Chronic Pain and Neuromusculoskeletal Condi4ons

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Chronic Pain and Neuromusculoskeletal Condi4ons James J. Lehman, DC, MBA, FACO Director Health Sciences Postgraduate Educa@on Department University of Bridgeport Learning Objec4ves Correlate anatomy and the pa@ents signs and symptoms in order to locate the neuromusculoskeletal lesion(s) and properly record the findings. Approach each pa@ent s health problem with the concern of a neuromusculoskeletal clinician. Perform orthopedic and neurological examina@ons as a skilled neuromusculoskeletal clinician while u@lizing appropriate protocols. Learning Objec4ves Chart orthopedic and neurological examina@on findings with a SOAP process in order to perform a differen@al diagnosis and create a working diagnosis. Rule- in and rule- out pathologies that might present as neuromusculoskeletal complaints with the use of physical examina@on procedures including orthopedic and neurological tes@ng in order to reduce medical errors. Learning Objec4ves Implement the scien@fic method and integrate the use of an evalua@on protocol prac@ced by contemporary chiroprac@c physician in neuromusculoskeletal medicine. Provide high quality, pa@ent- centered, neuromusculoskeletal medicine for pa@ents suffering with acute and chronic pain. Persistent Pain: A Chronic Illness Acute pain usually goes away aser an injury or illness resolves. But when pain persists for months or even years, long aser whatever started the pain has gone or because the injury con@nues, it becomes a chronic condi@on and illness in its own right. A Call to Revolu@onize Chronic Pain Care in America: An Opportunity in Health Care Reform. The Mayday Fund. November 4, 2009. Amended March 4, 2010. Persistent Pain: A Chronic Illness This chronic illness of pain, if inadequately treated, can impede the lives of individuals and families and produce a huge burden in health care over- u@liza@on, lost work produc@vity and rising costs of pain- related disability. A Call to Revolu@onize Chronic Pain Care in America: An Opportunity in Health Care Reform. The Mayday Fund. November 4, 2009. Amended March 4, 2010. 1

Persistent Pain: A Chronic Illness Prompt effec@ve treatment of acute pain is cri@cal. If pain becomes persistent, it must be effec@vely managed as a chronic illness not only to limit long- term human suffering but also to prevent lost produc@vity within our society. A Call to Revolu@onize Chronic Pain Care in America: An Opportunity in Health Care Reform. The Mayday Fund. November 4, 2009. Amended March 4, 2010. Chronic Pain is a Public Health Problem Chronic pain commonly defined as pain persis@ng longer than six months affects an es@mated 70 million Americans and is a tragically overlooked public health problem. U.S. Department of Health and Human Services. Health, United States, 2006. With chartbook on trends in the health of Americans [Internet]. Hyacsville, MD: Na@onal Center for Health Sta@s@cs [cited 2 009 Sept 4]. Available from: hcp://www.cdc.gov/nchs/data/hus/hus06.pdf. Pain that extends beyond the expected period of healing. The burden of chronic pain is greater than that of diabetes, heart disease and cancer combined. Turk, D.C.; Okifuji, A. (2001). "Pain terms and taxonomies". In Loeser, D.; Butler, S. H.; Chapman, J.J. et al. Bonica's management of pain (3 ed.). Lippincoc Williams & Wilkins. pp. 18 25. Data on specific disease burdens is available from the Center for disease Control and Preven@on s FastStats website available from: hcp://www.cdc.gov/nchs/ fastats/. The burden of pain is available from: hcp:// www.cdc.gov/nchs/data/hus/hus06.pdf Chronic Pain is a Public Health Problem Poorly assessed, unrelieved chronic pain can rob individuals and family members of a high quality of life, and it profoundly burdens society as a whole. A 1998 Na@onal Ins@tutes of Health (NIH) report concluded that just the economic toll of chronic pain may be es@mated at $100 billion a year in the United States. It has increased significantly since then Na@onal Ins@tutes of Health [Internet]. NIH guide: new direc@ons in pain research: I. Bethesda, MD: Na@onal Ins@tutes of Health. 1998 Sept 4 [cited on 2009 July 30]. Available from:hcp://grants.nih.gov/grants/guide/pa- files/pa- 98-102.html. Reasons for Chiroprac4c Clinicians to Provide Neuromusculoskeletal Evalua4on and Management Services Most people in pain, including those with chronic symptoms, go to primary care providers to get relief. But current systems of care do not adequately train or support internists, family physicians and pediatricians, the other health care providers who provide primary care in mee@ng the challenge of trea@ng pain as a chronic illness. Primary care providers osen receive licle training in the assessment and treatment of complex chronic pain condi@ons. American Pain Founda@on [Internet]. Pain resource guide: genng the help you need. 2009 June [cited on 2009 July 30]; pg 2. Available from: hcp://www.painfounda@on.org/learn/publica@ons/files/painresourceguide2009.pdf 2

