Joint FAO/WHO Expert Committee on Food Additives (JECFA) Eighty third meeting Rome, Italy, 8 to 17 November 2016
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1 Joint FAO/WHO Expert Committee on Food Additives (JECFA) Eighty third meeting Rome, Italy, 8 to 17 November 2016 WHO Experts participating in the meeting Published on 23 September2016 For the list of FAO experts, follow the link below: List of Experts The following list of experts is proposed for the meeting. Please find below their bio-sketches. If you have any comments, please contact us at jecfa@who.int no later than 14 October, ALEXANDER Jan Prof. Alexander is a specialist in Occupational Medicine and EUROTOX Registered Toxicologist. He has been a Department and Division Head at the NIPH. He has coauthored more than 250 research publications in the area of toxicology of metals, natural toxins, food processing- and environmental contaminants, chemical carcinogenesis and epidemiology. He has worked with food chemical safety and nutrition for more than 30 years and served at Norwegian and Nordic Committees on food safety. He is currently chairing the Norwegian Scientific Committee of Food Safety and has been member of the former EU Scientific Committee on Food and served on the EFSA CONTAM Panel for 10 years and 3 years as a vice Chair of EFSA Scientific Committee. He has been member of JECFA on several occasions. He has served as a head of the toxicology section and board member of the Norwegian Society for Pharmacology and Toxicology. Honors include Wellcome visiting professor University of North Dakota 1997, Edvard Poulsson Medal in recognition of toxicology 2015, BCPT Nordic Prize in recognition of Food Safety and Nutrition ARNICH Nathalie Nathalie ARNICH is a toxicologist PhD with 13 years of experience in health risk assessment associated with contaminants in food. Since 2003, she has been working at AFSSA (the French Food Safety Agency) that became ANSES on 1 st July 2010, located near Paris. She is currently Deputy Head of the unit on food risk assessment and is responsible for health risk assessment and/or scientific advice on request from French ministries in the field of biological hazards, biotechnology (GMO, food enzymes), guides on good hygiene practices, marine and freshwater biotoxines, in relation with ANSES scientific panels and working groups. Previously, Nathalie has been involved in the scientific coordination of ANSES/AFSSA s scientific panel on Food Contact Materials (June 2009-April 2012) and on Chemical Contaminants in food (until June 2009). Nathalie joined Health Canada (Food Directorate, Ottawa) as a senior toxicologist evaluator from May 2012 to July Nathalie is listed on the JECFA roster of Toxicological Experts BARLOW Sue Sue Barlow has been involved in risk assessment of chemicals and food for many years. In her early career in academia she worked in reproductive/developmental toxicology research and taught pharmacology. She then worked in regulatory toxicology in the UK Department of Health and became chief scientist. Since 1996, she has been an independent consultant in toxicology. She has been a temporary adviser to JECFA since 2005 and a member of the WHO Expert Advisory Panel on 1 of 6
2 Food Safety since She was involved in the preparation of the 2009 FAO/WHO guide to JECFA and JMPR Principles and Methods for the Risk Assessment of Chemicals in Food and was a coeditor of the 2002 IPCS-WHO/ILO/UNEP Global Assessment of the State-of-the Science of Endocrine Disrupters. She was a member Veterinary International Cooperation on Harmonisation Safety Working Group. She is an evaluator and reviewer for research proposals and projects funded by European Commission. She was a member of the European Commission s Scientific Committee on Food for 10 years. From she chaired the European Food Safety Authority s Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food. She was a member of EFSA s Scientific Committee from BENFORD Diane Dr Diane Benford is head of the Risk Assessment Unit at the UK Food Standards Agency. The Unit has overall responsibility for advice on risks associated with all types of chemicals in food and of microbial food contamination, but much of Diane s work focuses on chemical contaminants, food additives and natural toxicants. Diane s background is in toxicology, with particular expertise in mechanisms of toxicity and risk assessment. Her role at the Food Standards Agency also includes acting as scientific secretary to