Using surveillance data to monitor impact of rotavirus vaccine. Lúcia De Oliveira Regional Advisor on New Vaccines IM/PAHO
|
|
- Darren Todd
- 5 years ago
- Views:
Transcription
1 Using surveillance data to monitor impact of rotavirus vaccine Lúcia De Oliveira Regional Advisor on New Vaccines IM/PAHO
2 Main Topics Epidemiological surveillance of rotavirus in American Region Impact studies using surveillance data: el Salvador, Nicaragua and Bolivia Conclusions and recommendations
3 Year of universal introduction of the rotavirus, Region of the Americas, Year Rotavirus 2001 NA 2002 NA 2006 BRA, ELS, EUA, MEX, NIC, PAN, VEN 2007 ECU 2008 BOL 2009 COL, HON, PER, Cayman Islands 2010 GUT, GUY, PAR 2012 DOR- Total 16 countries and 1 territory
4 Estimates of rotavirus diarrhea-associated mortality, 10 Latin American and Caribbean countries, Thi s study W HO estimates Country Population < 5 years of age* Diarrhea deaths, < 5 years of age, 2004 (n) Rotavirus (RV) prevalence among diarrheal hospitalisations (%) RV deaths among children <5 years / year Risk by age 5 years RV deaths R isk by age among 5 years children <5 years / year Bolivia 1,231,245 2, ,057 1 in in 1507 Chile 1, 246, in 415,4 72 <1 0 1 in El Salvador 804, in in 3452 Guatemala Guyana Hondura s Paraguay 1,988,338 2, ,225 1 in in , in in ,131 1, in in , in in 4401 St. Vinc ent 11, no determinado <1 0 1 in 1156 Suriname 46, in in 2307 Venezuela 2, 842,078 1, in in 6641 TOTAL 10,035,941 8, , in ,416 1 in 2937 Fuente: de Oliveira LH, Danovaro-Holliday MC1 Andrus JK, de Fillipis AMB, Gentsch J, Matus CR and Widdowson MA, on behalf of the Rotavirus Surveillance Network. Rotavirus Surveillance in Latin America and the Caribbean JID 2009:200 (Suppl 1) S131
5 Seasonality of hospitalizations for rotavirus infection in Latin American and Caribbean countries in the North Hemisphere (A) and South Hemisphere (B), Fuente: de Oliveira LH, Danovaro-Holliday MC1 Andrus JK, de Fillipis AMB, Gentsch J, Matus CR and Widdowson MA, on behalf of the Rotavirus Surveillance Network. Rotavirus Surveillance in Latin America and the Caribbean JID 2009:200 (Suppl 1) S131
6 Effectiveness of the rotavirus diarrhea in El Salvadorian Children El Salvador: low middle income country in Central America Rotavirus monovalent (RV1) vaccine introduced in October 2006 Methods: case-control study carried out from January 2007-June 2009 Objective: to evaluate effectiveness of the RV1 in children < 5 years old using WHO protocol Cases: identified from 7 hospitals surveillance system Controls: 3 controls for each case (individually matched to the case s date of birth +-30 days) Sentinel surveillance established in Jan. 2006: 7 sentinel hospitals in cities across the country (represent 48% of El Salvador s annual admission for diarrhea in <5 yrs. old) Source: De Palma O, Cruz L, Ramos H; Baires A, Villatoro N, Pastor D, Oliveira L, Kerin T, Bowen M, Gentsch J, Esposito D, Parashar U, Tate J, Patel, M. Effectiveness of rotavirus vaccination against childhood diarrhea in El Salvador: case-control study. BMJ, June 2010: page 1-7.
7 Effectiveness of the rotavirus diarrhea in El Salvadorian Children Effectiveness with 2 doses against diarrhea hospitalizations: 76% (CI: 64%-84%) Effectiveness in children >12 months: 59% (CI: 27%-77%) Effectiveness in children between 6-12 months: 83% (CI:68%-91%) One dose of the vaccine: 51% (CI:26%-67%) Source: De Palma O, Cruz L, Ramos H; Baires A, Villatoro N, Pastor D, Oliveira L, Kerin T, Bowen M, Gentsch J, Esposito D, Parashar U, Tate J, Patel, M. Effectiveness of rotavirus vaccination against childhood diarrhea in El Salvador: case-control study. BMJ, June 2010: page 1-7.
8 Rotavirus vaccine impact study: 7 sentinel hospitals Between Jan and June 2009: 8151 (33.1%) children <5 years old were positive due to RV 98% of the cases were identified during January to June Sentinel hospital surveillance, children under 5 yrs old, January to June, : year % RV + % rv coverage at national level NA (lack of vaccine) Source: De Palma O, Cruz L, Ramos H; Baires A, Villatoro N, Pastor D, Oliveira L, Kerin T, Bowen M, Gentsch J, Esposito D, Parashar U, Tate J, Patel, M. Effectiveness of rotavirus vaccination against childhood diarrhea in El Salvador: case-control study. BMJ, June 2010: page 1-7.