Reasons for Chiroprac4c Clinicians to Provide Neuromusculoskeletal Evalua4on and Management Services Instead of receiving effec@ve relief, pa@ents with persistent pain osen find themselves in an endless cycle, seeing mul@ple health care providers, including many specialists in areas other than pain, who are not prepared to respond effec@vely. American Pain Founda@on [Internet]. Pain resource guide: genng the help you need. 2009 June [cited on 2009 July 30]; pg 2. Available from: hcp://www.painfounda@on.org/learn/publica@ons/files/painresourceguide2009.pdf Reasons for Chiroprac4c Clinicians to Provide Neuromusculoskeletal Evalua4on and Management Services They osen endure repeated tests and inadequate or unproven treatments. This may include unnecessary surgeries, injec@ons or procedures that have no long- term impact on comfort and func@on. Pa@ents with chronic pain have more hospital admissions, longer hospital stays, and unnecessary trips to the emergency department. Such inefficient and even wasteful treatment for pain is contribu@ng to the rapid rise in health care costs in the United States. American Pain Founda@on [Internet]. Pain resource guide: genng the help you need. 2009 June [cited on 2009 July 30]; pg 2. Available from: hcp://www.painfounda@on.org/learn/publica@ons/files/painresourceguide2009.pdf Reasons for Chiroprac4c Clinicians to Provide Neuromusculoskeletal Evalua4on and Management Services Adults aren t the only ones who suffer (with chronic pain). An es@mated 20 percent of children experience chronic pain and millions do not receive effec@ve pain relief. Children in pain osen bounce from doctor to doctor. If they do not get the appropriate treatment they are at risk of developing a pain condi@on that might remain into adulthood. Jones GT, Power C, Macfarlane GJ. Adverse events in childhood and chronic widespread pain in adult life: results from the 1958 Bri@sh birth cohort study. Pain 2009; 143(1-2):92-96. Reasons for Chiroprac4c Clinicians to Provide Neuromusculoskeletal Evalua4on and Management Services Ideally, all pa@ents with pain should obtain an appropriate assessment followed by a plan of care that reflects best prac@ces, to prevent the adverse effects of that pain both in the short term and over @me. Pa@ents with chronic pain should receive a model of care that matches their need, is safe, appropriate, cost - effec@ve, and guided by scien@fic evidence. They should also have access to a comprehensive approach, with a referral to pain specialists, when necessary. A Call to Revolu@onize Chronic Pain Care in America: An Opportunity in Health Care Reform. The Mayday Fund. November 4, 2009.Amended March 4, 2010. Learning Task Form groups of four Select a spokesperson Determine an appropriate evalua@on and management program for a pa@ent presen@ng with pain in the tailbone region for the past two years Present your report of findings with recommenda@ons 3

