CURRICULUM VITAE

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1 CURRICULUM VITAE Name Date of Birth Nationality Marital Status Permanent Address Sang Soo Lee, M. D. August 6, 1968 Korean Married, one child Hanshin APT Jamwon dong, Seocho-gu, Seoul, KOREA Office Address Department of Gastroenterology, Asan Medical Center Pungnap-2dong, Songpa-gu Seoul , Korea Telephone Fax EDUCATION Hanyang University College of Medicine, 1995 Master's degree of Medicine, 2000, Hanyang University Doctorate degree of Medicine, 2005, University of Ulsan PROFESSIONAL APPOINTMENTS Medical Internship, Asan Medical Center, Seoul, Korea, Residency in Internal Medicine, Asan Medical Center, Seoul, Korea, Clinical and Research Fellow, Department of Gastroenterology, Asan Medical Center, Seoul, Korea, Clinical Instructor, Department of Gastroenterology, Asan Medical Center, Assistant Professor, Department of Gastroenterology, Asan Medical Center, Seoul, Korea, Associate Professor, Department of Gastroenterology, Asan Medical Center, Seoul, Korea, 2010-present

2 SPECIAL CERTIFICATION The Korean Board of Internal Medicine (#6758) The Korean Board of Gastroenterology (# ) The Korean Board of Gastrointestinal Endoscopy (# ) MEMBERSHIP The Korean Association of Internal Medicine The Korean Society of Gastroenterology The Korean Society of Gastrointestinal Endoscopy The American Society for Gastrointestinal Endoscopy MAJOR PUBLICATIONS Corresponding and 1 st author Song TJ, Kim JH, Lee SS, Eum JB, Moon SH, Park do H, Seo DW, Lee SK, Jang SJ, Yun SC, Kim MH. The prospective randomized, controlled trial of endoscopic ultrasound-guided fine-needle aspiration using 22G and 19G aspiration needles for solid pancreatic or peripancreatic masses. Am J Gastroenterol Aug;105(8): Lee SS, Shin JH, Han JM, Cho CH, Kim MH, Lee SK, Kim JH, Kim KR, Shin KM, Won YH, Song HY. Histologic influence of paclitaxel-eluting covered metallic stents in a canine biliary model. Gastrointest Endosc May;69(6): Hwang CY, Lee SS, Song TJ, Moon SH, Lee D, Park do H, Seo DW, Lee SK, Kim MH. Endoscopic ultrasound guided fine needle aspiration biopsy in diagnosis of pancreatic and peripancreatic lesions: a single center experience in Korea. Gut Liver Jun;3(2): Park DH, Lee SS, Moon SH, Choi SY, Jung SW, Seo DW, Lee SK, Kim MH. Endoscopic ultrasound-guided versus conventional transmural drainage for pancreatic pseudocysts: a prospective randomized trial. Endoscopy. 2009

