Patricia L. Whitten, Ph.D.

Transcription

1 Curriculum vitae Patricia L. Whitten, Ph.D. Personal Data Current Appointment: Professor of Anthropology, Emory University Affiliations Core Faculty, Neuroscience and Behavioral Biology Program Affiliated Research Scientist, Yerkes Regional Primate Research Center Core Faculty, Center for Behavioral Neuroscience Office: Department of Anthropology Lab: Laboratory of Reproductive Ecology Geology Building, Rm 211 and Environmental Toxicology Emory University Anthropology Building, Rm 306 Atlanta, GA Emory University (404) Dickey Drive Atlanta, GA Lab: (404) Education Mellon Fellow in Reproductive Biology, Yale University School of Medicine, New Haven, CT NIMH Postdoctoral Fellow in Behavioral Biology, Yerkes Regional Primate Research Center, Emory University, Atlanta, Georgia Ph.D., Department of Anthropology, Harvard University, Cambridge, MA 1973 B.A. (High Honors), Department of Anthropology,University of Illinois, Urbana, Illinois. Minor: Biology Research Focus Throughout my professional career, I have been committed to bringing the laboratory methods of biological anthropology to behavioral primatology, combining evolutionary and mechanistic levels of analysis, bridging field and captive studies, and fostering interdisciplinary research. Hormonebehavior interactions in wild primates are a major focus of my research. My laboratory has been a leader in the development of noninvasive methods of hormone analysis, adapting these assays to a wide range of species an providing laboratory training to graduate students. My collaborators and I have used these methods to study the adaptive functions and mechanisms of behaviors such as competition and mate choice, dominance, infanticide, and friendships. Positions Held 2003-Present Professor, Department of Anthropology, Emory University, Atlanta, Georgia Associate Professor, Department of Anthropology, Emory University 1

2 Associated Associate Professor, Department of Biology, Emory University Research Affiliate in Obstetrics and Gynecology, Yale University School of Medicine, New Haven CT 1994-Present Affiliated Research Scientist, Yerkes Regional Primate Research Center, Atlanta, GA Associated Assistant Professor, Department of Biology, Emory University Assistant Professor, Department of Anthropology, Emory University Visiting Assistant Professor, Department of Obstetrics and Gynecology, Yale School of Medicine, New Haven,CT 1987 Lecturer, Department of Anthropology, Yale University, New Haven, CT Associate Research Scientist, Department of Obstetrics and Gynecology, Yale School of Medicine, New Haven, CT Visiting Assistant Professor, Department of Anthropology, University of Michigan, Ann Arbor, Michigan NIMH Research Fellow, Yerkes Regional Primate Research Center, Emory University Courses Taught Emory: Undergraduate ANT 200 Foundations of Behavior (was ANT 215; cross-listed as NBB 201, NBB core course) ANT 302 Primate Behavior and Ecology (formerly ANT 212) ANT 306 Primate Mating Strategies (undergraduate seminar, writing intensive) ANT 323 Sex Differences: Biological Bases (formerly ANT 214) ANT 385 Reproductive Ecology ANT 415 Research methods in Biological Anthropology Graduate ANT 505 ANT 520R ANT 520R Yale: Michigan: Primate Ecology and Social Organization (graduate) Biocultural Seminar Sex and Gender (Graduate) Biocultural Seminar: Language and Communication (graduate) Primate Ecology and Social Behavior (upper level undergraduate) Social Behavior of Primates (introductory) Ecology of Reproduction (graduate) Nonhuman Primate Behavior (upper level undergraduate) Honors Students Brett Abernethy Melissa Emery Thompson Quynh-Chau Ha Laboratory Methods Training Emory Graduate Students Amy Cobden 2

3 Molly Embree, Psychology Colleen Gault, Psychology Brandie Littlefield, Anthropology Karyn Meltz, Anthropology Heather Patisaul, PBEE Ronda Stavisky, Anthropology Sally Seraphin, Anthropology Amanda Thompson, Anthropology Extra-mural Graduate Students Diane Brockman, Yale University Sonia Cavigelli, Psychology, Duke University Melissa Emery Thompson, Anthropology, Harvard University Jacinta Beehner, Anthropology, Washington University-St Louis Marc Shur, Anthropology, Rutgers University Teague O'Mara, Arizona State University Undergraduate Brian Bertram (Anthropology independent research) Brett Abernethy (Anthropology and Biology Honors Research) Joshua Franklin (Biology 498) Adam Schneider (Biology 498) Ben Benander (Biology 498) Robert Oakes (Biology 498) Kevin Meckes (Anthropology independent research) Funding: Research Grants and Funded Collaborations 5/1/09-6/1/10 American Association for Laboratory Animal Science,"The use of nesting behavior for pain scoring" Whitten: Co-PI 5/08-4/09 Emory College Instrumentation, Bridge, Instruction, and Seed (IBIS) Funding Program. Blood spot and urine spot assays Whitten: PI 5/1/09-8/31/10 Leakey Foundation, Stress, sociality, and bonobos (Pan paniscus) of Lomako Forest Amy Cobden: Co-PI 7/07-6/08 NSF, Doctoral Dissertation Improvement Grant "Consequences and Mechanisms of Female Competition in Wild Sifaka," PL Whitten PI Brandie Littlefield Co-PI. 7/06-6/07 Wenner-Gren Foundation Testing hypotheses of the dietary determinants of ovarian hormones: a comparative study of three populations, VJ Vitzthum (PI), co- PIs: T Deschner, P Whitten, Nyandorj Yandag. 8/01-7/07 NSF, Biological and Cultural Perspectives on Menopause, Koonenki, in Japan, C Worthman (PI), PL Whitten (Co-Investigator). 1/04-12/04 Institute for Comparative and International Studies Research and Program Fund, Pilot Study of Ecogeographical Diversity in South African Primates to PL Whitten Center for Behavioral Neuroscience Venture Grant Dopaminergic Development & Social Affiliation: A Comparative Study of DRD1 & DRD2 Binding in 3