the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) and part of the joint secretariat to its sister committee on Mutagenicity (COM) and Carcinogenicity (COC). In a personal capacity, Diane was a member of the scientific panel on contaminants in the food chain [CONTAM] of the European Food Safety Authority (EFSA) from 2006 to 2015, acting as chair of the panel for the final 3 year term of office. She is now a member and vice-chair of the EFSA Scientific Committee. She has participated in meetings of JECFA since 2001, firstly as a WHO Temporary Advisor and since 2013 as a member. BOLGER P. Michael Dr. Bolger received his bachelor s degree in biology in 1971 from Villanova University and his doctoral degree in physiology and biophysics in 1976 from Georgetown University. After a three year postdoctoral position at the Georgetown University Medical Center, Dr. Bolger became a staff fellow in toxicology with the Bureau of Foods in the U.S. Food and Drug Administration (FDA). Upon completion of his staff fellowship, he accepted a position as a toxicologist with the Contaminants Branch, Center for Food Safety and Applied Nutrition, US Food and Drug Administration. Since 1980 Dr. Bolger has been involved in the hazard/safety/risk assessment of anthropogenic and naturally derived contaminants in food. Dr. Bolger is a board-certified toxicologist by the American Board of Toxicology. Dr. Bolger is the recipient of the 2009 Arnold J. Lehman Award conferred by the Society of Toxicology and the 2010 Outstanding Risk Practitioner Award conferred by the Society of Risk Analysis. Until 2012 Dr. Bolger was director of the Chemical Hazards Assessment Staff in the Office of Food Safety, Center for Food Safety and Applied Nutrition, US Food and Drug Administration which was responsible for the hazard/safety/risk assessment of food borne contaminants, and for reporting FDA monitoring efforts on food-borne environmental contaminants and the conduct of exposure assessments. Presently Dr. Bolger is a Senior Managing Scientist at the Center for Chemical Regulation and Food Safety, Exponent in Washington DC. Dr. Bolger is also currently serving as a food safety expert of the World Health Organization and is a member of the Joint Expert Committee on Food Additives and the Foodborne Disease Burden Epidemiology Reference Group of the World Health Organization. CARRINGTON Clark Dr. Clark Carrington earned his Ph.D. degree in Pharmacology in 1984 at Duke University in Durham, NC. Dr. Carrington also received an NIH postdoctoral fellowship in Toxicology and was a Research Associate at Duke where his primary interest was on the neurotoxicology of organophosphorous compounds. In 1989, Dr. Carrington joined the U.S. Food and Drug Administration where he worked in the Branch concerned with contaminants in food in the Center for Food Safety and Applied Nutrition until In addition to serving as a general toxicologist and dealing with a wide variety of toxicological issues, Dr. Carrington specialized in dose-response modeling and quantitative risk 2 of 6
3 analysis. In addition to authoring several dozen journal articles, Dr. Carrington has coauthored multiple reports issued by the USFDA, WHO, and FAO. Dr. Carrington is also a diplomate of the American Board of Toxicology. DOERGE Daniel Daniel R. Doerge was awarded the B.S. degree from Oregon State University and the Ph.D. degree from University of California, Davis. He was Assistant/Associate Professor of Environmental Biochemistry at the University of Hawaii. Since 1992, he has been a Research Chemist in the Division of Biochemical Toxicology at the U.S. Food and Drug Administration s National Center for Toxicological Research in Jefferson, AR. His areas of research specialization have been: chemical and biochemical mechanisms of toxicity; thyroid toxicology; toxicology of soy isoflavones, acrylamide, bisphenol A, and inorganic arsenic; applications of modern mass spectrometry that emphasize high throughput determinations of pharmacokinetics and DNA adducts; and chemical risk assessment. A common strategy in this food safety research is the integration of toxicokinetics and human biomonitoring with PBPK modeling to minimize uncertainty in the extrapolation of human risks from experimental animal toxicity testing. More than 270 peer-reviewed publications have resulted from this work. Dr. Doerge has served on chemical risk assessment advisory committees for the European Food Safety Authority ( ), the World Health Organization (2005, 2010, 2016), and