Kantar Health NHWS Overview

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1 Kantar Health NHWS Overview For more information, please contact:

2 What is the National Health and Wellness Survey (NHWS)? High view Journey through the system Holistic view of the patient that can only be captured from the patient 10 countries including emerging markets Consistent methods/measures Country-specific nuances Low view Attitudes, behaviours, characteristics and demographics The largest global selfreported general population survey Lifestyles and demographics Symptoms Self-rated severity Co-morbidities and risk factors Treatments adherence and satisfaction Quality of life and health utilities Work productivity Resource utilization Validated instruments Non-exclusive coverage (adults 18+) National projected values Latent populations including symptomatic undiagnosed and untreated

3 How NHWS is specific All patients, including undiagnosed symptomatic, but unaware (validated scales), untreated, OTC only, uninsured 165 conditions + risk factors including those not usually screened by physicians or reported by patients (e.g. alcohol consumption, ED, pain, ) Comprehensive patient-centric information, which provides a comprehensive overview of co-morbidities and granular segments Reliable unmet needs evaluation (e.g. burden of illness, adherence ) as information is provided directly from the patient with no physician bias International across 10 key geographies, consistent and comparable data across geographies Representative of the population = projectable Results immediately available

4 Representative of the population providing comparable results across countries APPROXIMATELY 260,000+ PARTICIPANTS ACROSS THE TEN COUNTRIES US 5EU Russia Japan Brazil A mixed method: online internet-based in the US and Japan and off-line recruitment in most other geographies to capture elderly population Representative of the adult population in each country; recent census info informs sample plan In Russia and China, representative of the urban population China target sample size

5 A wide range of metrics captured to help address your specific objectives Market Epidemiology Prevalence & Incidence Class of Treatment Trends Attitudes Behaviours Characteristics Demographics General Healthcare* Preferences* Physicians Compliance Brand level usage* OTC usage Office, Hosp. and ER visits Cost cutting strategies Source of Information Physician behavior Number of days used* Satisfaction* Co-morbidities Symptoms, Frequency & severity* Quality of life & WPAI Length of time diagnosed* Family history Prescription coverage & insurance Lifestyle considerations Basics: age, gender, income, educ. Body Mass Index *Indicates where data are captured in modules and not available to all respondents within a dataset