4 Mother and Nursery Reared Rhesus Macaques (Macaca mulatta) Jim Winslow, Sally Seraphin, Mars Sanchez, and Pat Whitten Co-PIs. 1/02-12/02 Center for Behavioral Neuroscience Venture Grant, Microarray Analysis of Estrogen-like Compounds in the Brain, L Young, H Patisaul, and PL Whitten (Co-PI s ). 7/01-6/03 NSF, Collaborative Research on Population Differences in Vervet Monkey Life History, PL Whitten (PI). (An independent jointly submitted NSF grant funds Dr Turner of U Wisc for the genetic part of this project). 1/01 Emory University International Travel Fund, Conference Grant. 7/00-12/01 Center for Behavioral Neuroscience Venture Grant, Neural Actions of Phytoestrogen Action on Reproductive Behavior, PL Whitten and L Young, (Co-PI s ). 4/99-3/00 Emory Hughes Sciences Initiative Curriculum Development Fund, Online Laboratory for Neuroscience and Behavioral Biology /99-10/03 NSF, "Center for Behavioral Neuroscience, Tom Insel (PI), PL Whitten (Core Faculty). 7/99-12/05 NSF, Socio-Demographic Factors Mediating Seasonal Testicular Function in Propithecus verreauxi D.K. Brockman (PI), Duke University/UNC-Charlotte, PL Whitten (Faculty Associate) Margot Marsh Biodiversity Fund, "Socio-Demographic Factors Mediating Seasonal Testicular Function in Propithecus verreauxi,", D.K. Brockman (PI), Duke University PL Whitten (Faculty Associate) Chemical Manufacturer's Association, "Phytoestrogen Data for Human Risk Assessment," PL Whitten (PI) National Center for Toxicological Research, FDA, Alterations in Reproductive Tract Morphology and Biochemistry in Rats Treated Neonatally with Phytoestrogens, Co-PI, Research collaboration with Frans de Waal, Yerkes Primate Research Center, funded by Behavioral and Veterinary Approaches to Primate Breeding, F. DeWaal (PI), NCRR, NIH, Research collaboration with Patty Jo Watson, Washington University, Kris Gremillion, Ohio State, Kris Sobolik, University of Maine, Sex Determination and Dietary Analysis in Paleofecal Samples, funded by Cave Archaeological Foundation Research collaboration with Sonia Cavigelli and Michael Pereira, Duke University, Fecal testosterone and sociosexual behavior in ringtailed lemurs, funded by Duke University Emory University Research Committee, "Serum Tests of Fecal Steroid Analysis," September 1992-August National Science Foundation, "Phytochemical Endocrinology" July June Research collaboration with Diane Brockman and Alison Richard, Yale University, funded by Reproduction and Mating System of Verreauxi s Sifaks, NSF Dissertation Improvement Grant to D Brockman Small Instrumentation Grant, NIH, June 1991-May Other Academic Biomedical Research Support Grant, "HPLC based Analysis of Diet, Behavior, and Endocrine Function. 4

5 1990 Emory University Research Committee, "Fecal Steroid Analysis for Use in Field Primatology: II. Determination of the Reliability of Fecal Steroids as Measures of Reproductive Function," September 1990-August Emory University Research Committee, "Fecal Steroid Analysis for Use in Field Primatology: I. Optimization of Collection and Extraction Procedures," May- August NIH research grant 5 R01 ES04297, "Effects of Dietary Plant Estrogens on Reproduction NIH research grant 1 R01 ES04297, "Effects of Dietary Plant Estrogens on Reproduction Sigma Xi Research Grant Research Grant, Wenner-Gren Foundation for Anthropological Research. Awards, Honors, and Appointments Research Affiliate, Dept OBGYN, Yale University School of Medicine 1994 Albert Levy Faculty Research Award 1985 Elected New York Academy of Sciences Mellon Foundation Fellow, Yale University School of Medicine NIMH Postdoctoral Fellowship, Emory University NIH Training Grant, Harvard University Grant-in-Aid, Harvard University 1973 Bronze Scholar, University of Illinois 1971 Elected Phi Beta Kappa, University of Illinois Illinois State Scholarship James Scholar, University of Illinois Research Experience Emory University: Effect of infants on hormonal profiles of sifaka males, collaboration with Diane Brockman 2002-Present Variation in leptin across vervet monkey populations in South Africa, collaboration with T Turner, U of Wisconsin-Milwaukee Neural actions of phytoestrogens: role of ERα and ERβ, collaboration with 1998-Present 1997-Present 1995-Present 1991-Present Larry Young, Emory Dept of Psychiatry and Heather Patisaul, CBN Hormonal consequences of male migration and social instability in sifaka, Beza Mahafaly, Madagascar Ecogeographic variation in androgen secretion, stress, and sexual maturation in vervet monkeys Noninvasive measures of stress in chimpanzees, stress and dominance rank in longtailed macaques, relation of sexual swellings to the timing of ovulation in sooty mangbeys; endocrinology of sociosexual behavior in sifaka Field endocrinology; Socioendocrinology of mate choice, competition, and reproduction; HPLC-based analysis of steroidal and plant estrogens; 5

6 development and validation of noninvasive methods of hormone analysis; experimental studies of endocrine disruptors "Effects of Dietary Plant Estrogens on Reproduction", NIEHS grant 5R01 ES04297; analysis of ovarian steroid profiles of captive and free-ranging sifaka; analysis of ovarian steroid profiles of free-ranging baboons; measurement of androgens and adrenal steroids in primate feces Establish Laboratory of Reproductive Ecology and Environmental Toxicology; PI, NIH grant, "Effects of Dietary Plant Estrogens on Reproduction"; development of methods of fecal steroid analysis for field primatology Yale University School of Medicine Experimental studies of estrogenic effects of phytoestrogen diets; PI, 1988 "Effects of Dietary Plant Estrogens on Reproduction;" extraction of plant material for phenolic analysis; purification and identification of plant phenolics; development of microassay for measuring plant phenolics; bioassays of estrogenic activity in rats; measurement of estrogen metabolism in placental microsomes; competition studies of steroid receptor affinity; isolation and measurement of occupied nuclear estrogen receptors; radioimmunoassay of steroids; extraction and analysis of fecal steroids Yerkes Regional Primate Research Center, Emory University Behavioral observations of nonhuman primates (stumptail macaques); morphometric measures of primate infants for study of growth rates; use of computerized data recording systems; design of software for data verification and analysis using FORTRAN Harvard University Design of data analysis software using SAS; database management Ecological Research in Africa: behavioral observations of wild primates (vervet monkeys); censuses of primate population size and size and distribution; ecological monitoring: assessments of vegetation density; species frequency and distribution, and phenology 1975 Stanford University Outdoor Primate Facility, Palo Alto,CA Behavioral observations of captive primates (chimpanzees); behavioral sampling techniques l972 University of Illinois Behavioral testing and artificial selection in Drosophila melanogaster Major On-Going Research Projects 1. Relation of testosterone to migration, social rank, and group stability in Madagascan sifaka (laboratory and field research with Diane Brockman, UNC-Charlotte) 2. Population and life history variation of gonadal, adrenal, and peptide hormones in vervet monkeys (research and book project with Trudy Turner, UWM) 3. Nesting behaviors as indices of pain in mice (laboratory research collaboration with Douglas Taylor (PI), Division of Animal Resources) 6