9 RV impact of the vaccine on hospitalized diarrhea, El Salvador. Source: De Palma O, Cruz L, Ramos H; Baires A, Villatoro N, Pastor D, Oliveira L, Kerin T, Bowen M, Gentsch J, Esposito D, Parashar U, Tate J, Patel, M. Effectiveness of rotavirus vaccination against childhood diarrhea in El Salvador: case-control study. BMJ, June 2010: page 1-7.
10 Rotavirus pentavalent vaccine effectiveness study in Nicaragua (June 2007 to June 2008) Nicaragua: low middle income country in Central America (GAVI country) Rotavirus pentavalent (RV5) vaccine introduced in October 2006 Methods: case-control study carried out from June 2007-June 2008 (phase 1) Objective: to evaluate the association between RV5 vaccination and rotavirus hospitalized diarrhea Cases: identified from 4 hospitals through active surveillance ( the sentinel surveillance system started at same time) Controls: hospital and neighborhood individually matched to thecase s date of birth +-30 days Source: Patel, M. Pedreira, C, De Oliveira, L. Association between pentavalent rotavirus vaccine and severe rotavirus diarrhea among children in Nicaragua. JAMA, Jun 3, 2009 Vol. 301, No. 21, p
11 Rotavirus pentavalent vaccine effectiveness study in Nicaragua (June 2007 to June 2008) Effectiveness of all diarrhea that require hospitalization or RHIV= 46% (IC95% = 18% -64%) Effectiveness for severe diarrhea = 58% (IC95% = 30% -74%) Effectiveness for very severe diarrhea = 77%( IC 95% = 39% 92%) Source: Patel, M. Pedreira,C, De Oliveira, L. Association between pentavalent rotavirus vaccine and severe rotavirus diarrhea among children in Nicaragua. JAMA, Juneo 3, 2009 Vol. 301, No. 21, p
12 Effectiveness of the rotavirus diarrhea in Bolivian Children Bolivia: low middle income country in South America (GAVI country) Rotavirus monovalent (RV1) vaccine introduced in August 2008 Methods: case-control study carried out from March 2010-July 2011 Objective: to evaluate effectiveness of the RV1 in children < 5 years old Cases: identified from 6 hospitals surveillance system (sentinel surveillance established in 2006 in cities across the country) Controls: 3 controls for each case (individually matched to the case s date of birth +-30 days) UNPUBLISHED
13 Number of hospitalization for diarrhea among children < 5 yrs. of age and percentage of rotavirus positive samples, 6 sentinel surveillance hospitals, Bolivia, Number/Percen tage Hospitalization due to all causes Hospitalization due to diarrhea Eligible for rotavirus surveillance Enrolled in rotavirus surveillance Rotavirus positive % of rotavirus positive : 2008: vaccine introduction in August
14 Number of diarrhea due to all causes and rotavirus diarrhea, monthly distribution, sentinel hospitals, Bolivia. Number of diarrhea cases NUMERO DE CASOS DE EDAs ROTAVIRUS OTRAS Other CAUSAS causes CASOS cases Months MESES
15 Disease Severity *Vesikari score is a 20-point clinical severity scoring system N = 348 Overnight hospitalization 348 (100%) Vesikari >= (94%) UNPUBLISHED 15
16 Effectiveness by Severity * Vesikari score is a 20-point clinical severity scoring system Num. doses of vaccine Vaccine effectiveness (Vesikari >= 11) 1 dose 45% (CI: 13-65) 2-dose 75% (CI: 61-87) UNPUBLISHED 16
17 Conclusions and Recommendations Strengthen epidemiological surveillance through regional and global networks; evaluate the impact, monitor the prevalence of circulating strains, identify changes in the epidemiological profile Strengthen laboratory networks for new vaccines and the coordination between epidemiology and laboratory Report quality data systematically: regional profile, differences and similarities between countries, develop a software * WER, N 23 5 June 2009 (SAGE May 2009)
18 Conclusions and Recommendations Integrate the surveillance of rotavirus and bacterial pneumonia/meningitis Promote special studies: determine effectiveness, safety, protection with incomplete schedules, risk factors that can affect effectiveness Share new vaccines introduction and surveillance experiences. This will help other countries identify weaknesses and strengths as they implement in their countries
19 Thank you!
Monitoring For Rotavirus Serotypes In The Americas. Jon Gentsch
Monitoring For Rotavirus Serotypes In The Americas Jon Gentsch Centers for Disease Control and Prevention, Atlanta, USA * The findings and conclusions in this presentation are those of the authors and
More informationdeveloping countries in Latin America?
