Amino acids for all nutritional applications. Highly purified. High-quality European supply.

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1 Amino acids for all nutritional applications Highly purified. High-quality European supply.

2 Nutrition & Care at Evonik Ensuring a supply of healthy, nutritious and varied food for a growing and diverse world population is one of the great challenges of the 21st century. Finding new and better ways to meet it is what the global health and nutrition megatrend is about and it is core to Evonik. Scarcer land resources for farming impact the issue of sufficient food quantity. Rising life expectancy creates new nutritional requirements for food products destined to the elderly. And the growing importance of leading a healthy lifestyle combined with a balanced diet is driving demand for foods that contribute to better health and wellbeing. At the same time, rising demand for better food at a lower cost is enticing as some producers to cut corners, entailing health risks that led to the global scandals that have made the headlines in recent years. Consumers demand that top food quality also means absolute food safety. In developed countries, in particular, changing dietary habits have led to pathologies, from allergies to diabetes to obesity, that place new demands on processors and manufacturers for providing health-enhancing foods. As their understanding of nutrition increases, consumers want their foods to meet targeted requirements and deliver specific nutrients. Food manufacturers around the world are facing new and complex challenges that are forcing a rethink of their products and processes in terms of both delivering what customers want and keeping costs under control while meeting evertougher health, quality and sustainability standards. At the same time, evolving lifestyles are creating new market opportunities for foods that still have to be invented. As the premier supplier of amino acids and their derivatives, Evonik has over the past five decades evolved into the food industry s preferred partner for realizing the potential in creating better, healthier foods to meet the demands of a global, growing, and increasingly diverse and demanding consumer base. Meeting your nutritional challenges. L+L vnd Broschuere Rexiva, A4.indd 31. Aug 2018; 11:4 Uhr

3 Health & Nutrition The basic human need for food has become a concern in ways that previous generations would never have imagined. Our solutions help produce the healthy, nutritious components of a balanced diet with peace of mind for today and tomorrow.

4 More than food supplements, value supplements. Dietary Supplements Infant Nutrition Food supplementation allows to meet specific nutritional needs of different categories of people. In this area, the applications of amino acids and related products are very diverse, e.g.: Where standard cow s milk or soy-based infant formula fall short, amino-acid-enriched formulas consistently prove effective in adressing specific newborn needs or concerns. This includes: Supplements to prevent denutrition or sarkopenia Enhancement of cognitive performances and prevention of fatigue Improvement of memory Ammonia detoxification of the body Specific formulations for babies with food allergies, such as lactose intolerance Aliments for premature babies to support growth and the development of the immune system L+L vnd Broschuere Rexiva, A4.indd 31. Aug 2018; 11:4 Uhr

5 What Evonik brings to the table: over six decades of experience in addressing the evolving needs for better quality, performance and value in nutritional products with amino acids and related compounds. Sport Nutrition Flavors Sport practice is nowadays part of a healthy life style. Our products address the requirements of active people as well as professionals, athletes: Stimulation of protein synthesis and muscle growth Improvement of regeneration after training Improvement of athletic performance Ammonia detoxification of the body Reduction of muscle fatigue Amino acids can give flavor to food products on their own, but mainly by reaction with other food components during cooking. Amino acids manufactured by fermentation are adapted to the production of natural aromas and flavors: Flavor enhancer for beefy or sweet taste Ingredients for the synthesis of aromas

6 More than a promise of quality At the core of the REXIVA brand is a unique combination of chemistry, biotechnology, and purification technology. It enables us not only to adapt amino acids to the requirements of the food industry as a whole, but also to the specific food formulation needs of our customers. Add to this a level of backward integration in our sourcing, manufacturing and logistics that ensures unrivalled supply security. You can also count on the fact that the toughest quality and regulatory standards are met every step of the way. AMINO ACIDS Do you need amino acids in top quality? Ask the expert! Amino acids are building blocks for life, constituents of proteins. As such, they are involved in most of the biochemical processes within the body. Amino acid supplementation in foods may help active people to improve their physical condition. It can also alleviate the effects of specific allergies or gastro-intestinal disorders, for instance, enabling those afflicted to lead a normal life. L+L vnd Broschuere Rexiva, A4.indd 31. Aug 2018; 11:4 Uhr