the U.S. Environmental Protection Agency (2008, 2014). He also served as Editor-in-Chief for Archives of Environmental Contamination and Toxicology ( ). EDLER Lutz Lutz Edler has been senior biostatistician for 31 years in the Division of Biostatistics of the German Cancer Research Center in Heidelberg, chairing it from 1991 until retirement in 2010 with responsibilities for mathematical modelling and data analysis, human and animal carcinogenesis and risk assessment, design of animal experiments accounting for animal protection, design and analysis of clinical trials, computational statistics, pharmacokinetics, pharmacogenomics and general statistical consulting. He published about 240 journal articles, about 80 book chapters, co-edited a monograph on statistical methods for risk assessment and was editor of the Biometrical Journal from He has been member of all major statistical societies, receiving honorary lifetime membership awards in 2014 and 2016 and was responsible biostatistician in the Central European Society of Anticancer Research for 20 years. He was member of scientific advisory panels of the US EPA. and is member of the Ethics Committee of the University of Heidelberg since Currently, he is member of the CONTAM Panel of EFSA as co-chair and chairs its working group on Fusarium mycotoxins. He is also member of expert groups on contaminants and mycotoxins of the Federal Institute for Risk Assessment (BfR) of Germany. ENGELI Barbara Barbara Engeli is toxicologist at the Risk Assessment Division of the Swiss Federal Food Safety and Veterinary Office where she is head of the toxicology group since She has 12 years of experience in human regulatory toxicology and in performing risk assessments of chemicals in food and commodities, with focus on botanical preparations, food supplements, contaminants, veterinary drug residues and cosmetics. She is also member of the Emerging Risk Exchange Network of the European Food Safety Authority (EFSA) and EFSA Focal Point (observer) for Switzerland. Since 2012, she is member of the working group food constituents of the German Senate Commission on Food Safety (SKLM) of the German Research Foundation (DFG). In 2006, she was temporary advisor for the JECFA monograph on ethyl carbamate. Before joining the FSVO, she worked as scientific officer and as project leader for clinical human trials. FEELEY Mark Mark Feeley is the Associate Director, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada. The Bureau of Chemical Safety of Health Canada is responsible for policy, standard setting, risk assessment, research and evaluation activities with respect to chemicals in foods in Canada. Major programs for the Bureau of Chemical Safety include food additives, food 3 of 6
4 contaminants (natural and anthropogenic), food packaging materials, food allergens and Novel foods, including GMOs. Mr. Feeley also serves as the chair of the Health Canada Animal Care Committee. Mark Feeley is currently the Head of the Canadian delegation for the Codex Committee on Contaminants in Food (CCCF), a member of both the Joint FAO/WHO Expert Committee on Food Additives (JECFA) Roster of Toxicological and Epidemiological Experts and of the World Health Organization Expert Advisory Panel on Food Safety. Mr. Feeley has published over 75 original research articles/book chapters on topics ranging from the safety assessment of food additives to human biomarkers for chemical contaminants. He has also been an invited expert to a number of international consultations dealing with various chemical food safety topics including melamine, BPA, Dioxins and Risk:Benefit analysis of fish consumption. Mr. Feeley is currently an associate editor with the journal Food and Chemical Toxicology. GILLESPIE Zoe Ms. Gillespie has been a Senior Scientific Advisor for the Bureau of Chemical Safety, in the Food Directorate at Health Canada since January In this position, Ms.Gillespie is responsible for coordinating research and regulatory initiatives for priority setting and providing toxicology expertise for risk assessments of chemicals in food. Ms.Gillespie joined Health Canada in 2002 after obtaining her BSc Honours from the University of Guelph with a specialization in Biomedical Toxicology, gaining over a decade of extensive experience as a regulatory toxicologist and conducting risk assessments on pesticides, food additives, genetically modified foods, food contact materials, food contaminants and natural toxins. MILLER David Dr. Miller began his