6 Broad Therapeutic Coverage 2016 Conditions HEART OR BLOOD Angina Arrhythmia Atherosclerosis Atrial fibrillation Deep Vein Thrombosis (DVT) Heart attack Heart murmur Hemophilia A or Hemophilia B High blood pressure (Hypertension) &/or Congestive Heart Failure High cholesterol Left ventricular hypertrophy (LVH) Baby aspirin / Low dose aspirin users Mini-Stroke/Transient Ischemia Attack (TIA) Peripheral arterial disease (PAD) Peripheral vascular disease (PVD) Pulmonary Embolism Stroke Type 1 Diabetes or Type 2 Diabetes Unstable Angina/Chest pains RESPIRATORY Chronic obstructive pulmonary disease (COPD), Chronic bronchitis, Emphysema Cystic Fibrosis Tuberculosis Allergies (Nasal) Asthma INFLAMMATION/IMMUNOLOGY/CHRONIC PAIN Ankylosing Spondylitis Osteoarthritis Psoriatic Arthritis Rheumatoid Arthritis Gout Lupus Osteopenia Osteoporosis Migraine PAIN Arthritis, Back, Lower Back, Lumbar Radiculopathy, Joint pain Bladder, Pelvic / Hip, Broken Bones, Joint, Neck Carpal Tunnel Syndrome, Cancer, Phantom Limb Pain Dental Problems, Menstrual Cycle Neuropathic, Post-herpetic Neuralgia, Diabetic Neuropathic Pain, Pinched nerve, Fibromyalgia Plantar Fasciitis, Headache, Migraine Ruptured/Herniated Disc, Sciatica Shoulder Pain/Shoulder Stiffness Sprains or Strains, Tendonitis Surgery or Medical Procedure, Spinal Disk EMOTIONAL OR MENTAL Bipolar disorder Schizophrenia Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity Disorder (ADHD) Depression Anxiety Generalized anxiety disorder (GAD) Obsessive Compulsive Disorder (OCD) Panic disorder Phobias Post-Traumatic Stress Disorder (PTSD) Social anxiety disorder SLEEP CONDITIONS Insomnia, Parasomnia, Narcolepsy, Circadian rhythm sleep disorder, Sleep Apnea/Sleep disorder breathing, Sleep difficulties (other than Insomnia, Narcolepsy or Sleep Apnea) LIVER Chronic liver disease Cirrhosis Non-Alcoholic Steatohepatitis (NASH) VACCINES Hepatitis A vaccine Hepatitis B vaccine Hepatitis A / Hepatitis B combination vaccine Human papilloma virus (HPV) vaccine f Measles, mumps, rubella (MMR) vaccine Meningococcal (meningitis vaccine) Pneumococcal (pneumonia vaccine) Seasonal Influenza (flu) vaccine Tetanus, diphtheria vaccine Varicella (chicken pox vaccine) Diphtheria, Dothienenteria Haemophilus Influenza, H Influenzae Tipo B Hexavalente, Hydrophobia Japanese Encephalitis Parotiditis, Pentavalent Pertussis Combination Poliomyelitis, Prostate Cancer Rotavírus Pentavalent Rubella, Shingles, Tick-borne Encephalitis, Tuberculosis, Yellow Fever Antibiotics, Growth Hormone CAREGIVERS Alzheimer's disease, Bipolar disorder Cancer Chronic Kidney disease on dialysis COPD, Heart Disease (such as Congestive Heart Failure), Dementia, Depression Diabetes (Type I), Epilepsy, ITP (platelet disorder), Macular Degeneration, Multiple Sclerosis, Muscular Dystrophy, Osteoarthritis Parkinson's Disease, Schizophrenia, Stroke DIGESTIVE C. difficile (antibiotic-associated colitis) Crohn s Disease Ulcerative Colitis Ulcers (active/peptic stomach or duodenal) Chronic constipation Diarrhea (frequent) Diverticulitis GERD or acid reflux Heartburn Irritable bowel syndrome (IBS) SKIN OR NAIL Psoriasis Rosacea Shingles Skin ulcers/cellulitis Acne Chronic Hives Atopic Dermatitis, Dermatitis, Eczema Fungal infections of the skin or Athlete s foot Shingles UROLOGY OR KIDNEY CONDITIONS BPH (benign prostatic hyperplasia), Chronic kidney disease Moderate or severe renal/kidney disease Overactive Bladder Dry Wet / Stress Urinary Incontinence Erectile dysfunction Urinary tract infection Yeast infection NEUROLOGICAL Dementia Epilepsy Hemiplegia Multiple Sclerosis Muscular Dystrophy Parkinson's disease Alzheimer s Disease Restless Legs Syndrome / Willis Ekbom Disease (WED) WOMEN S HEALTH CONDITIONS Endometriosis Fibroids Pregnancy, Pre-term labor Dysmenorrhea, Heavy menstrual bleeding Hot flashes, Menopause Pre-menstrual dysphoric disorder (PMDD) Pre-menstrual syndrome (PMS) Contraceptives, Tubal Ligation Hysterectomy INFECTIOUS DISEASES AIDS Genital herpes, Genital warts Hepatitis A, Hepatitis B, Hepatitis C HIV EAR, EYE, DENTAL Cataracts Dry Eye Glaucoma Macular degeneration (wet or dry) MEN'S HEALTH CONDITIONS Low testosterone Pre-mature ejaculation CANCER Any tumor, Breast cancer Cervical, Colorectal Leukemia, Lymphoma Metastatic solid tumor, skin cancer Non-Small Cell Lung, Small Cell Lung Ovarian, Uterine, Prostate, Other OTHER CONDITIONS Alcoholism Connective tissue disease ITP (Idiopathic thrombocytopenic purpura) Paget's disease, Sjögren's Syndrome Smoke cessation Thyroid condition Weight Loss / Obesity Anemia Gingivitis CAP (community-acquired pneumonia) HAP (hospital-acquired pneumonia)

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