Nestlé Investor Seminar 2007

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1 Nestlé Investor Seminar 2007 Nestlé Research The Engine for Nutrition, Health and Wellness Prof. Dr-Ing. Werner Bauer Chief Technology Officer 1 Nestlé Investor Seminar - Vevey June 7-8, 2007 Name of chairman

2 Disclaimer This presentation contains forward looking statements which reflect Management s current views and estimates. The forward looking statements involve certain risks and uncertainties that could cause actual results to differ materially from those contained in the forward looking statements. Potential risks and uncertainties include such factors as general economic conditions, foreign exchange fluctuations, competitive product and pricing pressures and regulatory developments. 2 Nestlé Investor Seminar - Vevey June 7-8, 2007 Name of chairman

3 Nestlé Research The Engine for Nutrition, Health and Wellness Prof. Dr.- Ing. Werner Bauer Chief Technology Officer 3/ June 2007

4 Our competitive advantage is our strong innovation heritage Future Years Success Story in Research 4/ June 2007

5 Our competitive advantage is a clear vision for the future, based on superior science and consumer understanding Good Food Good Life! 5/ June 2007

6 Our competitive advantage is flawless execution that starts and ends with consumers Innovation Strategy Exploration Execution Assessment Innovation Strategy LAUNCH Gate 0 Gate 1 Gate 2 Gate 3 Gate 4 Gate 5 Gate 6 Consumer Winning Idea Winning Concept Product & Business Plan Pre-launch Go Launch Monitoring Review Evaluation of launch Consumer Idea Assessment Initial Business Plan Confirmed Business Plan Updated Business plan 6/ June 2007

7 Above all, we have a strong Nutrition Business at the core of our Food and Beverage Business to strengthen our science-based development the reach of Nestlé Research the consumer-centric approach 7/ June 2007

8 Nestlé Nutrition is the catalyst for superior research Leveraging abcdef Scale Innovating the abcdef Food & Beverage Business 8/ June 2007

9 Changes in nutritional concepts Life Expectancy Adult Energy Consumption Public Health Vitamins Iodine Targeted Nutrition Low Fat/Low Salt Probiotics Individualized Nutrition Biomarkers Genetic Profiling Nutrient Efficacy 9/ June 2007

10 In Nestlé products, health benefits are provided by science R Vitality / Protection Immunity & Protection Heart Health Long-Lasting Energy Easy Digestion Branded Active Benefits are science-based Intestinal Health Growth & Development Building Stronger Bones Energy Release Cholesterol Control Long-Lasting Alertness Feeling Good, & It Shows Refuelling Growth Helps Keep Calcium in your Bones Gut Comfort Consumers Branded Active Benefits Scientists Food with health benefit Scientific evidence for health benefit 10 / June 2007

11 How do we make it happen? 11 / June 2007

12 The Nestlé Innovation Model What is needed by consumers? What is technically and scientifically possible? What is commercially achievable? Bigger opportunities Bolder initiatives Better execution 12 / June 2007

13 Success factors for Bigger, Bolder, Better innovation Bigger opportunities Focus on key brands Fewer and Bigger projects Consumer centric around opportunities Bolder initiatives Leading science and new technologies New systems, routes to market, business models, businesses Better execution Early involvement of all key functions Speed to market, rigorous deployment Clear organization and processes, best practices and tools Decisiveness, consistency and continuity 13 / June 2007

14 Nestlé vision Be the Nutrition, Health and Wellness company Innovation driven by superior science and technology Understand consumer s nutritional and emotional needs Invent the future: move faster and go beyond what the consumer tells us Nestlé Research vision Nutrition research and medical science at the core Science and technology as the engine of innovation Be consumer centric Innovation beyond products Chief Technology Officer Focus Leading science and technology Consumer benefit research Open innovation model Innovation culture Passionate people Flawless Execution 14 / June 2007

15 Our Open Innovation model: Partnerships multiply our opportunities Business Key Suppliers Focus Venture Capital Immunprotection Brain function Benefit areas Universities, Start-Ups The wider Nestlé Personalized Nutrition Direct to consumer distribution model Early Development Stage Mature 15 / June 2007

16 The "wider" Nestlé Skin, allergies, infections Infant Formula to avoid skin allergies Skin health Hair, skin Beauty from within Skin health and protection Eye, ear, nose, throat infections Fight otitis media through Infant Formula Sofinol Healthy lipids Clinical Nutrition Infant Formula 16 / June 2007

17 University partnerships: Food and brain development The entire brain can be imaged according to molecular distribution Single Voxel Responses & Real-Time BOLD Imaging Brain function is about fuelling and prioritization Nestlé has formed a partnership with the EPFL to develop the world s leading diet and brain research programme Nikos K. Logothetis 3rd Nestlé International Nutrition Symposium Nestlé Research Center 17 / June 2007

18 University partnerships: Diet influences genes and the metabolism The genetic background of individuals plays an essential role in their predisposition to certain diseases Nestlé and INMEGEN will study the genetic make-up of and pre-disposition to food-related diseases such as obesity and diabetes Transcription Translation Post-translational modification Enzymatic activity 18 / June 2007

19 Nestlé's venture capital value chain Access Growth Integration 380 MM 500 MM VC FUNDS Life Ventures Burrill Nx Sherbrooke I V. Incubator W.Health Scientificallyvalidated health & wellness opportunities NESTLÉ Technology-focused Concept validation Early stage development Products, services, & Route-to-Market focus Mid- to late-stage investment Business building Businesses - Integration opportunity Intellectual assets adopted to existing businesses e.g. BABs 19 / June 2007

20 Nestlé Research focus for nutrition research Health Benefit Areas Protection Weight Management Skin Health & Beauty Growth & Development Healthy Ageing Performance Digestive Comfort 20 / June 2007