3 Oct;41(10): Park do H, Lee SS, Moon JH, Choi HJ, Cha SW, Kim JH, Seo DW, Lee SK, Park SH, Lee MS, Kim SJ, Kim MH. Newly designed stent for endoscopic bilateral stent-in-stent placement of metallic stents in patients with malignant hilar biliary strictures: multicenter prospective feasibility study (with videos). Gastrointest Endosc Jun;69(7): Song TJ, Lee SS, Park do H, Lee TY, Lee SO, Seo DW, Lee SK, Kim MH. Yield of EUS-guided FNA on the diagnosis of pancreatic/peripancreatic tuberculosis. Gastrointest Endosc Mar;69(3 Pt 1): Lee SS, Shin JH, Woo CW, Hwang JC, Park CS, Kim HJ, Kim EY, Kim TH, Song HY. A new model of tracheal stenosis in dogs using combined bronchoscopic electrocautery and ethanol injection. J Vasc Interv Radiol May;19(5): Lee SS, Park do H, Hwang CY, Ahn CS, Lee TY, Seo DW, Lee SK, Kim MH. EUSguided Transmural Cholecystostomy as Rescue Management for Acute Cholecystitis in Elderly or High Risk Patients: A Prospective Feasibility Study. Gastrointest Endosc 2007;66: Lee TY, Lee SS, Jung SW, Jeon SH, Yun SC, Oh HC, Kwon S, Lee SK, Seo DW, Kim MH, Suh DJ. Hepatitis B virus infection and intrahepatic cholangiocarcinoma in Korea: a case-control study. Am J Gastroenterol Jul;103(7): Lee SS, Kim MH, Lee SK, Kim TK, Seo DW, Park JS, Hwang CY, Chang HS, Min YI. MR cholangiography versus cholangioscopy for evaluation of longitudinal extension of hilar cholangiocarcinoma. Gastrointest Endosc 2002;56: Lee SS, Kim MH, Lee SK, Kim KP, Kim HJ, Bae JS, Kim HJ, Seo DW, Ha HK, Kim JS, Kim CD, Chung JP, Min YI. Ectopic opening of the common bile duct in the duodenal bulb: clinical implications. Gastrointest Endosc 2003;57: Lee SS, Kim MH, Lee SK, Jang SJ, Song MH, Kim KP, Kim HJ, Seo DW, Song DE, Yu E, Lee SG, Min YI. Clinicopathologic review of 58 patients with biliary papillomatosis. Cancer 2004;100:

4 Co-Author Moon SH, Kim MH, Park do H, Song TJ, Eum J, Lee SS, Seo DW, Lee SK. Modified fully covered self-expandable metal stents with antimigration features for benign pancreatic-duct strictures in advanced chronic pancreatitis, with a focus on the safety profile and reducing migration. Gastrointest Endosc Jul;72(1): Epub 2010 May 20. Koo JE, Park do H, Oh J, Lee YH, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. EUS-Guided Multitransgastric Endoscopic Necrosectomy for Infected Pancreatic Necrosis with Noncontagious Retroperitoneal and Peritoneal Extension. Gut Liver Mar;4(1): Epub 2010 Mar 30. PubMed PMID: Park SH, Kim MH, Kim SY, Kim HJ, Moon SH, Lee SS, Byun JH, Lee SK, Seo DW, Lee MG. Magnetic Resonance Cholangiopancreatography for the Diagnostic Evaluation of Autoimmune Pancreatitis. Pancreas May 7. [Epub ahead of print] Yang DH, Lee SK, Moon SH, Park do H, Lee SS, Seo DW, Kim MH. Percutaneous transhepatic cholangioscopic intervention in the management of complete membranous occlusion of bilioenteric anastomosis: report of two cases. Gut Liver Dec;3(4): Epub 2009 Dec 31. PubMed PMID: Park J, Kim MH, Kim KP, Park do H, Moon SH, Song TJ, Eum J, Lee SS, Seo DW, Lee SK. Natural History and Prognostic Factors of Advanced Cholangiocarcinoma without Surgery, Chemotherapy, or Radiotherapy: A Large-Scale Observational Study. Gut Liver Dec;3(4): Noh SH, Park do H, Kim YR, Chun Y, Lee HC, Lee SO, Lee SS, Seo DW, Lee SK, Kim MH. EUS-guided drainage of hepatic abscesses not accessible to percutaneous