. How have rotavirus vaccines worked in developing countries in Latin America? Brendan Flannery, Pan American Health Organization, Brazil and Lúcia De Oliveira, Immunization Unit/FCH, Washington, DC 9th
More informationProgress Toward Rubella and Congenital Rubella Syndrome Elimination in the Western Hemisphere,
1 Introduction: Progress Toward Rubella and Congenital Rubella Syndrome Elimination in the Western Hemisphere, 2003-2008 1 Enhanced measles elimination activities in the Region of the Americas during the
More informationIntroduction of New Vaccines in Latin America and the Caribbean: Decision-Making LUCIA HELENA DE OLIVEIRA AND BARBARA JAUREGUI
Introduction of New Vaccines in Latin America and the Caribbean: Decision-Making LUCIA HELENA DE OLIVEIRA AND BARBARA JAUREGUI 2 Introduction of New Vaccines in Latin America and the Caribbean: Decision-Making
More informationSustaining Immunization in Developing Countries: The Future We Make
Sustaining Immunization in Developing Countries: The Future We Make Global Health Summit Denver, CO 29 April 211 Jon Kim Andrus, MD Deputy Director Umbrella of protection in the Americas Measles eradication
More informationVaccines against Rotavirus & Norovirus. Umesh D. Parashar CDC, Atlanta, GA
TM Vaccines against Rotavirus & Norovirus Umesh D. Parashar CDC, Atlanta, GA 1 Rotavirus is the Leading Cause Of Severe Diarrhea in Children
More informationWORLD RADIOLOGY DAY 2013
WORLD RADIOLOGY DAY 2013 RADIOLOGY: FACING SOME MAJOR PUBLIC HEALTH CHALLENGES IN LAC: CANCER, CVDS, TB, MATERNAL AND INFANT MORTALITY November 8, 2013. Washington DC. USA Branka Legetic, Unit Chief a.i.,
More informationRotavirus vaccine impact on diarrhea associated child mortality, hospital admissions & clinical visits in Bolivia
Rotavirus vaccine impact on diarrhea associated child mortality, hospital admissions & clinical visits in Bolivia Lucia Inchauste, Nataniel Mamani, Sonia Jimenez, Raul Montesano, Maritza Patzi, Rita Revollo,
More informationDr Michelle Groome MBBCh (Wits) DCH(SA) MScMed (Epi & Biostats) Department of Science and Technology/National Research Foundation: Vaccine
Dr Michelle Groome MBBCh (Wits) DCH(SA) MScMed (Epi & Biostats) Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases; Medical Research Council: Respiratory and
More informationGisele Almeida Public Policies, Regulation, and Health Financing Health Systems and Services
Gisele Almeida Public Policies, Regulation, and Health Financing Health Systems and Services Challenges to the Health Sector External Context Complexity of health determinants Multiplicity of initiatives
More informationConclusions and Recommendations of the Experts Meeting on Rotavirus Genotypes in the Region of the Americas
Conclusions and Recommendations of the Experts Meeting on Rotavirus Genotypes in the Region of the Americas Eyal Leshem December 9, 2013 National Center for Immunization & Respiratory Diseases Division
More informationRotavirus vaccines: Issues not fully addressed in efficacy trials
Rotavirus vaccines: Issues not fully addressed in efficacy trials TM Umesh D. Parashar Lead, Viral Gastroenteritis Team CDC, Atlanta, USA uparashar@cdc.gov 1 Two New Rotavirus Vaccines Licensed in 2006
More informationRotavirus Vaccines. Gagandeep Kang Christian Medical College Vellore
Rotavirus Vaccines Gagandeep Kang Christian Medical College Vellore Rotavirus disease burden Rotavirus vaccines and candidates Performance of vaccines in developed and developing countries Longitudinal
More informationPandemic (H1N1) (August 28, h GMT; 12 h EST) Update on the qualitative indicators
Regional Update Pandemic (H1N1) 29 (August 28, 29-17 h GMT; 12 h EST) Update on the qualitative indicators For Epidemiological Week 33 (EW 33), from 16 August to 22 August, 22 countries reported updated
More informationIntroduction to the ProVac Initiative
Introduction to the ProVac Initiative E-toolkit training module Nathalie El Omeiri, PAHO/WHO, Washington D.C. Family, Health Promotion and Life Course, Immunization unit, elomeirin@paho.org Contents of
More informationCurrent Status on the implementation of TB- HIV collaborative activities in the Americas. Results of a survey in the countries of the Region
Current Status on the implementation of TB- HIV collaborative activities in the Americas Results of a survey in the countries of the Region 2012 1 Acknowledgements We would like to express our gratitude
More informationRegional Update Influenza (August 16, h GMT; 12 h EST)
Regional Update Influenza (August 16, 21-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National Influenza
More informationStrengthening evidence-based decision making for new vaccine introduction: PAHO s ProVac Initiative
http://www.paho.org/provac Strengthening evidence-based decision making for new vaccine introduction: PAHO s ProVac Initiative Cara Bess Janusz Immunization, PAHO 1 st Regional Dengue Symposium 3-4 November