Evalua4on of a Chronic Pain Pa4ent Strategies for Evalua4ng the Pa4ent with Chronic Pain W. Clay Jackson, MD The Pain Prac@@oner Spring 2014 A comprehensive evalua6on of the pa6ent with chronic pain is rarely straigh9orward and it begins with the recogni6on that a complete cure is unlikely. Complica4ons The pa6ent s pain experience may be complicated by numerous factors, including lack of an obvious pathological cause, concomitant anxiety and depression, and a downward spiral of inac6vity and lowered self- esteem Medica4on Side Effects Modali4es ODen medica6ons used to treat the pain may themselves cause side effects that contribute to the pa6ent s reduced func6on. The skillful clinician will work with the pa6ent, incorpora6ng 6me- efficient tools to determine a treatment plan that combines a variety of modali6es and may or may not include the use of opioids. 4

Mutual Frustra4ons Valida4on of Pain With chronic pain pa6ents, the evalua6on is key: Failure to iden6fy all the factors that contribute to the pain can lead to ineffec6ve treatment, further deteriora6on, and mutual frustra6on, not to men6on legal and regulatory consequences. A seasoned clinician listens carefully to validate the pa6ent s pain without allowing elaborate descrip6ons to derail the 6ming and purpose of the visit. Goal of Treatment For most pa6ents with persistent pain, the goal of treatment is not complete relief of pain, but rather improvements in the pa6ent s physical and mental func6oning that result in an improved quality of life as he or she takes increasing responsibility in his or her own therapy. Outcomes Pa6ent and clinician may be traveling a long and bumpy road, but the outcome can be meaningful and beneficial for both. Evaluate and document the pa6ent s pain history including the nature, loca6on, intensity, and dura6on of the pain; current and prior pharmacological and non- pharmacological treatments; factors that worsen or improve the pain; underlying or coexis6ng condi6ons; and (importantly) the effect of the pain on the pa6ent s life. An assessment of func6on should include the impact of the pain on the pa6ent s family and social life, employment, and sleep, and provide a baseline for follow- up evalua6ons. 5

The clinician should also be alert to signs that the pa6ent is minimizing or maximizing the subjec6ve reports of the pain or, in cases of cogni6ve impairment, lacks the proper resources to describe it. Sir William Osler It is more important to consider what kind of pa6ent has the disease, rather than what kind of disease the pa6ent has Sir William Osler "He who studies medicine without books sails an uncharted sea, but he who studies medicine without pa@ents does not go to sea at all." Sir William Osler The contribu@on to medical educa@on of which he was proudest was his idea of clinical clerkship having third- and fourth- year students work with pa@ents on the wards. He pioneered the prac@ce of bedside teaching, making rounds with a handful of students, demonstra@ng what one student referred to as his method of "incomparably thorough physical examina@on." Sir William Osler Perhaps Osler's greatest contribu@on to medicine was to insist that students learn from seeing and talking to pa@ents and the establishment of the medical residency. Include ques6ons regarding depression, anxiety, PTSD, and other factors that might impact pain, including stress levels at home or at work. 6

Consider the pa6ent s capacity for chemical coping, or likelihood of using pain medica6on to cope with life s stresses. any evalua6on that may lead to a trial of opioids should include an assessment of the pa6ent s risk for opioid misuse, but it also should include a qualita6ve assessment of the pa6ent s goals. What are the pa6ent s func6onal goals? How does the pa6ent define func6onality? What are simple, concrete things the pa6ent wants to do in the next 30 days? How can treatment help the pa6ent reach her goals? A[empt to ascertain whether the pain is a part of the history or consumes the history. Which medica6ons has the pa6ent tried: NSAIDs Serotonin norepinepherinine reuptake inhibitors (SNRIs) Nerve cell membrane stabilizers (an6convulsants) And/or opioids Perform a focused physical examina6on based upon the pa6ent s history and carry out appropriate diagnos6c tes6ng. 7