5 drainage (with videos). Gastrointest Endosc Jun;71(7): Moon SH, Kim MH, Park do H, Song TJ, Eum J, Lee SS, Seo DW, Lee SK. IgG4 immunostaining of duodenal papillary biopsy specimens may be useful for supporting a diagnosis of autoimmune pancreatitis. Gastrointest Endosc May;71(6): Epub 2010 Mar 20. PubMed PMID: Kim JW, Moon SH, Park do H, Lee SS, Seo DW, Kim MH, Lee SK. Course of choledochal cysts according to the type of treatment. Scand J Gastroenterol Jun;45(6): Song TJ, Park do H, Eum JB, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. EUS-guided cholecystoenterostomy with single-step placement of a 7F double-pigtail plastic stent in patients who are unsuitable for cholecystectomy: a pilot study (with video). Gastrointest Endosc Mar;71(3): Park do H, Song TJ, Eum J, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. EUS-guided hepaticogastrostomy with a fully covered metal stent as the biliary diversion technique for an occluded biliary metal stent after a failed ERCP (with videos). Gastrointest Endosc Feb;71(2): Song TJ, Kim MH, Moon SH, Eum JB, Park do H, Lee SS, Seo DW, Lee SK. The combined measurement of total serum IgG and IgG4 may increase diagnostic sensitivity for autoimmune pancreatitis without sacrificing specificity, compared with IgG4 alone. Am J Gastroenterol Jul;105(7): Choi EK, Kim MH, Jang SJ, Lee KH, Hwang CY, Moon SH, Lee TY, Koh CO, Park do H, Lee SS, Seo DW, Lee SK. Differences in pancreatic immunohistochemical staining profiles of TGF-beta1, MMP-2, and TIMP-2 between autoimmune and alcoholic chronic pancreatitis. Pancreas Oct;38(7): Park do H, Koo JE, Oh J, Lee YH, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. EUS-guided biliary drainage with one-step placement of a fully covered metal

6 stent for malignant biliary obstruction: a prospective feasibility study. Am J Gastroenterol Sep;104(9): Han JH, Park do H, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. Peroral direct cholangioscopic lithotripsy with a standard upper endoscope for difficult bile duct stones (with videos). Gastrointest Endosc Jul;70(1): Epub 2009 Jan 18. PubMed PMID: Park do H, Kim MH, Moon SH, Lee SS, Seo DW, Lee SK. Feasibility and safety of placement of a newly designed, fully covered self-expandable metal stent for refractory benign pancreatic ductal strictures: a pilot study (with video). Gastrointest Endosc Dec;68(6): PubMed PMID: Oh HC, Seo DW, Kim SC, Yu E, Kim K, Moon SH, Park do H, Lee SS, Lee SK, Kim MH. Septated cystic tumors of the pancreas: is it possible to treat them by endoscopic ultrasonography-guided intervention? Scand J Gastroenterol. 2009;44(2): PubMed PMID: Jang JW, Park DH, Moon SH, Lee SS, Seo DW, Lee SK, Kim MH. Endoscopic fibrin glue injection for closure of pancreatocutaneous fistula following transgastric endoscopic necrosectomy. World J Gastroenterol Oct 21;14(39): Oh HC, Kim MH, Choi KS, Moon SH, Park do H, Lee SS, Seo DW, Lee SK, Yoo HW, Kim GH. Analysis of PRSS1 and SPINK1 mutations in Korean patients with idiopathic and familial pancreatitis. Pancreas Mar;38(2): Moon SH, Kim MH, Park DH, Hwang CY, Park SJ, Lee SS, Seo DW, Lee SK. Is a 2-week steroid trial after initial negative investigation for malignancy useful in differentiating autoimmune pancreatitis from pancreatic cancer? A prospective outcome study. Gut Dec;57(12):

