A National Comparison of Total Ankle Replacement Versus Arthrodesis. Is There a Paradigm Shift?

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1 A National Comparison of Total Ankle Replacement Versus Arthrodesis. Is There a Paradigm Shift? Andrew F. Sabour, BS R. Kiran Alluri, MD Eric W. Tan, MD Keck School of Medicine of USC Los Angeles, CA

2 Disclosures I (and/or my coauthors) have no conflicts to disclose. A National Comparison of Total Ankle Replacement Versus Arthrodesis. Is There a Paradigm Shift? Andrew F. Sabour, BS R. Kiran Alluri, MD Eric W. Tan, MD Refer to the AAOS Disclosure Program website. We have no disclosures related to this presentation.

3 Background Total ankle replacement (TAR) and tibiotalar arthrodesis (TTA) are both utilized in the surgical management of ankle osteoarthritis. Surgical techniques and instrumentation have improved and indications for TAR have progressively broadened, leading to a decline in performed TTAs. Procedure preference can vary widely between physicians.

4 Purpose (1) To identify the change in national incidence between TAR and TTA over time. (2) To identify any diagnostic, preoperative, patient, or hospital variables that may lead to a greater preference in either TAR or TTA.

5 Methods 67,974 Treated with TTA or TAR 67,327 Unique procedures 50,156 Age > 50yo 35,096 TTA 15,060 TAR The National Inpatient Sample (NIS) was used for patient data between Procedure filter: Ankle arthrodesis (ICD ) Total ankle replacement (ICD ) Exclusion criteria: Shared arthrodesis & replacement procedures Revision of joint replacement of lower extremity (ICD ) Patients < 50 years of age

6 Methods Univariate analysis compared patient demographics, pre-operative comorbidities, inpatient variables, and hospital variables between success and failure groups. Student s t-test compared continuous variables. Fisher s exact test or Chi-square analysis compared categorical variables. Pre-operative comorbidities with a p-value <0.05 and prevalence >0.5% were included in a logistic regression for multivariate analysis.

7

8 Results Patient variables Arthrodesis (TTA) N = 35,096 Replacement (TAR) N = 15,060 P-value Age 63.7 ± ± 8.68 <0.001 Sex (Female) 17,100 (48.9%) 7,520 (50.0%) Total comorbidities 2.17 ± ± 1.31 <0.001 Anemia 3,950 (11.3%) 778 (5.17%) <0.001 Renal failure 3,110 (8.86%) 424 (2.82%) <0.001 Length of stay 3.43 ± ± 1.41 <0.001 Teaching hospitals 15,100 (58.69%) 4,530 (54.78%) 0.011

9 Temporal analysis demonstrated a significant 15% increase every 3 years in TAR performed from 2007 (14%) to 2013 (45%)

10 Results PRIMARY Diagnosis % TAR ( 07) % TAR ( 13) Increased Odds of Receiving a TAR in 2013 versus 2007 P-value Post-traumatic OA 9.3% 55.5% 12.14x <0.001 Primary OA 25.6% 62.9% 4.93x <0.001 Rheumatoid arthritis 25.5% 51.4% 3.12x <0.001 COMORBID Diagnosis % TAR ( 07) % TAR ( 13) Increased Odds P-value of Receiving a TAR in 2013 versus 2007 DM + HTN + CAD 12.6% 40.3% 4.66x <0.001

11 Conclusions Surgeons are performing TAR with greater frequency. Temporal analysis demonstrated a significant 15% increase every 3 years in TAR performed from 2007 (14%) to 2013 (45%) The largest change from TTA to TAR was with posttraumatic osteoarthritis. As technology has advanced and surgeons have become more facile with the technique, patients with specific comorbidities are undergoing TAR at a significantly higher annual incidence.

12 References 1. Pugely AJ, Lu X, Amendola A, Callaghan JJ, Martin CT, Cram P. Trends in the use of total ankle replacement and ankle arthrodesis in the United States Medicare population. Foot Ankle Int. 2014;35(3): doi: / Terrell RD, Montgomery SR, Pannell WC, Sandlin MI, Inoue H, Wang JC, SooHoo NF. Comparison of practice patterns in total ankle replacement and ankle fusion in the United States. Foot Ankle Int. 2013;34(11): doi: / Stavrakis AI, SooHoo NF. Trends in Complication Rates Following Ankle Arthrodesis and Total Ankle Replacement. J Bone Joint Surg Am. 2016;98(17): doi: /jbjs Bonasia DE, Dettoni F, Femino JE, Phisitkul P, Germano M, Amendola A. Total ankle replacement: why, when and how? Iowa Orthop J. 2010;30: Haddad SL, Coetzee JC, Estok R, Fahrbach K, Banel D, Nalysnyk L. Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis. A systematic review of the literature. J Bone Joint Surg Am. 2007;89(9): doi: /jbjs.f Kim HJ, Suh DH, Yang JH, Lee JW, Kim HJ, Ahn HS, Han SW, Choi GW. Total ankle arthroplasty versus ankle arthrodesis for the treatment of end-stage ankle arthritis: a meta-analysis of comparative studies. Int Orthop. 2017;41(1): doi: /s Pedowitz DI, Kane JM, Smith GM, Saffel HL, Comer C, Raikin SM. Total ankle arthroplasty versus ankle arthrodesis: a comparative analysis of arc of movement and functional outcomes. Bone Jt J. 2016;98-B(5): doi: / x.98b Daniels TR, Younger ASE, Penner M, Wing K, Dryden PJ, Wong H, Glazebrook M. Intermediate-term results of total ankle replacement and ankle arthrodesis: a COFAS multicenter study. J Bone Joint Surg Am. 2014;96(2): doi: /jbjs.l Heckmann N, Bradley A, Sivasundaram L, Alluri RK, Tan EW. Effect of Insurance on Rates of Total Ankle Arthroplasty Versus Arthrodesis for Tibiotalar Osteoarthritis. Foot Ankle Int. 2017;38(2): doi: /

Disclosures. The authors disclosures are in the Final AOFAS Mobile App. The authors may have a potential conflict with this presentation due to:

Disclosures. The authors disclosures are in the Final AOFAS Mobile App. The authors may have a potential conflict with this presentation due to: COFAS Multicenter Study Comparing Ankle Replacement and Ankle Fusion: The effect of Ipsilateral peri-articular deformity and arthritis on Mid-term outcome Murray J. Penner, MD, FRCSC Kevin J. Wing, MD,

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