More informationRegional Update Pandemic (H1N1) 2009 (July 19, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 9 (July 19, - 17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National Influenza
More informationEffect of Rotavirus Vaccination on Death from Childhood Diarrhea in Mexico
original article Effect of Rotavirus Vaccination on Death from Childhood Diarrhea in Mexico Vesta Richardson, M.D., Joselito Hernandez-Pichardo, M.D., Manjari Quintanar-Solares, M.D., Marcelino Esparza-Aguilar,
More informationRegional Update Pandemic (H1N1) 2009
Regional Update Pandemic (H1N1) 2009 (September 18, 2009-22 h GMT; 17 h EST) Update on the Qualitative Indicators For Epidemiological Week 36 (EW 36), from 6 September to 12 September, 17 countries reported
More information. /////////////////// /////////////////// / Berenice? . BLOOD HEPATITIS B HEPATITIS C HIV T. pallidum T. cruzi TRANSFUSION HOST The Southern Cone Initiative, 1991 The Ministers of Health of Argentina,
More informationRotavirus Vaccine Impact and Effectiveness in Armenia and Moldova
Rotavirus Vaccine Impact and Effectiveness in Armenia and Moldova Margaret M. Cortese, MD Centers for Disease Control and Prevention 12 th International Rotavirus Symposium, Melbourne, AUST Sept. 7, 2016
More informationEffectiveness of monovalent rotavirus vaccine in the Philippines 13 th Rotavirus Symposium, 29 Aug 2018, Minsk, Belarus
Effectiveness of monovalent rotavirus vaccine in the Philippines 13 th Rotavirus Symposium, 29 Aug 2018, Minsk, Belarus Anna Lena Lopez, MD, MPH Director, Institute of Child Health and Human Development,
More informationValue of post-licensure data to assess public health value Example of rotavirus vaccines
Value of post-licensure data to assess public health value Example of rotavirus vaccines TM Umesh D. Parashar Lead, Viral Gastroenteritis Team CDC, Atlanta, USA uparashar@cdc.gov 1 Two New Rotavirus Vaccines
More informationRegional Update Pandemic (H1N1) 2009 (July 6, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 29 (July 6, 21-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National Influenza
More informationPandemic (H1N1) (August 14, h GMT; 12 h EST) Update on the Qualitative Indicators
Regional Update Pandemic (H1N1) 2009 (August 14, 2009-17 h GMT; 12 h EST) Update on the Qualitative Indicators For epidemiological week 31 (EW 31, August 2 to August 8) 17 countries have reported updated
More informationCatching-up with pentavalent vaccine: Exploring reasons behind lower rotavirus vaccine coverage in El Salvador
Catching-up with pentavalent vaccine: Exploring reasons behind lower rotavirus vaccine coverage in El Salvador Eduardo Suarez-Castaneda, Ministry of Health, El Salvador Eleanor Burnett, Emory University
More informationRegional Update Pandemic (H1N1) 2009 (May 24, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 2009 (May 24, 2010-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National
More informationRegional Update Pandemic (H1N1) 2009
Regional Update Pandemic (H1N1) 2009 (September 04, 2009-22 h GMT; 17 h EST) Update on the Qualitative Indicators For Epidemiological Week 34 (EW 34), from 23 August to 29 August, 20 countries reported
More informationDR. CLAUDINA E. CAYETANO REGIONAL MENTAL ADVISOR Pan-American Health Organization/ World Health Organization
DR. CLAUDINA E. CAYETANO REGIONAL MENTAL ADVISOR Pan-American / World Outline Facts and Figures Suicide a major Public problem Suicide in the Americas Risk and Protective factors and related interventions
More informationHepatitis B and C in the Spotlight: A public health response in the Americas. Key Messages
2017 highlights Hepatitis B and C in the Spotlight: A public health response in the Americas Key Messages Regarding the national structures developed to support the response to the viral hepatitis epidemics,
More informationRegional Update EW 41 Influenza (October 25, h GMT; 12 h EST)
Regional Update EW 41 Influenza (October 2, 21-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National Influenza
More informationRegional Update Pandemic (H1N1) 2009 (January 19, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 2009 (January 19, - 17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National
More informationRESEARCH. Effectiveness of rotavirus vaccination against childhood diarrhoea in El Salvador: case-control study
1 Ministerio de Salud, San Salvador, El Salvador 2 PanAmerican Health Organization, San Salvador 3 PanAmerican Health Organization, Washington, DC, USA 4 Viral Gastroenteritis Team, Epidemiology Branch,
More informationUpdate on Pentavalent Human-Bovine Rotavirus Vaccine. Michelle Goveia, MD, MPH Medical Director MSD Vaccines India, September 2014
Update on Pentavalent Human-Bovine Rotavirus Vaccine Michelle Goveia, MD, MPH Medical Director MSD Vaccines India, September 2014 Outline Characteristics of RotaTeq and its worldwide use Recent data evaluating