Treatment Considera4ons Treatment Considera4ons The pa6ent- clinician rela6onship is best viewed as a collabora6ve partnership; whereas pa6ent demand should not determine the choice of a therapy, it should inform the choice. Many pa6ents want to combine complementary and alterna6ve medicine op6ons with pharmacological therapy, and the assessment will help determine which therapy will provide greatest benefit. Case 1 Subjec@ve data: 40 year- old female with pain in tailbone with sinng since falling on ice five (5) years earlier. Physical therapy and chiroprac@c manipula@on of the pelvis, lumbosacral and sacroiliac joints did not provide relief. She has been advised to undergo coccygectomy to relieve pain. Case 1 What type of examina@on procedures would your perform? Case 1 Record your examina@on and puta@ve objec@ve data, assessment and plan. Case 1 Assessment (Diagnoses): 1. Chronic pain syndrome, ICD 9: 338.21 2. Coccygodynia, ICD 9: 724.79 8

Coccygodynia The term 'coccygodynia' means the pain is in the tailbone area (os coccygis; coccyx). Coccygodynia Due to the sinng intolerance, coccygodynia can significantly disturb the quality of life. Coccygodynia Coccygeal disorders that could be manifested in coccygodynia are injuries (fracture, subluxa@on, luxa@on), abnormal mobility (hypermobility, anterior and posterior subluxa@on or luxa@on of the coccyx), disc degenera@on at sacrococcygeal (SC) and intercoccygeal (IC) segments, coccygeal spicule (bony excrescence), osteomyeli@s and tumors. Grgic V. Coccygodynia: e@ology, pathogenesis, clinical characteris@cs, diagnosis and therapy]. Lijec Vjesn. 2012 Jan- Feb;134(1-2):49-55. Coccygodynia: evalua4on and management Journal of the American Academy of Orthopaedic Surgeons 2004 Jan- Feb; 12(1): 49-54. Fogel GR, Cunningham PY 3rd, Esses SI. Spine Fellow, Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX 77030, USA. Coccygodynia is pain in the region of the coccyx. In most cases, abnormal mobility is seen on dynamic standing and seated radiographs, although the cause of pain is unknown in other pa@ents. Measure of the coccygeal incidence. A : standing film. B : sinng film, showing a normal flexion. C : measure of the angle (i); this angle reflects the theore@cal posi@on that the mobile part of the coccyx would take if the subject was "sinng without the seat", that is without any force ac@ng on it. M = coccygeal mobility, the angle by which the coccyx has rotated rela@ve to the sacrum. SPR = saggital pelvic rota@on, the angle by which the pelvis has rotated in going from standing to sinng. 9

Bone scans and magne@c resonance imaging may show inflamma@on and edema, but neither technique is as accurate as dynamic radiography. Hypermobility. On the les, standard film. On the right, film in the sinng posi@on, with the last joint of the coccyx lying horizontal. Subject is facing to the right. Luxa4on of Sacrococcygeal Joint Luxa@on of the first mobile vertebra in the sinng posi@on (right). Standard film on the les. Treatment for pa@ents with severe pain should begin with injec@on of local anesthe@c and cor@costeroid into the painful segment. Coccygeal massage and stretching of the levator ani muscle can help. Reduc4on of Coccygeal Subluxa4on or Luxa4on This maneuver is performed with a gentle reloca@on of the coccygeal segment. High velocity, low amplitude manipula@on is contraindicated. Lehman JJ 10

