FDA/CFSAN: Food Irradiation
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1 LIVE INTERACTIVE YOUR DESKTOP FDA/CFSAN: Food Irradiation Presented by: Dr. Lane Highbarger Tuesday, May 11, 2010
2 Food Irradiation Lane A. Highbarger, Ph.D. Division of Biotechnology and GRAS Notice Review Office of Food Additive Safety Center for Food Safety and Applied Nutrition May 11, 2010
3 Poll Question Have you ever knowingly purchased an irradiated food? A) Yes B) No C) How would I know?
4 Energy
5 Radiation Spectrum
6 Sources of Radiation Cobalt MeV Cesium kev Electron accelerators operated at 10 MeV or less X-ray generators operated at 7.5 MeV or less
7 Dose What it Means Irradiation doses are measured in gray (Gy) Gy is measured in joule/kg absorbed energy J Kg 1 Gy = 1 = 1 m 2 s -2 For X-rays and gamma rays == Sievert Energy sources are constant Applied dose = energy source time exposed Absorbed dose depends on other factors
8 Food Irradiation Facilities Gamma Electron beam
9 Let s Pause for Questions?
10 Food Irradiation Overview
11 A Brief History of Food Irradiation 1905 Begins the era of food irradiation Congress defines a source of radiation as a food additive Foods irradiated up to 10 kgy considered to be safe and wholesome Foods irradiated at any dose should be considered as safe and as wholesome as foods treated by any other conventional process Irradiation is used to eliminate possible traces of Anthrax FDA approves the use of irradiation in a variety of foods.
12 Low Dose (<1 kgy) Control insects Inhibit maturation Inhibit sprouting Why Irradiate? Medium Dose (1-10 kgy) Extend shelf life Reduce microorganism level High Dose (> 30 kgy) Sterilize - analogous to canning Decontaminate certain food additives, e.g., spices
13 Foods Permitted to Be Irradiated Under FDA s Regulations All foods Arthropod Control 1 kgy max Dry Enzyme Preps. Microbial Control 10 kgy max Fresh Foods Maturation Inhibition 1 kgy max Spices/Seasonings Microbial Control 30 kgy max Poultry Microbial Control 3 kgy max Seeds for sprouting Microbial Control 8 kgy max Shell eggs Microbial Control 3 kgy max Meat and meat byproducts Microbial Control 4 kgy/7 kgy Molluscan shellfish Microbial Control 5.5 kgy max Fresh lettuce and spinach Microbial Control 4 kgy max NASA Sterilization 44 kgy min
14 Other Irradiated Substances Medical equipment Laboratory animal diets Poultry feed Pet foods, treats and chews Microbial Control Microbial Control 50 kgy max Salmonella spp. 25 kgy max Salmonella spp. 50 kgy max
15 Best return on irradiation Which foods do you think would benefit most from being irradiated? Either from a food safety point of view or a commercial point of view. A) Ground beef B) Lettuce C) Shell eggs D) Fruits E) NASA beefsteak
16 Let s Pause for Questions?
17 Irradiation Action
18 E-beam shallow penetration Converted to x-ray for more penetration Gamma deeper penetration All act via similar mechanisms
19 Mammals > Insects > Single Celled Organisms > Viruses; (Prions Likely Resistant) D 10 The radiation dose needed to inactivate 90% of the microbial load in the food medium
20 All bacteria have different susceptibilities to radiation (values in kgy) Salmonella spp Listeria monocytogenes E. coli O157:H A % reduction = 5 x D 10 value
21 Which number sounds better as a descriptor for the reduction of a bacterial population? And which one is the greatest kill? A) 5000 times B) 99.99% C) Reduced by 10-5 D) A 4 D 10 reduction E) I have a headache now
22 Let s Pause for Questions?
23 Safety Considerations
24 Safety Considerations Radiological Safety Chemical Change and Potential Toxicity Nutritional Adequacy Potential Microbiological Hazard
25 Chemical Change Energy stimulates chemistry Increases when liquid is present Initiates reaction with air Generally little but not necessarily negligible change Can be controlled by controlling conditions
26 Heated Lipid (180 ºC/1Hr) vs Irrad (120 kgy)
27 Nutrition Issues Vitamins can be labile to heat and irradiation
28 Microbiological Radiation sensitivity varies with species Sensitivity varies with environment Temperature; water Activity; ph; Salt; etc
29 Poll Question Has an explanation about food irradiation made you feel more or less comfortable about purchasing irradiated foods? More Les Do you want more information? Yes No
30 Let s Pause for Questions?
31 Foods Currently Under Review Crustaceans Multiple-ingredient products Non-refrigerated meat food products Poultry Dietary supplements
32 Labeling Criteria The FDA requires that irradiated foods bear the radura label and state on the label Treated with radiation or Treated by irradiation There is no statutory requirement specific to irradiation
33 Poll Quesiton Would you prefer to have food labeled if it were irradiated? Yes X No
34 Controversy and Queries Objections Consumer Public Citizen / Center for Food Safety Formal Correspondence
35 Let s Pause for Questions?
36 Other non-thermal Mitigation Technologies
37 High Pressure Processing 80k 130k lb/in 2 Effective at elimination of microbial contamination Spores are resistant Expensive
38 Pulsed Field Short bursts of electricity used for microbial control. Liquids, e.g., juice, milk, liquid eggs. Low cost.
39 UV Radiation Effective at microbial decontamination in liquids. Approved for use in surface decontamination. Approved for use in juices.
40 Web Based Information Resources Food Safety and Irradiation Food Irradiation Processors Alliance Kansas State University USDA Fact sheet FSIS on labeling Food Safety dot gov Printable information: Irradiated Lettuce and Spinach Recent News: E. coli O145 in romaine lettuce WSJ Blog on E. Coli
41 Thank you to the sponsor of tonight's Web Seminar:
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44 National Science Teachers Association Dr. Francis Q. Eberle, Executive Director Zipporah Miller, Associate Executive Director Conferences and Programs Al Byers, Assistant Executive Director e-learning NSTA Web Seminars Paul Tingler, Director Jeff Layman, Technical Coordinator LIVE INTERACTIVE YOUR DESKTOP
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