More informationRegional Update Pandemic (H1N1) 2009 (December 1, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 2009 (December 1, 2009-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National
More informationRubella and CRS Elimination in the Americas
Rubella and CRS Elimination in the Americas Jon Kim Andrus, MD Deputy Director, PAHO Rome, Italy 8-10 February 2012 Presentation Opportunities for a rubella elimimation initiative The impact of the initiative
More information50th DIRECTING COUNCIL 62nd SESSION OF THE REGIONAL COMMITTEE
PAN AMERICAN HEALTH ORGANIZATION WORLD HEALTH ORGANIZATION 50th DIRECTING COUNCIL 62nd SESSION OF THE REGIONAL COMMITTEE Washington, D.C., USA, 27 September-1 October 2010 Provisional Agenda Item 4.10
More informationRegional Update Pandemic (H1N1) 2009 (March 15, h GMT; 12 h EST)
Regional Update Pandemic (H1N1) 2009 (March 15, 2010-17 h GMT; 12 h EST) The information contained within this update is obtained from data provided by Ministries of Health of Member States and National
More informationRotavirus vaccine impact
Rotavirus vaccine impact Introduction. Rotavirus vaccines lead to significant reductions in severe and fatal diarrhea in both vaccinated and unvaccinated children Rotavirus vaccines are saving lives and
More informationInfluenza Vaccine Use In the Americas
Influenza Vaccine Use In the Americas Network for Evaluation of Influenza Vaccine Effectiveness REVELAC-i Alba Maria Ropero-Alvarez Comprehensive Family Immunization Unit PAHO/FGL/IM Global Vaccine and
More informationOVERVIEW OF THE POLIO ERADICATION AND ENDGAME STRATEGIC PLAN AND THE topv TO bopv SWITCH
OVERVIEW OF THE POLIO ERADICATION AND ENDGAME STRATEGIC PLAN AND THE topv TO bopv SWITCH Dr. Karen Lewis-Bell Advisor, Immunization Switch Monitoring Training Jamaica, December 9, 2015 Presentation Outline
More informationMarta-Louise Ackers, a Robert E Quick, a Christopher J Drasbek, b Lori Hutwagner c and Robert V Tauxe a
O International Epldemiological Association 998 Printed in Great Britain International Journal of Epidemiology 998:27:-4 Are there national risk factors for epidemic cholera? The correlation between socioeconomic
More informationUS Rotavirus Vaccination Program
US Rotavirus Vaccination Program 1 Rotavirus Vaccines in US Feb 2006 Feb 2006 April 2008 June 2008 RotaTeq licensed by FDA RotaTeq recommended by ACIP Rotarix licensed by FDA ACIP to consider Rotarix 2
More informationDr. Bernd Benninghoff GSK Vaccines, GML Global Medical Affairs Director
ROTARIX the human rotavirus vaccine: -is applied in a 2-dose schedulecompletes the course at the earliest possible age, prevents morbidity and mortality from RV GE regardless of the circulating strains
More informationTaking vaccine effectiveness into public health decision making: The ProVac Example
http://www.paho.org/provac Taking vaccine effectiveness into public health decision making: The ProVac Example Evaluating dengue effectiveness workshop June 12 th, 2014 Washington, DC Cara Bess Janusz
More informationSafety of the Blood Supply in Latin America
CLINICAL MICROBIOLOGY REVIEWS, Jan. 2005, p. 12 29 Vol. 18, No. 1 0893-8512/05/$08.00 0 doi:10.1128/cmr.18.1.12 29.2005 Copyright 2005, American Society for Microbiology. All Rights Reserved. Safety of
More informationMain developments in past 24 hours
ECDC DAILY UPDATE Pandemic (H1N1) 2009 Update 02 October 2009, 09:00 hours CEST Main developments in past 24 hours Weekly Influenza Surveillance Overview to be published today; Media highlights and Eurosurveillance
More informationRoger I. Glass, M.D., Ph.D. Director, Fogarty International Center Associate Director for International Research, NIH
Rotavirus Vaccines: Prioritization for Introductions- National & International Case Studies Fondation Merieux Conference Center November 27, 2012 Roger I. Glass, M.D., Ph.D. Director, Fogarty International
More informationImpact of Rotavirus Vaccination on Diarrheal Hospitalizations in Children Aged <5 Years in Lusaka, Zambia
Clinical Infectious Diseases SUPPLEMENT ARTICLE Impact of Rotavirus Vaccination on Diarrheal Hospitalizations in Children Aged
More informationPAHO WORKSHOP ON CERVICAL CANCER PREVENTION STRATEGIES USING VIA SCREENING AND CRYOTHERAPY TREATMENT
PAHO WORKSHOP ON CERVICAL CANCER PREVENTION STRATEGIES USING VIA SCREENING AND CRYOTHERAPY TREATMENT As part of the activities for implementing the Regional Strategy and to promote the new approaches for
More informationEdwin J. Asturias Associate Director
Edwin J. Asturias Associate Director Center for Global Health Associate Professor of Pediatrics and Epidemiology Effectiveness Dengue Vaccine Washington DC, June 2014 UNIVERSITY OF COLORADO COLORADO STATE
More informationPANORAMA OF FOOD AND NUTRITIONAL SECURITY IN LATIN AMERICA AND THE CARIBBEAN
217 PANORAMA OF FOOD AND NUTRITIONAL SECURITY IN LATIN AMERICA AND THE CARIBBEAN PROLOGUE FOREWORD The Panorama of food and nutritional security in Latin America and the Caribbean 217, published by the
