introducing Swift the breakthrough treatment for stubborn warts & verruca
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- Edwina Owen
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1 introducing Swift the breakthrough treatment for stubborn warts & verruca
2 SWIFT PRESENTATION OVERVIEW - Emblation/AMT Surgical overview - what is microwave ablation - swift overview - scientific/clinical overview - patient cases
3 EMBLATION WE MAKE WAVES Emblation has achieved substantial recognition worldwide for pioneering advances in the rapidly growing field of medical microwave technology Founded in 2007 in US, relocated HQ to Central Scotland in Q Support for research activities in numerous fields of medicine from: SMART:Scotland - Technology Feasibility, Research & Development Bio-innovate HPV and Cardiology based research using MW Cancer Research UK cancer based research using MW Projects, partnerships and relationships with multiple universities and teaching hospitals (including but not limited to, Golden Jubilee National Hospital, Southampton General Hospital, Ninewells Hospital) developing new treatments Major design & manufacturing contracts with global medical leaders including: world leader in energy based ablation therapy for cancer world leader in robotic based surgery
4 EMBLATION AWARD WINNING TECHNOLOGY British Engineering Excellence Awards 2017 Highly Commended, Small Business of the Year Business Insider Made in Scotland Awards 2017 Awarded, Product of the Year Scottish Life Sciences Awards 2017 Awarded, Innovative Collaboration The Clacks Awards 2017 Awarded, Outstanding Performance PWC UK Private Business Awards 2017 Finalist, Business of the Year CFPM Awards 2016 Awarded, Best Use of Innovation & Technology British Engineering Excellence Awards 2016 Highly Commended, Small Business of the Year The Clacks Awards 2016 Awarded, Outstanding Performance Business Inside Made in Scotland Awards 2016 Awarded, Innovator of the Year British Small Business Awards 2016 Finalist, Innovation of the Year
5 AMT SURGICAL MISSION STATEMENT It is our goal to be the leading supplier of healthcare technology systems in Canada by providing customer focused surgical and clinical solutions. AMT Surgical accomplishes this through careful consultation with our customers to determine the optimum balance of patient safety, clinical performance, ease of use and cost effectiveness. We look to our suppliers as focused solution partners. We add value to our superior product solutions by providing knowledgeable representation, friendly and efficient customer service, and innovative educational support to all of our customers. It is integral to our mission to continually seek innovations that will help make us the first choice as the Canadian supplier of clinical and medical supplies.
6 AMT SURGICAL - FORMATION & EXPANSION Optimizing our approach to healthcare technology delivery in Canada 1994 AMT was founded by Bill Roberts & Bruce MacDonald 1999 Awarded Medbuy Contract 2003 SARS Epidemic NO access to Operating Rooms across Canada AMT manufactures masks in-house 2006 AMT Endoscopy was founded 2009 H1N1 Epidemic 2012 Secured Allen Medical line of Patient Positioning Products Secured Symmetry Surgical line of Surgical Instruments 2016 Vantage sells off all Medivatorsrelated assets to allocate increased focus to the clinical arena. Operational, Finance, and HR functions are merged with AMT in Kitchener Secured the ERBE line of Specialized Equipment & Accessories Secured IC Medical line of Smoke Evacuators and Accessories Secured the Megadyne line of Electrosurgical Products including the revolutionary reusable Megadyne Patient Return Electrode Secured the Microline line of Laparoscopic Instrumentatio n Acquisition by Diploma PLC Diploma acquires Carsen Medical, one of Canada s oldest and most well known distributors and merges it with AMT Endoscopy to form Vantage AMT celebrates 20 Years of being one of Canada s leading Healthcare Providers Vantage signs Richard Wolf to a long-term exclusive distribution agreement in Canada. Two distinct divisions are created, one focusing on GI and the other on MIS.
7 what is microwave ablation?
8 SWIFT WHAT IS MICROWAVE ABLATION? microwave ablation First research published in 1980s Japanese researchers described a method of treating liver tumours (tested since 1970s) 80% of liver cancer patients not eligible for surgery < 100,000 procedures / year NICE approved Indicated for tumours in the lung, liver, kidney, breast, bone; also used in AF tx, urology procedures & pain management image credit: University of Hong Kong
9 SWIFT WHAT IS MICROWAVE ABLATION? Every Day Uses Microwave oven Bluetooth applications Mobile phones Wifi GPS Satellite comms systems Radar
10 SWIFT HOW DOES IT WORK? image credit: Dr Ivan Bristow
11 swift overview
12 SWIFT THE BREAKTHROUGH TREATMENT FOR COMMON AND PLANTAR WARTS Launched in 2016, Swift is one of the fastest growing treatments in Podiatry. With treatment times in seconds, the award-winning Swift system harnesses the power of microwave energy to give Podiatrists a new, precise, and easy way of treating plantar warts. 4 key differences that Swift offers: Confidence independent clinical study headed by UK Podiatrist Dr Ivan Bristow revealed 76% efficacy in the worst cases of verruca (University of Southampton, 3 centre study; corroborated by Post Market Follow-up data comprising 1,205 patients) Consistency a repeatable treatment with predictable clinical outcomes Cleanliness no smoke, no anaesthetic, no post-procedural dressing and minimal debridement Convenience the potential for much shorter appointment times (average Swift follow-up tx time is 15 minutes); widely acknowledged anecdotal evidence that verruca in children resolve very quickly
13 SWIFT THE EQUIPMENT The Swift system is comprised of a compact, microwave generator (9lbs), a flexible microwave cable, and a handpiece. Users set time and power, ensure surface contact, and press a button on the handpiece to activate power. Swift also features a disposable applicator tip, with one disposable required per patient visit. To prevent cross-contamination, the tip expires after 15 minutes and has a unique, re-use mitigation feature included in the design.
