& FIGUREs Netherlands Cancer Institute

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Facts & FIGUREs 2014-2015 Netherlands Cancer Institute

Comprehensive Cancer CentRE Research institute (The Netherlands Cancer Institute) Specialised clinic (Antoni van Leeuwenhoek hospital) Netherlands Cancer Institute = Comprehensive Cancer Centre + Core tasks Circulate knowledge about cancer Patient care Research Training Fundamental, translational and scientific clinical research Some examples of top-level clinical care DNA sequencing / tumor immunology / Intensity Modulated Radiation Therapy (IMRT) / Survivorship rehabilitation Timeline 1922 First internation 1913 1915 Inauguration Antoni van Leeuwenhoekhuis Keizer Foundation Nederlandsch Kankerinstituut

RESEARCH A nationally and internationally recognized centre of excellence conducting frontier scientific research. Income Research institute budget in 2014: 79.9 m euros 17.3 m Government (Ministry of Health, Welfare and Sport) 43.9 m Project grants 14.6 m Specific grant KWF Dutch Cancer Society including 8.8 m specific grants KWF Dutch Cancer Society 4.1 m Donations/bequests/patents al meeting of cancer researchers 1929 sgracht, first radition therapy machine comes into use Move to Sarphatistraat

Research projects The KWF Dutch Cancer Society awarded 14 of its 133 projects to the Netherlands Cancer Institute in 2014 20 active EU projects PhD research and publications 29 researchers gained their PhD in 2014 542 publications in scientific journals in 2014 Acquisition electron microscope 1960 1961 1968 Com Image guided Cobalt radiothe

PATIENT CARE The Netherlands Cancer Institute provides outstanding and up-to-date treatment. 1,557 patients participated in experimental treatment in 2014 1,790 second opinions in 2014 In 2014 34,311 unique patients were treated a 5% increase compared with 2013 2014 hospital budget 196 m 5,103 radiation therapy treatments in 2014 Move to Plesmanlaan Inauguration laboratory building 1973 1979 1988 missioning of first Linear Accelerator (LINAC) Inaugurat rapy unit comes into use

11 radiation therapy units Available capacity 12 operating theatres 220 beds including 50 day care beds Accreditations OECI accreditation (Comprehensive Cancer Centre) VMS accreditation (safety program) CCKL accreditation (laboratory research) NIAZ accreditation (radiotherapy) CZO accreditation (various education programs) Recognition by patients associations Pink ribbon breast cancer JACIE accreditation (stem cell transplantation) Patient information leaflet on prostate cancer Patient information leaflet on leukaemia and cancer of the lymph nodes Full marks for intestinal cancer care Care leaflet colostomy Care leaflet urostomy Acquisition MRI scanner 1993 2003 ion Gasthuis Opening new hospital

TRAINING The Netherlands Cancer Institute transfers knowledge to scientists, clinicians, nurses and students in the Netherlands and elsewhere. 18 training places for medical imaging and radiation experts 58 oncology nurses in advanced training course 2 oncology nurses in training for nurse specialist 24 internships for Bachelors of Nursing 45 doctors in medical specialty training 3 nurses in training for intensive care nurse New operating theaters, Intensive Care unit, Day care unit and Outpatients clinic 2013 2015 - Centenary - Hoofddorp radiotherapy branch - New animal laboratory facility

COOPERATION The Netherlands Cancer Institute cooperates with academic hospitals, universities, research institutes and patient organizations, both nationally or internationally. Forms of (inter)national cooperation Joint research Exchange of knowledge Consultancies & second opinions Some examples: Cancer Core Europe Center for Personalized Cancer Treatment (CPCT) Amsterdam Proton Therapy Center (APTC) (Inter)national oncological networks

STAFF The Netherlands Cancer Institute relies heavily on highly motivated and flexible staff who are dedicated to their work. Board of Directors René Medema, chairman Board of Directors, Director of Research Emile Voest, member Board of Directors, Medical Director Wim van Harten, member Board of Directors, Director Organization & Management Number of staff Number of staff in 2014: 2,491 Number of volunteers: 190 1,757 staff working in outpatient care, nursing, radiology, radiotherapy and support staff 168 566 medical specialists cancer research staff

Composition of staff 69% female 31% male 49% age between 30 and 50 22% under 30 29 % 50 or older The Netherlands Cancer Institute employs staff of 39 different nationalities Job satisfaction scores Results from the 2014 staff survey Enthusiasm Hospital Commitment Research institute Enthusiasm 7.7 7.4 8.2 7.7 7.6 Satisfaction Satisfaction

APPOINTMENTS AND SPECIAL GRANTS The Netherlands Cancer Institute is proud of the commitment and expertise of its staff. Queen Wilhelmina Research Prize (KWF Dutch Cancer Society) awarded to Ton Schumacher in 2014 NWO Vidi grant of 800,000 euros awarded to Robbie Joosten Thijn Brummelkamp elected EMBO member in 2014 Sjaak Neefjes appointed Foreign Member Norwegian Academy of Science and Letters Kees Jalink elected professor by special appointment at UvA Alpe d HuZes/KWF grant awared to Marjanka Schmidt Vici grant of 1.5 m euros awarded to Jos Jonkers and Huib Ovaa on behalf of the NWO as part of their Innovational Research Incentive Scheme

FUNDRAISING The Antoni van Leeuwenhoek Foundation raises funds for research into personalized cancer therapies, and links donors to research. 10,000 The Foundation s proceeds in 2014: Friends and donors support the Netherlands Cancer Institute 1.43 m MORE INFORMATION Plesmanlaan 121 1066 CX Amsterdam Tel. +31 (0)20 512 9111 The proceeds are used for research into resistance to chemotherapy, a device for personalized treatment, the biobank and immunotherapy July 2015, Netherlands Cancer Institute, PR&Communications www.avl.nl www.nki.nl www.avlfoundation.nl www.werkenbijavl.nl www.facebook.com/hetantonivanleeuwenhoek @hetavl www.youtube.com/user/nkiavl