21 Developing leading science and technologies to deliver Nutrition, Health and Wellness Business Driver Key Health Consumer Benefits Areas Projects Nestlé Research Coffee & Bev. Health Nutrition & Health Confectionery Digestive Comfort Probiotics Culinary Dairy Ice Cream Infant Nutrition Baby Food Protection Weight Control Pleasure X-biotics Probio& Allergy Probiofor Pets Glucose Absorption Science and Technology Platforms Pet Care Sensory & Satiety 21 / June 2007

22 Research pipeline to develop healthy foods: From consumer insight to healthy products Consumer Insight Pipelines of Research Ingredients / Foods Biologically-based consumer insight Consumer behaviour: Psychology Sociology Anthropology Biological target(s) Food grade bioactives Animal & clinical studies Scientific proof of benefits Safety Protection / IP Formulation optimization Compliance Regulatory approval (Claim, Novel food...) Communication 22 / June 2007

23 The product development pipeline for healthy foods Bioavailability Clinical Trials Product Formulation Process Optimization In Vivo Legal & Regulatory Approval Product Launch In Vitro Making healthy people healthier 23 / June 2007

24 Our science in action Probiotics changing the Nutrition world Collection Screening Safety & Efficacy studies Pre-clinical studies Clinical evaluation Nestlé Culture Collection ~2,600 strains Candidate Strains ~200 Promising Strains ~40-50 ~1-3 Strains Final product Consumer benefit Isolation Identification Characterisation Safety Stability Efficacy Diarrhea Inflammation Gut comfort Allergy 24 / June 2007

25 One benefit for different products Probiotics for gut protection Probiotics for skin protection Goal: Help the body's own natural defenses restore the natural balance of «good» bacteria in the gut Benefit: Immunostimulation Competitive displacement of pathogens in the gut Protection against Helicobacter pylori infections Goal: Identify nutrients with benefits link to photoprotection Benefit: Accelerated and complete recuperation of skin cell defenses after UV exposure Intensified tanning color Decreased skin sensitivity to UV 25 / June 2007

26 Science roadmap to personal health We need to master all levels of biology Genes Proteins Metabolites Organism Information Genomics Structure/Activity Proteomics Composition Metabolomics Phenotype Develop new products targeted to the specific needs of a population Influence expression of specific genes, which lead to the development of foods that can improve health and wellness 26 / June 2007

27 Biomarkers for metabolic disorders: Metabolomics Gut microbiota modulates Gastro-Intestinal Physiology Gastro-Intestinal Disorders Nutritional Intervention Efficacy Ulcerative colitis Irritable Bowel Disease with Probiotic Crohn s disease Control Control Glycerol Amino acids IBD Control Acetate Region-specific changes by probiotics influences: digestion absorption of nutrients energy metabolism lipid synthesis and protective functions Early diagnostics of Gastro- Intestinal disorders Irritable Bowel Syndrome Irritable Bowel Disease Crohn s disease Closer to healthier states 27 / June 2007

28 Nutrigenomics offers new ways to provide optimal nutrition Better understand health through an insight into the mechanisms of prevention and protection Biomarkers based on genomics were used to show positive effect of the food products Osteoarthritis leads to the expression of specific genes, which can be used as biomarkers A diet for dogs with osteoarthritis developed from nutrigenomic research 28 / June 2007

29 Biomarkers correlating caloric restriction on canine health and life span Long-term restriction of energy intake has been shown to prolong life and delay age-related morbidity Ageing and dietary restriction modify the composition or functional activities of gut microbiota Nestlé aims to reduce the impact of age related diseases and to provide more general insights into extension of longevity in dogs Journal of Proteome Research Vol. 6, No. 5, / June 2007

30 How do we measure success? 30 / June 2007

31 Measuring success Consumer satisfaction and brand equity Successful innovations, rapidly rolled out Continuous improvement and renovation Taste and nutrition superiority, 60/40+ Organic growth, EBIT margin and return on investment 31 / June 2007

32 Strong Science supports Strong Brands NIDO Nutri-Light Drinking Yogurt Spoonable Yogurt Marginal contribution index ALL AGES Value Added "Children s Specialties NIDO NUTRITION SYSTEM NIDO FULL CREAM year 32 / June 2007

33 Nestlé Pure Life: building an idea into a CHF 1 billion business in 8 years Speed: briefed 1997, launched 1998 in Pakistan Rigorous deployment: roll-out in 22 markets Continuity in building brand equity Nestlé Pure Life Continuous innovation 2010 vision: CHF 3 bio Safe and affordable water Multi-source model Treated and remineralized Nestlé Pure Life Splash (North America) Nestlé Pure Life Limonada (Argentina) NPS mio CHF Vol. mio litres / June 2007

34 Nestlé Research Local Relevance and global scale Markets Nestlé Research Suppliers Biotech Start-ups Universities Research Institutes 280 Application Groups 18 Research and Development Centres 1 Research Centre R&D Investment CHF Billion ,500 people / June 2007

35 Nestlé Research Leveraging nutrition research Markets 280 Application Groups Nestlé Research Suppliers Biotech Start-ups Universities Research Institutes 21 Research and Development Centres 1 Research Centre Leveraging abcdef Scale + Novartis Medical Nutrition + Gerber 35 / June 2007

36 Bigger, Bolder, Better Innovation building on a strong Innovation heritage a clear vision for the future based on superior science and consumer understanding flawless execution that starts and ends with the consumer above all, Research is our DNA and Nutrition is the heart of Nestlé 36 / June 2007

37 Nestlé Research The Engine for Nutrition, Health and Wellness 37 / June 2007

38 Nestlé Investor Seminar Nestlé Investor Seminar - Vevey June 7-8, 2007 Name of chairman

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