More informationRegional Update Pandemic (H1N1) 2009 (July 31, h GMT; 17 h EST) Update on the Qualitative Indicators Epidemiological Week 29 intensity
Regional Update Pandemic (H1N1) 2009 (July 31, 2009-22 h GMT; 17 h EST). Update onn thhe t Quual lli iit tati iivve InndiI iicatorss As of Epidemiological Week 29 (EW 29, July 19 to 25) all the 35 countries
More informationGSK VACCINES: KEY GROWTH DRIVERS
GSK VACCINES: KEY GROWTH DRIVERS Martin Andrews Senior Vice President, Global Vaccines Centre of Excellence, GSK Biologicals Millions of children die from infectious diseases Many of these deaths are preventable
More informationConsiderations for Introduction of a Rotavirus Vaccine in Oman: Rotavirus Disease and Economic Burden
SUPPLEMENT ARTICLE Considerations for Introduction of a Rotavirus Vaccine in Oman: Rotavirus Disease and Economic Burden S. A. Al Awaidy, 1 S. Bawikar, 1 S. Al Busaidy, 2 S. Baqiani, 2 I. Al Abedani, 1
More informationSenior Management Team Meeting Target setting in Latin America
Senior Management Team Meeting Target setting in Latin America October 2006 Nancy Andrade-Castro RST Latin America Geneva/2006 For all enquiries, please contact Nancy Andrade-Castro, Acting Director for
More informationProgress Made in the Integration of EPI Costing and Planning
Volume XXXV Number 5 Immunize and Protect Your Family October 2013 Progress Made in the Integration of EPI Costing and Planning If we compare the situation of the Expanded Program on Immunization (EPI)
More informationCase study: Evaluation of Rotavirus vaccine impact and safety following introduction into the national immunizations programme of Sudan
15 th ADVAC Case study Rota in Sudan Case study: Evaluation of Rotavirus vaccine impact and safety following introduction into the national immunizations programme of Sudan Background Rotavirus is one
More informationRotavirus serotype surveillance: Results and experiences in Tanzania. Adolfine Hokororo. KPA Vaccinology Symposium- 29 th April
Rotavirus serotype surveillance: Results and experiences in Tanzania Adolfine Hokororo KPA Vaccinology Symposium- 29 th April 2016 1 outline 1. Introduction-burden of RVGE 2. goals of RVGE sentinel surveillance
More informationREVELAC-i: Progress in measuring influenza vaccine effectiveness in Latin America and way forward
REVELAC-i: Progress in measuring influenza vaccine effectiveness in Latin America and way forward SARInet annual meeting, Punta Cana, May 23 2017 Nathalie El Omeiri On behalf of REVELAC-i network, Alba
More informationZika Operation: IMPACT IN THE AMERICAS. Americas Regional Office
Zika Operation: IMPACT IN THE AMERICAS Americas Regional Office WHAT IS the Zika Operation in the Americas? The Zika Operation works to: Support National Societies in responding to the outbreak and implementing
More informationRegional Immunization Action Plan for the Americas Progress report 2015
Regional Immunization Action Plan for the Americas Progress report 2015 Introduction During the 54th Directing Council meeting of the Pan American Health Organization (PAHO) in September 2015, Member States
More informationReduction in morbidity and mortality from childhood diarrhoeal disease after species A rotavirus vaccine introduction in Latin America A Review
Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 106(8): 907-911, December 2011 907 Reduction in morbidity and mortality from childhood diarrhoeal disease after species A rotavirus vaccine introduction in Latin
More informationLessons Learned and Best Practices of Achieving and Maintaining Measles and Rubella Elimination in the Americas
Lessons Learned and Best Practices of Achieving and Maintaining Measles and Rubella Elimination in the Americas Jon Kim Andrus, MD Deputy Director, PAHO Rome, Italy 8-10 February, 2012 Presentation Outline
More informationRotavirus Vaccines for Infants in Developing Countries in Africa and Asia: Considerations from a World Health Organization Sponsored Consultation
SUPPLEMENT ARTICLE Rotavirus Vaccines for Infants in Developing Countries in Africa and Asia: Considerations from a World Health Organization Sponsored Consultation A. Duncan Steele, 1,2 Manish Patel,
More informationFINAL REPORT TECHNICAL ADVISORY GROUP ON VACCINE-PREVENTABLE DISEASES AUGUST 2009, COSTA RICA
TECHNICAL ADVISORY GROUP ON VACCINE-PREVENTABLE DISEASES 24-26 AUGUST 2009, COSTA RICA FINAL REPORT XVIII TAG MEETING, COSTA RICA, 2009 DRAFT FINAL REPORT (2 SEPTEMBER) 1 TECHNICAL ADVISORY GROUP ON VACCINE-PREVENTABLE
More informationSustained Reduction of Childhood Diarrhea-Related Mortality and Hospitalizations in Mexico After Rotavirus Vaccine Universalization
Clinical Infectious Diseases SUPPLEMENT ARTICLE Sustained Reduction of Childhood Diarrhea-Related Mortality and Hospitalizations in Mexico After Rotavirus Vaccine Universalization Edgar Sánchez-Uribe,
More informationRegional Update EW 44 Influenza (November 15, h GMT; 12 h EST)