career at Agriculture Canada working on Fusarium mycotoxins in He became a Professor & NSERC Research Chair at Carleton University in Dr. Miller has published >350 papers on fungi and fungal toxins and has co-written and edited 9 books on public health aspects of fungi and fungal toxins. He participated in IARC Monographs 56 (1992) and 86 (2002). He was a member of the drafting committee of the IPCS monograph on fumonisin B1 (2000). Miller was a co-author of IARC publication Improving public health through mycotoxin control (2013). With Professors Chris Wild and John Groopman, he co-edited the report Mycotoxin Control in Low- and Middle-Income Countries (2015). He was a member of the Toxicology Study Selection and Review Committee that considers compounds nominated by the US Food and Drug Administration to the National Toxicology Program. Among many other awards, he received the AgExcellence Award from Agriculture Canada (1992), Ministry of Agriculture of China, Science and Technology Award for work on Fusarium (1994), the Toxicology Forum Scott Award for contributions to toxicology (1998) and an NSERC Synergy Award (2016). He is a member of the Toxicology Forum. MITCHELL Nicole Dr. Mitchell is an Assistant Research Professor at Michigan State University under the direction of Dr. Felicia Wu. In this position, Dr.Mitchell is responsible for conducting research at the nexus of agriculture and human health with a specialization in mycotoxins. Nicole Mitchell completed a PhD in Integrative Toxicology in 2013 at Texas A&M University, followed by postdoctoral research at Michigan State University in the department of Food Science and Human Nutrition. Her research has focused on aflatoxin and fumonisin remediation strategies in Africa, as well as exposure epidemiology, biomarkers, mycotoxin economics, and mycotoxin-based risk assessment. Dr.Mitchell was awarded the Ruth L. Kirschstein National Postdoctoral Research Fellowship from the National Institute of Environmental Health Sciences in She has served as a member of the Society of Toxicology since 2010 and a member of the Society s Food Safety Specialty Section. MUELLER Utz Dr Utz Mueller is the Principal Toxicologist and Manager of the Risk Assessment Chemical Safety and Nutrition Section in Food Standards Australia New Zealand. Prior to joining FSANZ in 2006 he was the Chief Scientist in the Office of Chemical Safety with responsibility for toxicological assessments of pesticides. Dr Mueller holds a Bachelor of Science (Hons) and PhD in Pharmacology 4 of 6
5 from the University of Western Australia, Perth, WA. Dr Mueller was a Senior Research Fellow at Flinders University in South Australia prior to joining the Therapeutic Goods Administration in 1996 where his primary task was the safety evaluation of pre-market therapeutic drugs. He subsequently joined the Office of Chemical Safety in 1997 to undertake pre-market safety assessments and review the safety of existing agricultural and veterinary chemicals. He has also been a scientific advisor for the FAO/WHO Joint Meeting on Pesticide Residues (JMPR) and Joint Expert Committee of Food Additives (JECFA) for several years. He is currently a JECFA panel member. RILEY Ron Ron Riley is a retired Research Toxicologist (ST15) and former Lead Scientist in the Toxicology and Mycotoxin Research Unit in Athens, Georgia USA. Ron s primary research interest is the mechanism of action of mycotoxins, and in particular fumonisins. Ron continues to serve as an official collaborator with the USDA and continues to work with former collaborators, most notably other research scientists interested in the ongoing fumonisin risk assessment in Guatemala. Ron has served on working groups for the FAO/WHO Joint Expert Committee on Food Additives, the International Programme for Chemical Safety and the International Agency for Research on Cancer. Ron is currently adjunct faculty (since 1982) in the College of Public Health and the College of Pharmacy at the University Of Georgia (UGA). Ron is also faculty in the UGA Interdisciplinary Toxicology Program where he teaches, mentors graduate students, and serves on the Executive Committee. ROUDOT Alain-Claude Dr AC Roudot is Professor in chemical risk assessment at the University of Brest (France). He works for more than 30 years on mathematical modelling for Biology, and specialized in chemical hazard and exposure for 10 years. He is founding director of the Laboratory of Chemical Risk assessment where he directed the biggest study ever