7 Professional Activities Associations: American Association of Physical Anthropologists American Anthropological Association Panels and Workshops Related to Environmental Estrogens: 2003 Role of Environmental Factors on the Onset and Progression of Puberty Expert Panel Workshop, Serono Symposium, Rosemont, Illinois, November 6-8, Endocrine Disrupter Exposure During Development: Effects on Brain and Behavior, Neurobehavioral Teratology Society, Montreal, Canada, July Endocrine Disruptors Low-Dose Peer Review Panel, National Institute of Environmental Health Sciences Workshop on Phytoestrogens in Soy Products, National Institute of Child Health and Development, NIH, Bethesda, MD, May Invited Participant, Endocrine Disruptor Research Needs Workshop, Environmental Protection Agency, Research Triangle Park, NC, April Gordon Research Conference on Hormonal Carcinogenesis, Colby-Sawyer College, New London, New Hampshire, August Third International Conference on Phytoestrogens, National Center for Toxicological Research, Food and Drug Administration, Little Rock, Arkansas, December First International Symposium on The Role of Soy in Preventing and Treating Chronic Disease, Mesa, Arizona, February Second International Conference on Phytoestrogens, National Center for Toxicological Research, FDA, Little Rock, Arkansas, October Workshop on Chemically Induced Alterations in Sexual Development: The Wildlife- Human Connection, Wingspread, Racine, Wisconsin, July Phytoestrogen Workshop, National Center for Toxicological Research, Jefferson, Arkansas. November Peer ReviewPanels: 2001 NSF panel on Biological Collections: Fall Special Review Committee on Center for Study of Dietary Supplements, National Institutes of Health 7

8 1999 Panel member, Special Review Committee on Center for Study of Dietary Supplements, National Institutes of Health Member of Physical Anthropology Grant Review Panel, National Science Foundation Member of Physical Anthropology Grant Review Panel, National Science Foundation Member of Physical Anthropology Grant Review Panel, National Science Foundation 1993 External grant reviewer, International Cooperative Biodiversity Program, NSF/USAID/NIH/NIMH 1993 Panel member, Special Review Committee on Nutrition and Cancer, National Cancer Institute, National Institutes of Health 1992 Invited reviewer, National Institutes of Health Site visit Team, Clinical Research Center, Children s Hospital, CInncinnati Ohio. Grant Reviews: National Geographic Society National Science Foundation LSB Leaky Foundation Manuscript Reviews for Journals: American Journal of Human Biology American Journal of Physical Anthropology American Journal of Primatology Behavioral Ecology and Sociobiology General and Comparative Endocrinology Hormones and Behavior Physiology and Behavior Wildlife Biology College/University Service Chair, Governance Committee 2008/9 Governance Committee Executive Committee, Graduate School of Arts and Sciences, Fall Conflict of Interest Committee Conflict of Interest Committee Conflict of Interest Committee

9 Grievance Committee National Science Foundation Behavioral Neuroscience Center Grant Committee Grievance Committee University Research committee Natural and Mathematical Sciences Subcommittee of Educational Policy Committee Education Subcommittee for CBN National Science Foundation Center Grant University Research Committee Grievance Committee Neuroscience and Behavioral Biology Program Planning Committee University Research Committee Conduct Council Conduct Council Tatoo program, Summer 1993 Departmental Service Graduate Candidate Selection Committee Space Committee Faculty Handbook Committee Space Committee Director of Graduate Studies 2004/5 Chair, Biological Anthropologist Search (C Hadley hired 2005) Director of Graduate Studies Director of Graduate Studies Chair, Curriculum Committee Director of Graduate Studies Chair, Curriculum Committee Director of Graduate Studies: Fall 2000-present Chair, Social Cognition Search Committee (J. Rilling hired 2002) Chair, Curriculum Committee Director of Graduate Studies Chair, Curriculum Committee: Fall 2000-Spring 2001 Handbook Committee Graduate Concerns Committee 9

10 Graduate Admissions Committee Undergraduate Concerns Committee Computer committee Graduate Concerns Committee Undergraduate concerns committee Biological Anthropologist Search Committee Chair, Graduate Admissions Committee Graduate Concerns Committee Graduate Admissions Committee Chair, Speakers and Colloquia Committee Anthropology Executive Committee 1993 Graduate Concerns Committee Search committee, Biocultural position Hughes Grant committee Behavioral Biology and Neurosciences Program Planning Committee Publications: Refereed Journals Whitten PL, Turner TR 2009 Endocrine mechanisms of primate life history trade-offs: Growth and reproductive maturation in vervet monkeys. American Journal of Human Biology Published online in Early View, April 28, Brockman DK, Cobden A, Whitten PL 2009 Birth season glucocorticoids are related to the presence of infants in sifaka (Propithecus verreauxi). Proceedings of the Royal Society B-Bioogical Sciences 276: Published online before print Feb Whitten PL, Turner TR 2008 Ecological and reproductive variance in serum leptin in wild vervet monkeys. American Journal of Physical Anthropology 137: Publ online Nov Wittig RM, Crockford C, Lehmann J, Whitten PL, Seyfarth RM, Cheney DL 2008 Focused grooming networks and stress alleviation in wild female baboons. Hormones and Behavior 54(1): Crockford C, Wittig RA, Whitten PL, Seyfarth RM, Cheney DL 2008 Social stressors & coping mechanisms in wild female baboons (Papio hamadryas ursinus). Hormones and Behavior 53: Seraphin SB, Whitten PL, Reynolds V 2008 The influence of age on fecal steroid hormone levels in male Budongo Forest chimpanzees (Pan troglodytes schweinfurthii). American Journal of Primatology 70:

11 Engh AL, Beehner JC, Bergman TJ, Whitten PL, Hoffmeier RR, Seyfarth RM, Cheney DL 2006 Female hierarchy instability, male immigration, and infanticide increase glucocorticoid levels in female chacma baboons. Animal Behaviour 71(5): Engh AL, Beehner JC, Bergman TJ, Whitten PL, Hoffmeier RR, Seyfarth RM, Cheney DL 2006 Behavioural and hormonal responses to predation in female chacma baboons (Papio hamadryas ursinus). Proceedings of the Royal Society B- Biological Sciences 273 (1587): Bergman TJ, Beehner JC, Cheney DL, Seyfarth RM, Whitten PL 2006 Testosterone predicts future dominance rank and mating activity among male chacma baboons. Behavioral Ecology and Sociobiology 59(4): Bergman TJ, Beehner JC, Cheney DL, Seyfarth RM, Whitten PL 2006 Interactions in male baboons: the importance of both males testosterone. Behavioral Ecology and Sociobiology 59(4): Beehner JC, Phillips-Conroy JE, Whitten PL 2005 Female testosterone, dominance rank, and aggression in an Ethiopian population of hybrid baboons. American Journal of Primatology 67: Bergman TJ, Beehner JC, Cheney DL, Seyfarth RM, Whitten PL 2005 Correlates of stress in freeranging male chacma baboons, Papio hamadryas ursinus. Animal Behaviour 70 (3): Beehner JC, Bergman TJ, Cheney DL, Seyfarth RM, Whitten PL 2005 The effects of new alpha males on female stress in free-ranging baboons. Animal Behaviour 69: Melby MK, Watanabe S, Whitten PL, Worthman CM 2005 Sensitive high-performance liquid chromatographic method using coulometric electrode array detection for the measurement of phytoestrogens in dried blood spots. Journal of Chromatography B 826: Muehlenbein MP, Watts DP, Whitten PL 2004 Dominance rank and fecal testosterone levels in adult male chimpanzees (Pan troglodytes schweinfurthii) at Ngogo, Kibale National Park, Uganda. American Journal of Primatology 64: Beehner JC, Whitten PL 2004 Modifications on a field method for fecal steroid analysis in baboons. Physiology and Behavior. Physiology & Behavior 82: Whitten PL, Turner TR 2004 Male residence and the patterning of serum testosterone in vervet monkeys (Cercopithecus aethiops). Behavioral Ecology and Sociobiology.56: Emery MA, Whitten PL 2003 Size of sexual swellings reflects ovarian function in chimpanzees (Pan troglodytes). Behavioral Ecology and Sociobiology 54: Patisaul HB, Whitten PL, Melby M, Young LJ 2002 Genistein affects ERβ but not ERα-dependent gene expression in the hypothalamus. Endocrinology 143: Whitten PL, Patisaul HB, Young LJ 2002 Neurobehavioral actions of coumestrol and related isoflavonoids in rodents. Neurotoxicology and Teratology 24:

12 Stavisky RC, Whitten PL, Hammett DH, Kaplan JR 2001 Lake pigments facilitate analysis of fecal cortisol and behavior in group-housed macaques. American Journal of Physical Anthropology 116: Patisaul HB, Dindo M, Whitten PL, Young LJ 2001 Soy isoflavone supplements antagonize reproductive behavior and ERα- and ERβ-dependent gene expression in the brain. Endocrinology 142(7): Whitten PL, Patisaul HB 2001 Cross-species and interassay comparisons of phytoestrogen action. Environmental Health Perspectives 109 Supplement 1:5-20. Brockman DK, Whitten PL, Richard AF, Benander B 2001 Birth season testosterone levels in male Verreauxi s sifaka, Propithecus verreauxi: insights into socio-demographic factors mediating seasonal testicular function. Behavioral Ecology and Sociobiology 49 (2/3): Whitten PL, Naftolin F 1999 Reproductive actions of phytoestrogens. Bailliere's Best Practice & Research Clinical Endocrinology & Metabolism 12: Patisaul HB, Whitten PL, and Young LJ 1999 Regulation of estrogen receptor beta mrna in the brain: opposite effects of 17β-estradiol and the phytoestrogen, coumestrol. Molecular Brain Research 67: Whitten PL, Brockman DK, and Stavisky R Recent advances in noninvasive techniques to monitor hormone-behavior interactions. Yearbook of Physical Anthropology 41:1-23. Brockman DK, Whitten PL, Richard AF, Schneider A, 1998 Reproduction in free-ranging male Propithecus verreauxi: Hormonal correlates of mating and aggression. American Journal of Physical Anthropology 105: Stavisky R, Whitten PL, Aureli F, Russell E 1998 Response of fecal cortisol to stress in captive chimpanzees (Pan troglodytes). American Journal of Primatology 44: Brockman DK, Whitten PL 1996 Reproduction in free-ranging Propithecus verreauxi: Estrus and the relationship between multiple mating partners and fertilization. American Journal of Physical Anthropology 100: Whitten PL, Russell E 1996 Information content of sexual swellings and fecal steroids in sooty mangabeys (Cercocebus torquatus atys). American Journal of Primatology 40: Sobolik KD, Gremillion KJ, Whitten PL, Watson PJ 1996 Sex determination of prehistoric human paleofeces. American Journal of Physical Anthropology 101: Brockman DK, Whitten PL, Russell E, Richard AF, Izard MK 1995 Application of fecal steroid techniques to the reproductive endocrinology of Verreauxi's sifaka, Propithecus verreauxi. American Journal of Primatology 36:

13 Stavisky RC, Russell E, Stallings J, Smith EO, Worthman C, Whitten PL 1995 Fecal steroid analysis of ovarian cycles in free-ranging baboons. American Journal of Primatology 36: Whitten PL, Lewis C, Russell E, Naftolin F 1995a Phytoestrogen influences on the development of behavior and gonadotropin function. Proc Soc Exp Biol Med. 208: Whitten PL, Lewis C, Russell E, Naftolin F 1995b Potential adverse effects of phytoestrogens. J Nutrition 125:771S-776S. Whitten PL, Russell E, Naftolin F 1994 Effects of phytoestrogen diets on estradiol action in the rat uterus. Steroids 57: Naftolin F, Whitten P, Keefe D 1994 An evolutionary perspective on the climacteric and menopause. Menopause 4: Whitten PL, Lewis C, Naftolin F 1993 A phytoestrogen diet induces the premature anovulatory syndrome in lactationally exposed female rats. Biology of Reproduction 49: Whitten PL, Naftolin F 1992 Effects of a phytoestrogen diet on estrogen-dependent reproductive processes in immature female rats. Steroids 57: Whitten PL, Russell E, Naftolin F 1992 Effects of a normal, human-concentration, phytoestrogen diet on rat uterine growth. Steroids 57: Nash LT, Whitten PL 1989 Preliminary observations on the role of Acacia gum chemistry in the diet and distribution of Galago senegalensis in Kenya. American Journal of Primatology 17: Whitten PL 1988 Effects of patch quality and feeding subgroup size on feeding success in vervet monkeys (Cercopithecus aethiops). Behaviour 105: Smith EO, Whitten PL 1988 Triadic interactions in savannah dwelling primates. International Journal of Primatology 91: Turner TR, Whitten PL, Jolly CJ, Else JG 1987 Pregnancy outcome in free-ranging vervet monkeys. American Journal of Primatology 12: Whitten PL, Smith EO 1984 Patterning of wounding in stumptail macaques (Macaca arctoides). Primates 25: Whitten, PL 1983 Diet and dominance among female vervet monkeys. American Journal of Primatology 5:

14 Publications: Book Chapters Seraphin SB, Whitten PL, Reynolds V 2006 The interaction of hormones with ecological factors in male Budongo Forest chimpanzees. In: Primates of Western Uganda, ed. by Newton-Fisher, N.E.; Notman, H.; Paterson, J.D., Reynolds, V.; Springer, New York, pp Patisaul HB, Whitten, PL 2004 Dietary phytoestrogens. In: Endocrine Disruptors: Effects on Male and Female Reproductive Systems,.Second Edition, ed. by R. K. Naz, CRC Press, Boca Raton, Florida, pp Whitten PL, Brockman DK 2001 Strepsirrhine reproductive ecology. In: Reproductive Ecology and Human Evolution, ed. by P. Ellison, Aldine, pp Whitten PL 2000 Evolutionary endocrinology of the cercopithecoids. In: Old World Monkeys, edited by PE Whitehead and CJ Jolly, Cambridge University Press, pp Whitten PL 1999 Diet, hormones, and health: An evolutionary-ecological perspective. In: Hormones, Health, and Behavior, edited by C Panterbrick and CM Worthman, Cambridge University Press, pp Patisaul HB and Whitten PL 1999 Dietary phytoestrogens. In: Endocrine Disruptors: Effects on Male and Female Reproductive Systems, ed. By R. K. Naz, CRC Press, Boca Raton, Florida, pp Whitten PL, Kudo S, Okubo KK 1997 Isoflavonoids. CRC Handbook of Plant and Fungal Toxins, ed. by J. P. by Felix D Mello. CRC Press Inc, New York, NY, pp Whitten PL, Naftolin F 1994 Xenoestrogens and neuroendocrine development. In: Prenatal Exposure to Environmental Toxicants: Developmental Consequences, edited by H. L. Needleman and D. Bellinger, Johns Hopkins University Press, pp Whitten PL Chemical revolution to sexual revolution: Historical changes in human reproductive development. In: Chemically-Induced Alterations in Sexual and Functional Development: the Wildlife/Human Connection, edited by T. Colburn and Coralie Clement, Advances in Modern Environmental Toxicology, Vol. 21, Princeton Scientific Publishers, Princeton, NJ, pp Lavy G, Whitten PL, Naftolin F 1991 Introduction to vertebrate reproductive endocrinology. In: Vertebrate Endocrinology: Fundamentals and Biomedical Implications, Volume 4, Part A: Reproduction, edited by P. K. Pang, M. P. Schreibman, and R. Jones. New York, Academic Press, pp Whitten PL, Naftolin F 1991 Dietary estrogens: A biologically active background for estrogen action. In: The New Biology of Steroid Hormones, edited by R. Hochberg and F. Naftolin, Raven Press, pp

15 Hrdy SB, Whitten PL 1987 The patterning of sexual activity. Primate Societies, Edited by B. B. Smuts, D. L. Cheney, R. M. Seyfarth, R. W. Wrangham, and T. T. Struhsaker, University of Chicago Press, Chicago, pp Whitten PL 1987 Males and infants. Primate Societies, Edited by B. B. Smuts, D. L. Cheney, R. M. Seyfarth, R. W. Wrangham, and T. T. Struhsaker, University of Chicago Press, Chicago, pp Whitten PL 1986 Pendulums and females: Review of Female Strategies. American Journal of Primatology 10: Whitten PL 1984 Competition among female vervet monkeys. Female Primates: Studies by Women Primatologists, edited by M.F. Small, Alan R. Liss, New York, New York, pp Whitten PL 1982 Female reproductive strategies among vervet monkeys. PhD thesis, Harvard University, Cambridge, MA. Publications: Abstracts Whitten PL, Turner TR Architecture of life history events in vervet monkeys (Cercopithecus aethiops) (Abstract). American Journal Of Physical Anthropology Suppl. 48:271 Published: th Annual Meeting of the American-Association-of-Physical-Anthropologists, MAR 31-APR 03, 2009 Chicago, IL Shur MD, Palombit RA, Whitten PL 2008 Protection from male versus female harassment: Friendship and association with glucocorticoid concentrations in lactating wild olive baboons (Papio hamadryas anubis) in Laikipia, Kenya (Abstract). American Journal of Primatology Suppl. 1, 70: 28. Published: JUN 2008 Cobden AK, White FJ, Waller MT, Malone NM, Whitten PL 2008 Glucocorticoids and the question of egalitarianism in bonobos (Pan paniscus). American Journal of Physical Anthropology Suppl. 46:80 Published: 2008 Shur MD, Palombit RA, Whitten PL 2008 Association between male testosterone and friendship formation with lactating females in wild olive baboons (Papio hamadryas anubis). American Journal of Physical Anthropology Suppl 46: 193. Whitten PL, Turner TR 2008 Endocrine mechanisms of primate life history tradeoffs: Growth and reproductive maturation in vervet monkeys. American Journal of Human Biology 20(2):238-9 (Abstract). Published: MAR-APR

