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1 Note: Page numbers of article titles are in boldface type. A N-Acetylcysteine in endometritis management, 506 Acupuncture in endometritis management, 508 Anatomic defects correction of in persistent post-breeding endometritis management, Antibacterial agents in endometritis management, Antimicrobial agents in persistent post-breeding endometritis management, 472 Antimicrobial peptides in endometritis management, Anti-Müllerian hormone, basic aspects of, biological functions of in stallions and mares, clinical applications of, in mares, in stallions, discovery of, protein in, Anti-Müllerian hormone gene, 453 Arousal disorders inadequate in stallions diagnostic and therapeutic techniques for, Assisted reproduction techniques oocyte collection, transport, and maturation for, (See also Oocyte(s), for assisted reproduction techniques) B Bacteria in infectious endometritis diagnosis, Biofilm described, 500 Biofilm infections evaluation of patient overview in, 500 Vet Clin Equine 32 (2016) /16/$ see front matter vetequine.theclinics.com

2 562 Biomarker(s) in stallions and mares, Breeding management in persistent post-breeding endometritis management, 477 Broodmare(s) with EMS/IR medical management of, with PPID medical management of, C Centrifugation cushioned for semen from subfertile stallions, gradient for semen from subfertile stallions, of semen general guidelines for, Cervical relaxation hormone therapy in, Chelating agents in endometritis management, 506 Cloprostenol in persistent post-breeding endometritis management, 476 Cryopreservation breakthroughs in, (See also Embryo(s), freezing of) current techniques for freezing embryos, future of, 423 of stallion semen, (See also Semen, cryopreservation of) Cryptorchidism biomarker of in stallions, Cytology in infectious endometritis diagnosis, bacteria, debris, 491 fungal organisms, 494 red blood cells, 492 uterine epithelial cells, white blood cells, 492 yeasts, 494 D Debris in infectious endometritis diagnosis, 491

3 563 E Ecbolic drugs, 429 in endometritis management, in persistent post-breeding endometritis management, Embryo(s) freezing of current techniques for, future of, 423 manipulating large embryos prior to, Embryo recovery and transfer (ET) changes in horse industry related to, described, 415 EMS. See Equine metabolic syndrome (EMS) Endocrine diseases diagnostic testing for, epidemiology of, introduction, reproduction effects of, Endometritis evaluation of patient overview in, 500 infectious diagnosis of, molecular tests in, sample collection from uterus in, (See also Uterus, samples from) sample evaluation in, introduction, risk factors for, management of antibacterial agents in, ecbolic drugs in, nontraditional therapies in, N-acetylcysteine, 506 acupuncture, 508 antimicrobial peptides, chelating agents, 506 exercise, 508 hydrogen peroxide, immunomodulators, 505 introduction, kerosene, nutrition, regenerative therapies, 508 pharmacologic, uterine irrigation/lavage in, 503 persistent post-breeding diagnosis of, introduction, management of, anatomic defect correction in,

4 564 Endometritis (continued ) antimicrobials in, 472 breeding management in, 477 ecbolic drugs in, immune modulators in, misoprostol in, prostaglandin E in, for susceptible mares, uterine lavage in, uteropexy in, 477 uterine defense mechanisms in, Equine metabolic syndrome/insulin resistance (EMS/IR) broodmares with medical management of, described, diagnostic testing for, 437 Estrus behavioral stimulation of hormone therapy in, 431 suppression of hormone therapy in, ET. See Embryo recovery and transfer (ET) Exercise in endometritis management, 508 F Flow cytometric assays in semen evaluation, 535 Follicular development stimulation of hormone therapy in, Folliculogenesis anti-müllerian hormone in, 454 Fungal organisms in infectious endometritis diagnosis, 494 G GCTs. See Granulosa cell tumors (GCTs) Gene(s) anti-müllerian hormone, 453 Granulosa cell tumors (GCTs) biomarker of in mares, 460

5 565 H Hormone(s). See specific types Hormone therapy. See also specific drugs and indications in behavioral estrus stimulation, 431 in blocked oviducts management, 433 in cervical relaxation, in clinical practice, ecbolic drugs, 429 in estrus suppression, in follicular development, in labor induction, 431 in lactation induction, in libido stimulation in stallions, 433 in luteolysis and short-cycling, in ovulation induction, in pregnancy support, 427 in retained placenta management, 432 Hydrogen peroxide in endometritis management, I ICSI. See Intracytoplasmic sperm injection (ICSI) Immunomodulators in endometritis management, 505 persistent post-breeding endometritis related, Infection(s). See also specific types uterine prevention of reproductive tract barriers to, 466 Insulin impact on reproductive function, 439 Insulin resistance (IR) described, Intracytoplasmic sperm injection (ICSI), contraindications to, indications for, 402 introduction, procedure for, documentation and arrangements, embryo culture, embryo packaging for fresh transfer, embryo shipment preparation, holding droplets/dishes preparation, 408 oocyte handling on receipt at laboratory, 405 oocyte preparation, performance, semen sample preparation, IR. See Insulin resistance (IR)