7 Kim SC, Park KT, Hwang JW, Shin HC, Lee SS, Seo DW, Lee SK, Kim MH, Han DJ. Comparative analysis of clinical outcomes for laparoscopic distal pancreatic resection and open distal pancreatic resection at a single institution. Surg Endosc Oct;22(10): Kim SC, Park KT, Lee YJ, Lee SS, Seo DW, Lee SK, Kim MH, Jang SJ, Byun JH, Han DJ. Intraductal papillary mucinous neoplasm of the pancreas: clinical characteristics and treatment outcomes of 118 consecutive patients from a single center. J Hepatobiliary Pancreat Surg. 2008;15(2): Oh HC, Seo DW, Lee TY, Kim JY, Lee SS, Lee SK, Kim MH. New treatment for cystic tumors of the pancreas: EUS-guided ethanol lavage with paclitaxel injection. Gastrointest Endosc Apr;67(4): Epub 2008 Feb 11. PubMed PMID: Bang SJ, Kim MH, Kim do H, Lee TY, Kwon S, Oh HC, Kim JY, Hwang CY, Lee SS, Seo DW, Lee SK, Song DE, Jang SJ. Is pancreatic core biopsy sufficient to diagnose autoimmune chronic pancreatitis? Pancreas Jan;36(1):84-9. Kim JY, Kim MH, Lee TY, Hwang CY, Kim JS, Yun SC, Lee SS, Seo DW, Lee SK. Clinical role of 18F-FDG PET-CT in suspected and potentially operable cholangiocarcinoma: a prospective study compared with conventional imaging. Am J Gastroenterol May;103(5): Park do H, Kim MH, Oh HB, Kwon OJ, Choi YJ, Lee SS, Lee TY, Seo DW, Lee SK. Substitution of aspartic acid at position 57 of the DQbeta1 affects relapse of autoimmune pancreatitis. Gastroenterology Feb;134(2): Oh HC, Kim MH, Hwang CY, Lee TY, Lee SS, Seo DW, Lee SK. Cystic lesions of the pancreas: challenging issues in clinical practice. Am J Gastroenterol Jan;103(1):229-39; quiz 228, 240.

8 Park do H, Kim MH, Kim TN, Son HY, Lee TY, Kwon S, Oh HC, Lee SS, Seo DW, Lee SK. Endoscopic treatment for suprapancreatic biliary stricture following blunt abdominal trauma. Am J Gastroenterol 2007;102: Shin HP, Kim MH, Jung SW, Kim JC, Choi EK, Han J, Lee SS, Seo DW, Lee SK. Endoscopic removal of biliary self-expandable metallic stents: a prospective study. Endoscopy 2006;38: Cha JM, Kim MH, Lee SK, Seo DW, Lee SS, Lee JH, Lee SG, Jang SJ. Clinicopathological review of 61 patients with early bile duct cancer. Clin Oncol (R Coll Radiol) 2006;18: Chung JW, Kim MH, Choi EK, Lee SS, Seo DW, Lee SK. Mucin-hypersecreting papillomatosis of the gallbladder. Gastrointest Endosc 2006;64:435-6; discussion 436. Choi EK, Kim MH, Kim JC, Han J, Seo DW, Lee SS, Lee SK. The Japanese diagnostic criteria for autoimmune chronic pancreatitis: is it completely satisfactory? Pancreas 2006;33:13-9. Park do H, Kim MH, Choi JS, Lee SS, Seo DW, Kim JH, Han J, Kim JC, Choi EK, Lee SK. Covered versus uncovered wallstent for malignant extrahepatic biliary obstruction: a cohort comparative analysis. Clin Gastroenterol Hepatol 2006;4: Kim KP, Kim MH, Kim JC, Lee SS, Seo DW, Lee SK. Diagnostic criteria for autoimmune chronic pancreatitis revisited. World J Gastroenterol 2006;12: Kim MH, Lee SS, Lee SK, Lee SG, Suh CW, Gong GY, Park JS, Kim YH, Kim SH. Interleukin-2 gene-encoded stromal cells inhibit the growth of metastatic cholangiocarcinomas. World J Gastroenterol 2006;12: Song MH, Kim MH, Lee SK, Seo DW, Lee SS, Han J, Kim KP, Min YI, Song DE, Yu E, Jang SJ. Regression of pancreatic fibrosis after steroid therapy in patients with autoimmune chronic pancreatitis. Pancreas 2005;30:83-6.