Internal Coccygeal Manual Medicine Procedure Inform pa@ent of procedure Gain permission to treat Medical assistant in treatment room Prepare pa@ent with gowning Lateral Decubitus Posi@on Interrupt examina@on/treatment if pain level is intolerable Check stability of sacrococcygeal joint Check for ac@ve trigger points in levator ani, coccygeal and obturator internus muscles Reduce subluxa@on or luxa@on Release ac@ve trigger points with myofascial trigger point pressure releases Lehman JJ Thiele GH. Coccygodynia: Cause and treatment. Diseases of the Colon and Rectum. November December, 1963, Volume 6, Issue 6, pp 422-436. Treatment by properly applied massage of the levator ani and coccygeus muscles, and at @mes, of the mesial fibers of the gluteus maximus muscle, cured or sa@sfactorily relieved 91.7 per cent of pa@ents treated. Coccygectomy is done only when nonsurgical treatment fails, which is infrequent. Coccygectomy usually is successful in carefully selected pa@ents, with the best results in those with radiographically demonstrated abnormali@es of coccygeal mobility. Spence, K. F., Jr.: Coccygectomy. Am. J. Surg.102: 850, 1961. Coccygectomy too osen yields disappoin@ng results, but is most likely to be of value in pa@ents in whom coccygodynia was caused by acute severe trauma. Case 2 A 19- year- old man fell on his bucocks 2 years before presenta@on and had immediate onset of coccygodynia. His symptoms were chronic and disabling. A, Lateral radiograph demonstrates posterior subluxa@on of the coccygeal mobile segment. B, Sagical T2- weighted spin- echo magne@c resonance image shows edema of the distal coccygeal segments, especially the subluxated coccygeal segment. 11

Learning Task This is an individual assignment Create a SOAP note for this pa@ent Determine an appropriate evalua@on and management program and present your report of findings with recommenda@ons Case 3 40- year- old man who presented with 8- month history of coccydynia that started aser he fell on coccyx while playing squash. He also complained of occasional tenesmus. Tenesmus Rectal tenesmus is a feeling of incomplete defeca@on. It is experienced as an inability or difficulty to empty the bowel at defeca@on, even if the bowel contents have already been excreted. It is frequently painful and may be accompanied by involuntary straining and other gastrointes@nal symptoms. Tenesmus has both a nocicep@ve as well as a neuropathic component, and is usually accompanied by intense pa@ent anxiety. Lateral radiograph of coccyx. Does the arrow s@mulate any concern? Differen4al Diagnosis What are the differen@al diagnoses that you would list in this case? Lateral radiograph of coccyx shows ly@c destruc@on of lower sacral segments and coccyx (arrow) 12

Differen4al Diagnosis The differen@al diagnoses in this case is sacrococcygeal chordoma, chondrosarcoma, aneurysmal bone cyst, giant cell tumor, plasmocytoma, metastasis, and sacrococcygeal teratoma. The Diagnosis is Sacrococcygeal Chordoma Chordoma Chordoma is a rare tumor that accounts for 2 4% of primary malignant osseous tumors. Disler DG, Miklic D. Imaging findings in tumors of the sacrum. AJR 1999; 173:1699-1706 Chordoma is a malignant tumor believed to arise from notochordal remnants. It is most osen found in the sacrococcygeal region (50%), followed by the skull base (35%) and the mobile spine (15%). Clinical manifesta@ons of sacral chordoma are osen subtle because it is a slow- growing lesion [2] and because it typically presents as a large presacral mass. Murphey MD, Andrews CL, Flemming DJ, Temple HT, Smith WS, Smirniotopoulos JG. From the archives of the AFIP: primary tumors of the spine radiologic pathologic correla@on. RadioGraphics 1996; 16:1131-1158 Management Pa@ent underwent an ultrasound- guided biopsy to prove the diagnosis and subsequent en bloc excision. The treatment of choice of sacral chordomas is wide excision leaving tumor- free margins. However, this treatment may not be possible in all pa@ents and is usually related to the large tumor volume. Radiotherapy is used for par@ally resectable or for inoperable tumors but has only a pallia@ve effect. The 5- year overall survival rate for pa@ents with these tumors is 50%. Gerber S, Ollivier L, Leclere J, et al. Imaging of sacral tumours. Skeletal Radiol 2008; 37:277-289 The Epidemic of Chronic Pain hcps://gamamed.org/opioidtraining/speaker3- presenta@on.pdf hcp://www.ncbi.nlm.nih.gov/books/nbk91497/ 13