7 SPECIALTIES FOR NUTRITION APPLICATIONS Are you looking for specific ingredients for your nutrition application? We have the solution! Besides single L-amino acids, we can offer several specific ingredients for taking your formulation to where you want it. Amino acids salts: Amino acid salts combine two aspects together. At least one of the components is an amino acid. The other could be as well an amino acid as another component such as HCl. Keto acids: Keto acids can be converted into the corresponding amino acids by binding the ammonia produced during protein decomposition within the body. These amino acids can then be used for protein synthesis or as energy providers without increasing the level of free ammonia. Therefore, keto acids stimulate the ammonia detoxification of the body, and they enhance muscle by preventing muscle damage from intensive training (anti-catabolic effect). As one of the larger manufacturers of keto acids, Evonik offers a wide range of products at high purity level. Peptides: In some cases, where stability and solubility are especially sensitive, dipeptides may prove the better alternative to single amino acids. Evonik has extensive experience in manufac turing di- and tripeptides at large volumes from kilos to multiple tons.

8 REGULATORY Evonik s solutions for food manufacturers come with extensive experience in amino acid manufacturing and processing and in the highest quality grades required by the nutrition industry: Non-GMO, non-animal origin HACCP compliant quality system ISO 9001, 14001, certified plants and facilities Full control of all quality parameters (purity, microbiology, heavy metals, etc.) Analytical methods in compliance with USP, FCC, Codex Alimentarius Kosher and halal certification FDA and ANSM approval Statements on allergens, residual solvents and BSE/TSE are available L+L vnd Broschuere Rexiva, A4.indd 31. Aug 2018; 11:4 Uhr

9 As good, healthy and nutritious food ingredients may be, the finished product must be safe. Absolutely safe. And that means processes that leave no room for doubt. Evonik understands that commitment to safety is a promise that your pro ducts must keep over and over again. That s why we take it so much to heart. CUSTOMIZED SOLUTIONS Are you facing a specific technological challenge? You can count on us! The experience and resources we bring to bear on solving your problems, along with the facilities at our disposal, also means more meaningful results in less time. Customer-specific process development: We can develop for our customers any kind of amino acid derivatives, or complex formulations they cannot get elsewhere. Challenge us, and our expertise in amino acid and amino acid derivative manufacturing mesh gears with your technology network. Purification services: With us, you share in several decades of experience in the purification of natural materials with chromatographic technologies at large scale. Contact us for any separation job. Formulation Technology: If you have issues with your formulation development, our expertise could help crack the nut! Building on broad expertise and a vast array of technical capabilities (at lab and industrial scales), Evonik is uniquely equipped to develop solutions that specifically improve the properties of your product: Particle size design for solubility and bioavailability enhancement Coating / encapsulation for specific release profiles or taste masking Particle size distribution optimization to improve macroscopic properties (density, compaction, ) Premixes: Mixing different ingredients is increasingly common practice in food applications. Our expertise and experience in this area is your best guarantee of easy processability and consistent quality for the manufacturing of your pre-mixes.

10 Amino acids for nutrition applications L+L vnd Broschuere Rexiva, A4.indd 31. Aug 2018; 11:5 Uhr

11 PRODUCT OVERVIEW CAS No. Amino acids and their salts DL-Alanine DL-Methionine Glycine L-Alanine L-Arginine-L-aspartate L-Arginine-L-pyroglutamate L-Aspartic acid L-Isoleucine L-Leucine L-Lysine acetate L-Lysine hydrochloride L-Lysine-l-aspartate L-Lysine-L-glutamate dihydrate L-Methionine L-Ornithine hydrochloride L-Proline L-Serine L-Threonine L-Tryptophan L-Valine N-Acetyl-L-methionine Peptides L-Alanyl-L-glutamine Keto acids and their salts α-ketoglutaric acid L-Arginine-α-ketoglutarate

12 This information and all further technical advice are based on our present knowledge and experience. However, it implies no liability or other legal responsibility on our part, including with regard to existing third party intellectual property rights, especially patent rights. In particular, no warranty, whether express or implied, or guarantee of product properties in the legal sense is intended or implied. We reserve the right to make any changes according to technological progress or further developments. The customer is not released from the obligation to conduct careful inspection and testing of incoming goods. Performance of the product described herein should be verified by testing, which should be carried out only by qualified experts in the sole responsibility of a customer. Reference to trade names used by other companies is neither a recommendation, nor does it imply that similar products could not be used. REXIVA reg. trademark of Evonik Industries AG and its subsidiaries AFI-V3 EVONIK NUTRITION & CARE GmbH Health Care Business Line Pharma & Food Ingredients rexiva@evonik.com

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