9 Park DH, Kim MH, Lee SS, Lee SK, Kim KP, Han JM, Kim SY, Song MH, Seo DW, Kim AY, Kim TK, Min YI. Accuracy of magnetic resonance cholangiopancreatography for locating hepatolithiasis and detecting accompanying biliary strictures. Endoscopy 2004;36: Kim KP, Kim MH, Song MH, Lee SS, Seo DW, Lee SK. Autoimmune chronic pancreatitis. Am J Gastroenterol 2004;99: Park DH, Kim MH, Lee SK, Lee SS, Choi JS, Song MH, Seo DW, Min YI. Endoscopic sphincterotomy vs. endoscopic papillary balloon dilation for choledocholithiasis in patients with liver cirrhosis and coagulopathy. Gastrointest Endosc 2004;60: Song MH, Kim MH, Lee SK, Lee SS, Han J, Seo DW, Min YI, Lee DK. Endoscopic minor papilla interventions in patients without pancreas divisum. Gastrointest Endosc 2004;59: Byeon JS, Kim MH, Lee SK, Yang DH, Bae JS, Kim HJ, Lee SS, Seo DW, Min YI. Santorinicele without pancreas divisum. Gastrointest Endosc 2003;58: Kim JH, Lee SK, Kim MH, Song MH, Park DH, Kim SY, Lee SS, Seo DW, Bae JS, Kim HJ, Han J, Sung KB, Min YI. Percutaneous transhepatic cholangioscopic treatment of patients with benign bilio-enteric anastomotic strictures. Gastrointest Endosc 2003;58: Kim MH, Lee SS. [Current status of intrahepatic stones in Korea]. Korean J Gastroenterol 2003;42: Kim HJ, Kim MH, Bae JS, Lee SS, Seo DW, Lee SK. Idiopathic acute pancreatitis. J Clin Gastroenterol 2003;37: Lim JH, Kim MH, Kim TK, Lee MG, Lee SS, Lee JW, Lee KT, Lee JK, Lim HK. Papillary neoplasms of the bile duct that mimic biliary stone disease. Radiographics 2003;23: Park JS, Kim MH, Lee SK, Seo DW, Lee SS, Han J, Min YI, Hwang S, Park KM, Lee YJ, Lee SG, Sung KB. Efficacy of endoscopic and percutaneous treatments for biliary

10 complications after cadaveric and living donor liver transplantation. Gastrointest Endosc 2003;57: Kim HJ, Lee SK, Kim MH, Son JM, Lee SS, Park JS, Seo DW, Min YI. Cystic fibrosis transmembrane conductance regulators (CFTR) in biliary epithelium of patients with hepatolithiasis. Dig Dis Sci 2002;47: Park JS, Kim MH, Lee SK, Seo DW, Lee SS, Chang HS, Han J, Kim JS, Min YI. The clinical significance of papillitis of the major duodenal papilla. Gastrointest Endosc 2002;55: Kim MH, Lee SK, Seo DW, Won SY, Lee SS, Min YI. Tumors of the major duodenal papilla. Gastrointest Endosc 2001;54: Kim MH, Lee SS, Kim CD, Lee SK, Kim HJ, Park HJ, Joo YH, Kim DI, Yoo KS, Seo DW, Min YI. Incomplete pancreas divisum: is it merely a normal anatomic variant without clinical implications? Endoscopy 2001;33: Kim DI, Kim MH, Lee SK, Seo DW, Choi WB, Lee SS, Park HJ, Joo YH, Yoo KS, Kim HJ, Min YI. Risk factors for recurrence of primary bile duct stones after endoscopic biliary sphincterotomy. Gastrointest Endosc 2001;54:42-8.

: Ajou University College of Medicine, Suwon, Korea; Ajou University College of Medicine, Graduate

: Ajou University College of Medicine, Suwon, Korea; Ajou University College of Medicine, Graduate CURRICULUM VITAE NAME Hyun Woo Lee, M.D. EDUCATION 1991.3.-2001.2 : Ajou University College of Medicine, Suwon, Korea; Doctor of Medicine 2004.3-2006.2 Ajou University College of Medicine, Graduate School,

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