16 Brockman DK, Cobden A, Whitten PL 2007 Birth season glucocorticoids are related to the presence of infants in male sifaka (Propithecus verreauxi). American Journal of Physical Anthropology 132 (S44) Supplement: 81 (Abstract). Danzy JL, Seelig D, Bermudez P, Koshkin V, Whitten PL, Gerald MS 2007 The color of stress? Preliminary evidence linking sexual skin coloration with cortisol in free-ranging rhesus American Journal of Physical Anthropology 132 (S44) Supplement: 95 (Abstract). Koshkin V, Bermudez P, Seelig D, Danzy JL, Whitten PL, Gerald MS 2007 The relationship of fecal glucocorticoid levels with self-grooming rates and frequencies of being displaced in female rhesus macaques (Macaca mulatta) American Journal of Physical Anthropology 132 (S44) Supplement: 147 (Abstract). Thompson AL, Whitten PL, Lampl M 2007 Feeding, hormones and body composition: a reproductive ecological approach to the study of infant growth. American Journal of Physical Anthropology 132 (S44) Supplement: 231 (Abstract) Whitten PL, Turner TR 2007 Female reproductive state, ecology, and serum leptin in wild vervet monkeys (Chlorocebus aethiops). American Journal of Physical Anthropology 132 (S44) Supplement: 248 (Abstract). Thompson AL, Lampl M, Whitten PL 2006 Measurement of testosterone from infant fecal samples. American Journal of Physical Anthropology 129 (S42) Supplement: 176 (Abstract). Seraphin, S.B., Sterk, S., Smith, L., Embree, M., Speth, R., Whitten, P.L., Sanchez, M.M., Winslow, J.T The frontal neuroanatomy, behavioral pharmacology, and neuroendocrinology of dopamine in mother-reared and nursery-reared rhesus monkeys (Macaca mulatta). Abstract presented at the 2004 meeting of the Society for Neuroscience. Thompson, AL, M Lampl, JB Millette, PL Whitten 2005 Non-invasive methods for steroid measurement during infancy. American Journal of Physical Anthropology 126 Suppl 40: 210 (Abstract). Grobler PJ, Jacquier M, de Nys H, Blair M, Whitten PL, Turner TR 2005 Primate sanctuaries, taxonomy and survival: A case study from South Africa. American Journal of Physical Anthropology 126 Suppl 40: (Abstract). Brockman BK, Whitten PL, Millette J 2005 Lemurs diverge in expression of a hormonal biomarker of life history. American Journal of Physical Anthropology 126 Suppl 40: 82 (Abstract). Whitten PL, Turner TR 2004 Serum leptin reflects ecological differences in vervet monkey (Cercopithecus aethiops) populations. American Journal of Physical Anthropology 123 Suppl 38: 208 (Abstract). Brockman DK, Whitten PL 2004 Male-infant interactions in wild sifaka (Propithecus verreauxi). American Journal of Physical Anthropology 123 Suppl 38: 68 (Abstract). 16

17 Norconk M, Whitten PL, Vacco K 2003 Correlation of fecal testosterone levels with age in whitefaced saki males (Pithecia pithecia). American Journal of Physical Anthropology 120 Suppl 36: 159 (Abstract). Brockman D, Meltz K, Whitten PL 2003 Noninvasive assessments of stress in male sifaka (Propithecus verreauxi). American Journal of Physical Anthropology 120 Suppl 36: 72 (Abstract). Whitten PL, Turner TR 2003 Endocrine components of life history trade-offs in vervet monkeys (Cercopithecus aethiops). American Journal of Physical Anthropology 120 Suppl 36: 224 (Abstract). Seraphin SB, Whitten PL, Reynolds V 2001 Reproductive challenge and competition stress in the life of male chimpanzees (Pan troglodytes schweinfurthii) free-ranging in Budongo Forest, Uganda. :American Journal of Primatology 54(S1): 70 (Abstract). Stavisky R, Brandenberger M, Hook E, Russell E, Kaplan J, Whitten P 2001 The effect of menstrual cycle phase on cortisol excretion in female cynomolgus monkeys (Macaca fascicularis). American Journal of Primatology 54(S1): (Abstract). Fontenot MB, Stavisky RC, Seraphin S, Whitten P 2001 Aging in primates: patterns of dehydroepiandrosterone sulfate excretion in chimpanzees (Pan troglodytes). American Journal of Primatology 54(S1):71 (Abstract). Aureli F, Seres M, Whitten PL, de Waal FB 2001 Living conditions affect stress levels of captive chimpanzees. American Journal of Primatology 54(S1) : (Abstract). Bergman TJ, Whitten PL 2000 Fecal cortisol and testosterone in relation to ancestry and behavior in hybrid male baboons. American Journal of Physical Anthropology 111 Suppl 30: (Abstract). Brockman DK, Whitten PL, Richard AF 2000 Birth season cortisol levels in dispersing male Propithecus verreauxi. American Journal of Physical Anthropology 111 Suppl 30: (Abstract). Whitten PL, Turner TR 2000 A endocrine biomarker of life history in male primates. American Journal of Physical Anthropology 111 Suppl 30: 320 (Abstract). Beehner JC, Phillips-Conroy JE, Bergman TJ, Jolly JC, Whitten PL 1999 A field method for the assessment of gonadal, adrenal, and ovarian function in baboons using fecal steroid analysis. American Journal of Physical Anthropology 108 Suppl 28: 89 (Abstract). Brockman DK Whitten PL 1999 Group transfer and male competition in Propithecus verreauxi: insights into factors mediating male infanticide in a seasonally breeding primate. American Journal of Physical Anthropology 108 Suppl 28: 98 (Abstract). 17

