy of Hexetidine (Sterisil) in Various Dermatoses, J. Invest. Dermatol., 30: Wojdylo, A., Oszmian ski, J., dan Czemerys, R., 2007, Antioxidant Activity and Phenolic Compounds in 32 Selected Herbs, Food. Chem., 105: Wolf, H.F., Rateitschak, K.H., dan Hassel, T.M., 2005, Color Atlas of Dental Medicine Periodontology, Thieme, New York. Wu, G., Fang, Y.Z., Yang, S., Lupton, J.R., dan Turner, N.D., 2004, Glutathione Metabolism and Its Implications for Health, J. Nutr., 134(3): Yin Chen, H., dan Chin Yen, G., 2007, Antioxidant Activity and Free Radical- Scavenging Capacity of Extracts from Guava (Psidium guajava L.) Leaves, Food. Chem., 101: Yoo, K.M., Lee, C.H., Lee, H., Moon, B.K., dan Lee, C.Y., 2007, Relative Antioxidant and Cytoprotective Activities of Common Herbs, Food. Chem., 106: Zappacosta, B., Perchili S., dan Mordente, A., 1997, Inhibition of Salivary Enzymes by Cigarette Smoke and the Protective Role Glutathione, Oncol., 33: Zheng, H., Yang, J.z., Li, C.J., dan Zhang, D.M., 2011, A New Benzophenone Glycoside from the Leaves of Psidium guajava L, Chin. Chem. Lett., 22:

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