CURRICULUM VITAE. József Lövey M.D. Ph.D.

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1 CURRICULUM VITAE József Lövey M.D. Ph.D. Personal Data Name József Lövey Address 5, Mester u. Pilisborosjenő 2097 Hungary Phone (361) Fax (361) Nationality Hungarian Date of birth: Residency Status EU citizen Marital Status: married, five children Qualification: MD: No: 252/1993 Date: , Semmelweis University of Medicine, Budapest, Hungary CCST: Radiation Oncology No: 1136/1997, Semmelweis University of Medicine, Budapest, Hungary CCST: Clinical Oncology No: 73/2000, Semmelweis University of Medicine, Budapest, Hungary Scientific degree Ph.D. (2006) Semmelweis University of Medicine, Ph.D. School

2 2 Habilitation University of Pécs Medical School (2011) Professional appreciation Treasurer of the Hungarian Society for Radiation Oncology ( ) President of the Hungarian Society for Radiation Oncology (2012- ) Board member of the Hungarian Society of Oncologists (since 2008) Current Position Consultant, deputy head of the Dept. of Radiotherapy National Institute Of Oncology Clinical director of the National Institute of Oncology Associate Professor, Semmelweis University, Budapest Language skills English, fluent Education Undergraduate: Martonhegyi Elementary School, Budapest, ( ) Pannonhalma Benedictine Boarding School, Pannonhalma ( ) University: Semmelweis University of Medicine Budapest ( ) 3 years pre-clinical 3 years clinical course MD: 1993, summa cum laude Postgraduate Education: Semmelweis University of Medicine, Haynal Imre Postgraduate Center, Budapest ( ) CCST: Radiation Oncology 1997 Semmelweis University of Medicine, Haynal Imre Postgraduate Center, Budapest ( ) CCST: Clinical Oncology 2000 Study tours abroad University of Pavia, Italy, San Matteo Hospital, Dept. of Internal Medicine Pavia, Italy

3 3 Coventry and Warwickshire Hospital, Dept. of Orthopaedic Surgery, Coventry, Great Britain, Rijksuniversiteit Gent, University Hospital, Dept. of Cardiology Gent, Belgium Children s Hospital, Halifax NS, Canada, University Hospital of Tours, Department of Radiotherapy Tours, France University of Heidelberg, Department of Radiotherapy and the German Cancer Research Institute, Heidelberg, Germany Wayne State University, Dept. of Radiotherapy, Detroit, MI, guest researcher, University of Heidelberg, Department of Radiotherapy and the German Cancer Research Institute, Heidelberg, Germany Teaching courses ESTRO Teaching Course on Modern Brachytherapy Techniques Tübingen, Germany ESTRO Teaching Course on Evidence Based Radiation Oncology, Budapest, Hungary, IAEA - Boston University School of Medicine Training Course on Medical Preparedness and Emergency Medical Assistance to Nuclear and Radiological Accidents, Budapest, Hungary, Description of clinical activity Previous Posts: House officer During the years of specialization in radiation oncology I was involved every type of service our Department provided. It included the inpatients care of 10 beds from the 67-bed inpatient unit. On call requirements 1 in 6 span the entire four years program. I went through the radiotherapy units of that time such as conventional X-ray, telecobalt unit, betatron, three

4 4 linear accelerators, whole body irradiation unit and HDR brachytherapy. From dimensional conformal radiotherapy planning was launched using Virtuos (Heidelberg) software. This period also contained elective programs in diagnostic radiology, surgery, head and neck surgery, gynaecology, and internal medicine. At the end of this period I was able to use all the available radiotherapy techniques in all kind of cancer patient. Form that time I was involved too in the financing of the radiation oncology department as the responsible person for the DRG coding of patients as an expert to the NHS and Ministry of Health. Registrar /Senior registrar After specializing in radiation oncology I worked in different positions partly in the inpatient service typically taking care of beds and in the outpatient service, most of the time at a linear accelerator. I was specially involved in gynaecological brachytherapy. I did one day outpatient clinic for consultations and follow up, and on call requirements were the same 1 in 6 span throughout this period. Beside of that I joined part time the laboratory of the Department of Tumour Progression of my Institute where I performed in vitro and in vivo experiments in the field of radiation sensitivity and radiation sensitization. In 2003 I spent four months at a tumour biology laboratory of the Department of Radiotherapy of the Wayne State University in Detroit, Michigan. Here I performed experiments on prostate cancer cells radiation sensitivity. From I entered the specialization training for clinical oncology, which included elective programs in the departments of solid tumors, haematooncology, urological oncology, dermatological oncology, surgical oncology, gynaecological oncology, head and neck surgery, diagnostic radiology and pathology. Following the specialty exam I was more and more involved in the development and implementation of concurrent chemoradiation protocols at our department. Consultant From 2005 I am section head of a linear accelerator, with two registrar and two house officers, treating approximately 60 outpatients and 10 inpatients per day. I supervise 12 inpatient bed working with a house officer. I am member of the gastrointestinal and lymphoma interdisciplinary team. I am responsible at my department for the concurrent chemoradiation protocols. I am also member of the prostate brachytherapy group. Since the beginning of 2007 I am a member of the interdisciplinary team for PET investigations for the central region of Hungary. My duties also include the supervision of the financial matters of

5 5 the radiotherapy department including the work in our controlling system. At our department we are introducing IMRT in clinical practice and I lead the team taking care of it. Deputy Department Head Practical leading activity in a deputy position of a high throughput radiotherapy department with 6500 new patient a year, extensive outpatient section and 69 bed inpatient unit. Director of International Relations Management of all international collaboration of the Institute including bilateral, multilateral and specific EU framework projects. Since 2010 also been appointed to be the LEAR (legally appointed representative) of the Institute in EU projects. Clinical director At this position the everyday running and management of the clinical activity of our comprehensive cancer centre belongs to my main duty. Addresses of Working Places Previous Working Places Department of Pharmacology, Semmelweis University of Medicine, Nagyvarad ter Budapest, Hungary Budapest - laboratory assistant ( ) Országos Onkológiai Intézet, 1122 Budapest, Ráth György u (1993- ) Department of Radiology and Oncotherapy, Semmelweis University 1085 Budapest, Ülli u. 26. (2012- ) Description of educational activity Since 1996 I give lectures regularly on the postgraduate courses of radiotherapy at the Semmelweis University, Budapest. I also take part in the practical postgraduate training. From 2007 I participate in the gradual medical education at the University of Pécs.

6 6 Between 2000 and 2004 I participated in the theoretical and practical training on medical emergency in nuclear and radiological accidents. Since 2010 I am the chair of Semmelweis University postgraduate program in radiation oncology Description of scientific activity Beside participation in clinical trials my main focus of cancer research is radiation sensitivity / radiation sensitization. I carried out basic research and have skills in laboratory methods such handling cell cultures, performing in vitro and in vivo (animal) experiments. Reviewed publications: 29 Cumulative impact factor: 33,358 Independent citation: 148 Involvement in clinical trials As a principal investigator I organized an institutional academic phase II-III. trial between 1996 and I participated in three international multicentric trials as investigator and as co-principal investigator. Currently I am a principal investigator of one phase III trial. Last ICH-GCP training completed in International relations I took part in the Work Package of National Cancer Control Plans of the Eurocan+Plus project. I coordinate the international relations of the Institute including projects in the EU framework programs. Member of the Accreditation Board of the OECI (Organization of European Cancer Institutes) Vice chair of the TRANSCAN ERA-NET consortium Budapest, 20 th of March, József Lövey

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