18 Whitten PL, Turner TR, Jolly C 1998 Ecogeographic variation in testosterone in vervet monkeys: a primate test of the challenge hypothesis. American Journal of Physical Anthropology 105 Suppl. 26: (Abstract). Brockman DK, Whitten PL, Beaupret H 1998 Androgen-behavior relationships in female Verreauxi s sifaka. American Journal of Physical Anthropology 105 Suppl. 26: (Abstract). Whitten PL 1995 Sexing prehistoric human remains by fecal steroid analysis. American Journal of Physical Anthropology 96 (Abstract). Cavigelli S, Pereira M, Whitten PL 1995 Fecal testosterone and sociosexual behavior in ringtailed lemurs (Lemur catta). Annual Meeting of the Animal Behaviour Society (Abstract). Stavisky RC, Wilson M, Russell E, Whitten PL 1994 Validation of the fecal extraction method: Correlation of serum and fecal endocrine profiles in rhesus macaques. American Journal of Physical Anthropology Supplement 18:186 (Abstract). Brockman DK, Whitten PL, Russell E, Richard AR, Izard MK 1994 Hormonal correlates of reproduction and mating in free-ranging female Propithecus verreauxi in Beza Mahafaly, Madagascar. American Journal of Primatology 33:198 (Abstract). Whitten, PL 1994 The evolutionary endocrinology of life history. American Journal of Physical Anthropology Supplement 18: 206 (Abstract). Whitten PL, Brockman D, Russell E, Richard A, Izard K Chromatographic analysis of steroid metabolites in sifaka feces. American J Physical Anthropology Supplement 16: 208 (Abstract). Stavisky RC, Russell E, Whitten PL 1993 High performance liquid chromatography of baboon fecal steroids. American J Physical Anthropology Supplement 16:187(Abstract). Brockman D, Whitten PL, Russell E, Richard A, Izard K 1993 Measuring gonadal fecal steroids in female sifaka, Propithecus verreauxi. American J Physical Anthropology Supplement 16:63 (Abstract). Whitten PL Phytochemical endocrinology: New paradigms for the evolution and ontogeny of alternative reproductive strategies. American Journal of Physical Anthropology Supplement 14: (Abstract). Stavisky R, Russell E, Whitten P Noninvasive methods for the detection of androgen and adrenal steroids in free-ranging primates. American Journal of Physical Anthropology Supplement 14: (Abstract). Stavisky R, Whitten, PL, Smith EO 1991 Fecal steroid extraction in yellow baboons Papio cynocephalus. American Journal of Physical Anthropology Supplement 12: 168 (Abstract). 18

19 Whitten PL, Naftolin F 1988 Natural components of human diets are estrogens. American Journal of Physical Anthropology 75(2):287 (Abstract). Whitten PL, Smith EO, Murray RD 1985 Orange intake associated with menstrual irregularities in stumptail macaques (Macaca arctoides). American Journal of Physical Anthropology 66:242 (Abstract). Whitten, PL, Naftolin F 1985 Hormonally active plant chemicals in vervet monkey diets. American Journal of Primatology 12: (Abstract). Whitten, PL 1984 The relation of diet to mating seasonality among wild vervet monkeys. American Journal of Physical Anthropology 63:234 (Abstract). Whitten, PL, Smith EO 1984 Female rank and food intake in captive stumptail macaques (Macaca arctoides). American Journal of Primatology 6:426 (Abstract). Smith EO, Whitten PL, Murray RD 1984 Maternal body weight and maternal investment in stumptail macaques (Macaca arctoides). American Journal of Physical Anthropology 63: (Abstract). Whitten PL 1983 Females, flowers, and fertility. American Journal of Physical Anthropology 60: (Abstract). Whitten PL 1981 Fissions and fusions in vervet monkey (Cercopithecus aethiops) troops. American Journal of Physical Anthropology 54: (Abstract). Books in Progress Turner TR, Whitten PL Primate Priorities: Vervet Monkey Life History. (Contract with Cambridge University Press). Recent Lectures, Symposia, Workshops, and Presented Papers Whitten PL, Turner TR Architecture of life history events in vervet monkeys (Cercopithecus aethiops) Invited presentation in Invited Symposium Human Life History in Primate Perspective, Organizers: Benjamin Campbell and Sylvia Atsalis, at 78th Annual Meeting of the American-Association-of-Physical-Anthropologists, MAR 31-APR 03, 2009 Chicago, IL Whitten PL, Turner TR 2008 Endocrine mechanisms of primate life history tradeoffs: Growth and reproductive maturation in vervet monkeys. Invited presentation in Plenary Session Evolutionary Endocrinology: Integrating proximate mechanisms, ontogeny, and evolved function at the 33 rd Annual Meeting of the Human Biology Association, Columbus OH, April 9-10, Whitten, PL "Progress and challenges in primate behavioral endocrinology," Invited lecture at the 30 th anniversary symposium of the German Primate Centre, August 30, 2007, Göttingen, Germany. 19

20 Whitten PL How can population genetics and endocrinology inform our understanding of primat behavior, ecology, and demography? Introduction to panel discussion for workshop on Evolutionary Anthropology at the Interface, Wenner Gren Foundation, New York (Oct 4-6, 2007). Thompson AL, Lampl M, Whitten PL Measurement of testosterone from infant fecal samples. Contributed poster to the Seventy-Fifth Annual Meeting of the American Associaton of Physical Anthropologists, Anchorage, Alaska, March 8-11, Thompson, AL, M Lampl, JB Millette, PL Whitten Non-invasive methods for steroid measurement during infancy. Contributed poster to the Seventy-Fourth Annual Meeting of the American Association of Physical Anthropologists, Milwaukee, Wisconsin, April 6-9, Grobler PJ, Jacquier M, de Nys H, Blair M, Whitten PL, Turner TR Primate sanctuaries, taxonomy and survival: A case study from South Africa. Invited paper to Wiley Liss Symposium, The Human-Nonhuman Primate Interface: History, Evolution, and Conservation, organized by Trudy Turner, Augustin Fuentes, and Fred Anapol, at the Seventy-Fourth Annual Meeting of the American Association of Physical Anthropologists, Milwaukee, Wisconsin, April 6-9, Brockman BK, Whitten PL, Millette J Lemurs diverge in expression of a hormonal biomarker of life history. Contributed poster to the Seventy-Fourth Annual Meeting of the American Association of Physical Anthropologists, Milwaukee, Wisconsin, April 6-9, Male-infant interactions in wild sifaka (Propithecus verreauxi). Brockman DK, Whitten PL 2004 Contributed poster to the Annual Meeting of the American Association of Physical Anthropologists Tampa, Florida, April 14-17, Serum leptin reflects ecological differences in vervet monkey (Cercopithecus aethiops) populations. Whitten PL, Turner TR Contributed poster to the Annual Meeting of the American Association of Physical Anthropologists, Tampa, Florida, April 14-17, Noninvasive assessments of stress in male sifaka (Propithecus verreauxi). Brockman D, Meltz K, Whitten PL Contributed poster to SevenAnnual Meeting of the American Association of Physical Anthropologists April 26, Endocrine components of life history trade-offs in vervet monkeys (Cercopithecus aethiops) Whitten PL, Turner TR Annual Meeting of the American Association of Physical Anthropologists April 26, Correlation of fecal testosterone levels with age in white-faced saki males (Pithecia pithecia). Norconk M, Whitten PL, Vacco K Annual Meeting of the American Association of Physical Anthropologists April 25, An ecological approach to vervet monkey life history, TR Turner, PL Whitten, JP Gray, paper presented at the 18 th Congress of the International Primatological Society, Primates in the New Millenium, Adelaide, South Australia, January 7-12,

