Fatty liver disease stages

Transcription

1 Fatty liver disease stages Damage to the liver from excessive drinking can lead to ARLD. Years of alcohol abuse cause the liver to become inflamed and swollen. Physical exam If your liver is inflamed, your doctor may be able to detect it by examining your abdomen for an enlarged liver. However, your liver can be inflamed without being enlarged. Let your doctor know if you've been experiencing fatigue or loss of appetite. Also, tell your doctor about any history of alcohol, medication, and supplement use. Blood tests Your doctor may find that liver enzymes are higher than normal during a routine blood test. This doesn't confirm a diagnosis of fatty liver, but it does relate to liver inflammation. Further analysis is necessary to find the cause of the inflammation. Imaging studies Your doctor may use an ultrasound to detect fat in your liver. Other imaging studies may also be done, such as CT or MRI scans. Another imaging test similar to ultrasound is a FibroScan. Like an ultrasound, a FibroScan utilizes sound waves to determine the density of the liver and the corresponding areas of fat and normal liver tissue. Imaging studies can detect fat in the liver, but they can't help your doctor confirm the extent of damage. Liver biopsy A liver biopsy is still considered the best way to determine the severity of liver disease. During a liver biopsy, your doctor will insert a needle into the liver and remove a piece of tissue for examination. They will give you a local anesthetic to lessen the pain. A liver biopsy is the only way to know for certain the severity of fatty liver or other liver diseases. The biopsy can also help your doctor determine the exact cause. "A healthy lifestyle is the cornerstone of treatment in patients with NAFLD, but specific dietary recommendations are lacking," Alferink said in a press release. "The results from this study demonstrate that animal protein is associated with NAFLD in overweight elderly

2 people.". taking more than the recommended doses of certain over-the-counter medications, such as acetaminophen (Tylenol) pregnancy. MORE: It's Time to Rethink High-Protein Diets for Weight Loss. Medically reviewed by Daniel Murrell, MD on December 6, 2018 Written by The Healthline Editorial Team. Medically reviewed by Daniel Murrell, MD on December 6, 2018 Written by The Healthline Editorial Team. The new study, which has not yet been published in a peer-reviewed journal, was recently presented at the International Liver Congress in Amsterdam. It analyzed the health and dietary records of more than 3,400 people living in the Netherlands, 70% of whom were classified as overweight by their body mass index (BMI). Fatty liver, or hepatic steatosis, is a term that describes the buildup of fat in the liver. It's normal to have small amounts of fat in your liver, but too much can become a health problem. The liver is the second largest organ in the body. It's responsible for a wide variety of functions, including processing everything we eat and drink, and filtering harmful substances from the blood. Too much fat in the liver can lead to long-term liver damage. View a body map of the liver and learn more about its function. CMS Id: Client Version: 1f4e9aa3b b15c9676cb24ae9ff2f46 Build Number: Protein is an important part of a healthy diet, but where it comes from matters. A new study suggests that a diet high in animal protein may increase the risk of fatty liver disease, especially for people who are elderly and overweight. Research is ongoing into medications that may help treat fatty liver. The first-line of treatment continues to be following recommendations to reduce your risk factors. These recommendations typically include: The liver produces and clears cholesterol in the body. Learn how liver damage can affect cholesterol and what treatments you can explore. It's estimated that 1 billion people worldwide, and 30% to 40% of Americans adults, have NAFLD. The disease can be treated with weight loss and lifestyle changes in its early stages, but can also lead to cirrhosis, cancer and liver failure. The Liver and