Regional Update EW 44 Influenza (November 15, 2011-17 h GMT; 12 h EST) PAHO interactive influenza data: http://ais.paho.org/phip/viz/ed_flu.asp Influenza Regional Reports: www.paho.org/influenzareports
More informationASSESSMENT OF IMPACTS OF AIR POLLUTION ON HEALTH
ASSESSMENT OF IMPACTS OF AIR POLLUTION ON HEALTH Michal Krzyzanowski WHO ECEH Bonn Office 1 Exposure - Response Population X Exposure IMPACT ESTIMATE FOR POPULATION X Population X health status WHO Air
More informationRotavirus: WHO Global Recommendations, Policy, and Surveillance
Rotavirus: WHO Global Recommendations, Policy, and Surveillance 9 th International Rotavirus Symposium 2 August 2010 Mary Agócs, MD, MSc Department of Immunization, Vaccines & Biologicals From 1999 2009:
More information_flu.asp. region States. North. The Caribbean and. South. region. South
Regional Update EW 48, 2013 Influenza and other respiratory viruses (December 11, 2013) PAHO interactive influenza data: Uhttp://ais.paho.org/phip/viz/ed flu.asp Influenza Regional Reports: www.paho.org/reportesinfluenza
More informationXXVI CINP CONGRESS. mood disorders: The application. Gerhard Heinze M.D.
XXVI CINP CONGRESS CINP Task Force: Antidepressants and mood disorders: The application The impact of antidepressants and the treatment of depression in Latin America Gerhard Heinze M.D. Life expectancy
More informationSpecial Topic. The ten leading causes of death in countries of the Americas
The ten leading causes of death in countries of the Americas Table 1: Country specific information on the ten leading causes of death in broad age groups, by sex, for the latest two or three data years
More informationChallenges for Latin America s. Information on Drug Consumption
Challenges for Latin America s Information on Drug Consumption Fatima Marinho, MD, MPH, PHD Coordinator of Information and Health Analysis - PAHO International Day against Drug Abuse & Illicit Trafficking
More informationFOURTH ANNUAL VACCINATION WEEK IN THE AMERICAS (VWA 2006) FINAL REPORT
Immunization Unit Community and Family Health Area FOURTH ANNUAL VACCINATION WEEK IN THE AMERICAS (VWA 2006) FINAL REPORT 22-29 April 2006 Background Vaccination Week in the Americas (VWA) is an initiative
More informationGlobal Vaccine Action Plan
Global Vaccine Action Plan Regional reports on progress towards GVAP RVAP goals Annex to the GVAP Secretariat Annual Report 2016 World Health Organization 2016 All rights reserved. Publications of the
More informationImmunization Newsletter
Immunization Newsletter Pan American Health Organization Volume XXXV Number 4 Immunize and Protect Your Family August 2013 XXI Meeting of PAHO s Technical Advisory Group (TAG) on Vaccine-preventable Diseases:
More informationr 5 PAN AMERICAN WORLD HEALTH
directing council regional committee r 5 PAN AMERICAN WORLD HEALTH HEALTH ORGANIZATION ORGANIZATION XXXV Meeting Washington, D.C. September 1991 XLIII Meeting Provisional Agenda Item 5.3 CD35/15 16 July
More informationGSK Medicine: Study No.: Title: Rationale: Study Period Objectives: Indication: Study Investigators/Centers: Research Methods: Data Source:
The study listed may include approved and non-approved uses, formulations or treatment regimens. The results reported in any single study may not reflect the overall results obtained on studies of a product.
More informationRegional Update EW 31, 2014 Influenza and other respiratory viruses (August 12, 2014)
Regional Update EW 31, 2014 Influenza and other respiratory viruses (August 12, 2014) PAHO interactive influenza data: Uhttp://ais.paho.org/phip/viz/ed_flu.asp Influenza Regional Reports: www.paho.org/influenzareports
More informationDoes Rota Vaccine Reduce Attacks of Acute Gastroenteritis among Children Under 15 Months of Age?
International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 10 (2017) pp. 1178-1184 Journal homepage: http://www.ijcmas.com Original Research Article https://doi.org/10.20546/ijcmas.2017.610.142
More informationDecline in Diarrhea Mortality and Admissions after Routine Childhood Rotavirus Immunization in Brazil: A Time-Series Analysis
Decline in Diarrhea Mortality and Admissions after Routine Childhood Rotavirus Immunization in Brazil: A Time-Series Analysis Greice Madeleine Ikeda do Carmo 1, Catherine Yen 2,3, Jennifer Cortes 2,3,
More informationAccelerating the Introduction of Rotavirus Vaccines into GAVI-Eligible Countries
Accelerating the Introduction of Rotavirus Vaccines into GAVI-Eligible Countries Investment Case for GAVI Secretariat Submitted by PATH s Rotavirus Vaccine Program in collaboration with WHO and the US
More informationCurrent Status in Latin America
WHO International Consultation 15 to 17 October 2014 Munich, Germany JUSTIFICATION OF THE USE OF CT FOR INDIVIDUAL HEALTH ASSESSMENT OF ASYMPTOMATIC PEOPLE Current Status in Latin America Gloria Soto Giordani
More informationcountries do not have information available for this indicator.