21 Neurobehavioral actions of coumestrol and related isoflavonoids, paper presented at the 2001 meeting of the Neurobehavioral Teratology Society, Endocrine Disrupter Exposure During Development: Effects on Brain and Behavior, Montreal, Canada, July 26, Hormonal Profiles of Life History in Vervet Monkeys, Duke University Department of Biological Anthropology and Anatomy, March 22, An endocrine biomarker of life history in male primates. PL Whitten & TR Turner. Presented at the 69 th Annual Meeting of the American Association of Physical Anthropologists, April 10-15, 2000, San Antonio TX. Fecal cortisol and testosterone in relation to ancestry and behavior in hybrid male baboons. TJ Bergman & PL Whitten Presented at the 69 th Annual Meeting of the American Association of Physical Anthropologists, April 10-15, 2000, San Antonio TX. Birth season cortisol levels in dispersing male Propithecus verreauxi. Brockman DK, Whitten PL, Richard AF Presented at the 69 th Annual Meeting of the American Association of Physical Anthropologists, April 10-15, 2000, San Antonio TX. Hormonal correlates of male migration and aggression in a female-dominant lemur. Presented to Harvard University Bioanthropology Wing, October 28, Social and ecological variation in male testosterone levels PL Whitten. Presented at: Male Gender and Health: Anthropological Perspectives, March 20-21, 1998, Emory University. Ecogeographic variation in testosterone in vervet monkeys: a primate test of the challenge hypothesis PL Whitten, TR Turner, and C Jolly. Presented at the Sixty-seventh Annual Meeting of the American Association of Physical Anthropologists, April 1-4, 1998, Salt Lake City, Utah. Androgen-behavior relationships in female Verreauxi s sifaka. Brockman DK, Whitten PL, Beaupret H 1998 Presented at the Sixty-seventh Annual Meeting of the American Association of Physical Anthropologists, April 1-4, 1998, Salt Lake City, Utah. "Two gonads in search of a neuron: Male strategies in a "primitive" primate." Presented in the Anthropology Department Faculty Colloquia Series, September 18, Noninvasive methods for the study of stress, reproductive function, and aggression. Sixty-sixth Annual Meeting of the American Association of Physical Anthropologists, St. Louis, Missouri, April 2-5, Reproduction in free-ranging male Propithecus verreauxi: Hormonal correlates of mating and aggression. D. Brockman and P. L. Whitten Sixty-sixth Annual Meeting of the American Association of Physical Anthropologists, St. Louis, Missouri, April 2-5, Use of Lake pigments to examine the relationship between dominance and fecal cortisol levels in group-housed Macaca fascicularis. R.C. Stavisky, P.L. Whitten, D. H. Hammett, J. Kaplan 21

22 Sixty-sixth Annual Meeting of the American Association of Physical Anthropologists, St. Louis, Missouri, April 2-5, Relative potency of phytoestrogens as developmental toxicants, Meeting on Phytoestrogens in Soy Products, National Institute of Child Health and Development, NIH, Bethesda, MD, May 15, Estrogenic Potency of Phytoestrogens, Department of Pharmacology and Toxicology, University of Texas Medical Branch at Galveston, May 21, Signal value of sexual swellings and fecal steroids in sooty mangabeys (Cercocebus torquatus atys). Sixty-Fifth Annual Meeting of the American Association of Physical Anthropologists, Research Triangle Park, North Carolina, April 9-13, Fecal cortisol levels and acute stress in captive chimpanzees (Pan troglodytes). R Stavisky, F Aureli, PL Whitten Sixty-Fifth Annual Meeting of the American Association of Physical Anthropologists, Research Triange Park, North Carolina, April 9-13, Hormonal correlates of reproduction in free-ranging male Propithecus verreauxi at Beza Mahafaly, Madagascar. D. Brockman and P. Whitten Sixty-Fifth Annual Meeting of the American Association of Physical Anthropologists, Research Triange Park, North Carolina, April 9-13, Nutrition, stress, and reproduction. Conservation Workshop, Brookfield Zoological Society, Chicago, IL, August 9-10, Cross-species and behavioral applicability of fecal steroid techniques. Meeting of the International Primatological Society. Madison, Wisconsin, August 11-16, Dietary Phytoestrogens, Gordon Research Conference on Hormonal Carcinogenesis, Colby- Sawyer College, New London, New Hampshire, August 6-11, "Phytoestrogen Influences on Neonatal Androgen Production," Third International Conference on Phytoestrogens, National Center for Toxicological Research, FDA, Little Rock, Arkansas, December 3-6, "Potential Adverse Effects of Phytoestrogens," First International Symposium on The Role of Soy in Preventing and Treating Chronic Disease, Mesa, Arizona, February 20-23, "Phytoestrogen Influences On The Development Of Behavior and Gonadotropin Function," Second International Conference on Phytoestrogens, National Center for Toxicological Research, FDA, Little Rock, Arkansas, October 17-20, "Plant Flavonoids: Biologically Active Estrogens With Relevance for Human Health and Animal Ecology," Biology Department, Emory University, April 20, "Phytochemical Effects on Fitness," Department of Anthropology, SUNY/Buffalo, March 22,