3 Cholesterol: What You Should Know. Early stage fatty liver is diagnosed when the proportion of liver cells that contain fat is more than 5 percent. This is often diagnosed by looking at small samples taken from the liver under a microscope. Ultrasounds, CT scans, and MRI scans can also help evaluate the fat content of the liver. The liver commonly repairs itself by rebuilding new liver cells when the old ones are damaged. When there's repeated damage to the liver, permanent scarring takes place. This condition is called cirrhosis. In mild forms, fatty liver can be a reversible condition that may improve with lifestyle modifications such as diet changes, weight loss, and increased physical activity. In many cases, fatty liver has no symptoms. Fatty liver is becoming a more common condition, currently affecting around 25 to 30 percent of people in Europe and the United States. Fatty liver becomes harmful when the condition progresses. Liver inflammation (steatohepatitis) can lead to liver scarring, liver cancer, and end-stage liver disease. The liver is a powerhouse organ, performing a variety of tasks that are essential to maintaining good health. Eat these 11 foods for optimal liver.. If you drink alcohol as a diabetic, here are seven facts that you need to know to ensure that you drink safely and responsibly. If you have fatty liver because of obesity or unhealthy eating habits, your doctor may also suggest that you increase physical activity and eliminate or add certain types of foods to your diet. Reducing the number of calories you eat each day can help you lose weight and heal your liver. In the early stages, you can improve and reverse fatty liver disease by reducing or eliminating fatty foods and foods high in sugar from your diet. Choose a balanced diet with healthier foods such as fresh fruits, fresh vegetables, whole grains, and healthy fats like those in nuts and avocados. Replace red meats with lean proteins such as soy, chicken, turkey, and fish. Sweetened drinks, juices, and sodas should be avoided. The authors write that their findings supports the theory that what overweight people eat may be just as important for liver health as how

4 many calories they consume. Their average age was 71, and about 35% had been diagnosed, via abdominal ultrasound, with nonalcoholic fatty liver disease (NAFLD). Having too much fat in the liver can lead to liver cancer and contribute to the development of diabetes and cardiovascular disease. Other research has suggested that Western-style diets, rich in animal protein and refined foods, may alter glucose metabolism and acid balance in the body. These factors may also affect liver health, says lead author Dr. Louise Alferink of Erasmus Medical Centre in Rotterdam, The Netherlands. Other ingredients in processed meat products, like nitrates, salt and heme iron, could also play a role. Subscribe today and save up to 84% off the cover price. Nonalcoholic steatohepatitis, a potentially serious form of the disease, is marked by liver inflammation, which may progress to scarring and irreversible damage. This damage is similar to the damage caused by heavy alcohol use. At its most severe, nonalcoholic steatohepatitis can progress to cirrhosis and liver failure. Although it's very similar to alcohol-related liver disease (ARLD), NAFLD isn't caused by drinking too much alcohol. Nonalcoholic steatohepatitis is more likely in these groups:. For personal accounts OR managers of institutional accounts. [e.g. BAD (BMI, age, T2DM), BAAT (BMI, age, ALT, TG), HAIR (hypertension, ALT, insulin resistance), BARG (BMI, age, AST/ALT ratio, HbA 1c or glucose), NAFLD Fibrosis Score, BARD (BMI, AST/ALT ratio, T2DM), Clinical Scoring System for Predicting NASH]. Studies describing the use of some of these were published outwith the time period covered by Poynard et al. Many people do not have symptoms, although it's common to feel tired and some people have a persistent pain in the upper right part of their abdomen (where their liver is). NAFLD isn't caused by alcohol, but drinking may make it worse. It's therefore advisable to cut down or stop drinking alcohol. High blood sugar (hyperglycemia), indicating prediabetes or actual type 2 diabetes. People with body fat concentrated in the abdomen. eat a healthy diet try to have a balanced diet high