Regional Update Pandemic (H1N1) 2009 (July 22, 2009-22 h GMT; 17 h EST) The data and information in this report will be updated on a weekly basis and available at: http://new.paho.org/hq/index.php?option=com_content&task=blogcategory&id=814&itemid=1206
More information24 April to 1 May 2010 Final Report
24 April to 1 May 2010 Final Report Comprehensive Family Immunization Family and Community Health Area Background The eighth celebration of Vaccination Week in the Americas (VWA) took place from 24 April-1
More information20. The purpose of this document is to examine the pre-pandemic efforts and the response to the new influenza A (H1N1) virus since April 2009.
B. UPDATE ON THE PANDEMIC (H1N1) 2009 CD50/INF/6 (Eng.) - 7 - Annex B Background 20. The purpose of this document is to examine the pre-pandemic efforts and the response to the new influenza A (H1N1) virus
More informationUpdate on Transition: the case of Honduras. Minister Dra Yolani Batres AMRO/EURO Gavi Constituency Representative Geneva June 2016
Update on Transition: the case of Honduras Minister Dra Yolani Batres AMRO/EURO Gavi Constituency Representative Geneva June 2016 GAVI Support for Honduras Content Honduras EPI Situation 2011-2016 Vaccination
More informationVaccine Hesitancy: Acceptance and demand of vaccines in the Americas
Vaccine Hesitancy: Acceptance and demand of vaccines in the Americas Desiree Pastor, MD, MPH Regional Immunization Advisor Immunization Unit Department of Family, Gender and Life Course PAHO/WHO Outline
More information50th DIRECTING COUNCIL 62nd SESSION OF THE REGIONAL COMMITTEE
PAN AMERICAN HEALTH ORGANIZATION WORLD HEALTH ORGANIZATION 50th DIRECTING COUNCIL 62nd SESSION OF THE REGIONAL COMMITTEE Washington, D.C., USA, 27 September-1 October 2010 Agenda Item 4.17 27 September
More informationChanges in Childhood Diarrhea Incidence in Nicaragua Following 3 Years of Universal Infant Rotavirus Immunization
ORIGINAL STUDIES Changes in Childhood Diarrhea Incidence in Nicaragua Following 3 Years of Universal Infant Rotavirus Immunization Sylvia Becker-Dreps, MD, MPH,* Margarita Paniagua, MS, Rosalie Dominik,
More informationEradication of Wild Poliovirus from the Americas: Acute Flaccid Paralysis Surveillance,
S37 Eradication of Wild Poliovirus from the Americas: Acute Flaccid Paralysis Surveillance, 1988-1995 Ciro A. de Quadros, Bradley S. Hersh, Jean-Marc Olive, Jon K. Andrus, Claudio M. da Silveira, and Peter
More informationA Human Rotavirus Vaccine
7th International Rotavirus Symposium Lisbon, Portugal, 12-13 June 2006 A Human Rotavirus Vaccine Dr. Béatrice De Vos GlaxoSmithKline Biologicals Rixensart, Belgium Rotarix is a trade mark of the GlaxoSmithKline
More informationPopulation effectiveness of the pentavalent and monovalent rotavirus vaccines: a systematic review and meta-analysis of observational studies
Hungerford et al BMC Infectious Diseases (2017) 17:569 DOI 101186/s12879-017-2613-4 RESEARCH ARTICLE Population effectiveness of the pentavalent and monovalent rotavirus vaccines: a systematic review and
More informationHPV Vaccines: Background and Current Status
HPV Vaccines: Background and Current Status Bogota, Colombia, 2007 Jon Kim Andrus, MD HPV and Cervical Cancer Evidence that HPV is essential: Documented molecular studies of cervical cancer Case-control
More informationAssessing the Evidence for Potential Benefits and Risks of Removing the Age Restrictions for Rotavirus Vaccination
Assessing the Evidence for Potential Benefits and Risks of Removing the Age Restrictions for Rotavirus Vaccination Manish Patel SAGE Geneva 12 April 2012 1 Overview! Update new inputs for benefit risk
More informationEfforts at Rubella Elimination in the United States: The Impact of Hemispheric Rubella Control
SUPPLEMENT ARTICLE Efforts at Rubella Elimination in the United States: The Impact of Hemispheric Rubella Control Gustavo H. Dayan, 1 Carlos Castillo-Solórzano, 2 Margarita Nava, 3 Bradley S. Hersh, 4
More information