6 566 K Kerosene in endometritis management, L Labor induction of hormone therapy in, 431 Lactation induction of hormone therapy in, Leptin impact on reproductive function, Leydig cell differentiation inhibition of anti-müllerian hormone in, 454 Libido of stallions hormone therapy in stimulation of, 433 Luteolysis short-cycling and hormone therapy in, M Mare(s) anti-müllerian hormone in clinical applications of, (See also Anti-Müllerian hormone) persistent post-breeding endometritis management for, (See also Endometritis, persistent post-breeding, management of) Misoprostol in persistent post-breeding endometritis management, Müllerian ducts regression of anti-müllerian hormone in, N Nutrition in endometritis management, O Obesity impact on reproductive function, Oocyte(s) for assisted reproduction techniques, collection methods, 380 clinical problems associated with,

7 567 general procedures, from harvested ovaries, from immature follicles, from maturing dominant follicles, sedation- and analgesia-related, 380 culture and maturation of, identification of, introduction, 379 transport of ovaries and oocytes, shipment procedures, for ICSI, (See also Intracytoplasmic sperm injection (ICSI)) Ovarian reserve and function biomarker of in mares, Ovarian tissue biomarker of in mares, 458 Overenthusiastic, difficult-to-control breeding behavior in stallions diagnostic and therapeutic techniques for, Oviduct(s) blocked hormone therapy in management of, 433 Ovulation induction of hormone therapy in, Oxytocin in persistent post-breeding endometritis management, 475 P Peptide(s) antimicrobial in endometritis management, Pituitary pars intermedia dysfunction (PPID), broodmares with medical management of, diagnostic testing for, 438 reproductive function effects of, Placenta retained hormone therapy in management of, 432 PPID. See Pituitary pars intermedia dysfunction (PPID) Pregnancy hormone therapy during, 427 Prostaglandin E in persistent post-breeding endometritis management, Protein(s) in anti-müllerian hormone,

8 568 R Red blood cells in infectious endometritis diagnosis, 492 Regenerative therapies in endometritis management, 508 Reproduction endocrine diseases effects on, (See also Endocrine diseases) IR effects on, human perspective on, obesity effects on, PPID effects on, Reproduction breeding behavior disorders in stallions, inadequate sexual interest and arousal, introduction, 513 overenthusiastic, difficult-to-control breeding behavior, S Seasonality impact on reproductive function, Semen cool-shipped evaluation of modern techniques in, cryopreservation of, advances in, freezing of epididymal semen, improving semen quality in strategies for, introduction, processing procedure, adding freezing extender, concentrating sperm, freezing curves, insemination using frozen sperm, 527 packaging, 526 semen collection, semen dilution, 523 thawing and postthaw semen analysis, 527 epididymal freezing of, evaluation of modern techniques in, cool-shipped semen, flow cytometric assays, 535 interpretation of, introduction, semen volume, 533

9 sperm chromatin structure assay, sperm concentration, 534 sperm morphologic features, sperm motility, sperm quality longevity, 538 sperm viability, for ICSI preparation of, (See also Intracytoplasmic sperm injection (ICSI)) from subfertile stallions for cooled transport case examples, cushioned centrifugation, general guidelines for, gradient centrifugation, low-dose insemination, strategies for processing, volume of evaluation of modern techniques in, 533 Sertoli cell tumor immunohistochemical biomarker of in stallions, 457 Sexual interest and arousal inadequate in stallions diagnostic and therapeutic techniques for, Short-cycling luteolysis and hormone therapy in, Sperm modern techniques in evaluation of concentration-related, 534 morphologic features, motility-related, viability-related, quality of longevity of evaluation of, 538 Sperm chromatin structure assay in semen evaluation, Stallion(s) anti-müllerian hormone in clinical applications of, (See also Anti-Müllerian hormone) libido stimulation in hormone therapy for, 433 reproduction breeding behavior disorders in diagnostic and therapeutic techniques for, (See also Reproduction breeding behavior disorders, in stallions) semen of cryopreservation of, (See also Semen, cryopreservation of) 569

10 570 Stallion(s) (continued ) subfertile strategies for processing semen from for cooled transport, (See also Semen, from subfertile stallions) T Tumor(s) granulosa cell biomarker of, 460 Sertoli cell immunohistochemical biomarker of in stallions, 457 U Ultrasound in persistent post-breeding endometritis evaluation, 471 Uterine epithelial cells in infectious endometritis diagnosis, Uterine immune response, Uterine infection prevention of reproductive tract barriers to, 466 Uterine irrigation/lavage in endometritis management, 503 Uterine lavage in persistent post-breeding endometritis management, Uteropexy in persistent post-breeding endometritis management, 477 Uterus samples from collection methods, advanced or confirmatory methods, preparation of mare, evaluation of, cytology in, (See also Cytology, in infectious endometritis diagnosis) microbiology in, W White blood cells in infectious endometritis diagnosis, 492 Y Yeast(s) in infectious endometritis diagnosis, 494

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