5 in fruits, vegetables, protein and carbohydrates, but low in fat, sugar and salt; eating smaller portions of food can help, too. jaundice of the skin and eyes confusion abnormal bleeding. If you have any of the types of fatty liver disease, there are some lifestyle changes that can help:. Alcoholic fatty liver disease, also called alcoholic steatohepatitis. Risk factors A wide range of diseases and conditions can increase your risk of nonalcoholic fatty liver disease, including:. Fatty liver becomes harmful when the condition progresses. Liver inflammation (steatohepatitis) can lead to liver scarring, liver cancer, and end-stage liver disease. There are no medicines that have been approved to treat NAFLD. Studies are investigating whether a certain diabetes medicine or Vitamin E can help, but more studies are needed. Only a few people with simple fatty liver go on to develop stage 2 of the condition, called non-alcoholic steatohepatitis (NASH). 1 Department of Medical Gastroenterology, Hvidovre Hospital, University of Copenhagen, Denmark. If you already have diabetes, NAFLD increases your chance of developing heart problems. Nonalcoholic fatty liver disease occurs in every age group but especially in people in their 40s and 50s who are at high risk of heart disease because of such risk factors as obesity and type 2 diabetes. The condition is also closely linked to metabolic syndrome, which is a cluster of abnormalities including increased abdominal fat, poor ability to use the hormone insulin, high blood pressure and high blood levels of triglycerides, a type of fat. side effects of certain medications, including methotrexate (Trexall), tamoxifen (Nolvadex), amiodorone (Pacerone), and valproic acid (Depakote). Lifestyle changes can help reduce your risk for fatty liver disease and damage. Learn what 12 foods you should eat and what 6 foods to avoid. If you smoke, it's really important to give up, as this will also help to reduce your risk of heart attack and stroke. In addition to milk thistle, herbs and nutritional supplements containing alpha-lipoic acid, N- acetyl cysteine, and Omega 3 fatty acids are also cited by some physicians as being helpful to damaged liver. Various tests provide details

6 about the extent and type of liver damage you may be suffering from: 15. At this point, you will more than likely be advised by your health care provider that further testing is necessary to determine whether or not NAFLD is a factor. While a high percentage of people with simple fatty liver or NASH will not develop serious liver problems, without treatment these conditions can progress to cirrhosis, liver failure, and death. Ultrasound (ultrasonography) A noninvasive test, this technology uses sound waves to create an image of your liver. For example, when a person with one of the following conditions. 6. Magnetic resonance imaging (MRI) MRI technology produces an image of your liver via a magnetic field and radio waves. Contrast dye is sometimes used for this test. One or more abnormal cholesterol levels: high levels of triglycerides a type of blood fat or low levels of good cholesterol (known as high-density lipoprotein or HDL). Mental confusion, such as forgetfulness or trouble concentrating. Strict control of diabetes (since insulin may act as a trigger). On April 6, 2006, Medical News Today reported that of 152 patients studied with cirrhosis due to fatty liver disease (NASH), twenty-nine had died over a ten-year period. 5. Yellowing of your skin and eyes and dark, cola-colored urine. Some scientists believe that fatty liver disease may be partly genetic. NASH was originally believed to be more common in women, 8 and it is the most common cause of liver disease in adolescents. 9. Itching of your hands and feet, and eventually your entire body. Complications from untreated non-alcoholic fatty liver disease ( NAFLD ) can be grim. The seriousness of its ranking as one of the major causes of cirrhosis of the liver makes NASH a potential health problem that should not be taken lightly. If you suffer from any kind of metabolic disorder particularly diabetes or high cholesterol and you are overweight, it's doubly important to do everything you can to protect one of your most valuable assets: your liver. Eating fatty foods does not itself cause fatty liver. However, recommended treatments for NAFLD also include weight loss, exercise, and the use of

7 cholesterol-lowering medications. Bariatric surgery is indicated in some cases. Learn more about Puristat's all-natural liver cleanse programs. The exact cause of NAFLD, or fatty liver disease as it's commonly called, is unclear. Many researchers, however, believe that metabolic syndrome a cluster of disorders that increase the risk of diabetes, heart disease, and stroke 2 plays a crucial role in the development of fatty liver disease. Cirrhosis: Liver scarring results in a hard liver that is unable to function properly. Cirrhosis can be fatal. experiences a bacterial infection, hormonal abnormalities, or an accumulation of excess iron in the liver, the liver can change from simple fatty degeneration to an inflamed state. Bleeding from engorged veins in your esophagus or intestines.