done on chemical exposure through cosmetics. His main research areas concerned modelling hazard using BMD and probabilistic approach, analysing the possibilities of evaluating Non Monotonic Dose Response curves, and applying mathematical concepts to exposure evaluation. He is member of French expert committees for 10 years in the areas of cosmetics, food and environmental exposure. He is member of the CONTAM Panel of EFSA since WHEELER Matthew Matthew Wheeler Ph.D is Senior Statistician at the National Institute for Occupational Safety and Health Risk Evaluation Branch. For the past 13 years, his work has focused on creating novel approaches in exposure response modeling as applied to risk assessment, which includes model averaged benchmark dose estimation. He further assists in the different Risk Assessment modeling tasks for Risk Evaluation Branch, which focus on occupational exposures to chemical hazards. He is currently the chair elect for the American Statistical Society s section on risk analysis, and has also consulted with the US EPA about including model averaging methods in their Benchmark Dose Software suite. His current research includes developing Quantitative Structure activity relationship models for in vitro high throughput bioassays, which link exposure to an entire dose-response function. ZANG Yu Dr.Zang is a toxicology reviewer in the office of Food Additive Safety at US FDA, Center for Food Safety and Applied Nutrition (CFSAN). Prior to this position she has worked as a research associate in the Cancer Epidemiology Branch in Jiangsu Institute of Cancer Research, China, and later as a research fellow in the Chemical Hazard Assessment Team in FDA\CFSAN. Dr.Zang graduated from Nanjing University with a B.S degree in Environmental Biology and a M.S. degree specialized in Genetic Toxicology. She earned her Ph.D. in Pharmacology and Toxicology from University of Louisville in 2006, and took a postdoctoral fellowship in the Toxicological Program at Johns Hopkins Bloomberg School of Public Health. Since joining FDA in 2009, Dr.Zang has conducted numerous safety and risk assessments of chemical food contaminants, and is responsible for the toxicology evaluation for direct food additives and color additives regulated by FDA. Dr.Zang has served as a 5 of 6
6 toxicology and risk assessment resource person on several national and international food safety working groups convened by NIH, NTP, FAO and WHO. She is a Diplomat of the American Board of Toxicology. Disclaimer In order to enhance their management of Conflicts of Interest as well as strengthen public trust and transparency in connection with FAO/WHO meetings involving the provision of technical/normative advice, the names and brief biographies of individuals ( Published Information ) being considered for participation in such meetings are disclosed for public notice and comment. The Published Information is provided by the experts themselves and is the sole responsibility of the individuals concerned. FAO/WHO are not responsible for the accuracy, veracity and completeness of the Published Information provided. Furthermore, in no event will FAO/WHO be responsible or liable for damages in relation to the use of, and reliance upon, the Published Information. The comments received by FAO/WHO through the public notice and comment process are treated confidentially and their receipt will be acknowledged through a generic notification to the sender. Comments and perceptions brought to the knowledge of FAO/WHO through this process are an integral component of FAO/WHO s conflict of interest assessment policy and are carefully reviewed. FAO/WHO reserve the right to discuss information received through this process with the relevant expert with no attribution to the provider of such information. Upon review and assessment of the information received through this process, FAO/WHO, in their sole discretion, may take appropriate management action in accordance with their policies. The participation of an expert in a FAO/WHO meeting does not imply that they are endorsed or recommended by the FAO/WHO nor does it create a binding relationship between the expert and FAO/WHO. The list of participating experts, a summary of relevant interests disclosed by such experts, and any appropriate mitigation measures taken by FAO/WHO relating to the management of conflicts of interests, will be reported publically in accordance with FAO/WHO practice. 6 of 6
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