14 SWIFT UK LOCATIONS Q clinics 330 trained users >20,000 treatments in the UK since OCT/2016
15 scientific/clinical overview
16 SWIFT THE SCIENCE BEHIND SWIFT Swift is a treatment applied directly to the skin that creates localised heat energy in the tissue. Hyperthermia is widely acknowledged to provide a response through: Heat dissipation Tissue damage or death to cell membranes and intra-cellular structures Modulation of a number of immune processes Research using Swift in the UK focused on immune modulation, and skin keratinocytes from microwave-treated human skin were found to show induction of danger associated molecular patterns (DAMPs) such as heat shock proteins (HSP-70) that were able to signal to dendritic cells. Even at a low energy, keratinocyte induced dendritic cell activation induced enhanced cross-presentation of HPV antigens to CD8+ T cells, with consequent interferon-γ production. Interestingly, in liquid nitrogen treated control experiments, similar keratinocyte driven dendritic cell activation was not found.
17 CLINICAL STUDY THE USE OF MICROWAVES IN THE TREATMENT OF PLANTAR WARTS INDEPENDEDENT 32 PATIENT STUDY, EUROPEAN JOURNAL OF DERMATOLOGY, OCTOBER mm 15 5 AVERAGE AGE OF PATIENTS ON THE STUDY AVERAGE YEARS CONDITION HAS PERSISTED LARGEST VERRUCA TREATED IN STUDY (MEAN DIAMETER 7.34mm) QUICKEST RESOLUTION ON THE STUDY (DAYS) (AVERAGE 79 DAYS) AVERAGE TREATMENT TIME IN SECONDS 76% of patients classified as recalcitrant resolved within 4 treatments, with 94% of those resolving within 3 treatments 11/6/
18 Link to full research paper, as published by the European Journal of Dermatology
19 PMCF 6 MONTHS CLINICAL FOLLOW-UP FOLLOW-UP DATA COLLECTED BY CLINICIANS AIMED AT GATHERING PATIENT FEEDBACK & CONFIRMING TREATMENT SAFETY 95% 10/10 72% 98% 63% OF PATIENTS WOULD RECOMMEND SWIFT TO A FRIEND 70% OF PATIENTS RATED THE TREATMENT AS 10/10 OF PATIENTS FELT A REDUCTION IN PAIN AS A RESULT OF SWIFT OF PATIENTS COULD CONTINUE DAILY TASKS AS NORMAL POST-TX OF PATIENTS TREATED HAD MULTIPLE LESIONS 77% of patients surveyed had complete resolution at 6 months-post treatment confirming the validity of the initial clinical study (76% efficacy reported) 11/6/
20 POST MARKET SURVEILLANCE DATA IN-FIELD DATA COLLECTED BY SWIFT USERS IN THE UK AIMED AT GATHERING DATA ON EFFECTIVENESS AND BEST PRACTICE PROTOCOLS
21 patient cases
22 Patient Notes 60 year old female. Lesions present for 10+ years. Clearance after 2 Swift treatments, 4 weeks apart. UK Patient, Surrey
23 Patient Notes 17 year old female with autoimmune liver disease. Lesions present for 4 years. Previous treatments included cryotherapy, laser, dry needling, various acid applications. Clearance after 3 treatments, 2 weeks apart. UK Patient, Cheshire
24 Patient Notes 17 year old male with recalcitrant VPs/warts across hands and feet (148 in total, lesions first appeared at age of 4). Previous treatments included cryotherapy, dry needling, thuja, various acid applications. Clearance after 5 treatments, 4 weeks apart. UK Patient, Portsmouth
25 Patient Notes 18 year old female Lesions present for 12 years. Previous treatments included cryotherapy and various acid applications. Clearance after 3 treatments, 4 weeks apart. UK Patient, Portsmouth
26 Questions Thank You! Marcus Baiano National Sales Manager AMT Surgical
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